Drosophila melanogaster

18 known processes

PNUTS (Dmel_CG33526)

CG33526 gene product from transcript CG33526-RD

(Aliases: Dmel\CG33526,CG4124,PNUTSDm,CG31657,PNUTS-RB,CG33526)

PNUTS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.455
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.190
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.178
negative regulation of gene expression GO:0010629 387 0.161
chromatin organization GO:0006325 207 0.160
mitotic nuclear division GO:0007067 213 0.118
taxis GO:0042330 304 0.108
chemotaxis GO:0006935 249 0.104
protein localization to organelle GO:0033365 82 0.103
negative regulation of biosynthetic process GO:0009890 277 0.102
spindle organization GO:0007051 253 0.099
chromatin modification GO:0016568 147 0.098
endomembrane system organization GO:0010256 119 0.097
establishment of localization in cell GO:0051649 402 0.093
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.091
segmentation GO:0035282 207 0.090
positive regulation of macromolecule metabolic process GO:0010604 405 0.090
transcription from rna polymerase ii promoter GO:0006366 368 0.087
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.086
smad protein import into nucleus GO:0007184 11 0.082
positive regulation of response to stimulus GO:0048584 323 0.082
cellular macromolecule localization GO:0070727 220 0.082
protein localization GO:0008104 284 0.079
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.079
anterior posterior axis specification embryo GO:0008595 103 0.078
positive regulation of signaling GO:0023056 243 0.077
gene silencing GO:0016458 138 0.077
positive regulation of cell communication GO:0010647 250 0.077
organelle fission GO:0048285 340 0.076
phagocytosis GO:0006909 215 0.074
growth GO:0040007 359 0.071
regulation of mrna metabolic process GO:1903311 72 0.071
cell cycle checkpoint GO:0000075 95 0.070
appendage development GO:0048736 401 0.067
homeostatic process GO:0042592 199 0.063
phosphorylation GO:0016310 294 0.063
adult behavior GO:0030534 137 0.062
axon development GO:0061564 297 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.058
enzyme linked receptor protein signaling pathway GO:0007167 179 0.056
regulation of gene expression epigenetic GO:0040029 128 0.056
negative regulation of nucleic acid templated transcription GO:1903507 240 0.054
negative regulation of cellular metabolic process GO:0031324 382 0.053
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.053
death GO:0016265 284 0.052
regulation of rna splicing GO:0043484 69 0.052
imaginal disc derived appendage development GO:0048737 399 0.051
male gamete generation GO:0048232 201 0.051
cellular catabolic process GO:0044248 372 0.050
nuclear division GO:0000280 332 0.050
regulation of intracellular signal transduction GO:1902531 236 0.049
cellular protein localization GO:0034613 160 0.049
vesicle mediated transport GO:0016192 381 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.048
translation GO:0006412 69 0.048
protein complex assembly GO:0006461 200 0.048
negative regulation of cell cycle phase transition GO:1901988 103 0.048
embryonic axis specification GO:0000578 107 0.047
nucleocytoplasmic transport GO:0006913 72 0.047
positive regulation of signal transduction GO:0009967 223 0.047
positive regulation of nucleic acid templated transcription GO:1903508 266 0.046
negative regulation of rna biosynthetic process GO:1902679 240 0.046
intracellular signal transduction GO:0035556 300 0.045
dna replication GO:0006260 48 0.044
positive regulation of rna metabolic process GO:0051254 271 0.044
ras protein signal transduction GO:0007265 88 0.044
positive regulation of intracellular signal transduction GO:1902533 116 0.043
negative regulation of transcription dna templated GO:0045892 237 0.043
cell proliferation GO:0008283 299 0.043
blastoderm segmentation GO:0007350 159 0.042
tripartite regional subdivision GO:0007351 103 0.042
cellular protein modification process GO:0006464 438 0.042
positive regulation of biosynthetic process GO:0009891 316 0.042
regulation of localization GO:0032879 275 0.041
nucleus organization GO:0006997 45 0.040
positive regulation of transcription dna templated GO:0045893 266 0.040
imaginal disc derived wing morphogenesis GO:0007476 337 0.040
negative regulation of rna metabolic process GO:0051253 251 0.039
regulation of cellular localization GO:0060341 136 0.038
protein modification process GO:0036211 438 0.037
cell death GO:0008219 279 0.037
spermatid development GO:0007286 98 0.037
positive regulation of protein metabolic process GO:0051247 128 0.036
