Drosophila melanogaster

85 known processes

Rpt4 (Dmel_CG3455)

CG3455 gene product from transcript CG3455-RA

(Aliases: l(1)G0114,l(1)G0227,Dmel\CG3455,l(1)G0345,CG3455,Dm_Rpt4b,Dm_Rpt4a,p42D,Dmp42D)

Rpt4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 143 0.873
Worm
cellular protein catabolic process GO:0044257 83 0.853
Yeast
proteasome assembly GO:0043248 2 0.824
Yeast
modification dependent protein catabolic process GO:0019941 78 0.769
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.744
Yeast
mitotic spindle organization GO:0007052 220 0.718
proteolysis GO:0006508 192 0.707
spindle organization GO:0007051 253 0.706
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.700
Yeast
ubiquitin dependent protein catabolic process GO:0006511 78 0.694
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.649
modification dependent macromolecule catabolic process GO:0043632 79 0.603
Yeast
multicellular organismal aging GO:0010259 140 0.601
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.594
Yeast
proteasomal protein catabolic process GO:0010498 59 0.564
Yeast
protein catabolic process GO:0030163 101 0.540
Yeast
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.531
cellular response to dna damage stimulus GO:0006974 223 0.515
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.463
Yeast
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.443
Yeast
spindle elongation GO:0051231 83 0.442
mitotic nuclear division GO:0007067 213 0.435
spindle assembly GO:0051225 80 0.326
nuclear division GO:0000280 332 0.321
spindle assembly involved in mitosis GO:0090307 50 0.313
larval development GO:0002164 104 0.312
Worm
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.311
Yeast
apoptotic process GO:0006915 159 0.311
dna templated transcription initiation GO:0006352 25 0.310
Yeast
nucleotide excision repair GO:0006289 8 0.307
Yeast
organic substance catabolic process GO:1901575 308 0.307
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.306
Worm
positive regulation of endopeptidase activity GO:0010950 26 0.288
positive regulation of peptidase activity GO:0010952 29 0.272
catabolic process GO:0009056 409 0.268
Yeast
positive regulation of proteolysis GO:0045862 52 0.264
organelle fission GO:0048285 340 0.262
cell death GO:0008219 279 0.251
cellular catabolic process GO:0044248 372 0.248
Yeast
organelle assembly GO:0070925 198 0.240
macromolecule catabolic process GO:0009057 161 0.238
Yeast
determination of adult lifespan GO:0008340 137 0.235
Worm
regulation of proteolysis GO:0030162 87 0.220
organonitrogen compound metabolic process GO:1901564 318 0.215
multicellular organismal reproductive behavior GO:0033057 110 0.213
death GO:0016265 284 0.209
purine ribonucleoside metabolic process GO:0046128 127 0.196
regulation of cell cycle process GO:0010564 181 0.170
mitotic spindle elongation GO:0000022 81 0.156
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.154
Yeast
regulation of mitotic cell cycle GO:0007346 190 0.154
protein complex biogenesis GO:0070271 201 0.142
Yeast
cell proliferation GO:0008283 299 0.139
protein complex assembly GO:0006461 200 0.131
Yeast
dna templated transcription elongation GO:0006354 18 0.127
Yeast
regulation of cell cycle GO:0051726 291 0.118
cellular macromolecular complex assembly GO:0034622 153 0.117
Yeast
negative regulation of response to stimulus GO:0048585 258 0.114
negative regulation of signaling GO:0023057 219 0.109
nucleoside phosphate metabolic process GO:0006753 162 0.108
cullin deneddylation GO:0010388 3 0.099
response to organic substance GO:0010033 284 0.099
regulation of endopeptidase activity GO:0052548 36 0.096
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.095
regulation of cellular component biogenesis GO:0044087 201 0.094
Yeast
regulation of multicellular organismal development GO:2000026 414 0.090
protein deneddylation GO:0000338 8 0.090
positive regulation of molecular function GO:0044093 136 0.089
organophosphate metabolic process GO:0019637 195 0.088
purine nucleoside metabolic process GO:0042278 127 0.086
camera type eye development GO:0043010 4 0.084
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.081
regulation of cell division GO:0051302 72 0.080
programmed cell death GO:0012501 257 0.079
nucleoside triphosphate metabolic process GO:0009141 120 0.077
ribose phosphate metabolic process GO:0019693 145 0.075
nucleoside phosphate catabolic process GO:1901292 110 0.072
regulation of peptidase activity GO:0052547 39 0.072
regulation of catabolic process GO:0009894 170 0.072
aromatic compound catabolic process GO:0019439 166 0.071
organophosphate catabolic process GO:0046434 112 0.069
macromolecular complex assembly GO:0065003 256 0.068
Yeast
multi multicellular organism process GO:0044706 123 0.068
peptide metabolic process GO:0006518 80 0.068
organic cyclic compound catabolic process GO:1901361 168 0.067
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.067
immune system process GO:0002376 347 0.067
positive regulation of rna metabolic process GO:0051254 271 0.067
negative regulation of cell communication GO:0010648 223 0.064
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.063
regulation of molecular function GO:0065009 217 0.061
nucleotide catabolic process GO:0009166 109 0.061
mitotic cell cycle phase transition GO:0044772 138 0.060
nucleoside catabolic process GO:0009164 112 0.059
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.059
