Drosophila melanogaster

26 known processes

IP3K2 (Dmel_CG34359)

Inositol 1,4,5-triphosphate kinase 2

(Aliases: Dmel_CG1630,IP[[3]]K2,Dmel\CG34359,CG34359,CG1630,NP2758,CG12724,Dmel_CG12724,D-IP3K2,dmIP[[3]]beta,DIP3K2,dmIP3Kbeta,dmIP3K2)

IP3K2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.228
oocyte development GO:0048599 124 0.182
response to oxidative stress GO:0006979 86 0.148
Fly
g protein coupled receptor signaling pathway GO:0007186 136 0.111
appendage development GO:0048736 401 0.108
homeostatic process GO:0042592 199 0.105
nucleoside phosphate metabolic process GO:0006753 162 0.102
response to reactive oxygen species GO:0000302 24 0.095
cell cell signaling involved in cell fate commitment GO:0045168 210 0.095
appendage morphogenesis GO:0035107 397 0.087
cell maturation GO:0048469 144 0.083
small molecule metabolic process GO:0044281 305 0.071
response to abiotic stimulus GO:0009628 341 0.071
imaginal disc derived appendage morphogenesis GO:0035114 395 0.070
ras protein signal transduction GO:0007265 88 0.069
imaginal disc derived wing morphogenesis GO:0007476 337 0.069
cellular protein modification process GO:0006464 438 0.068
Rat
organophosphate metabolic process GO:0019637 195 0.066
mitotic cytokinesis GO:0000281 50 0.064
imaginal disc derived appendage development GO:0048737 399 0.063
purine ribonucleotide metabolic process GO:0009150 145 0.063
carboxylic acid metabolic process GO:0019752 92 0.063
ribonucleotide metabolic process GO:0009259 145 0.061
cellular transition metal ion homeostasis GO:0046916 9 0.059
adult behavior GO:0030534 137 0.056
cytokinesis GO:0000910 90 0.055
small gtpase mediated signal transduction GO:0007264 88 0.055
cytoskeleton dependent cytokinesis GO:0061640 81 0.054
organic substance transport GO:0071702 257 0.054
negative regulation of multicellular organismal process GO:0051241 142 0.054
dna metabolic process GO:0006259 227 0.053
regulation of intracellular signal transduction GO:1902531 236 0.053
carbohydrate derivative metabolic process GO:1901135 217 0.052
nucleobase containing small molecule metabolic process GO:0055086 174 0.051
glycosyl compound catabolic process GO:1901658 112 0.051
positive regulation of phosphate metabolic process GO:0045937 139 0.051
exocrine system development GO:0035272 162 0.049
chemotaxis GO:0006935 249 0.048
autophagic cell death GO:0048102 83 0.046
wing disc morphogenesis GO:0007472 344 0.046
establishment of planar polarity GO:0001736 87 0.044
response to organic substance GO:0010033 284 0.043
negative regulation of cellular metabolic process GO:0031324 382 0.043
salivary gland morphogenesis GO:0007435 145 0.043
cellular response to chemical stimulus GO:0070887 199 0.043
morphogenesis of a polarized epithelium GO:0001738 93 0.041
phosphorylation GO:0016310 294 0.041
cell proliferation GO:0008283 299 0.041
response to ethanol GO:0045471 59 0.040
oxoacid metabolic process GO:0043436 103 0.039
positive regulation of molecular function GO:0044093 136 0.039
cellular amino acid metabolic process GO:0006520 61 0.038
regulation of ras protein signal transduction GO:0046578 93 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.038
organonitrogen compound metabolic process GO:1901564 318 0.037
positive regulation of cell migration GO:0030335 2 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
regulation of cellular catabolic process GO:0031329 157 0.036
purine ribonucleoside metabolic process GO:0046128 127 0.036
regulation of catabolic process GO:0009894 170 0.036
regulation of phosphate metabolic process GO:0019220 210 0.036
forebrain development GO:0030900 2 0.036
cell division GO:0051301 248 0.036
regulation of gtpase activity GO:0043087 44 0.035
cellular response to extracellular stimulus GO:0031668 64 0.035
cell death GO:0008219 279 0.035
metal ion homeostasis GO:0055065 44 0.034
l amino acid import GO:0043092 2 0.034
regulation of small gtpase mediated signal transduction GO:0051056 93 0.034
regulation of nucleotide metabolic process GO:0006140 62 0.034
positive regulation of phosphorus metabolic process GO:0010562 139 0.033
regulation of phosphorus metabolic process GO:0051174 210 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
salivary gland cell autophagic cell death GO:0035071 83 0.033
regulation of oocyte development GO:0060281 27 0.032
intracellular signal transduction GO:0035556 300 0.032
nucleotide catabolic process GO:0009166 109 0.031
