Drosophila melanogaster

112 known processes

schlank (Dmel_CG3576)

CG3576 gene product from transcript CG3576-RB

(Aliases: Dmel\CG3576,Dlag1,l(1)G0365,l(1)G0061,lon,Lag1,CG15898,DLag1,CG3576,DLAG1,l(1)G0489)

schlank biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.328
imaginal disc derived appendage morphogenesis GO:0035114 395 0.317
imaginal disc derived appendage development GO:0048737 399 0.289
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.212
single organism biosynthetic process GO:0044711 206 0.193
small molecule metabolic process GO:0044281 305 0.170
wing disc morphogenesis GO:0007472 344 0.151
regulation of anatomical structure morphogenesis GO:0022603 242 0.150
appendage morphogenesis GO:0035107 397 0.142
regulation of cell morphogenesis GO:0022604 163 0.139
negative regulation of cellular metabolic process GO:0031324 382 0.133
cell projection assembly GO:0030031 94 0.133
chromosome organization GO:0051276 360 0.131
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.126
cell adhesion GO:0007155 136 0.125
actin cytoskeleton organization GO:0030036 206 0.124
appendage development GO:0048736 401 0.121
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.121
epithelial cell differentiation GO:0030855 322 0.114
programmed cell death GO:0012501 257 0.114
epithelial cell development GO:0002064 274 0.113
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.109
imaginal disc fusion GO:0046528 19 0.108
organophosphate metabolic process GO:0019637 195 0.099
negative regulation of rna metabolic process GO:0051253 251 0.097
growth GO:0040007 359 0.093
ribonucleoside triphosphate catabolic process GO:0009203 108 0.092
oocyte dorsal ventral axis specification GO:0007310 34 0.091
establishment or maintenance of cell polarity GO:0007163 167 0.091
positive regulation of biosynthetic process GO:0009891 316 0.090
embryonic morphogenesis GO:0048598 206 0.087
developmental growth GO:0048589 280 0.086
purine ribonucleoside catabolic process GO:0046130 112 0.086
nucleoside metabolic process GO:0009116 127 0.084
positive regulation of multicellular organismal process GO:0051240 143 0.083
cellular catabolic process GO:0044248 372 0.081
negative regulation of gene expression GO:0010629 387 0.080
regulation of gtpase activity GO:0043087 44 0.079
actin filament based process GO:0030029 220 0.078
apoptotic process GO:0006915 159 0.078
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.078
nucleoside triphosphate metabolic process GO:0009141 120 0.076
spermatogenesis GO:0007283 200 0.076
organonitrogen compound catabolic process GO:1901565 128 0.074
biological adhesion GO:0022610 138 0.074
organic cyclic compound catabolic process GO:1901361 168 0.072
organic substance catabolic process GO:1901575 308 0.071
cell death GO:0008219 279 0.071
catabolic process GO:0009056 409 0.070
mesoderm development GO:0007498 78 0.068
sensory organ morphogenesis GO:0090596 260 0.067
columnar cuboidal epithelial cell development GO:0002066 249 0.065
guanosine containing compound metabolic process GO:1901068 74 0.065
ribose phosphate metabolic process GO:0019693 145 0.062
ribose phosphate biosynthetic process GO:0046390 28 0.062
meiotic nuclear division GO:0007126 151 0.061
regulation of tube architecture open tracheal system GO:0035152 68 0.059
regulation of multicellular organism growth GO:0040014 40 0.058
eye morphogenesis GO:0048592 260 0.058
regulation of growth GO:0040008 233 0.058
homeostatic process GO:0042592 199 0.057
positive regulation of developmental process GO:0051094 143 0.056
establishment of organelle localization GO:0051656 122 0.055
nucleoside triphosphate catabolic process GO:0009143 108 0.055
positive regulation of developmental growth GO:0048639 62 0.054
digestive tract morphogenesis GO:0048546 127 0.054
meiotic cell cycle GO:0051321 171 0.054
eye photoreceptor cell differentiation GO:0001754 145 0.054
gastrulation GO:0007369 70 0.053
ribonucleotide metabolic process GO:0009259 145 0.052
regionalization GO:0003002 416 0.052
eye development GO:0001654 323 0.051
nucleotide metabolic process GO:0009117 161 0.051
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.051
cell cell signaling involved in cell fate commitment GO:0045168 210 0.050
dorsal ventral axis specification GO:0009950 66 0.050
negative regulation of cellular biosynthetic process GO:0031327 277 0.050
ribonucleoside metabolic process GO:0009119 127 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
regulation of multicellular organismal development GO:2000026 414 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.047
photoreceptor cell differentiation GO:0046530 170 0.047
carbohydrate derivative metabolic process GO:1901135 217 0.047
heterocycle catabolic process GO:0046700 166 0.047
stem cell development GO:0048864 79 0.047
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.046
ovarian follicle cell development GO:0030707 248 0.046
positive regulation of rna biosynthetic process GO:1902680 266 0.046
positive regulation of cellular biosynthetic process GO:0031328 316 0.046
