Drosophila melanogaster

98 known processes

mip130 (Dmel_CG3480)

Myb-interacting protein 130

(Aliases: Dmel\CG3480,TWIT,EG:86E4.4,86E4.4,Twit,CG3480,twit,Mip130,Mip130/TWIT)

mip130 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.465
nucleosome organization GO:0034728 59 0.359
dna metabolic process GO:0006259 227 0.333
intracellular signal transduction GO:0035556 300 0.256
cell motility GO:0048870 251 0.241
response to abiotic stimulus GO:0009628 341 0.234
regulation of gene expression epigenetic GO:0040029 128 0.233
tissue morphogenesis GO:0048729 297 0.199
gene silencing GO:0016458 138 0.188
regulation of cellular ketone metabolic process GO:0010565 3 0.188
secretion by cell GO:0032940 101 0.187
larval development GO:0002164 104 0.181
Worm
phosphorylation GO:0016310 294 0.170
cytokinesis GO:0000910 90 0.168
regulation of organelle organization GO:0033043 196 0.163
cellular response to dna damage stimulus GO:0006974 223 0.157
single organism biosynthetic process GO:0044711 206 0.148
regulation of cell death GO:0010941 173 0.146
dendrite morphogenesis GO:0048813 199 0.143
positive regulation of developmental process GO:0051094 143 0.136
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.135
cell migration GO:0016477 238 0.129
death GO:0016265 284 0.127
cell proliferation GO:0008283 299 0.123
establishment of localization in cell GO:0051649 402 0.122
negative regulation of biosynthetic process GO:0009890 277 0.120
regulation of cellular amino acid metabolic process GO:0006521 0 0.119
dorsal ventral pattern formation GO:0009953 133 0.117
regulation of localization GO:0032879 275 0.116
mitotic dna integrity checkpoint GO:0044774 75 0.115
regulation of cell differentiation GO:0045595 302 0.114
regulation of multi organism process GO:0043900 131 0.104
protein dna complex subunit organization GO:0071824 86 0.103
gene silencing by rna GO:0031047 57 0.102
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.101
organic acid metabolic process GO:0006082 103 0.101
cellular macromolecular complex assembly GO:0034622 153 0.096
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.095
response to external biotic stimulus GO:0043207 293 0.093
internal protein amino acid acetylation GO:0006475 38 0.092
positive regulation of nurse cell apoptotic process GO:0045850 5 0.090
regulation of dna metabolic process GO:0051052 34 0.090
programmed cell death GO:0012501 257 0.089
cellular protein modification process GO:0006464 438 0.088
positive regulation of multicellular organismal process GO:0051240 143 0.087
mapk cascade GO:0000165 107 0.087
regulation of mitotic cell cycle GO:0007346 190 0.086
apoptotic signaling pathway GO:0097190 27 0.082
negative regulation of mitotic cell cycle GO:0045930 109 0.078
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.076
regulation of mapk cascade GO:0043408 92 0.075
regulation of cell cycle GO:0051726 291 0.075
mesenchymal cell differentiation GO:0048762 1 0.075
positive regulation of programmed cell death GO:0043068 62 0.073
ras protein signal transduction GO:0007265 88 0.071
dna conformation change GO:0071103 105 0.070
glycosyl compound catabolic process GO:1901658 112 0.070
response to oxygen containing compound GO:1901700 200 0.069
actin cytoskeleton organization GO:0030036 206 0.068
negative regulation of signaling GO:0023057 219 0.067
macromolecular complex assembly GO:0065003 256 0.066
chromatin organization GO:0006325 207 0.066
rna interference GO:0016246 27 0.066
mrna metabolic process GO:0016071 124 0.065
oxoacid metabolic process GO:0043436 103 0.065
regulation of programmed cell death GO:0043067 152 0.064
organelle fission GO:0048285 340 0.064
cell cycle dna replication GO:0044786 23 0.062
regulation of nurse cell apoptotic process GO:0045477 9 0.062
photoreceptor cell differentiation GO:0046530 170 0.062
posttranscriptional gene silencing GO:0016441 46 0.061
organic substance transport GO:0071702 257 0.061
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.061
anterior posterior pattern specification GO:0009952 136 0.060
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.060
negative regulation of gene expression GO:0010629 387 0.060
response to other organism GO:0051707 293 0.060
peptidyl amino acid modification GO:0018193 105 0.060
body morphogenesis GO:0010171 2 0.058
Worm
regulation of response to dna damage stimulus GO:2001020 23 0.058
protein localization GO:0008104 284 0.058
head development GO:0060322 135 0.057
negative regulation of response to stimulus GO:0048585 258 0.057
regulation of cellular amine metabolic process GO:0033238 3 0.057
positive regulation of rna metabolic process GO:0051254 271 0.056
