Drosophila melanogaster

54 known processes

blw (Dmel_CG3612)

bellwether

(Aliases: ATPsyn-alpha,CG3612,A2(2nd)27,l(2)01410,ms(2)01504,l(2)03972,l(2)59ABa,l(2)k00212,Dmel\CG3612,Blw,ms(2)Pry58F)

blw biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
atp metabolic process GO:0046034 49 0.938
Human Yeast Rat
nucleoside monophosphate metabolic process GO:0009123 52 0.908
Human Yeast Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.854
Human Yeast Rat
nad metabolic process GO:0019674 1 0.841
ribose phosphate biosynthetic process GO:0046390 28 0.836
Yeast Rat
thioester metabolic process GO:0035383 3 0.768
purine nucleoside monophosphate metabolic process GO:0009126 50 0.699
Human Yeast Rat
ribonucleoside monophosphate metabolic process GO:0009161 51 0.680
Human Yeast Rat
spermatogenesis GO:0007283 200 0.653
cellular respiration GO:0045333 26 0.624
ribonucleoside monophosphate catabolic process GO:0009158 39 0.613
Human Yeast Rat
organelle fission GO:0048285 340 0.567
small molecule metabolic process GO:0044281 305 0.532
Human Yeast Rat
ribonucleoside metabolic process GO:0009119 127 0.491
Human Yeast Rat
transmembrane transport GO:0055085 139 0.458
Yeast
organic acid metabolic process GO:0006082 103 0.430
ribonucleoside biosynthetic process GO:0042455 3 0.430
Yeast Rat
organonitrogen compound metabolic process GO:1901564 318 0.427
Human Yeast Rat
oxoacid metabolic process GO:0043436 103 0.421
organophosphate metabolic process GO:0019637 195 0.373
Human Yeast Rat
embryo development ending in birth or egg hatching GO:0009792 152 0.367
Worm
glycosyl compound metabolic process GO:1901657 127 0.349
Human Yeast Rat
maintenance of location GO:0051235 73 0.334
purine containing compound metabolic process GO:0072521 155 0.315
Human Yeast Rat
generation of precursor metabolites and energy GO:0006091 42 0.315
purine ribonucleotide metabolic process GO:0009150 145 0.314
Human Yeast Rat
purine ribonucleoside metabolic process GO:0046128 127 0.303
Human Yeast Rat
purine nucleoside metabolic process GO:0042278 127 0.291
Human Yeast Rat
nucleotide metabolic process GO:0009117 161 0.289
Human Yeast Rat
purine nucleoside triphosphate metabolic process GO:0009144 119 0.274
Human Yeast Rat
ribonucleotide biosynthetic process GO:0009260 28 0.270
Yeast Rat
carboxylic acid metabolic process GO:0019752 92 0.262
ribose phosphate metabolic process GO:0019693 145 0.238
Human Yeast Rat
microtubule organizing center organization GO:0031023 168 0.231
inorganic cation transmembrane transport GO:0098662 61 0.229
Yeast
acyl coa biosynthetic process GO:0071616 2 0.224
vesicle mediated transport GO:0016192 381 0.222
cation transport GO:0006812 110 0.219
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.219
Human Yeast Rat
nucleoside monophosphate biosynthetic process GO:0009124 4 0.217
Yeast Rat
determination of adult lifespan GO:0008340 137 0.207
Worm
cation transmembrane transport GO:0098655 88 0.199
Yeast
organelle assembly GO:0070925 198 0.197
purine nucleoside biosynthetic process GO:0042451 3 0.196
Yeast Rat
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.194
Yeast
cell death GO:0008219 279 0.192
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.187
Human Yeast Rat
spermatid differentiation GO:0048515 114 0.180
nucleoside phosphate metabolic process GO:0006753 162 0.174
Human Yeast Rat
centrosome organization GO:0051297 163 0.167
nucleoside triphosphate metabolic process GO:0009141 120 0.167
Human Yeast Rat
endocytosis GO:0006897 310 0.167
lipid storage GO:0019915 38 0.163
lipid localization GO:0010876 54 0.163
larval development GO:0002164 104 0.161
Worm
single organism catabolic process GO:0044712 228 0.160
Human Yeast Rat
nuclear division GO:0000280 332 0.159
acyl coa metabolic process GO:0006637 3 0.157
nicotinamide nucleotide metabolic process GO:0046496 2 0.144
