Drosophila melanogaster

164 known processes

Dl (Dmel_CG3619)

Delta

(Aliases: DL,1423/11,anon-WO0118547.269,1053/14,0926/11,CT12133,1119/09,l(3)92Ab,dmDelta,CG3619,C1,1304/03,1485/04,D,Dmel\CG3619,0495/20,delta,l(3)05151,1440/11,l(3)j8C3,delta D1,E(ls)2)

Dl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 135 0.999
Zebrafish
regionalization GO:0003002 416 0.999
stem cell maintenance GO:0019827 67 0.995
cell cell signaling involved in cell fate commitment GO:0045168 210 0.986
negative regulation of cell differentiation GO:0045596 143 0.985
formation of anatomical boundary GO:0048859 37 0.984
cell fate determination GO:0001709 91 0.984
compound eye morphogenesis GO:0001745 249 0.981
negative regulation of developmental process GO:0051093 201 0.977
pericardium development GO:0060039 2 0.964
Mouse
skin development GO:0043588 65 0.964
Mouse
lateral inhibition GO:0046331 206 0.952
formation of organ boundary GO:0010160 30 0.929
border follicle cell migration GO:0007298 113 0.928
regulation of cell differentiation GO:0045595 302 0.918
compound eye development GO:0048749 307 0.895
gliogenesis GO:0042063 80 0.878
stem cell development GO:0048864 79 0.870
urogenital system development GO:0001655 72 0.870
Mouse
eye antennal disc development GO:0035214 60 0.867
germarium derived egg chamber formation GO:0007293 101 0.865
regulation of cell development GO:0060284 215 0.864
photoreceptor cell fate commitment GO:0046552 41 0.842
compound eye photoreceptor cell differentiation GO:0001751 140 0.824
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.812
Mouse
neuron fate commitment GO:0048663 50 0.807
Human
dorsal ventral pattern formation GO:0009953 133 0.798
oocyte construction GO:0007308 112 0.763
positive regulation of cellular biosynthetic process GO:0031328 316 0.754
Mouse
axis specification GO:0009798 167 0.732
Mouse
dendrite regeneration GO:0031104 2 0.729
photoreceptor cell differentiation GO:0046530 170 0.703
eye photoreceptor cell differentiation GO:0001754 145 0.701
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.689
regulation of neurogenesis GO:0050767 158 0.679
heart development GO:0007507 82 0.672
Mouse
regulation of epidermal cell differentiation GO:0045604 3 0.657
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 8 0.654
Mouse
organ formation GO:0048645 39 0.653
eye photoreceptor cell fate commitment GO:0042706 37 0.632
left right axis specification GO:0070986 1 0.630
Mouse
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.626
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.608
forebrain development GO:0030900 2 0.608
Zebrafish
oocyte morphogenesis GO:0048601 3 0.588
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.587
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316 1 0.584
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.576
meiotic nuclear envelope disassembly GO:0051078 2 0.571
negative regulation of neurogenesis GO:0050768 53 0.567
response to radiation GO:0009314 155 0.564
germ line stem cell division GO:0042078 25 0.556
hindgut morphogenesis GO:0007442 58 0.547
cardioblast cell fate specification GO:0042685 9 0.539
mushroom body development GO:0016319 70 0.538
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.536
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.507
sensory organ boundary specification GO:0008052 22 0.486
sensory organ morphogenesis GO:0090596 260 0.478
positive regulation of protein import into nucleus translocation GO:0033160 2 0.475
embryonic heart tube development GO:0035050 22 0.466
Mouse
negative regulation of response to stimulus GO:0048585 258 0.448
Rat Fly
positive regulation of nervous system development GO:0051962 69 0.444
Rat
imaginal disc pattern formation GO:0007447 91 0.444
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.441
Mouse
oocyte differentiation GO:0009994 145 0.433
dorsal closure leading edge cell differentiation GO:0046663 2 0.430
epithelial cell proliferation GO:0050673 15 0.418
Zebrafish
oocyte fate commitment GO:0048600 2 0.410
cell fate commitment involved in pattern specification GO:0060581 31 0.400
Human
dorsal ventral axis specification GO:0009950 66 0.400
asymmetric cell division GO:0008356 37 0.399
establishment of ommatidial planar polarity GO:0042067 49 0.397
meiotic chromosome movement towards spindle pole GO:0016344 1 0.381
regulation of centriole replication GO:0046599 2 0.375
determination of left right symmetry GO:0007368 9 0.360
