Drosophila melanogaster

49 known processes

eys (Dmel_CG33955)

eyes shut

(Aliases: CG33955,CG7245,mAb 21A6,SPAM,spam,Dmel\CG33955,21A6,mAb21A6,CG15388,CG15389,EYS,spacemaker,CT35437,MAb21A6)

eys biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotory behavior GO:0007626 176 0.964
single organism behavior GO:0044708 391 0.815
photoreceptor cell differentiation GO:0046530 170 0.749
eye photoreceptor cell differentiation GO:0001754 145 0.737
compound eye morphogenesis GO:0001745 249 0.732
compound eye photoreceptor cell differentiation GO:0001751 140 0.580
compound eye photoreceptor development GO:0042051 78 0.572
eye morphogenesis GO:0048592 260 0.538
locomotor rhythm GO:0045475 56 0.410
sensory organ morphogenesis GO:0090596 260 0.381
neurological system process GO:0050877 358 0.375
adult behavior GO:0030534 137 0.359
taxis GO:0042330 304 0.335
Rat
rhabdomere development GO:0042052 38 0.318
eye photoreceptor cell development GO:0042462 81 0.313
rhythmic behavior GO:0007622 76 0.293
regulation of behavior GO:0050795 75 0.258
Rat
signal release GO:0023061 49 0.233
photoreceptor cell development GO:0042461 96 0.219
rhythmic process GO:0048511 106 0.212
g protein coupled receptor signaling pathway GO:0007186 136 0.212
establishment of localization in cell GO:0051649 402 0.199
detection of light stimulus GO:0009583 58 0.199
response to organic substance GO:0010033 284 0.185
detection of stimulus GO:0051606 156 0.180
single organism biosynthetic process GO:0044711 206 0.177
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.172
Mouse Rat
divalent metal ion transport GO:0070838 26 0.149
cell migration GO:0016477 238 0.136
enzyme linked receptor protein signaling pathway GO:0007167 179 0.130
positive regulation of molecular function GO:0044093 136 0.130
Mouse Rat
circadian rhythm GO:0007623 105 0.129
detection of external stimulus GO:0009581 66 0.127
regulation of intracellular signal transduction GO:1902531 236 0.124
Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.123
Mouse Rat
adult locomotory behavior GO:0008344 76 0.121
multi multicellular organism process GO:0044706 123 0.117
developmental pigmentation GO:0048066 68 0.115
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.112
retina development in camera type eye GO:0060041 4 0.111
intracellular signal transduction GO:0035556 300 0.110
compound eye development GO:0048749 307 0.110
regulation of molecular function GO:0065009 217 0.106
Mouse Rat
detection of visible light GO:0009584 38 0.104
secretion GO:0046903 109 0.102
multicellular organismal reproductive behavior GO:0033057 110 0.100
organonitrogen compound metabolic process GO:1901564 318 0.098
Mouse Rat
regulation of cellular localization GO:0060341 136 0.098
regulation of localization GO:0032879 275 0.097
Rat
circadian behavior GO:0048512 76 0.091
cellular response to chemical stimulus GO:0070887 199 0.091
small molecule metabolic process GO:0044281 305 0.090
Mouse Rat
response to oxygen containing compound GO:1901700 200 0.090
pigmentation GO:0043473 75 0.089
neurotransmitter transport GO:0006836 37 0.089
sensory perception of chemical stimulus GO:0007606 116 0.087
synaptic transmission GO:0007268 288 0.086
Mouse Rat
cell motility GO:0048870 251 0.086
regulation of phosphate metabolic process GO:0019220 210 0.083
Mouse Rat
learning GO:0007612 75 0.081
response to organophosphorus GO:0046683 2 0.077
learning or memory GO:0007611 141 0.077
neuron projection guidance GO:0097485 241 0.077
Rat
axonogenesis GO:0007409 290 0.073
Rat
response to light stimulus GO:0009416 124 0.071
sensory perception GO:0007600 196 0.071
calcium ion transport GO:0006816 24 0.071
response to radiation GO:0009314 155 0.070
response to organonitrogen compound GO:0010243 75 0.070
response to nitrogen compound GO:1901698 90 0.069
phototransduction GO:0007602 52 0.069
regulation of catalytic activity GO:0050790 185 0.066
Mouse Rat
carboxylic acid metabolic process GO:0019752 92 0.066
cellular response to organic substance GO:0071310 132 0.065
regulation of growth GO:0040008 233 0.065
Mouse
eye antennal disc development GO:0035214 60 0.063