protein modification process GO:0036211 438 0.056
cell death GO:0008219 279 0.055
purine containing compound metabolic process GO:0072521 155 0.055
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
cellular ketone metabolic process GO:0042180 24 0.054
regulation of phosphate metabolic process GO:0019220 210 0.052
negative regulation of cellular biosynthetic process GO:0031327 277 0.051
positive regulation of signaling GO:0023056 243 0.051
apoptotic process GO:0006915 159 0.050
determination of adult lifespan GO:0008340 137 0.050
chromatin remodeling GO:0006338 72 0.050
cellular amine metabolic process GO:0044106 12 0.050
protein acetylation GO:0006473 39 0.050
regulation of reproductive process GO:2000241 54 0.050
dorsal ventral axis specification GO:0009950 66 0.048
secretion GO:0046903 109 0.048
amine metabolic process GO:0009308 12 0.047
regulation of cellular response to stress GO:0080135 89 0.045
positive regulation of molecular function GO:0044093 136 0.045
positive regulation of signal transduction GO:0009967 223 0.045
histone modification GO:0016570 106 0.044
regulation of phosphorus metabolic process GO:0051174 210 0.044
regulation of molecular function GO:0065009 217 0.044
purine nucleotide catabolic process GO:0006195 109 0.043
regulation of cell cycle process GO:0010564 181 0.043
purine ribonucleotide catabolic process GO:0009154 109 0.042
localization of cell GO:0051674 257 0.042
reproductive system development GO:0061458 74 0.042
Worm
regulation of sister chromatid cohesion GO:0007063 2 0.041
ribonucleotide catabolic process GO:0009261 109 0.041
cellular response to endogenous stimulus GO:0071495 80 0.041
purine ribonucleotide metabolic process GO:0009150 145 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.040
positive regulation of cell communication GO:0010647 250 0.040
aromatic compound catabolic process GO:0019439 166 0.040
regulation of apoptotic process GO:0042981 130 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.037
brain development GO:0007420 120 0.037
negative regulation of rna metabolic process GO:0051253 251 0.037
negative regulation of cell communication GO:0010648 223 0.037
phagocytosis GO:0006909 215 0.036
cardiovascular system development GO:0072358 82 0.036
positive regulation of gene expression GO:0010628 290 0.036
regulation of ras protein signal transduction GO:0046578 93 0.036
small gtpase mediated signal transduction GO:0007264 88 0.036
organonitrogen compound metabolic process GO:1901564 318 0.035
muscle tissue development GO:0060537 30 0.034
carbohydrate derivative catabolic process GO:1901136 118 0.034
single organism behavior GO:0044708 391 0.034
development of primary sexual characteristics GO:0045137 50 0.034
Worm
regulation of cellular component biogenesis GO:0044087 201 0.034
central nervous system development GO:0007417 201 0.034
gonad development GO:0008406 50 0.033
Worm
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
establishment of protein localization GO:0045184 163 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
macromolecule methylation GO:0043414 45 0.033
regulation of gene silencing GO:0060968 63 0.033
single organism intracellular transport GO:1902582 207 0.033
response to temperature stimulus GO:0009266 106 0.033
exocrine system development GO:0035272 162 0.033
positive regulation of growth GO:0045927 75 0.032
regulation of protein complex assembly GO:0043254 42 0.032
purine nucleoside catabolic process GO:0006152 112 0.032
reproductive behavior GO:0019098 122 0.032
multi multicellular organism process GO:0044706 123 0.032
regulation of intracellular signal transduction GO:1902531 236 0.032
growth GO:0040007 359 0.032
positive regulation of developmental growth GO:0048639 62 0.032
regulation of neuron differentiation GO:0045664 103 0.032
cellular protein localization GO:0034613 160 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
peptidyl tyrosine modification GO:0018212 24 0.031
cellular response to organic substance GO:0071310 132 0.031
ribonucleotide metabolic process GO:0009259 145 0.030
stem cell differentiation GO:0048863 117 0.030
posttranscriptional gene silencing by rna GO:0035194 45 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.029
regulation of cellular localization GO:0060341 136 0.029
cell division GO:0051301 248 0.029
embryonic morphogenesis GO:0048598 206 0.028
erk1 and erk2 cascade GO:0070371 39 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.027
protein complex assembly GO:0006461 200 0.027
reproductive structure development GO:0048608 74 0.027
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.027
regulation of multicellular organismal development GO:2000026 414 0.027
Worm