regulation of hydrolase activity GO:0051336 97 0.059
centrosome organization GO:0051297 163 0.058
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
multi organism behavior GO:0051705 175 0.054
negative regulation of gene expression GO:0010629 387 0.054
carbohydrate derivative catabolic process GO:1901136 118 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.053
purine ribonucleotide catabolic process GO:0009154 109 0.053
regulation of cellular catabolic process GO:0031329 157 0.052
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.051
Yeast
protein transport GO:0015031 155 0.051
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.050
protein dna complex subunit organization GO:0071824 86 0.050
Yeast
purine nucleoside catabolic process GO:0006152 112 0.050
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.049
purine nucleotide catabolic process GO:0006195 109 0.049
dna metabolic process GO:0006259 227 0.049
Yeast
centrosome duplication GO:0051298 121 0.048
ribonucleoside triphosphate metabolic process GO:0009199 119 0.048
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.047
nucleoside metabolic process GO:0009116 127 0.047
positive regulation of cell death GO:0010942 69 0.047
cellular protein modification process GO:0006464 438 0.046
regulation of proteasomal protein catabolic process GO:0061136 39 0.045
nucleobase containing compound catabolic process GO:0034655 165 0.045
dna repair GO:0006281 54 0.045
Yeast
positive regulation of catalytic activity GO:0043085 118 0.044
ribonucleoside catabolic process GO:0042454 112 0.044
regulation of mitosis GO:0007088 56 0.043
negative regulation of cell cycle process GO:0010948 109 0.042
ribonucleoside triphosphate catabolic process GO:0009203 108 0.042
ribonucleotide catabolic process GO:0009261 109 0.042
establishment of localization in cell GO:0051649 402 0.041
regulation of mitotic sister chromatid separation GO:0010965 28 0.040
negative regulation of signal transduction GO:0009968 206 0.040
purine ribonucleotide metabolic process GO:0009150 145 0.039
positive regulation of cellular catabolic process GO:0031331 95 0.039
organonitrogen compound catabolic process GO:1901565 128 0.037
regulation of intracellular signal transduction GO:1902531 236 0.036
photoreceptor cell differentiation GO:0046530 170 0.036
single organism catabolic process GO:0044712 228 0.035
positive regulation of catabolic process GO:0009896 105 0.034
regulation of cellular protein catabolic process GO:1903362 44 0.033
ribonucleoside metabolic process GO:0009119 127 0.033
mitotic g2 m transition checkpoint GO:0044818 70 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.033
nucleotide metabolic process GO:0009117 161 0.032
positive regulation of cellular component organization GO:0051130 156 0.032
Yeast
centrosome cycle GO:0007098 137 0.032
regulation of cellular protein metabolic process GO:0032268 243 0.032
purine nucleoside monophosphate catabolic process GO:0009128 38 0.032
ribonucleotide metabolic process GO:0009259 145 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.031
heterocycle catabolic process GO:0046700 166 0.031
regulation of cell differentiation GO:0045595 302 0.031
purine nucleoside monophosphate metabolic process GO:0009126 50 0.031
neurological system process GO:0050877 358 0.031
regulation of nuclear division GO:0051783 58 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.031
intracellular signal transduction GO:0035556 300 0.031
purine nucleoside triphosphate metabolic process GO:0009144 119 0.031
regulation of catalytic activity GO:0050790 185 0.030
purine nucleotide metabolic process GO:0006163 146 0.030
developmental growth GO:0048589 280 0.030
purine nucleoside triphosphate catabolic process GO:0009146 108 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.030
cellular component assembly involved in morphogenesis GO:0010927 151 0.029
purine ribonucleoside catabolic process GO:0046130 112 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
atp catabolic process GO:0006200 38 0.028
body morphogenesis GO:0010171 2 0.028
Worm
protein neddylation GO:0045116 5 0.028
positive regulation of gene expression GO:0010628 290 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.027
nucleoside monophosphate catabolic process GO:0009125 39 0.026
regulation of cell development GO:0060284 215 0.026
purine containing compound catabolic process GO:0072523 112 0.025
negative regulation of multicellular organismal process GO:0051241 142 0.025
regulation of behavior GO:0050795 75 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.025
mitotic g2 dna damage checkpoint GO:0007095 69 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
positive regulation of programmed cell death GO:0043068 62 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.024
telencephalon development GO:0021537 2 0.024
cell motility GO:0048870 251 0.023
rna splicing via transesterification reactions GO:0000375 73 0.023
positive regulation of hydrolase activity GO:0051345 78 0.023
single organism cellular localization GO:1902580 180 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
cellular amide metabolic process GO:0043603 80 0.022
carbohydrate metabolic process GO:0005975 82 0.022
chromosome separation GO:0051304 42 0.022
smoothened signaling pathway GO:0007224 49 0.021
ribonucleoside monophosphate catabolic process GO:0009158 39 0.021
humoral immune response GO:0006959 117 0.021