tricarboxylic acid metabolic process GO:0072350 1 0.137
thioester biosynthetic process GO:0035384 2 0.136
atp biosynthetic process GO:0006754 2 0.130
Yeast
cellular response to chemical stimulus GO:0070887 199 0.125
aging GO:0007568 143 0.122
Worm
energy derivation by oxidation of organic compounds GO:0015980 32 0.117
striated muscle myosin thick filament assembly GO:0071688 3 0.116
atp catabolic process GO:0006200 38 0.116
Human Yeast Rat
male gamete generation GO:0048232 201 0.115
purine containing compound biosynthetic process GO:0072522 30 0.110
Yeast Rat
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.109
Human Yeast Rat
purine nucleotide metabolic process GO:0006163 146 0.105
Human Yeast Rat
carbohydrate derivative biosynthetic process GO:1901137 85 0.105
Yeast Rat
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.102
Yeast
growth GO:0040007 359 0.097
spindle organization GO:0007051 253 0.096
metal ion homeostasis GO:0055065 44 0.095
nucleotide biosynthetic process GO:0009165 34 0.094
Yeast Rat
translation GO:0006412 69 0.085
catabolic process GO:0009056 409 0.085
Human Yeast Rat
muscle structure development GO:0061061 224 0.084
ribonucleotide metabolic process GO:0009259 145 0.081
Human Yeast Rat
ion transport GO:0006811 145 0.081
Yeast
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.081
Yeast Rat
response to insulin GO:0032868 29 0.079
organophosphate biosynthetic process GO:0090407 46 0.079
Yeast Rat
negative regulation of cell differentiation GO:0045596 143 0.076
sperm mitochondrion organization GO:0030382 7 0.076
glycosyl compound biosynthetic process GO:1901659 3 0.075
Yeast Rat
purine nucleotide biosynthetic process GO:0006164 29 0.074
Yeast Rat
phagocytosis GO:0006909 215 0.072
carboxylic acid catabolic process GO:0046395 16 0.072
centrosome cycle GO:0007098 137 0.070
citrate metabolic process GO:0006101 0 0.069
nucleoside metabolic process GO:0009116 127 0.068
Human Yeast Rat
aromatic compound catabolic process GO:0019439 166 0.067
Human Yeast Rat
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.064
Yeast Rat
response to wounding GO:0009611 94 0.063
purine ribonucleotide biosynthetic process GO:0009152 28 0.060
Yeast Rat
imaginal disc derived wing morphogenesis GO:0007476 337 0.059
nadh metabolic process GO:0006734 1 0.059
carbohydrate derivative metabolic process GO:1901135 217 0.059
Human Yeast Rat
mitotic nuclear division GO:0007067 213 0.058
mitotic spindle organization GO:0007052 220 0.058
body morphogenesis GO:0010171 2 0.057
oxidation reduction process GO:0055114 123 0.056
organic cyclic compound catabolic process GO:1901361 168 0.052
Human Yeast Rat
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.050
Yeast
wound healing GO:0042060 75 0.049
organic acid catabolic process GO:0016054 16 0.049
ribonucleoside triphosphate metabolic process GO:0009199 119 0.048
Human Yeast Rat
purine nucleoside monophosphate catabolic process GO:0009128 38 0.048
Human Yeast Rat
multicellular organismal aging GO:0010259 140 0.047
Worm
programmed cell death GO:0012501 257 0.047
Worm
myofibril assembly GO:0030239 36 0.046
response to organic substance GO:0010033 284 0.046
small molecule catabolic process GO:0044282 21 0.044
immune response GO:0006955 246 0.043
nucleoside monophosphate catabolic process GO:0009125 39 0.043
Human Yeast Rat
meiotic nuclear division GO:0007126 151 0.043
nucleoside biosynthetic process GO:0009163 3 0.042
Yeast Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.042
monocarboxylic acid metabolic process GO:0032787 29 0.041
biological adhesion GO:0022610 138 0.041
purine ribonucleoside biosynthetic process GO:0046129 3 0.040
Yeast Rat
organic substance catabolic process GO:1901575 308 0.040
Human Yeast Rat
pyridine containing compound metabolic process GO:0072524 3 0.040