catabolic process GO:0009056 409 0.036
apoptotic process GO:0006915 159 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.035
intracellular transport GO:0046907 228 0.035
neuron projection guidance GO:0097485 241 0.035
macromolecular complex assembly GO:0065003 256 0.034
meiotic cell cycle GO:0051321 171 0.033
spermatogenesis GO:0007283 200 0.033
anterior posterior axis specification GO:0009948 109 0.033
regulation of mrna processing GO:0050684 71 0.032
positive regulation of gene expression GO:0010628 290 0.032
regulation of proteolysis GO:0030162 87 0.032
response to other organism GO:0051707 293 0.032
meiotic nuclear division GO:0007126 151 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
rna processing GO:0006396 147 0.032
embryonic pattern specification GO:0009880 174 0.032
regulation of programmed cell death GO:0043067 152 0.031
nuclear import GO:0051170 51 0.030
epithelial tube morphogenesis GO:0060562 88 0.030
regulation of phosphate metabolic process GO:0019220 210 0.030
axon guidance GO:0007411 233 0.030
establishment of protein localization GO:0045184 163 0.030
protein complex biogenesis GO:0070271 201 0.029
dna metabolic process GO:0006259 227 0.029
spermatid differentiation GO:0048515 114 0.029
rna splicing GO:0008380 83 0.029
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
regulation of mrna splicing via spliceosome GO:0048024 64 0.028
axis specification GO:0009798 167 0.028
mitotic cell cycle checkpoint GO:0007093 88 0.028
connective tissue development GO:0061448 3 0.028
anterior posterior pattern specification GO:0009952 136 0.028
chromatin silencing GO:0006342 76 0.028
response to temperature stimulus GO:0009266 106 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
macromolecule catabolic process GO:0009057 161 0.028
regulation of growth GO:0040008 233 0.027
muscle structure development GO:0061061 224 0.027
appendage morphogenesis GO:0035107 397 0.027
regulation of epithelial cell proliferation GO:0050678 4 0.027
centrosome organization GO:0051297 163 0.027
organic substance transport GO:0071702 257 0.027
single organism biosynthetic process GO:0044711 206 0.027
cytoplasmic transport GO:0016482 130 0.027
establishment of organelle localization GO:0051656 122 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
ribonucleotide metabolic process GO:0009259 145 0.026
mapk cascade GO:0000165 107 0.026
histone modification GO:0016570 106 0.026
cell motility GO:0048870 251 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
proteolysis GO:0006508 192 0.026
defense response to bacterium GO:0042742 178 0.025
single organism membrane organization GO:0044802 93 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.025
protein import GO:0017038 55 0.025
single organism cellular localization GO:1902580 180 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
regulation of cell death GO:0010941 173 0.025
single organism carbohydrate metabolic process GO:0044723 72 0.024
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
response to heat GO:0009408 63 0.024
response to abiotic stimulus GO:0009628 341 0.024
regulation of cell proliferation GO:0042127 163 0.024
protein import into nucleus GO:0006606 51 0.024
axonogenesis GO:0007409 290 0.024
protein phosphorylation GO:0006468 169 0.024
chemosensory behavior GO:0007635 106 0.024
nuclear transport GO:0051169 72 0.024
body morphogenesis GO:0010171 2 0.023
regulation of apoptotic process GO:0042981 130 0.023
cell migration GO:0016477 238 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.023
mrna metabolic process GO:0016071 124 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
response to light stimulus GO:0009416 124 0.023
kidney development GO:0001822 3 0.023
dephosphorylation GO:0016311 51 0.023
rhythmic process GO:0048511 106 0.022
regulation of cell differentiation GO:0045595 302 0.022
autophagy GO:0006914 108 0.022
chromatin remodeling GO:0006338 72 0.022
dendrite development GO:0016358 204 0.022
cellularization GO:0007349 90 0.022
erbb signaling pathway GO:0038127 58 0.022
single organism intracellular transport GO:1902582 207 0.022
single organism nuclear import GO:1902593 51 0.022
organic substance catabolic process GO:1901575 308 0.021
epithelial cell development GO:0002064 274 0.021
nitrogen compound transport GO:0071705 85 0.021
response to radiation GO:0009314 155 0.021
carbohydrate metabolic process GO:0005975 82 0.021
urogenital system development GO:0001655 72 0.021
aging GO:0007568 143 0.021
exocrine system development GO:0035272 162 0.021