Zebrafish Mouse
oocyte axis specification GO:0007309 108 0.357
positive regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0090282 1 0.350
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.339
juvenile hormone mediated signaling pathway GO:0035626 3 0.321
dna templated transcriptional start site selection GO:0001173 1 0.321
regulation of cell fate specification GO:0042659 27 0.316
meiotic spindle checkpoint GO:0044779 1 0.313
negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902166 1 0.306
pericardium morphogenesis GO:0003344 2 0.299
Mouse
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 1 0.296
regulation of nervous system development GO:0051960 248 0.294
regulation of ran gtpase activity GO:0032316 1 0.292
eye photoreceptor cell development GO:0042462 81 0.286
positive regulation of ribosome biogenesis GO:0090070 3 0.285
negative regulation of dna templated transcription initiation GO:2000143 1 0.281
segmentation GO:0035282 207 0.280
oocyte development GO:0048599 124 0.275
specification of segmental identity antennal segment GO:0007383 2 0.271
germ line stem cell maintenance GO:0030718 50 0.265
negative regulation of mrna 3 end processing GO:0031441 3 0.263
regulation of heart morphogenesis GO:2000826 3 0.259
regulation of epithelial cell differentiation GO:0030856 4 0.254
Mouse
eye morphogenesis GO:0048592 260 0.254
maintenance of chromatin silencing GO:0006344 0 0.250
ovulation cycle GO:0042698 1 0.247
negative regulation of transcription from rna polymerase iii promoter GO:0016480 2 0.241
r3 r4 cell fate commitment GO:0007464 10 0.240
nurse cell nucleus anchoring GO:0007302 1 0.235
cell fate specification GO:0001708 71 0.233
negative regulation of epithelial cell migration GO:0010633 1 0.233
Human Zebrafish Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.233
embryonic hindgut morphogenesis GO:0048619 48 0.229
heart induction GO:0003129 3 0.225
p granule organization GO:0030719 4 0.221
negative regulation of signaling GO:0023057 219 0.217
Rat Fly
regulation of neuron differentiation GO:0045664 103 0.216
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.214
regulation of meiotic cell cycle phase transition GO:1901993 1 0.214
male germline ring canal formation GO:0030726 3 0.211
meiotic dna repair synthesis GO:0000711 3 0.211
positive regulation of epithelial cell differentiation GO:0030858 1 0.208
peptidyl tyrosine modification GO:0018212 24 0.205
regulation of cardioblast cell fate specification GO:0042686 8 0.204
negative regulation of nurse cell apoptotic process GO:0045849 2 0.199
dna integration GO:0015074 1 0.194
negative regulation of ras gtpase activity GO:0034261 1 0.191
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 1 0.190
glycosyl compound catabolic process GO:1901658 112 0.189
release of cytoplasmic sequestered nf kappab GO:0008588 1 0.189
positive regulation of cell maturation GO:1903431 2 0.189
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.189
female sex determination GO:0030237 3 0.187
developmental growth involved in morphogenesis GO:0060560 65 0.186
negative regulation of mrna polyadenylation GO:1900364 2 0.184
cell morphogenesis involved in malpighian tubule morphogenesis GO:0061336 1 0.180
positive regulation of chromatin silencing at telomere GO:0031940 2 0.179
stress granule disassembly GO:0035617 1 0.179
regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0000117 1 0.177
protein localization to nucleus GO:0034504 55 0.176
negative regulation of apoptotic process GO:0043066 63 0.176
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.175
Mouse
regulation of hematopoietic stem cell differentiation GO:1902036 1 0.175
maintenance of sister chromatid cohesion GO:0034086 1 0.168
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 2 0.166
negative regulation of cellular metabolic process GO:0031324 382 0.165
Mouse
germarium derived cystoblast division GO:0048142 3 0.164
microtubule sliding GO:0051012 3 0.164
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.163
stem cell differentiation GO:0048863 117 0.159
gastrulation GO:0007369 70 0.157
regulation of epithelial cell proliferation GO:0050678 4 0.153
establishment or maintenance of cell polarity GO:0007163 167 0.153
regulation of trichome morphogenesis GO:2000039 3 0.152
regulation of programmed cell death GO:0043067 152 0.152
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 2 0.152
regulation of spindle checkpoint GO:0090231 2 0.148
