Drosophila melanogaster

214 known processes

vas (Dmel_CG3506)

vasa

(Aliases: EP(2)0812,Vasa,VASA,CG3506,BG:DS00929.14,Dmel\CG3506,pf7,Vas,fs(2)ltoRJ36,VAS,DmRH25,cgt)

vas biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chorion containing eggshell formation GO:0007304 105 0.999
oocyte differentiation GO:0009994 145 0.998
meiotic cell cycle GO:0051321 171 0.995
regulation of pole plasm oskar mrna localization GO:0007317 27 0.994
eggshell formation GO:0030703 105 0.993
dorsal appendage formation GO:0046843 47 0.993
pole plasm protein localization GO:0007318 10 0.992
ovarian follicle cell development GO:0030707 248 0.992
oocyte anterior posterior axis specification GO:0007314 72 0.991
germarium derived egg chamber formation GO:0007293 101 0.991
eggshell chorion assembly GO:0007306 66 0.989
meiotic nuclear division GO:0007126 151 0.989
nuclear division GO:0000280 332 0.987
pole plasm assembly GO:0007315 61 0.985
regionalization GO:0003002 416 0.985
germarium derived oocyte fate determination GO:0007294 26 0.983
oocyte development GO:0048599 124 0.970
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.967
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.966
regulation of oocyte development GO:0060281 27 0.963
meiotic cell cycle process GO:1903046 132 0.954
oocyte construction GO:0007308 112 0.951
epithelial cell differentiation GO:0030855 322 0.937
oocyte axis specification GO:0007309 108 0.934
axis specification GO:0009798 167 0.924
meiosis i GO:0007127 59 0.909
Mouse
pole plasm rna localization GO:0007316 52 0.907
columnar cuboidal epithelial cell development GO:0002066 249 0.895
negative regulation of rna biosynthetic process GO:1902679 240 0.888
blastoderm segmentation GO:0007350 159 0.880
oocyte microtubule cytoskeleton organization GO:0016325 35 0.869
pole plasm mrna localization GO:0019094 49 0.868
cell maturation GO:0048469 144 0.857
pole plasm oskar mrna localization GO:0045451 46 0.849
intracellular mrna localization GO:0008298 66 0.846
segmentation GO:0035282 207 0.843
anterior posterior axis specification GO:0009948 109 0.842
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.840
organelle fission GO:0048285 340 0.833
germ line stem cell division GO:0042078 25 0.831
maternal determination of anterior posterior axis embryo GO:0008358 74 0.807
germ line stem cell maintenance GO:0030718 50 0.796
cytoplasm organization GO:0007028 64 0.795
negative regulation of cellular metabolic process GO:0031324 382 0.786
positive regulation of cellular biosynthetic process GO:0031328 316 0.739
chromosome organization GO:0051276 360 0.721
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.721
ovarian fusome organization GO:0030723 11 0.707
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.698
developmental maturation GO:0021700 172 0.694
negative regulation of biosynthetic process GO:0009890 277 0.686
male meiosis GO:0007140 52 0.673
Mouse
polarity specification of anterior posterior axis GO:0009949 5 0.666
negative regulation of rna metabolic process GO:0051253 251 0.663
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.661
gene silencing GO:0016458 138 0.650
Worm
oocyte maturation GO:0001556 3 0.633
negative regulation of gene expression GO:0010629 387 0.618
Worm
ribonucleoprotein complex subunit organization GO:0071826 28 0.584
embryonic pattern specification GO:0009880 174 0.582
germarium derived oocyte differentiation GO:0030706 29 0.573
anterior posterior pattern specification GO:0009952 136 0.568
long term memory GO:0007616 62 0.557
stem cell maintenance GO:0019827 67 0.557
karyosome formation GO:0030717 22 0.553
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.552
oocyte dorsal ventral axis specification GO:0007310 34 0.541
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.506
embryonic axis specification GO:0000578 107 0.502
female meiotic division GO:0007143 70 0.471
cell division GO:0051301 248 0.456
negative regulation of nucleic acid templated transcription GO:1903507 240 0.451
spermatogenesis GO:0007283 200 0.446
Mouse
female germ line stem cell asymmetric division GO:0048132 14 0.445
ribonucleoprotein complex biogenesis GO:0022613 31 0.437
positive regulation of biosynthetic process GO:0009891 316 0.409
regulation of gene expression epigenetic GO:0040029 128 0.405
Worm
chromosome segregation GO:0007059 157 0.398
heterochromatin organization GO:0070828 25 0.393