positive regulation of lipid metabolic process GO:0045834 4 0.021
defense response to other organism GO:0098542 225 0.021
protein transport GO:0015031 155 0.020
organelle localization GO:0051640 148 0.020
spindle elongation GO:0051231 83 0.020
negative regulation of apoptotic process GO:0043066 63 0.020
regulation of mapk cascade GO:0043408 92 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
dna damage checkpoint GO:0000077 78 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
covalent chromatin modification GO:0016569 106 0.020
sister chromatid segregation GO:0000819 92 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
multi multicellular organism process GO:0044706 123 0.019
regulation of organelle organization GO:0033043 196 0.019
gland morphogenesis GO:0022612 145 0.019
chromosome condensation GO:0030261 41 0.019
protein dephosphorylation GO:0006470 27 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
regulation of immune system process GO:0002682 176 0.019
small gtpase mediated signal transduction GO:0007264 88 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
spindle assembly GO:0051225 80 0.018
heterocycle catabolic process GO:0046700 166 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
regulation of molecular function GO:0065009 217 0.018
developmental programmed cell death GO:0010623 138 0.018
positive regulation of cell motility GO:2000147 3 0.018
olfactory behavior GO:0042048 97 0.018
renal system development GO:0072001 72 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
regulation of hydrolase activity GO:0051336 97 0.018
mrna processing GO:0006397 104 0.018
cytoplasm organization GO:0007028 64 0.018
neurological system process GO:0050877 358 0.017
regulation of protein metabolic process GO:0051246 256 0.017
protein targeting to nucleus GO:0044744 51 0.017
germ line stem cell maintenance GO:0030718 50 0.017
regulation of catalytic activity GO:0050790 185 0.017
response to biotic stimulus GO:0009607 294 0.017
regulation of transport GO:0051049 181 0.017
positive regulation of molecular function GO:0044093 136 0.017
dendrite morphogenesis GO:0048813 199 0.017
ameboidal type cell migration GO:0001667 151 0.017
immune response GO:0006955 246 0.017
chromosome segregation GO:0007059 157 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.017
organic cyclic compound catabolic process GO:1901361 168 0.016
lateral inhibition GO:0046331 206 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
wnt signaling pathway GO:0016055 98 0.016
mitotic sister chromatid segregation GO:0000070 87 0.016
alternative mrna splicing via spliceosome GO:0000380 60 0.016
aromatic compound catabolic process GO:0019439 166 0.016
endocytosis GO:0006897 310 0.016
camera type eye development GO:0043010 4 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
single organism behavior GO:0044708 391 0.016
salivary gland morphogenesis GO:0007435 145 0.016
response to glucose GO:0009749 2 0.016
multicellular organismal aging GO:0010259 140 0.016
salivary gland development GO:0007431 162 0.016
translational initiation GO:0006413 11 0.016
secretion GO:0046903 109 0.016
regulation of phosphorylation GO:0042325 147 0.016
innate immune response GO:0045087 144 0.016
protein localization to nucleus GO:0034504 55 0.016
response to organic substance GO:0010033 284 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
negative regulation of gene expression epigenetic GO:0045814 77 0.016
regulation of catabolic process GO:0009894 170 0.016
nuclear envelope organization GO:0006998 7 0.015
response to sterol GO:0036314 34 0.015
dna packaging GO:0006323 91 0.015
extracellular structure organization GO:0043062 46 0.015
mitochondrion organization GO:0007005 65 0.015
mitotic spindle organization GO:0007052 220 0.015
cellular protein complex assembly GO:0043623 71 0.015
positive regulation of protein modification process GO:0031401 58 0.015
developmental pigmentation GO:0048066 68 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
developmental maturation GO:0021700 172 0.015
cellular carbohydrate metabolic process GO:0044262 22 0.015
protein targeting GO:0006605 64 0.015
sensory organ morphogenesis GO:0090596 260 0.015
salivary gland histolysis GO:0035070 88 0.015
intracellular protein transport GO:0006886 104 0.015
mrna splicing via spliceosome GO:0000398 73 0.015
pole plasm assembly GO:0007315 61 0.015
negative regulation of cell cycle GO:0045786 116 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
response to organophosphorus GO:0046683 2 0.014
mushroom body development GO:0016319 70 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