protein dna complex assembly GO:0065004 63 0.027
response to biotic stimulus GO:0009607 294 0.027
small molecule metabolic process GO:0044281 305 0.027
response to endogenous stimulus GO:0009719 119 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
regulation of response to stress GO:0080134 200 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
mrna processing GO:0006397 104 0.026
dna biosynthetic process GO:0071897 24 0.026
covalent chromatin modification GO:0016569 106 0.026
organic substance catabolic process GO:1901575 308 0.026
internal peptidyl lysine acetylation GO:0018393 38 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.025
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.025
regulation of kinase activity GO:0043549 53 0.025
oocyte dorsal ventral axis specification GO:0007310 34 0.025
anatomical structure homeostasis GO:0060249 97 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.025
immune system process GO:0002376 347 0.024
segmentation GO:0035282 207 0.024
compound eye photoreceptor cell differentiation GO:0001751 140 0.024
response to nitrogen compound GO:1901698 90 0.024
negative regulation of signal transduction GO:0009968 206 0.024
defense response to other organism GO:0098542 225 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
positive regulation of phosphorylation GO:0042327 87 0.024
chromatin modification GO:0016568 147 0.023
tube morphogenesis GO:0035239 191 0.023
positive regulation of multicellular organism growth GO:0040018 21 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
regulation of cell cycle g1 s phase transition GO:1902806 23 0.023
regulation of meiosis GO:0040020 3 0.023
dna packaging GO:0006323 91 0.023
eye development GO:0001654 323 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
positive regulation of mapk cascade GO:0043410 63 0.023
dna integrity checkpoint GO:0031570 81 0.022
sensory organ morphogenesis GO:0090596 260 0.022
blastoderm segmentation GO:0007350 159 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
methylation GO:0032259 47 0.021
positive regulation of cell development GO:0010720 61 0.021
rac protein signal transduction GO:0016601 3 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
regulation of mrna splicing via spliceosome GO:0048024 64 0.021
rna processing GO:0006396 147 0.021
peptidyl lysine acetylation GO:0018394 39 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
negative regulation of cell cycle process GO:0010948 109 0.020
multicellular organismal reproductive behavior GO:0033057 110 0.020
regulation of transport GO:0051049 181 0.020
spermatogenesis GO:0007283 200 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
nitrogen compound transport GO:0071705 85 0.020
regulation of catalytic activity GO:0050790 185 0.020
actin filament based process GO:0030029 220 0.020
cytoplasmic transport GO:0016482 130 0.020
mitotic g2 m transition checkpoint GO:0044818 70 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.020
regulation of phosphorylation GO:0042325 147 0.020
chromatin assembly GO:0031497 48 0.019
positive regulation of apoptotic process GO:0043065 47 0.019
regulation of protein modification process GO:0031399 112 0.019
nucleoside catabolic process GO:0009164 112 0.019
developmental programmed cell death GO:0010623 138 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.018
mesenchymal cell development GO:0014031 1 0.018
homeostatic process GO:0042592 199 0.018
intracellular protein transport GO:0006886 104 0.018
dna endoreduplication GO:0042023 22 0.018
regulation of protein localization GO:0032880 76 0.018
nucleoside metabolic process GO:0009116 127 0.018
epithelial cell differentiation GO:0030855 322 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
forebrain development GO:0030900 2 0.018
epithelial cell development GO:0002064 274 0.018
telencephalon development GO:0021537 2 0.017
response to radiation GO:0009314 155 0.017
multicellular organismal aging GO:0010259 140 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
rna 3 end processing GO:0031123 45 0.017
negative regulation of chromatin silencing GO:0031936 9 0.017
sex differentiation GO:0007548 81 0.017
Worm
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
developmental growth GO:0048589 280 0.017
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
vesicle mediated transport GO:0016192 381 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
response to organic substance GO:0010033 284 0.016
regulation of immune system process GO:0002682 176 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
stem cell development GO:0048864 79 0.016
salivary gland development GO:0007431 162 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