positive regulation of pole plasm oskar mrna localization GO:0045856 2 0.148
nucleotide catabolic process GO:0009166 109 0.145
negative regulation of multicellular organismal process GO:0051241 142 0.142
negative regulation of cellular catabolic process GO:0031330 34 0.141
regulation of preblastoderm mitotic cell cycle GO:0007347 1 0.141
centripetally migrating follicle cell migration GO:0060269 1 0.141
crystal cell differentiation GO:0042688 7 0.139
Fly
ganglion mother cell fate determination GO:0007402 2 0.139
regulation of chromosome condensation GO:0060623 1 0.133
response to uv b GO:0010224 1 0.132
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.132
actin filament based process GO:0030029 220 0.131
magnesium ion homeostasis GO:0010960 1 0.131
trichome morphogenesis GO:0010090 3 0.130
metaphase anaphase transition of meiotic cell cycle GO:0044785 1 0.127
regulation of apoptotic process GO:0042981 130 0.127
cytoplasmic sequestering of nf kappab GO:0007253 1 0.127
positive regulation of rna metabolic process GO:0051254 271 0.126
Mouse
regulation of compound eye photoreceptor development GO:0045314 12 0.126
regulation of mitotic centrosome separation GO:0046602 3 0.125
cell division GO:0051301 248 0.124
establishment of localization in cell GO:0051649 402 0.124
oocyte nucleus migration involved in oocyte dorsal ventral axis specification GO:0007312 4 0.121
cell proliferation GO:0008283 299 0.120
regulation of metaphase anaphase transition of meiotic cell cycle GO:1902102 1 0.120
cell motility GO:0048870 251 0.119
regulation of cell proliferation GO:0042127 163 0.118
male germ cell proliferation GO:0002176 1 0.118
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.117
trichome differentiation GO:0010026 3 0.116
organ induction GO:0001759 3 0.116
appendage development GO:0048736 401 0.115
promoter clearance from rna polymerase ii promoter GO:0001111 1 0.115
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.114
prostaglandin biosynthetic process GO:0001516 1 0.109
r7 cell differentiation GO:0045466 43 0.109
synaptic vesicle budding from presynaptic membrane GO:0016185 1 0.108
sensory organ precursor cell fate determination GO:0016360 19 0.106
cell cell junction maintenance GO:0045217 1 0.106
positive regulation of neurogenesis GO:0050769 41 0.104
Rat
cytokinesis completion of separation GO:0007109 1 0.103
response to red light GO:0010114 2 0.103
response to light stimulus GO:0009416 124 0.102
cell maturation GO:0048469 144 0.101
anterior posterior axis specification follicular epithelium GO:0030714 2 0.101
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 1 0.100
meiotic sister chromatid cohesion centromeric GO:0051754 2 0.099
anterior region determination GO:0007355 1 0.099
ribonucleoside metabolic process GO:0009119 127 0.099
histone mrna catabolic process GO:0071044 0 0.098
enzyme linked receptor protein signaling pathway GO:0007167 179 0.098
Zebrafish
leg disc development GO:0035218 92 0.098
nuclear axial expansion GO:0035191 3 0.096
brain development GO:0007420 120 0.095
Zebrafish
post embryonic appendage morphogenesis GO:0035120 385 0.095
response to growth factor GO:0070848 31 0.094
Human Zebrafish
negative regulation of pigment cell differentiation GO:0050941 1 0.094
peptidyl arginine omega n methylation GO:0035247 4 0.094
regulation of presynaptic membrane organization GO:1901629 1 0.094
digestive tract morphogenesis GO:0048546 127 0.093
Zebrafish
epithelial cell differentiation GO:0030855 322 0.093
positive regulation of protein modification process GO:0031401 58 0.092
small gtpase mediated signal transduction GO:0007264 88 0.092
negative regulation of phosphatase activity GO:0010923 3 0.092
apoptotic process GO:0006915 159 0.091
positive regulation of cyclin catabolic process GO:2000600 2 0.091
negative regulation of cell development GO:0010721 62 0.091
genital disc sexually dimorphic development GO:0035263 4 0.091
establishment of epithelial cell polarity GO:0090162 13 0.090
negative regulation of metaphase anaphase transition of meiotic cell cycle GO:1902103 1 0.090
transposon integration GO:0070893 1 0.090
purine nucleoside triphosphate metabolic process GO:0009144 119 0.089
regulation of cyclin catabolic process GO:2000598 2 0.089
hematopoietic stem cell differentiation GO:0060218 1 0.088
Zebrafish
histone h3 k4 demethylation GO:0034720 3 0.088
regulation of cohesin localization to chromatin GO:0071922 2 0.087
notch signaling pathway GO:0007219 120 0.087