negative regulation of rna metabolic process GO:0051253 251 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
protein localization GO:0008104 284 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
cell division GO:0051301 248 0.021
regionalization GO:0003002 416 0.021
small gtpase mediated signal transduction GO:0007264 88 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
regulation of protein catabolic process GO:0042176 55 0.020
regulation of endocytosis GO:0030100 37 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
regulation of mitotic sister chromatid segregation GO:0033047 28 0.019
establishment of protein localization GO:0045184 163 0.019
forebrain development GO:0030900 2 0.019
eggshell formation GO:0030703 105 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
atp metabolic process GO:0046034 49 0.019
regulation of response to stress GO:0080134 200 0.019
regulation of mrna processing GO:0050684 71 0.018
protein processing GO:0016485 68 0.018
growth GO:0040007 359 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.018
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.018
Yeast
cell migration GO:0016477 238 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
chemotaxis GO:0006935 249 0.018
protein dna complex assembly GO:0065004 63 0.018
Yeast
negative regulation of proteolysis GO:0045861 31 0.018
positive regulation of cell communication GO:0010647 250 0.018
ras protein signal transduction GO:0007265 88 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
protein maturation GO:0051604 71 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
Yeast
homeostatic process GO:0042592 199 0.017
regulation of organelle organization GO:0033043 196 0.017
molting cycle GO:0042303 56 0.016
chromosome segregation GO:0007059 157 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
organic substance transport GO:0071702 257 0.016
response to oxygen containing compound GO:1901700 200 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
compound eye development GO:0048749 307 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
axonogenesis GO:0007409 290 0.016
purine containing compound metabolic process GO:0072521 155 0.015
lateral inhibition GO:0046331 206 0.015
anatomical structure homeostasis GO:0060249 97 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
digestive tract development GO:0048565 149 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
appendage morphogenesis GO:0035107 397 0.015
response to organonitrogen compound GO:0010243 75 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
regulation of cell death GO:0010941 173 0.014
snrna metabolic process GO:0016073 14 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
protein secretion GO:0009306 45 0.014
eye photoreceptor cell development GO:0042462 81 0.014
embryonic morphogenesis GO:0048598 206 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
positive regulation of protein catabolic process GO:0045732 34 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.013
negative regulation of cell cycle GO:0045786 116 0.013
regulation of ras gtpase activity GO:0032318 38 0.013
negative regulation of neuron death GO:1901215 18 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
compound eye morphogenesis GO:0001745 249 0.013
negative regulation of developmental process GO:0051093 201 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
Yeast
reproductive behavior GO:0019098 122 0.013
cellular carbohydrate metabolic process GO:0044262 22 0.013
rna catabolic process GO:0006401 37 0.013
regulation of neurogenesis GO:0050767 158 0.013
protein modification by small protein removal GO:0070646 28 0.013
recombinational repair GO:0000725 13 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
sensory organ morphogenesis GO:0090596 260 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
Yeast
regulation of phosphorus metabolic process GO:0051174 210 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
response to nitrogen compound GO:1901698 90 0.012
double strand break repair GO:0006302 26 0.012
regulation of innate immune response GO:0045088 71 0.011
negative regulation of nervous system development GO:0051961 92 0.011
small molecule metabolic process GO:0044281 305 0.011
protein modification process GO:0036211 438 0.011
multi organism reproductive behavior GO:0044705 121 0.011
photoreceptor cell development GO:0042461 96 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of dna templated transcription elongation GO:0032784 17 0.011
Yeast
negative regulation of cellular component organization GO:0051129 108 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
synaptic transmission GO:0007268 288 0.011
regulation of sister chromatid segregation GO:0033045 28 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
cellular homeostasis GO:0019725 80 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
regulation of meiosis GO:0040020 3 0.011
regulation of protein complex assembly GO:0043254 42 0.011
Yeast
epithelial cell differentiation GO:0030855 322 0.011
regulation of protein metabolic process GO:0051246 256 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.010
taxis GO:0042330 304 0.010
mrna processing GO:0006397 104 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
regulation of cellular response to stress GO:0080135 89 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
microtubule organizing center organization GO:0031023 168 0.010

Rpt4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org