localization of cell GO:0051674 257 0.063
regulation of synapse organization GO:0050807 110 0.062
Mouse
purine ribonucleotide metabolic process GO:0009150 145 0.062
Mouse Rat
tube morphogenesis GO:0035239 191 0.061
positive regulation of signaling GO:0023056 243 0.061
long term memory GO:0007616 62 0.060
positive regulation of macromolecule metabolic process GO:0010604 405 0.060
Mouse Rat
actin filament based process GO:0030029 220 0.058
eye development GO:0001654 323 0.058
cellular amino acid metabolic process GO:0006520 61 0.057
positive regulation of rna biosynthetic process GO:1902680 266 0.057
Mouse Rat
mesoderm development GO:0007498 78 0.057
regulation of transport GO:0051049 181 0.056
positive regulation of biosynthetic process GO:0009891 316 0.056
Mouse Rat
regulation of multicellular organismal development GO:2000026 414 0.056
Mouse Rat
positive regulation of catalytic activity GO:0043085 118 0.055
Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.055
flight behavior GO:0007629 26 0.054
organophosphate metabolic process GO:0019637 195 0.054
Mouse Rat
regulation of developmental pigmentation GO:0048070 24 0.053
salivary gland morphogenesis GO:0007435 145 0.052
nucleobase containing small molecule metabolic process GO:0055086 174 0.051
Mouse Rat
regionalization GO:0003002 416 0.051
positive regulation of phosphate metabolic process GO:0045937 139 0.050
Mouse Rat
male courtship behavior GO:0008049 63 0.050
cognition GO:0050890 141 0.050
response to temperature stimulus GO:0009266 106 0.050
oxoacid metabolic process GO:0043436 103 0.050
response to abiotic stimulus GO:0009628 341 0.049
positive regulation of nucleic acid templated transcription GO:1903508 266 0.047
Mouse Rat
regulation of locomotion GO:0040012 42 0.047
Rat
divalent inorganic cation transport GO:0072511 30 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.047
Mouse Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.046
Mouse Rat
mating behavior GO:0007617 106 0.046
regulation of cell cycle GO:0051726 291 0.046
axon guidance GO:0007411 233 0.046
Rat
organonitrogen compound biosynthetic process GO:1901566 117 0.045
cellular amine metabolic process GO:0044106 12 0.045
amine metabolic process GO:0009308 12 0.044
kidney development GO:0001822 3 0.044
regulation of neuron differentiation GO:0045664 103 0.044
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.044
memory GO:0007613 94 0.043
regulation of protein metabolic process GO:0051246 256 0.043
Mouse Rat
malpighian tubule development GO:0072002 64 0.042
response to endogenous stimulus GO:0009719 119 0.042
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.042
behavioral response to ethanol GO:0048149 49 0.041
nucleoside phosphate metabolic process GO:0006753 162 0.041
Mouse Rat
neuron recognition GO:0008038 101 0.041
actin cytoskeleton organization GO:0030036 206 0.040
multi organism behavior GO:0051705 175 0.039
regulation of cell differentiation GO:0045595 302 0.039
Rat
appendage development GO:0048736 401 0.039
regulation of anatomical structure size GO:0090066 163 0.039
positive regulation of neurotransmitter transport GO:0051590 2 0.039
male mating behavior GO:0060179 70 0.039
secretion by cell GO:0032940 101 0.039
positive regulation of cell communication GO:0010647 250 0.038
regulation of cellular ketone metabolic process GO:0010565 3 0.038
positive regulation of cellular component biogenesis GO:0044089 80 0.037
Mouse Rat
neuron fate commitment GO:0048663 50 0.037
organic substance catabolic process GO:1901575 308 0.036
Mouse Rat
positive regulation of gene expression GO:0010628 290 0.036
Mouse Rat
carbohydrate derivative metabolic process GO:1901135 217 0.036
Mouse Rat
embryonic hindgut morphogenesis GO:0048619 48 0.035
gastrulation with mouth forming first GO:0001703 36 0.035
positive regulation of protein metabolic process GO:0051247 128 0.034
Mouse Rat
photoreceptor cell fate commitment GO:0046552 41 0.034
chemotaxis GO:0006935 249 0.034
Rat
multi organism reproductive behavior GO:0044705 121 0.034
actomyosin structure organization GO:0031032 56 0.033
renal tubule morphogenesis GO:0061333 44 0.033