negative regulation of cellular biosynthetic process GO:0031327 277 0.379
regulation of meiosis GO:0040020 3 0.371
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.360
stem cell division GO:0017145 69 0.359
localization of cell GO:0051674 257 0.352
chromatin silencing GO:0006342 76 0.344
rna localization GO:0006403 115 0.333
chromosome condensation GO:0030261 41 0.332
germline stem cell asymmetric division GO:0098728 15 0.329
pole cell development GO:0007277 26 0.327
regulation of reproductive process GO:2000241 54 0.323
dna conformation change GO:0071103 105 0.318
dorsal ventral pattern formation GO:0009953 133 0.305
gland development GO:0048732 191 0.288
negative regulation of transcription dna templated GO:0045892 237 0.283
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.278
cystoblast division GO:0007282 10 0.278
cell migration GO:0016477 238 0.264
positive regulation of rna metabolic process GO:0051254 271 0.260
regulation of embryonic development GO:0045995 68 0.255
epithelial cell development GO:0002064 274 0.250
male gamete generation GO:0048232 201 0.250
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.242
negative regulation of gene expression epigenetic GO:0045814 77 0.237
pole cell formation GO:0007279 19 0.235
cell motility GO:0048870 251 0.235
fertilization GO:0009566 26 0.234
cell fate determination GO:0001709 91 0.230
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.227
tripartite regional subdivision GO:0007351 103 0.223
cell death GO:0008219 279 0.220
Worm
epithelial cell migration GO:0010631 148 0.219
catabolic process GO:0009056 409 0.213
negative regulation of protein complex disassembly GO:0043242 23 0.212
dna metabolic process GO:0006259 227 0.211
tube morphogenesis GO:0035239 191 0.207
positive regulation of gene expression GO:0010628 290 0.205
tissue morphogenesis GO:0048729 297 0.203
embryonic morphogenesis GO:0048598 206 0.193
cellular component assembly involved in morphogenesis GO:0010927 151 0.189
cellular response to organic substance GO:0071310 132 0.186
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.183
learning or memory GO:0007611 141 0.182
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.174
developmental programmed cell death GO:0010623 138 0.173
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.171
negative regulation of cellular component organization GO:0051129 108 0.170
regulation of cell maturation GO:1903429 27 0.170
meiotic chromosome segregation GO:0045132 59 0.168
regulation of organelle organization GO:0033043 196 0.165
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.163
morphogenesis of follicular epithelium GO:0016333 36 0.161
regulation of mrna processing GO:0050684 71 0.160
stem cell development GO:0048864 79 0.159
nuclear import GO:0051170 51 0.158
oocyte fate determination GO:0030716 27 0.157
regulation of multi organism process GO:0043900 131 0.157
negative regulation of developmental process GO:0051093 201 0.152
posttranscriptional gene silencing by rna GO:0035194 45 0.148
Worm
single organism cellular localization GO:1902580 180 0.143
protein localization GO:0008104 284 0.139
regulation of cellular protein metabolic process GO:0032268 243 0.137
nuclear migration GO:0007097 20 0.133
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.127
mrna processing GO:0006397 104 0.124
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.120
digestive tract morphogenesis GO:0048546 127 0.116
chorion containing eggshell pattern formation GO:0030381 11 0.114
regulation of cell cycle process GO:0010564 181 0.113
dorsal ventral axis specification GO:0009950 66 0.112
transcription from rna polymerase ii promoter GO:0006366 368 0.106
positive regulation of transcription dna templated GO:0045893 266 0.104
nucleus localization GO:0051647 34 0.102
regulation of embryonic pattern specification GO:1902875 27 0.097
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.097
gene silencing by rna GO:0031047 57 0.095
Worm
hindgut development GO:0061525 58 0.095
rna interference GO:0016246 27 0.095
Worm
rna processing GO:0006396 147 0.094
programmed cell death GO:0012501 257 0.094
Worm
dna methylation GO:0006306 4 0.093
cellularization GO:0007349 90 0.092
meiotic chromosome condensation GO:0010032 3 0.091
cytokinesis GO:0000910 90 0.087
gastrulation GO:0007369 70 0.086