developmental growth GO:0048589 280 0.031
developmental growth involved in morphogenesis GO:0060560 65 0.031
endocytosis GO:0006897 310 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
cellular response to reactive oxygen species GO:0034614 14 0.031
response to endogenous stimulus GO:0009719 119 0.030
nucleotide metabolic process GO:0009117 161 0.030
cellular homeostasis GO:0019725 80 0.030
gtp metabolic process GO:0046039 72 0.030
detection of stimulus GO:0051606 156 0.029
single organism catabolic process GO:0044712 228 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
lateral inhibition GO:0046331 206 0.029
negative regulation of biosynthetic process GO:0009890 277 0.028
developmental maturation GO:0021700 172 0.028
rho protein signal transduction GO:0007266 14 0.028
purine nucleoside catabolic process GO:0006152 112 0.028
salivary gland development GO:0007431 162 0.028
meiotic cell cycle GO:0051321 171 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.028
purine containing compound metabolic process GO:0072521 155 0.028
nuclear division GO:0000280 332 0.028
nucleobase containing compound catabolic process GO:0034655 165 0.028
cellular response to oxidative stress GO:0034599 28 0.027
tissue death GO:0016271 102 0.027
ion transport GO:0006811 145 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
nucleoside phosphate catabolic process GO:1901292 110 0.027
meiotic nuclear division GO:0007126 151 0.026
catabolic process GO:0009056 409 0.026
axon extension GO:0048675 32 0.026
taxis GO:0042330 304 0.025
regulation of response to stress GO:0080134 200 0.025
axonogenesis GO:0007409 290 0.025
membrane organization GO:0061024 112 0.025
organic acid metabolic process GO:0006082 103 0.025
response to nutrient levels GO:0031667 114 0.025
oocyte differentiation GO:0009994 145 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.025
gland morphogenesis GO:0022612 145 0.024
positive regulation of cell motility GO:2000147 3 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.024
negative regulation of insulin secretion GO:0046676 1 0.024
histolysis GO:0007559 102 0.024
protein heterooligomerization GO:0051291 4 0.023
response to radiation GO:0009314 155 0.023
cellular response to nutrient levels GO:0031669 62 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
short term memory GO:0007614 19 0.023
gtp catabolic process GO:0006184 72 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
single organism biosynthetic process GO:0044711 206 0.023
positive regulation of signal transduction GO:0009967 223 0.023
amine metabolic process GO:0009308 12 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
death GO:0016265 284 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
developmental programmed cell death GO:0010623 138 0.022
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
dendrite morphogenesis GO:0048813 199 0.022
Rat
carbohydrate derivative biosynthetic process GO:1901137 85 0.022
ribonucleotide catabolic process GO:0009261 109 0.022
nucleoside catabolic process GO:0009164 112 0.022
regulation of cell proliferation GO:0042127 163 0.022
phagocytosis GO:0006909 215 0.022
behavioral response to ethanol GO:0048149 49 0.022
actin filament based process GO:0030029 220 0.022
Rat
cellular catabolic process GO:0044248 372 0.022
response to extracellular stimulus GO:0009991 116 0.021
chromatin organization GO:0006325 207 0.021
cation homeostasis GO:0055080 51 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
cognition GO:0050890 141 0.021
cellular response to external stimulus GO:0071496 66 0.021
male meiosis GO:0007140 52 0.021
connective tissue development GO:0061448 3 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
response to gravity GO:0009629 26 0.021
regulation of cellular component biogenesis GO:0044087 201 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
response to starvation GO:0042594 97 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
chromosome organization GO:0051276 360 0.020
leg disc morphogenesis GO:0007478 80 0.020
response to light stimulus GO:0009416 124 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
purine containing compound catabolic process GO:0072523 112 0.020
mesoderm development GO:0007498 78 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
regulation of apoptotic process GO:0042981 130 0.020
response to copper ion GO:0046688 4 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