chemical homeostasis GO:0048878 92 0.045
lipid metabolic process GO:0006629 121 0.045
regulation of developmental growth GO:0048638 174 0.045
purine nucleoside metabolic process GO:0042278 127 0.044
head development GO:0060322 135 0.044
cell proliferation GO:0008283 299 0.043
negative regulation of cell proliferation GO:0008285 69 0.042
carbohydrate derivative biosynthetic process GO:1901137 85 0.041
chromosome segregation GO:0007059 157 0.040
negative regulation of cell differentiation GO:0045596 143 0.040
ribonucleoside triphosphate metabolic process GO:0009199 119 0.040
regulation of intracellular signal transduction GO:1902531 236 0.040
organonitrogen compound metabolic process GO:1901564 318 0.039
actin filament organization GO:0007015 126 0.038
regulation of apoptotic process GO:0042981 130 0.038
single organism catabolic process GO:0044712 228 0.038
regulation of localization GO:0032879 275 0.038
regulation of programmed cell death GO:0043067 152 0.037
glycosyl compound metabolic process GO:1901657 127 0.037
purine containing compound catabolic process GO:0072523 112 0.036
death GO:0016265 284 0.036
positive regulation of gene expression GO:0010628 290 0.036
regulation of purine nucleotide catabolic process GO:0033121 48 0.036
immune system process GO:0002376 347 0.036
purine nucleotide metabolic process GO:0006163 146 0.035
response to organic substance GO:0010033 284 0.035
protein modification process GO:0036211 438 0.035
negative regulation of biosynthetic process GO:0009890 277 0.035
cellular response to chemical stimulus GO:0070887 199 0.035
instar larval development GO:0002168 55 0.035
meiotic cell cycle process GO:1903046 132 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
establishment of localization in cell GO:0051649 402 0.034
cellular lipid metabolic process GO:0044255 83 0.033
lateral inhibition GO:0046331 206 0.033
negative regulation of rna biosynthetic process GO:1902679 240 0.033
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.032
ribonucleoside catabolic process GO:0042454 112 0.032
regulation of cellular localization GO:0060341 136 0.032
cellular protein modification process GO:0006464 438 0.031
regulation of transport GO:0051049 181 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
establishment of cell polarity GO:0030010 40 0.031
positive regulation of gtp catabolic process GO:0033126 43 0.031
cuticle pigmentation GO:0048067 22 0.031
localization of cell GO:0051674 257 0.031
stem cell differentiation GO:0048863 117 0.030
organelle assembly GO:0070925 198 0.030
nucleoside catabolic process GO:0009164 112 0.030
regulation of cell projection organization GO:0031344 92 0.030
nuclear division GO:0000280 332 0.030
axon cargo transport GO:0008088 29 0.030
purine ribonucleoside metabolic process GO:0046128 127 0.029
activation of cysteine type endopeptidase activity GO:0097202 17 0.029
small gtpase mediated signal transduction GO:0007264 88 0.029
cellular response to organic substance GO:0071310 132 0.029
regulation of nucleotide catabolic process GO:0030811 48 0.028
immune response GO:0006955 246 0.028
proteolysis GO:0006508 192 0.028
regulation of cell differentiation GO:0045595 302 0.028
vesicle mediated transport GO:0016192 381 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.027
nucleotide catabolic process GO:0009166 109 0.027
inorganic ion transmembrane transport GO:0098660 73 0.027
endocytosis GO:0006897 310 0.027
regulation of mitotic cell cycle GO:0007346 190 0.026
respiratory system development GO:0060541 213 0.026
cilium morphogenesis GO:0060271 39 0.026
cellular component disassembly GO:0022411 46 0.026
response to other organism GO:0051707 293 0.026
chorion containing eggshell formation GO:0007304 105 0.026
positive regulation of intracellular signal transduction GO:1902533 116 0.025
intracellular transport GO:0046907 228 0.025
regulation of intracellular transport GO:0032386 64 0.025
lamellipodium organization GO:0097581 21 0.025
axon development GO:0061564 297 0.025
regulation of cell cycle process GO:0010564 181 0.025
salivary gland morphogenesis GO:0007435 145 0.024
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.024
purine containing compound metabolic process GO:0072521 155 0.024
rrna processing GO:0006364 3 0.024
endomembrane system organization GO:0010256 119 0.024
response to wounding GO:0009611 94 0.024
positive regulation of rna metabolic process GO:0051254 271 0.023
cell motility GO:0048870 251 0.023
eggshell formation GO:0030703 105 0.023
multicellular organism growth GO:0035264 46 0.023
regulation of cell cycle GO:0051726 291 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
dna metabolic process GO:0006259 227 0.023
regulation of neuron projection development GO:0010975 69 0.023
organic substance transport GO:0071702 257 0.023
microtubule based movement GO:0007018 51 0.023
myotube cell development GO:0014904 3 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
response to abiotic stimulus GO:0009628 341 0.022