heterocycle catabolic process GO:0046700 166 0.016
tissue death GO:0016271 102 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
leg disc development GO:0035218 92 0.016
organophosphate metabolic process GO:0019637 195 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
dendrite development GO:0016358 204 0.016
positive regulation of cell death GO:0010942 69 0.016
positive regulation of protein modification process GO:0031401 58 0.016
histone acetylation GO:0016573 38 0.015
genitalia development GO:0048806 26 0.015
Worm
intracellular transport GO:0046907 228 0.015
kidney development GO:0001822 3 0.015
telomere maintenance GO:0000723 21 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
regulation of cell development GO:0060284 215 0.015
histolysis GO:0007559 102 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
protein targeting GO:0006605 64 0.015
compound eye morphogenesis GO:0001745 249 0.015
chromosome segregation GO:0007059 157 0.015
cellular macromolecule localization GO:0070727 220 0.015
regulation of dna replication GO:0006275 13 0.015
ovarian follicle cell development GO:0030707 248 0.014
gland development GO:0048732 191 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.014
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.014
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
regulation of canonical wnt signaling pathway GO:0060828 15 0.014
rna localization GO:0006403 115 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
mitotic cell cycle phase transition GO:0044772 138 0.013
nuclear transport GO:0051169 72 0.013
response to glucose GO:0009749 2 0.013
aging GO:0007568 143 0.013
axis specification GO:0009798 167 0.013
protein localization to organelle GO:0033365 82 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
Worm
intrinsic apoptotic signaling pathway GO:0097193 16 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
cell fate specification GO:0001708 71 0.013
meiotic cell cycle GO:0051321 171 0.013
peptidyl lysine modification GO:0018205 57 0.013
regulation of transferase activity GO:0051338 58 0.013
multi organism behavior GO:0051705 175 0.013
cellular response to reactive oxygen species GO:0034614 14 0.013
regulation of nuclear division GO:0051783 58 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
regulation of erk1 and erk2 cascade GO:0070372 39 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
actin filament organization GO:0007015 126 0.012
regulation of cell proliferation GO:0042127 163 0.012
nuclear division GO:0000280 332 0.012
regulation of gtp catabolic process GO:0033124 44 0.012
regulation of chromosome organization GO:0033044 64 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
eye morphogenesis GO:0048592 260 0.012
positive regulation of cell cycle g2 m phase transition GO:1902751 2 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
regulation of intracellular transport GO:0032386 64 0.012
organophosphate catabolic process GO:0046434 112 0.012
embryonic organ development GO:0048568 50 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
circulatory system development GO:0072359 82 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
golgi organization GO:0007030 66 0.011
compound eye development GO:0048749 307 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
cation transport GO:0006812 110 0.011
endocytosis GO:0006897 310 0.011
regulation of lipid kinase activity GO:0043550 2 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
striated muscle tissue development GO:0014706 27 0.011
tube development GO:0035295 244 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
positive regulation of nervous system development GO:0051962 69 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
muscle structure development GO:0061061 224 0.011
gland morphogenesis GO:0022612 145 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.011
multi organism reproductive behavior GO:0044705 121 0.011
regulation of phosphatase activity GO:0010921 3 0.011
response to oxygen levels GO:0070482 59 0.011
nucleotide catabolic process GO:0009166 109 0.011
regulation of synaptic vesicle exocytosis GO:2000300 3 0.010
salivary gland morphogenesis GO:0007435 145 0.010
response to heat GO:0009408 63 0.010
regulation of cell division GO:0051302 72 0.010
transmembrane transport GO:0055085 139 0.010
positive regulation of cell proliferation GO:0008284 47 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
cell cycle phase transition GO:0044770 140 0.010

mip130 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
disease of anatomical entity DOID:7 0 0.021
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017