positive regulation of signal transduction GO:0009967 223 0.033
regulation of purine nucleotide metabolic process GO:1900542 62 0.033
Mouse Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.033
Rat
hindgut development GO:0061525 58 0.033
phosphorylation GO:0016310 294 0.033
Mouse Rat
gland development GO:0048732 191 0.033
cellular ketone metabolic process GO:0042180 24 0.033
olfactory learning GO:0008355 56 0.033
ion transport GO:0006811 145 0.033
detection of chemical stimulus GO:0009593 93 0.033
cell recognition GO:0008037 102 0.032
regulation of protein phosphorylation GO:0001932 64 0.032
Mouse Rat
purine containing compound metabolic process GO:0072521 155 0.032
Mouse Rat
response to organic cyclic compound GO:0014070 89 0.032
regulation of lyase activity GO:0051339 14 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
Mouse Rat
cellular catabolic process GO:0044248 372 0.030
Mouse Rat
regulation of neurotransmitter secretion GO:0046928 14 0.030
regulation of nervous system development GO:0051960 248 0.029
Mouse Rat
negative regulation of signaling GO:0023057 219 0.029
eye photoreceptor cell fate commitment GO:0042706 37 0.029
regulation of phosphorylation GO:0042325 147 0.029
Mouse Rat
positive regulation of cell development GO:0010720 61 0.028
neurotransmitter metabolic process GO:0042133 2 0.028
regulation of cell morphogenesis GO:0022604 163 0.028
Rat
neurotransmitter secretion GO:0007269 35 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
positive regulation of multicellular organismal process GO:0051240 143 0.027
Mouse
reproductive behavior GO:0019098 122 0.027
protein complex biogenesis GO:0070271 201 0.027
Rat
energy taxis GO:0009453 21 0.026
renal tubule development GO:0061326 64 0.026
cgmp biosynthetic process GO:0006182 8 0.026
cell division GO:0051301 248 0.026
negative regulation of cell communication GO:0010648 223 0.026
nucleoside metabolic process GO:0009116 127 0.026
Mouse Rat
positive regulation of nucleotide metabolic process GO:0045981 55 0.026
Rat
epidermal growth factor receptor signaling pathway GO:0007173 58 0.026
nephron epithelium development GO:0072009 3 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.025
purine ribonucleoside metabolic process GO:0046128 127 0.025
Mouse Rat
cyclic purine nucleotide metabolic process GO:0052652 25 0.025
response to alcohol GO:0097305 95 0.024
gastrulation involving germ band extension GO:0010004 36 0.024
organic acid metabolic process GO:0006082 103 0.024
regulation of neurogenesis GO:0050767 158 0.024
Rat
cellular response to endogenous stimulus GO:0071495 80 0.024
regulation of neurotransmitter levels GO:0001505 38 0.023
detection of stimulus involved in sensory perception GO:0050906 92 0.023
synapse assembly GO:0007416 143 0.022
Mouse Rat
regulation of cellular component biogenesis GO:0044087 201 0.022
Mouse Rat
developmental growth GO:0048589 280 0.022
Mouse
positive regulation of cell projection organization GO:0031346 29 0.022
Rat
regulation of protein modification process GO:0031399 112 0.022
Mouse Rat
lateral inhibition GO:0046331 206 0.022
guanosine containing compound catabolic process GO:1901069 74 0.022
Mouse Rat
response to wounding GO:0009611 94 0.022
positive regulation of response to stimulus GO:0048584 323 0.021
organ formation GO:0048645 39 0.021
synaptic target recognition GO:0008039 45 0.021
regulation of synapse assembly GO:0051963 94 0.020
Mouse
cuticle development GO:0042335 86 0.020
bolwig s organ morphogenesis GO:0001746 8 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
Mouse Rat
somatic stem cell division GO:0048103 37 0.020
forebrain development GO:0030900 2 0.020
purine containing compound catabolic process GO:0072523 112 0.020
Mouse Rat
positive regulation of cell motility GO:2000147 3 0.020
response to lipopolysaccharide GO:0032496 4 0.020
malpighian tubule morphogenesis GO:0007443 44 0.020
ribose phosphate metabolic process GO:0019693 145 0.019
Mouse Rat
regulation of secretion by cell GO:1903530 39 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.019
Mouse Rat
cellular nitrogen compound catabolic process GO:0044270 165 0.019