nucleoside metabolic process GO:0009116 127 0.020
regulation of molecular function GO:0065009 217 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
oxidation reduction process GO:0055114 123 0.019
positive regulation of nucleoside metabolic process GO:0045979 47 0.019
organelle fission GO:0048285 340 0.019
establishment of tissue polarity GO:0007164 87 0.019
salivary gland histolysis GO:0035070 88 0.019
tissue morphogenesis GO:0048729 297 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
organic substance catabolic process GO:1901575 308 0.019
memory GO:0007613 94 0.019
learning GO:0007612 75 0.019
single organism behavior GO:0044708 391 0.019
regulation of cell morphogenesis GO:0022604 163 0.018
Rat
signal transduction by phosphorylation GO:0023014 107 0.018
proteolysis GO:0006508 192 0.018
negative regulation of developmental process GO:0051093 201 0.018
negative regulation of cell communication GO:0010648 223 0.018
developmental pigmentation GO:0048066 68 0.018
negative regulation of signaling GO:0023057 219 0.018
regulation of localization GO:0032879 275 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
response to oxygen containing compound GO:1901700 200 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
regulation of nucleotide catabolic process GO:0030811 48 0.018
cellular cation homeostasis GO:0030003 38 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
protein modification process GO:0036211 438 0.018
Rat
imaginal disc derived leg morphogenesis GO:0007480 80 0.017
heterocycle catabolic process GO:0046700 166 0.017
response to alcohol GO:0097305 95 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
apoptotic process GO:0006915 159 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
cellular metal ion homeostasis GO:0006875 31 0.017
response to biotic stimulus GO:0009607 294 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.016
positive regulation of immune system process GO:0002684 68 0.016
programmed cell death GO:0012501 257 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
germ cell migration GO:0008354 43 0.016
monocarboxylic acid transport GO:0015718 3 0.015
positive regulation of protein modification process GO:0031401 58 0.015
regulation of multi organism process GO:0043900 131 0.015
organelle localization GO:0051640 148 0.015
l glutamate import GO:0051938 1 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
regulation of cell death GO:0010941 173 0.015
learning or memory GO:0007611 141 0.015
monovalent inorganic cation transport GO:0015672 40 0.015
response to monosaccharide GO:0034284 4 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
gland development GO:0048732 191 0.015
protein phosphorylation GO:0006468 169 0.015
Rat
ribose phosphate biosynthetic process GO:0046390 28 0.015
mapk cascade GO:0000165 107 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
Rat
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.015
dendrite development GO:0016358 204 0.014
Rat
cellular amine metabolic process GO:0044106 12 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
neuron projection guidance GO:0097485 241 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
immune system process GO:0002376 347 0.014
regulation of programmed cell death GO:0043067 152 0.014
cholesterol homeostasis GO:0042632 3 0.014
mitotic sister chromatid segregation GO:0000070 87 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
positive regulation of nucleotide catabolic process GO:0030813 46 0.014
transition metal ion homeostasis GO:0055076 17 0.014
regulation of reproductive process GO:2000241 54 0.014
protein processing GO:0016485 68 0.014
regulation of protein metabolic process GO:0051246 256 0.014
oocyte construction GO:0007308 112 0.013
regulation of gtp catabolic process GO:0033124 44 0.013
positive regulation of catabolic process GO:0009896 105 0.013
tube morphogenesis GO:0035239 191 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
regulation of organelle organization GO:0033043 196 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
detection of light stimulus GO:0009583 58 0.013
single organism membrane organization GO:0044802 93 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
motor neuron axon guidance GO:0008045 58 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
regulation of immune system process GO:0002682 176 0.013
positive regulation of cell communication GO:0010647 250 0.013