r3 r4 cell differentiation GO:0048056 12 0.087
morphogenesis of an epithelium GO:0002009 276 0.086
Zebrafish Mouse
negative regulation of sister chromatid cohesion GO:0045875 1 0.085
positive regulation of stem cell proliferation GO:2000648 8 0.085
regulation of organ formation GO:0003156 3 0.085
negative regulation of gene silencing by mirna GO:0060965 2 0.085
negative regulation of activin receptor signaling pathway GO:0032926 1 0.085
positive regulation of ran gtpase activity GO:0032853 1 0.084
stem cell proliferation GO:0072089 88 0.081
hindgut development GO:0061525 58 0.081
purine ribonucleoside catabolic process GO:0046130 112 0.080
regulation of mrna polyadenylation GO:1900363 2 0.080
detection of mechanical stimulus involved in sensory perception of touch GO:0050976 2 0.079
histone h4 acetylation involved in response to dna damage stimulus GO:2000776 1 0.078
cell migration GO:0016477 238 0.078
mrna cleavage GO:0006379 2 0.077
conversion of ds sirna to ss sirna involved in rna interference GO:0033168 1 0.077
cuticle hydrocarbon biosynthetic process GO:0006723 2 0.076
ribonucleoprotein complex disassembly GO:0032988 1 0.076
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 1 0.076
peptidyl serine modification GO:0018209 7 0.076
transcriptional start site selection at rna polymerase ii promoter GO:0001174 1 0.075
sex specific pigmentation GO:0048071 1 0.075
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.075
regulation of cell cell adhesion mediated by cadherin GO:2000047 1 0.074
negative regulation of programmed cell death GO:0043069 72 0.074
anterior head segmentation GO:0035288 3 0.073
regulation of eye photoreceptor cell development GO:0042478 13 0.073
cenp a containing chromatin organization GO:0061641 3 0.072
negative regulation of meiotic cell cycle phase transition GO:1901994 1 0.071
positive regulation of stem cell maintenance GO:1902459 1 0.071
regulation of wnt signaling pathway GO:0030111 68 0.071
activation of ral gtpase activity GO:0032859 1 0.071
myosin ii filament assembly GO:0031036 1 0.069
eye antennal disc morphogenesis GO:0007455 34 0.069
icosanoid biosynthetic process GO:0046456 1 0.068
regulation of histone h4 acetylation involved in response to dna damage stimulus GO:2000873 1 0.068
compound eye photoreceptor fate commitment GO:0001752 36 0.068
regulation of heterotypic cell cell adhesion GO:0034114 1 0.068
postsynaptic density organization GO:0097106 1 0.068
meiotic spindle assembly checkpoint GO:0033316 1 0.067
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 1 0.067
organic substance transport GO:0071702 257 0.067
renal tubule development GO:0061326 64 0.067
Mouse
positive regulation of store operated calcium channel activity GO:1901341 1 0.066
regulation of cell cycle checkpoint GO:1901976 2 0.065
regulation of cell death GO:0010941 173 0.065
peripheral nervous system development GO:0007422 52 0.065
regulation of notch signaling pathway GO:0008593 100 0.065
Zebrafish Mouse Rat Fly
respiratory system development GO:0060541 213 0.064
microtubule cytoskeleton organization involved in establishment of planar polarity GO:0090176 3 0.064
cenp a containing nucleosome assembly GO:0034080 3 0.064
synapse assembly involved in innervation GO:0060386 1 0.064
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.063
external genitalia morphogenesis GO:0035261 1 0.063
positive regulation of transposition GO:0010530 1 0.063
border follicle cell delamination GO:0030709 3 0.062
neural precursor cell proliferation GO:0061351 75 0.062
Mouse
regulation of spindle assembly involved in mitosis GO:1901673 3 0.061
suture of dorsal opening GO:0007396 1 0.061
regulation of compound eye retinal cell apoptotic process GO:1901692 2 0.060
astral microtubule nucleation GO:0030954 2 0.060
regulation of molecular function GO:0065009 217 0.059
regulation of protein modification process GO:0031399 112 0.059
compound eye retinal cell apoptotic process GO:1990010 2 0.058
regulation of production of small rna involved in gene silencing by rna GO:0070920 3 0.058
subsynaptic reticulum organization GO:1990255 2 0.058
imaginal disc derived appendage development GO:0048737 399 0.058
cytoskeleton dependent cytoplasmic transport nurse cell to oocyte GO:0019749 2 0.058
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.058
positive regulation of ral gtpase activity GO:0032852 1 0.057
positive regulation of muscle organ development GO:0048636 6 0.057