Mouse Rat
imaginal disc derived appendage development GO:0048737 399 0.019
nephron tubule development GO:0072080 3 0.019
regulation of neuron projection development GO:0010975 69 0.019
Rat
hindgut morphogenesis GO:0007442 58 0.019
cyclic nucleotide biosynthetic process GO:0009190 25 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.018
Mouse Rat
nucleotide metabolic process GO:0009117 161 0.018
Mouse Rat
purine nucleotide metabolic process GO:0006163 146 0.018
Mouse Rat
regulation of erbb signaling pathway GO:1901184 42 0.018
gland morphogenesis GO:0022612 145 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
Mouse Rat
signal transduction by phosphorylation GO:0023014 107 0.018
homeostatic process GO:0042592 199 0.018
establishment of organelle localization GO:0051656 122 0.018
chemosensory behavior GO:0007635 106 0.018
mapk cascade GO:0000165 107 0.018
response to alkaloid GO:0043279 26 0.018
cell proliferation GO:0008283 299 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.017
Mouse Rat
cation transport GO:0006812 110 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
Mouse Rat
positive regulation of hydrolase activity GO:0051345 78 0.017
Rat
cyclic nucleotide metabolic process GO:0009187 28 0.017
body morphogenesis GO:0010171 2 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
Mouse Rat
gastrulation GO:0007369 70 0.017
erbb signaling pathway GO:0038127 58 0.017
positive regulation of nervous system development GO:0051962 69 0.017
Mouse
positive regulation of transport GO:0051050 92 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
positive regulation of cell differentiation GO:0045597 64 0.017
single organism catabolic process GO:0044712 228 0.017
Mouse Rat
cellular response to carbohydrate stimulus GO:0071322 4 0.017
cell projection assembly GO:0030031 94 0.017
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
Mouse Rat
protein phosphorylation GO:0006468 169 0.016
Mouse Rat
pigment metabolic process GO:0042440 84 0.016
circadian sleep wake cycle GO:0042745 28 0.016
cardioblast cell fate specification GO:0042685 9 0.016
digestive tract development GO:0048565 149 0.016
purine containing compound biosynthetic process GO:0072522 30 0.016
negative regulation of gene expression GO:0010629 387 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
Mouse Rat
transcription from rna polymerase ii promoter GO:0006366 368 0.016
Mouse Rat
ribonucleotide metabolic process GO:0009259 145 0.016
Mouse Rat
proteolysis GO:0006508 192 0.016
regulation of axonogenesis GO:0050770 32 0.016
Rat
phenol containing compound metabolic process GO:0018958 57 0.015
synapse organization GO:0050808 196 0.015
Mouse Rat
neuroblast proliferation GO:0007405 74 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
Mouse Rat
purine nucleoside metabolic process GO:0042278 127 0.015
Mouse Rat
spermatogenesis GO:0007283 200 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
Rat
developmental growth involved in morphogenesis GO:0060560 65 0.015
wing disc morphogenesis GO:0007472 344 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
digestive system development GO:0055123 149 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
Mouse Rat
regulation of synaptic transmission GO:0050804 69 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
Mouse Rat
gene silencing GO:0016458 138 0.015
regulation of vesicle mediated transport GO:0060627 59 0.014
endocytosis GO:0006897 310 0.014
regulation of cell projection assembly GO:0060491 30 0.014
Rat
regulation of cellular component movement GO:0051270 42 0.014
Rat
regulation of cell migration GO:0030334 22 0.014
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.014
positive regulation of developmental process GO:0051094 143 0.014
Mouse
neuron neuron synaptic transmission GO:0007270 14 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
Rat
regulation of membrane potential GO:0042391 35 0.014
spinal cord development GO:0021510 1 0.014
stem cell division GO:0017145 69 0.014
organophosphate biosynthetic process GO:0090407 46 0.014
stem cell proliferation GO:0072089 88 0.014
tube formation GO:0035148 21 0.014