regulation of ras gtpase activity GO:0032318 38 0.013
protein transport GO:0015031 155 0.013
sister chromatid segregation GO:0000819 92 0.013
regulation of mapk cascade GO:0043408 92 0.013
male gamete generation GO:0048232 201 0.013
regulation of cell cycle GO:0051726 291 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
establishment of localization in cell GO:0051649 402 0.012
body morphogenesis GO:0010171 2 0.012
ocellus pigment metabolic process GO:0046158 19 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
pigment biosynthetic process GO:0046148 36 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
response to organic cyclic compound GO:0014070 89 0.012
mitotic nuclear division GO:0007067 213 0.012
regulation of transport GO:0051049 181 0.012
regulation of response to wounding GO:1903034 19 0.012
spermatid development GO:0007286 98 0.012
regulation of anatomical structure size GO:0090066 163 0.012
erbb signaling pathway GO:0038127 58 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
organophosphate catabolic process GO:0046434 112 0.012
response to growth factor GO:0070848 31 0.012
cellular protein catabolic process GO:0044257 83 0.012
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.012
leg disc development GO:0035218 92 0.012
cellular response to starvation GO:0009267 61 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
segmentation GO:0035282 207 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
Rat
cation transport GO:0006812 110 0.012
response to glucose GO:0009749 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
regionalization GO:0003002 416 0.011
detection of chemical stimulus GO:0009593 93 0.011
regulation of neuron differentiation GO:0045664 103 0.011
Rat
cellular response to molecule of bacterial origin GO:0071219 3 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
limb development GO:0060173 1 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
positive regulation of gene expression GO:0010628 290 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
positive regulation of developmental process GO:0051094 143 0.011
Rat
cellular response to dna damage stimulus GO:0006974 223 0.011
endomembrane system organization GO:0010256 119 0.011
positive regulation of signaling GO:0023056 243 0.011
regulation of cell projection organization GO:0031344 92 0.011
Rat
ommochrome metabolic process GO:0046152 19 0.011
cellular response to hydrogen peroxide GO:0070301 7 0.011
wnt signaling pathway GO:0016055 98 0.011
response to hypoxia GO:0001666 53 0.011
response to lipopolysaccharide GO:0032496 4 0.011
regulation of phosphorylation GO:0042325 147 0.011
regulation of membrane potential GO:0042391 35 0.011
regulation of cell adhesion GO:0030155 27 0.011
protein localization GO:0008104 284 0.011
organ formation GO:0048645 39 0.011
axis elongation GO:0003401 3 0.011
macromolecular complex assembly GO:0065003 256 0.011
eye pigment metabolic process GO:0042441 33 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
chemical homeostasis GO:0048878 92 0.011
myotube cell development GO:0014904 3 0.011
vesicle mediated transport GO:0016192 381 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
regulation of response to external stimulus GO:0032101 115 0.010
cellular ketone metabolic process GO:0042180 24 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
regulation of behavior GO:0050795 75 0.010
organic acid transport GO:0015849 18 0.010
peptidyl threonine modification GO:0018210 3 0.010
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.010
developmental cell growth GO:0048588 52 0.010
positive regulation of response to wounding GO:1903036 15 0.010
regulation of steroid metabolic process GO:0019218 2 0.010
cell growth GO:0016049 108 0.010
locomotory behavior GO:0007626 176 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
negative regulation of cell death GO:0060548 81 0.010
spermatogenesis GO:0007283 200 0.010
microtubule organizing center organization GO:0031023 168 0.010
regulation of reactive oxygen species metabolic process GO:2000377 8 0.010

IP3K2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.225
Human
nervous system disease DOID:863 0 0.054
central nervous system disease DOID:331 0 0.027
neurodegenerative disease DOID:1289 0 0.021
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.017
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011