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.039
Yeast Rat
muscle cell differentiation GO:0042692 103 0.039
regulation of organelle organization GO:0033043 196 0.039
oxidative phosphorylation GO:0006119 9 0.038
neurological system process GO:0050877 358 0.038
regulation of growth GO:0040008 233 0.038
single organism carbohydrate catabolic process GO:0044724 7 0.037
cellular carbohydrate catabolic process GO:0044275 2 0.037
meiotic cell cycle GO:0051321 171 0.037
response to decreased oxygen levels GO:0036293 58 0.037
positive regulation of developmental process GO:0051094 143 0.036
organic substance transport GO:0071702 257 0.036
nucleobase containing compound catabolic process GO:0034655 165 0.035
Human Yeast Rat
cellular protein complex assembly GO:0043623 71 0.035
ion transmembrane transport GO:0034220 122 0.034
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 108 0.034
Human Yeast Rat
cellular nitrogen compound catabolic process GO:0044270 165 0.033
Human Yeast Rat
response to metal ion GO:0010038 23 0.033
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.032
Human Yeast Rat
cell motility GO:0048870 251 0.032
organonitrogen compound biosynthetic process GO:1901566 117 0.032
Yeast Rat
cytoplasmic microtubule organization GO:0031122 22 0.032
lateral inhibition GO:0046331 206 0.031
regulation of cell death GO:0010941 173 0.031
death GO:0016265 284 0.031
Worm
inorganic ion transmembrane transport GO:0098660 73 0.031
Yeast
fatty acid metabolic process GO:0006631 20 0.031
response to oxygen containing compound GO:1901700 200 0.030
negative regulation of signal transduction GO:0009968 206 0.030
striated muscle cell development GO:0055002 50 0.029
nucleoside phosphate biosynthetic process GO:1901293 34 0.029
Yeast Rat
cellular component assembly involved in morphogenesis GO:0010927 151 0.028
mitochondrion organization GO:0007005 65 0.027
monovalent inorganic cation transport GO:0015672 40 0.027
Yeast
negative regulation of growth GO:0045926 84 0.027
gland development GO:0048732 191 0.026
actomyosin structure organization GO:0031032 56 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
protein complex assembly GO:0006461 200 0.026
chromosome segregation GO:0007059 157 0.026
gene silencing GO:0016458 138 0.026
cellular response to insulin stimulus GO:0032869 28 0.025
response to abiotic stimulus GO:0009628 341 0.025
nucleoside triphosphate catabolic process GO:0009143 108 0.024
Human Yeast Rat
developmental growth GO:0048589 280 0.024
regulation of necrotic cell death GO:0010939 1 0.024
developmental programmed cell death GO:0010623 138 0.023
proteolysis GO:0006508 192 0.023
digestive tract development GO:0048565 149 0.023
regulation of cellular response to insulin stimulus GO:1900076 17 0.022
monocarboxylic acid catabolic process GO:0072329 10 0.022
striated muscle tissue development GO:0014706 27 0.022
cellular macromolecule localization GO:0070727 220 0.022
negative regulation of gene expression GO:0010629 387 0.021
positive regulation of programmed cell death GO:0043068 62 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
Human Yeast Rat
aerobic respiration GO:0009060 11 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
Human Yeast Rat
regulation of localization GO:0032879 275 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
Human Yeast Rat
chromosome organization GO:0051276 360 0.020
nucleoside triphosphate biosynthetic process GO:0009142 2 0.019
Yeast
nucleotide catabolic process GO:0009166 109 0.019
Human Yeast Rat
negative regulation of developmental process GO:0051093 201 0.019
tube morphogenesis GO:0035239 191 0.019
reproductive structure development GO:0048608 74 0.019
lipid metabolic process GO:0006629 121 0.019
response to oxygen levels GO:0070482 59 0.018
regulation of programmed cell death GO:0043067 152 0.018