cellular response to organic cyclic compound GO:0071407 32 0.086
germ cell migration GO:0008354 43 0.085
negative regulation of cell differentiation GO:0045596 143 0.085
actin filament based process GO:0030029 220 0.085
regulation of cell size GO:0008361 63 0.084
specification of axis polarity GO:0065001 6 0.084
immune response GO:0006955 246 0.084
dna packaging GO:0006323 91 0.083
chromatin organization GO:0006325 207 0.081
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.081
negative regulation of transposition GO:0010529 12 0.077
cellular macromolecule localization GO:0070727 220 0.077
positive regulation of cellular protein metabolic process GO:0032270 118 0.076
cellular nitrogen compound catabolic process GO:0044270 165 0.076
mitotic nuclear division GO:0007067 213 0.075
mrna catabolic process GO:0006402 33 0.075
defense response to other organism GO:0098542 225 0.074
aromatic compound catabolic process GO:0019439 166 0.074
regulation of meiotic cell cycle GO:0051445 9 0.074
anterior posterior axis specification embryo GO:0008595 103 0.073
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.073
regulation of nuclear division GO:0051783 58 0.071
sister chromatid segregation GO:0000819 92 0.070
meiotic cytokinesis GO:0033206 33 0.069
female germ line stem cell maintenance GO:0036099 8 0.069
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.066
mitotic chromosome condensation GO:0007076 22 0.064
regulation of protein metabolic process GO:0051246 256 0.064
border follicle cell migration GO:0007298 113 0.062
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.061
posttranscriptional gene silencing GO:0016441 46 0.061
Worm
dna recombination GO:0006310 32 0.060
nucleus organization GO:0006997 45 0.060
male pronucleus assembly GO:0035039 6 0.058
intracellular transport GO:0046907 228 0.058
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.057
regulation of cell division GO:0051302 72 0.057
exocrine system development GO:0035272 162 0.057
regulation of anatomical structure morphogenesis GO:0022603 242 0.057
histolysis GO:0007559 102 0.056
single fertilization GO:0007338 24 0.056
dna alkylation GO:0006305 4 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.056
locomotory behavior GO:0007626 176 0.055
embryonic cleavage GO:0040016 5 0.054
positive regulation of cell cycle GO:0045787 43 0.054
organic cyclic compound catabolic process GO:1901361 168 0.054
regulation of protein complex disassembly GO:0043244 29 0.053
regulation of cellular catabolic process GO:0031329 157 0.052
positive regulation of cell cycle process GO:0090068 28 0.051
positive regulation of nucleic acid templated transcription GO:1903508 266 0.050
response to light stimulus GO:0009416 124 0.050
germarium derived female germ line cyst encapsulation GO:0030708 8 0.050
cellular ketone metabolic process GO:0042180 24 0.049
negative regulation of mitotic cell cycle GO:0045930 109 0.049
tissue death GO:0016271 102 0.049
regulation of cellular localization GO:0060341 136 0.047
taxis GO:0042330 304 0.047
cell cycle dna replication GO:0044786 23 0.047
positive regulation of mrna catabolic process GO:0061014 5 0.045
response to biotic stimulus GO:0009607 294 0.044
defense response to bacterium GO:0042742 178 0.044
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.044
pronuclear migration GO:0035046 4 0.044
regulation of mitotic cell cycle GO:0007346 190 0.042
ovarian follicle cell migration GO:0007297 121 0.042
regulation of immune system process GO:0002682 176 0.042
fusome organization GO:0045478 13 0.042
regulation of cellular component biogenesis GO:0044087 201 0.041
production of small rna involved in gene silencing by rna GO:0070918 15 0.041
digestive tract development GO:0048565 149 0.040
salivary gland development GO:0007431 162 0.040
organic substance catabolic process GO:1901575 308 0.040
morphogenesis of an epithelium GO:0002009 276 0.040
compound eye morphogenesis GO:0001745 249 0.039
cellular response to chemical stimulus GO:0070887 199 0.039
protein modification process GO:0036211 438 0.039
positive regulation of phosphorus metabolic process GO:0010562 139 0.038
eye antennal disc development GO:0035214 60 0.038
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.038
dendrite morphogenesis GO:0048813 199 0.037
carboxylic acid metabolic process GO:0019752 92 0.037
death GO:0016265 284 0.037
Worm
salivary gland morphogenesis GO:0007435 145 0.037