regulation of protein localization GO:0032880 76 0.022
microtubule based transport GO:0010970 42 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
sister chromatid segregation GO:0000819 92 0.022
organic acid metabolic process GO:0006082 103 0.021
mesenchymal cell differentiation GO:0048762 1 0.021
regulation of gtp catabolic process GO:0033124 44 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
positive regulation of multicellular organism growth GO:0040018 21 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
taxis GO:0042330 304 0.021
sensory perception of sound GO:0007605 56 0.021
neurological system process GO:0050877 358 0.021
tor signaling GO:0031929 32 0.021
mitotic sister chromatid segregation GO:0000070 87 0.021
ion transport GO:0006811 145 0.021
tissue morphogenesis GO:0048729 297 0.020
regulation of catabolic process GO:0009894 170 0.020
response to biotic stimulus GO:0009607 294 0.020
multi multicellular organism process GO:0044706 123 0.020
developmental maturation GO:0021700 172 0.020
response to organic cyclic compound GO:0014070 89 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
cell maturation GO:0048469 144 0.019
blastoderm segmentation GO:0007350 159 0.019
single organismal cell cell adhesion GO:0016337 45 0.019
digestive tract development GO:0048565 149 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
regulation of mitotic sister chromatid segregation GO:0033047 28 0.019
protein k48 linked ubiquitination GO:0070936 3 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
positive regulation of immune response GO:0050778 63 0.019
single organism cell adhesion GO:0098602 47 0.019
photoreceptor cell development GO:0042461 96 0.019
camera type eye development GO:0043010 4 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
open tracheal system development GO:0007424 204 0.018
establishment of mitochondrion localization GO:0051654 7 0.018
response to radiation GO:0009314 155 0.018
endosomal transport GO:0016197 44 0.018
water homeostasis GO:0030104 3 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
cellularization GO:0007349 90 0.018
transmembrane transport GO:0055085 139 0.018
salivary gland development GO:0007431 162 0.018
ras protein signal transduction GO:0007265 88 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.017
organelle localization GO:0051640 148 0.017
multicellular organismal aging GO:0010259 140 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.017
regulation of ras gtpase activity GO:0032318 38 0.017
positive regulation of nucleotide metabolic process GO:0045981 55 0.017
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.017
regulation of cell death GO:0010941 173 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.017
male gamete generation GO:0048232 201 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
regulation of hormone levels GO:0010817 40 0.017
mesenchymal cell development GO:0014031 1 0.017
mrna processing GO:0006397 104 0.017
axonogenesis GO:0007409 290 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
locomotory behavior GO:0007626 176 0.017
macromolecular complex assembly GO:0065003 256 0.016
brain development GO:0007420 120 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
establishment of vesicle localization GO:0051650 51 0.016
chromatin organization GO:0006325 207 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
regulation of cell growth GO:0001558 43 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
aging GO:0007568 143 0.016
cell migration GO:0016477 238 0.016
regulation of cell shape GO:0008360 113 0.016
nucleoside monophosphate metabolic process GO:0009123 52 0.016
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.016
macromolecule catabolic process GO:0009057 161 0.016
forebrain development GO:0030900 2 0.016
regulation of molecular function GO:0065009 217 0.015
negative regulation of cell death GO:0060548 81 0.015
ameboidal type cell migration GO:0001667 151 0.015
pigmentation GO:0043473 75 0.015
establishment of spindle localization GO:0051293 22 0.015
amino sugar metabolic process GO:0006040 10 0.015
connective tissue development GO:0061448 3 0.015
response to endoplasmic reticulum stress GO:0034976 28 0.015
mitotic cell cycle embryonic GO:0045448 38 0.015
regulation of bmp signaling pathway GO:0030510 23 0.015
positive regulation of signal transduction GO:0009967 223 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
positive regulation of transport GO:0051050 92 0.015
epithelial cell migration GO:0010631 148 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
cell growth GO:0016049 108 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.014
digestive system development GO:0055123 149 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
response to alcohol GO:0097305 95 0.014
imaginal disc derived wing vein specification GO:0007474 48 0.014
sensory perception GO:0007600 196 0.014
pigment metabolic process GO:0042440 84 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
protein localization GO:0008104 284 0.014