tube development GO:0035295 244 0.018
heart development GO:0007507 82 0.018
regionalization GO:0003002 416 0.017
regulation of molecular function GO:0065009 217 0.017
defense response GO:0006952 300 0.016
muscle tissue development GO:0060537 30 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
Human Yeast Rat
cellular catabolic process GO:0044248 372 0.016
Human Yeast Rat
cellular macromolecular complex assembly GO:0034622 153 0.016
regulation of lipid catabolic process GO:0050994 3 0.016
taxis GO:0042330 304 0.016
pyruvate metabolic process GO:0006090 7 0.015
protein complex biogenesis GO:0070271 201 0.015
regeneration GO:0031099 16 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
Human Yeast Rat
chromatin organization GO:0006325 207 0.015
cell proliferation GO:0008283 299 0.015
Human
single organism biosynthetic process GO:0044711 206 0.015
Yeast Rat
purine nucleotide catabolic process GO:0006195 109 0.015
Human Yeast Rat
negative regulation of multicellular organismal process GO:0051241 142 0.015
chemotaxis GO:0006935 249 0.015
cellular response to organic substance GO:0071310 132 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
Human Yeast Rat
larval midgut cell programmed cell death GO:0035096 19 0.014
salivary gland morphogenesis GO:0007435 145 0.014
protein transport GO:0015031 155 0.014
cellularization GO:0007349 90 0.014
mitochondrial fusion GO:0008053 7 0.014
response to hypoxia GO:0001666 53 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
Human Yeast Rat
actin cytoskeleton organization GO:0030036 206 0.014
response to oxidative stress GO:0006979 86 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.013
heterocycle catabolic process GO:0046700 166 0.013
Human Yeast Rat
electron transport chain GO:0022900 14 0.013
oxidoreduction coenzyme metabolic process GO:0006733 2 0.013
regulation of mitosis GO:0007088 56 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of membrane potential GO:0042391 35 0.012
negative regulation of stem cell proliferation GO:2000647 30 0.012
cell division GO:0051301 248 0.012
regulation of transport GO:0051049 181 0.012
myosin filament assembly GO:0031034 5 0.012
positive regulation of growth GO:0045927 75 0.012
regulation of response to oxidative stress GO:1902882 4 0.012
spermatid development GO:0007286 98 0.012
head development GO:0060322 135 0.012
macromolecular complex assembly GO:0065003 256 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
regulation of cellular component biogenesis GO:0044087 201 0.011
actin filament based process GO:0030029 220 0.011
single organism intracellular transport GO:1902582 207 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of transmembrane transport GO:0034762 27 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
Human Yeast Rat
regulation of cell proliferation GO:0042127 163 0.011
Human
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
negative regulation of neuroblast proliferation GO:0007406 27 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
Human Yeast Rat
cellular protein modification process GO:0006464 438 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
nuclear transport GO:0051169 72 0.010
mitotic cytokinesis GO:0000281 50 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
brain development GO:0007420 120 0.010
tissue death GO:0016271 102 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
anion transport GO:0006820 41 0.010
sister chromatid segregation GO:0000819 92 0.010

blw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.028
sensory system disease DOID:0050155 0 0.019
nervous system disease DOID:863 0 0.019
disease of cellular proliferation DOID:14566 0 0.013
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
cancer DOID:162 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010