regulation of cell cycle GO:0051726 291 0.037
negative regulation of dna metabolic process GO:0051053 12 0.036
regulation of catabolic process GO:0009894 170 0.036
stem cell differentiation GO:0048863 117 0.036
regulation of cellular amine metabolic process GO:0033238 3 0.036
tissue migration GO:0090130 155 0.036
dna methylation or demethylation GO:0044728 4 0.035
establishment of nucleus localization GO:0040023 26 0.035
meiotic spindle organization GO:0000212 36 0.035
mitotic cell cycle embryonic GO:0045448 38 0.035
ameboidal type cell migration GO:0001667 151 0.034
rna catabolic process GO:0006401 37 0.034
compound eye development GO:0048749 307 0.034
response to abiotic stimulus GO:0009628 341 0.034
embryo development ending in birth or egg hatching GO:0009792 152 0.033
organelle assembly GO:0070925 198 0.033
cellular response to dsrna GO:0071359 15 0.033
regulation of mrna 3 end processing GO:0031440 7 0.033
apoptotic process GO:0006915 159 0.033
Worm
negative regulation of organelle organization GO:0010639 56 0.032
regulation of cellular ketone metabolic process GO:0010565 3 0.032
regulation of anatomical structure size GO:0090066 163 0.032
salivary gland histolysis GO:0035070 88 0.031
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.031
gland morphogenesis GO:0022612 145 0.031
innate immune response GO:0045087 144 0.030
microtubule organizing center organization GO:0031023 168 0.030
immune system process GO:0002376 347 0.030
endocytosis GO:0006897 310 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
regulation of oskar mrna translation GO:0046011 8 0.028
negative regulation of response to stimulus GO:0048585 258 0.027
single organism behavior GO:0044708 391 0.027
response to other organism GO:0051707 293 0.027
ribonucleoprotein complex assembly GO:0022618 23 0.027
regulation of multicellular organismal development GO:2000026 414 0.027
regulation of cell differentiation GO:0045595 302 0.027
cognition GO:0050890 141 0.026
nephron epithelium morphogenesis GO:0072088 3 0.026
positive regulation of molecular function GO:0044093 136 0.026
meiosis ii GO:0007135 23 0.026
chromatin assembly or disassembly GO:0006333 52 0.025
cell proliferation GO:0008283 299 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.025
methylation GO:0032259 47 0.025
dsrna fragmentation GO:0031050 15 0.025
regulation of epithelial cell differentiation GO:0030856 4 0.025
heterocycle catabolic process GO:0046700 166 0.025
negative regulation of protein depolymerization GO:1901880 23 0.025
defense response to gram negative bacterium GO:0050829 94 0.025
regulation of immune response GO:0050776 118 0.024
synaptic transmission GO:0007268 288 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
hindgut morphogenesis GO:0007442 58 0.024
germ line cyst encapsulation GO:0048138 8 0.024
digestive system development GO:0055123 149 0.024
negative regulation of microtubule depolymerization GO:0007026 21 0.024
cytoplasmic transport GO:0016482 130 0.024
positive regulation of cellular catabolic process GO:0031331 95 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
spindle organization GO:0007051 253 0.023
female germ line cyst formation GO:0048135 42 0.023
maintenance of location in cell GO:0051651 28 0.022
cellular component disassembly GO:0022411 46 0.022
chromosome organization involved in meiosis GO:0070192 10 0.022
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.022
germarium derived female germ line cyst formation GO:0030727 42 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
anatomical structure homeostasis GO:0060249 97 0.021
retina development in camera type eye GO:0060041 4 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
regulation of protein depolymerization GO:1901879 27 0.021
negative regulation of cellular catabolic process GO:0031330 34 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
response to organic cyclic compound GO:0014070 89 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
establishment of localization in cell GO:0051649 402 0.020
actin cytoskeleton organization GO:0030036 206 0.020
response to bacterium GO:0009617 198 0.020
chromatin modification GO:0016568 147 0.020
positive regulation of cell communication GO:0010647 250 0.020
positive regulation of hydrolase activity GO:0051345 78 0.019
reproductive system development GO:0061458 74 0.019