oxidation reduction process GO:0055114 123 0.014
eye morphogenesis GO:0048592 260 0.014
adult locomotory behavior GO:0008344 76 0.014
eye development GO:0001654 323 0.014
stem cell division GO:0017145 69 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
cellular lipid metabolic process GO:0044255 83 0.014
wing disc morphogenesis GO:0007472 344 0.014
regulation of cell cycle process GO:0010564 181 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
regulation of cell development GO:0060284 215 0.014
regulation of cytoplasmic transport GO:1903649 47 0.014
organelle assembly GO:0070925 198 0.014
muscle organ development GO:0007517 127 0.014
cell cycle phase transition GO:0044770 140 0.014
negative regulation of cell differentiation GO:0045596 143 0.013
regulation of immune response GO:0050776 118 0.013
reactive oxygen species metabolic process GO:0072593 22 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
negative regulation of cellular catabolic process GO:0031330 34 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
camera type eye morphogenesis GO:0048593 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
histolysis GO:0007559 102 0.013
response to monosaccharide GO:0034284 4 0.013
rna localization GO:0006403 115 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
regulation of ras protein signal transduction GO:0046578 93 0.012
dorsal ventral axis specification GO:0009950 66 0.012
dna conformation change GO:0071103 105 0.012
compound eye morphogenesis GO:0001745 249 0.012
regulation of hormone levels GO:0010817 40 0.012
energy derivation by oxidation of organic compounds GO:0015980 32 0.012
positive regulation of catabolic process GO:0009896 105 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
regulation of anatomical structure size GO:0090066 163 0.012
membrane organization GO:0061024 112 0.012
single organism catabolic process GO:0044712 228 0.012
defense response GO:0006952 300 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
spinal cord development GO:0021510 1 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
regulation of mitosis GO:0007088 56 0.012
small molecule metabolic process GO:0044281 305 0.012
pole plasm rna localization GO:0007316 52 0.012
pole plasm oskar mrna localization GO:0045451 46 0.012
cell cell junction organization GO:0045216 55 0.012
gene silencing by rna GO:0031047 57 0.012
positive regulation of phosphorylation GO:0042327 87 0.011
hindbrain development GO:0030902 2 0.011
pole plasm mrna localization GO:0019094 49 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
determination of adult lifespan GO:0008340 137 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
synaptic transmission GO:0007268 288 0.011
regionalization GO:0003002 416 0.011
purine containing compound metabolic process GO:0072521 155 0.011
programmed cell death GO:0012501 257 0.011
cellular protein catabolic process GO:0044257 83 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
epithelial cell migration GO:0010631 148 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
sperm competition GO:0046692 21 0.011
localization of cell GO:0051674 257 0.011
positive regulation of ras protein signal transduction GO:0046579 43 0.011
negative regulation of developmental process GO:0051093 201 0.011
protein maturation GO:0051604 71 0.011
negative regulation of neural precursor cell proliferation GO:2000178 27 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
compound eye development GO:0048749 307 0.011
wound healing GO:0042060 75 0.011
cell growth GO:0016049 108 0.011
tissue death GO:0016271 102 0.011
negative regulation of cell death GO:0060548 81 0.011
insemination GO:0007320 22 0.011
maintenance of location GO:0051235 73 0.011
mating GO:0007618 120 0.010
secretion by cell GO:0032940 101 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
respiratory system development GO:0060541 213 0.010
negative regulation of stem cell proliferation GO:2000647 30 0.010
rna transport GO:0050658 46 0.010
response to endogenous stimulus GO:0009719 119 0.010
response to bacterium GO:0009617 198 0.010
autophagic cell death GO:0048102 83 0.010
response to hexose GO:0009746 3 0.010
dorsal closure GO:0007391 79 0.010
regulation of response to stress GO:0080134 200 0.010
golgi organization GO:0007030 66 0.010
regulation of protein localization GO:0032880 76 0.010
rna catabolic process GO:0006401 37 0.010

PNUTS disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.013
musculoskeletal system disease DOID:17 0 0.011