mrna metabolic process GO:0016071 124 0.014
neural retina development GO:0003407 4 0.014
regulation of mapk cascade GO:0043408 92 0.014
divalent inorganic cation homeostasis GO:0072507 29 0.014
telencephalon development GO:0021537 2 0.013
heterocycle catabolic process GO:0046700 166 0.013
Mouse Rat
positive regulation of neurotransmitter secretion GO:0001956 2 0.013
regulation of cell proliferation GO:0042127 163 0.013
positive regulation of synapse assembly GO:0051965 29 0.013
Mouse
hindbrain development GO:0030902 2 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
Mouse Rat
cellular macromolecular complex assembly GO:0034622 153 0.013
aromatic compound catabolic process GO:0019439 166 0.013
Mouse Rat
metal ion transport GO:0030001 74 0.013
axon development GO:0061564 297 0.013
Rat
tissue morphogenesis GO:0048729 297 0.013
regulation of cell size GO:0008361 63 0.013
phagocytosis GO:0006909 215 0.013
response to other organism GO:0051707 293 0.013
purine nucleotide biosynthetic process GO:0006164 29 0.013
exocrine system development GO:0035272 162 0.013
immune response activating signal transduction GO:0002757 2 0.012
cytosolic calcium ion transport GO:0060401 2 0.012
regulation of ion transport GO:0043269 39 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
Mouse Rat
organonitrogen compound catabolic process GO:1901565 128 0.012
Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
Mouse Rat
regulation of synapse structure and activity GO:0050803 128 0.012
Mouse
cellular homeostasis GO:0019725 80 0.012
eye pigment metabolic process GO:0042441 33 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
cellular response to organonitrogen compound GO:0071417 36 0.012
regulation of neurotransmitter transport GO:0051588 14 0.012
positive regulation of transferase activity GO:0051347 26 0.012
antennal development GO:0007469 25 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
Mouse Rat
macromolecular complex assembly GO:0065003 256 0.012
Rat
cellular response to biotic stimulus GO:0071216 4 0.012
muscle structure development GO:0061061 224 0.011
response to hormone GO:0009725 45 0.011
regulation of hemocyte differentiation GO:0045610 22 0.011
filopodium assembly GO:0046847 33 0.011
Rat
monocarboxylic acid transport GO:0015718 3 0.011
apoptotic process GO:0006915 159 0.011
Mouse
receptor clustering GO:0043113 3 0.011
Human Mouse Rat
immune system process GO:0002376 347 0.011
defense response GO:0006952 300 0.011
positive regulation of cell migration GO:0030335 2 0.011
detection of abiotic stimulus GO:0009582 66 0.011
regulation of response to external stimulus GO:0032101 115 0.011
Rat
epithelial tube morphogenesis GO:0060562 88 0.011
nucleotide catabolic process GO:0009166 109 0.011
Mouse Rat
sensory perception of light stimulus GO:0050953 12 0.011
camera type eye development GO:0043010 4 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
Mouse Rat
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
Mouse Rat
negative regulation of protein metabolic process GO:0051248 85 0.010
ribonucleotide biosynthetic process GO:0009260 28 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
regulation of actin filament based process GO:0032970 42 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
Mouse Rat
courtship behavior GO:0007619 68 0.010
negative regulation of catalytic activity GO:0043086 42 0.010
salivary gland development GO:0007431 162 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
regulation of cell projection organization GO:0031344 92 0.010
Rat
regulation of cell cycle process GO:0010564 181 0.010
mating GO:0007618 120 0.010
tetraterpenoid metabolic process GO:0016108 1 0.010
regulation of protein kinase activity GO:0045859 51 0.010
rhodopsin mediated signaling pathway GO:0016056 21 0.010
biological adhesion GO:0022610 138 0.010
central nervous system development GO:0007417 201 0.010

eys disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
sensory system disease DOID:0050155 0 0.014
nervous system disease DOID:863 0 0.014
eye and adnexa disease DOID:1492 0 0.010
disease of metabolism DOID:0014667 0 0.010