Zebrafish
positive regulation of catalytic activity GO:0043085 118 0.019
positive regulation of signal transduction GO:0009967 223 0.019
mitotic spindle stabilization GO:0043148 6 0.019
regulation of cell morphogenesis GO:0022604 163 0.019
phosphorylation GO:0016310 294 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of translation GO:0045727 12 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
apical constriction GO:0003383 18 0.018
response to radiation GO:0009314 155 0.018
positive regulation of organelle organization GO:0010638 65 0.018
response to ecdysone GO:0035075 34 0.017
cellular protein modification process GO:0006464 438 0.017
response to decreased oxygen levels GO:0036293 58 0.017
regulation of mrna catabolic process GO:0061013 5 0.017
negative regulation of meiotic cell cycle GO:0051447 2 0.017
microtubule polymerization or depolymerization GO:0031109 39 0.016
open tracheal system development GO:0007424 204 0.016
negative regulation of protein catabolic process GO:0042177 17 0.016
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.016
cytoskeleton dependent cytokinesis GO:0061640 81 0.016
spindle stabilization GO:0043146 14 0.016
regulation of protein catabolic process GO:0042176 55 0.016
response to ketone GO:1901654 34 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
defense response GO:0006952 300 0.015
response to external biotic stimulus GO:0043207 293 0.015
regulation of translation GO:0006417 56 0.015
camera type eye development GO:0043010 4 0.015
response to organic substance GO:0010033 284 0.015
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.015
peptidyl amino acid modification GO:0018193 105 0.015
developmental growth GO:0048589 280 0.015
regulation of catalytic activity GO:0050790 185 0.015
hindbrain development GO:0030902 2 0.014
mitochondrion degradation GO:0000422 8 0.014
oxoacid metabolic process GO:0043436 103 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
kidney epithelium development GO:0072073 3 0.014
ovarian follicle cell stalk formation GO:0030713 17 0.014
regulation of malpighian tubule diameter GO:0035297 3 0.013
macromolecule methylation GO:0043414 45 0.013
cellular catabolic process GO:0044248 372 0.013
spindle assembly involved in female meiosis GO:0007056 14 0.013
response to nitrogen compound GO:1901698 90 0.013
production of sirna involved in rna interference GO:0030422 11 0.013
eye development GO:0001654 323 0.013
regulation of cell development GO:0060284 215 0.013
regulation of embryonic cell shape GO:0016476 30 0.012
ectodermal placode development GO:0071696 4 0.012
negative regulation of phosphatase activity GO:0010923 3 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
positive regulation of catabolic process GO:0009896 105 0.012
protein targeting to nucleus GO:0044744 51 0.012
regulation of cellular component size GO:0032535 98 0.012
cellular response to hypoxia GO:0071456 28 0.012
regulation of tube size GO:0035150 46 0.012
establishment of protein localization GO:0045184 163 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
wound healing GO:0042060 75 0.012
actin filament organization GO:0007015 126 0.012
positive regulation of signaling GO:0023056 243 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
macromolecular complex assembly GO:0065003 256 0.011
neural precursor cell proliferation GO:0061351 75 0.011
negative regulation of cell cycle GO:0045786 116 0.011
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.011
negative regulation of cell division GO:0051782 17 0.011
covalent chromatin modification GO:0016569 106 0.011
secretion GO:0046903 109 0.011
response to wounding GO:0009611 94 0.011
establishment of tissue polarity GO:0007164 87 0.011
cytoplasmic translation GO:0002181 0 0.011
muscle structure development GO:0061061 224 0.010
regulation of multicellular organism growth GO:0040014 40 0.010
rna 3 end processing GO:0031123 45 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
negative regulation of cytoskeleton organization GO:0051494 30 0.010
positive regulation of mitotic cell cycle GO:0045931 34 0.010
single organism biosynthetic process GO:0044711 206 0.010

vas disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.081
disease of cellular proliferation DOID:14566 0 0.081
organ system cancer DOID:0050686 0 0.064
breast cancer DOID:1612 0 0.031
thoracic cancer DOID:5093 0 0.031