segmentation GO:0035282 207 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
regulation of hydrolase activity GO:0051336 97 0.014
cellular homeostasis GO:0019725 80 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
protein complex biogenesis GO:0070271 201 0.014
innate immune response GO:0045087 144 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
organelle fission GO:0048285 340 0.014
intracellular signal transduction GO:0035556 300 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
heart process GO:0003015 37 0.013
muscle structure development GO:0061061 224 0.013
ribonucleotide biosynthetic process GO:0009260 28 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
negative regulation of cell cycle GO:0045786 116 0.013
hemocyte differentiation GO:0042386 38 0.013
body morphogenesis GO:0010171 2 0.013
oocyte construction GO:0007308 112 0.013
muscle organ development GO:0007517 127 0.013
spindle organization GO:0007051 253 0.013
response to endogenous stimulus GO:0009719 119 0.013
regulation of hemocyte differentiation GO:0045610 22 0.013
cytoplasmic transport GO:0016482 130 0.013
intracellular protein transport GO:0006886 104 0.013
positive regulation of molecular function GO:0044093 136 0.013
mitochondrion distribution GO:0048311 10 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
oocyte differentiation GO:0009994 145 0.013
cellular macromolecule localization GO:0070727 220 0.013
single organism intracellular transport GO:1902582 207 0.013
compound eye morphogenesis GO:0001745 249 0.013
eye pigmentation GO:0048069 43 0.012
phagocytosis GO:0006909 215 0.012
histone modification GO:0016570 106 0.012
heart development GO:0007507 82 0.012
response to copper ion GO:0046688 4 0.012
response to monosaccharide GO:0034284 4 0.012
skeletal muscle organ development GO:0060538 48 0.012
positive regulation of cell growth GO:0030307 19 0.012
ocellus pigment metabolic process GO:0046158 19 0.012
response to external biotic stimulus GO:0043207 293 0.012
tube morphogenesis GO:0035239 191 0.012
atp metabolic process GO:0046034 49 0.012
retina development in camera type eye GO:0060041 4 0.012
rna localization GO:0006403 115 0.012
negative regulation of signal transduction GO:0009968 206 0.012
single organism cellular localization GO:1902580 180 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
humoral immune response GO:0006959 117 0.012
sterol homeostasis GO:0055092 4 0.012
gtp catabolic process GO:0006184 72 0.012
rna processing GO:0006396 147 0.012
positive regulation of nucleoside metabolic process GO:0045979 47 0.012
reproductive behavior GO:0019098 122 0.012
protein acylation GO:0043543 42 0.012
secretion GO:0046903 109 0.012
response to oxygen containing compound GO:1901700 200 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
compound eye development GO:0048749 307 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
gland development GO:0048732 191 0.012
regulation of nucleoside metabolic process GO:0009118 50 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
embryonic pattern specification GO:0009880 174 0.012
detection of stimulus GO:0051606 156 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
rhabdomere development GO:0042052 38 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of cell fate specification GO:0042659 27 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of cell communication GO:0010647 250 0.011
phosphorylation GO:0016310 294 0.011
actin cytoskeleton reorganization GO:0031532 22 0.011
single organism behavior GO:0044708 391 0.011
regulation of chromosome organization GO:0033044 64 0.011
action potential GO:0001508 13 0.011
determination of adult lifespan GO:0008340 137 0.011
molting cycle process GO:0022404 29 0.011
regulation of imaginal disc growth GO:0045570 26 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
gtp metabolic process GO:0046039 72 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
epithelium migration GO:0090132 148 0.011
aromatic compound catabolic process GO:0019439 166 0.011
axis specification GO:0009798 167 0.011
positive regulation of rab gtpase activity GO:0032851 7 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
reproductive system development GO:0061458 74 0.011
regulation of rab protein signal transduction GO:0032483 7 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.010
female meiotic division GO:0007143 70 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
histolysis GO:0007559 102 0.010
synaptic vesicle transport GO:0048489 50 0.010
carboxylic acid biosynthetic process GO:0046394 15 0.010
negative regulation of growth GO:0045926 84 0.010
nucleoside phosphate biosynthetic process GO:1901293 34 0.010
germarium derived egg chamber formation GO:0007293 101 0.010

schlank disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
nervous system disease DOID:863 0 0.039
disease of cellular proliferation DOID:14566 0 0.017
sensory system disease DOID:0050155 0 0.015
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.012