protein localization to nuclear envelope GO:0090435 2 0.057
central nervous system development GO:0007417 201 0.057
Human Zebrafish Rat
regulation of transport GO:0051049 181 0.057
stem cell division GO:0017145 69 0.057
regulation of centriole centriole cohesion GO:0030997 1 0.057
meiotic recombination checkpoint GO:0051598 1 0.056
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.056
Mouse
negative regulation of cardioblast differentiation GO:0051892 7 0.056
dsdna loop formation GO:0090579 2 0.055
cardiac cell fate specification GO:0060912 10 0.055
actin filament organization GO:0007015 126 0.055
positive regulation of golgi to plasma membrane protein transport GO:0042998 2 0.055
positive regulation of microtubule nucleation GO:0090063 1 0.054
positive regulation of apoptotic process involved in morphogenesis GO:1902339 2 0.053
positive regulation of microtubule depolymerization GO:0031117 2 0.053
wnt signaling pathway involved in heart development GO:0003306 3 0.052
positive regulation of eye pigmentation GO:0048075 2 0.052
histone h3 k36 methylation GO:0010452 1 0.051
sister chromatid biorientation GO:0031134 1 0.051
positive regulation of eye photoreceptor cell development GO:0042479 2 0.051
positive regulation of cytoplasmic mrna processing body assembly GO:0010606 1 0.051
mitotic nuclear envelope reassembly GO:0007084 1 0.051
dna methylation on cytosine GO:0032776 1 0.051
autophagic vacuole maturation GO:0097352 2 0.051
haltere disc morphogenesis GO:0007481 1 0.051
positive regulation of stem cell differentiation GO:2000738 3 0.051
hair cell differentiation GO:0035315 47 0.051
Mouse
fatty acid derivative biosynthetic process GO:1901570 1 0.051
retinal cell apoptotic process GO:1990009 2 0.050
eye development GO:0001654 323 0.050
regulation of small gtpase mediated signal transduction GO:0051056 93 0.049
maintenance of neuroblast polarity GO:0045201 3 0.049
septin cytoskeleton organization GO:0032185 1 0.049
spindle assembly involved in female meiosis ii GO:0007058 4 0.049
microvillar actin bundle assembly GO:0030034 1 0.048
imaginal disc derived wing morphogenesis GO:0007476 337 0.047
regulation of cytokinesis actomyosin contractile ring assembly GO:2000431 2 0.047
mesodermal cell fate specification GO:0007501 2 0.047
positive regulation of developmental process GO:0051094 143 0.047
Rat
regulation of cytoplasmic mrna processing body assembly GO:0010603 4 0.047
positive regulation of compound eye retinal cell apoptotic process GO:1901694 1 0.047
nucleotide excision repair dna damage recognition GO:0000715 0 0.046
female pronucleus assembly GO:0035038 2 0.046
regulation of shoot system development GO:0048831 3 0.046
regulation of glial cell differentiation GO:0045685 1 0.046
Rat
sirna loading onto risc involved in rna interference GO:0035087 4 0.046
axon development GO:0061564 297 0.045
membrane addition at site of cytokinesis GO:0007107 1 0.045
myosin ii filament organization GO:0031038 1 0.045
regulation of synaptic vesicle clustering GO:2000807 1 0.045
imaginal disc lineage restriction GO:0035161 2 0.045
embryonic organ development GO:0048568 50 0.045
Zebrafish Mouse
histone h4 r3 methylation GO:0043985 1 0.044
maintenance of polarity of follicular epithelium GO:0042248 2 0.044
low density lipoprotein receptor particle metabolic process GO:0032799 1 0.044
positive regulation of cellular response to x ray GO:2000685 2 0.044
promoter clearance during dna templated transcription GO:0001109 1 0.044
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.043
lipoprotein catabolic process GO:0042159 2 0.043
glial cell development GO:0021782 27 0.043
positive regulation of posttranscriptional gene silencing GO:0060148 5 0.043
larval wandering behavior GO:0035180 2 0.043
peptide cross linking GO:0018149 2 0.042
telencephalon development GO:0021537 2 0.042
leaf development GO:0048366 3 0.042
epithelial tube morphogenesis GO:0060562 88 0.042
Zebrafish Mouse
muscle cell development GO:0055001 50 0.042
maintenance of mitotic sister chromatid cohesion GO:0034088 1 0.042
cytoskeletal anchoring at plasma membrane GO:0007016 1 0.042
cell fate determination involved in pattern specification GO:0060582 19 0.041
negative regulation of mrna metabolic process GO:1903312 5 0.041
compound eye photoreceptor development GO:0042051 78 0.041
regulation of ran protein signal transduction GO:0032015 1 0.041
organelle inheritance GO:0048308 2 0.040
regulation of protein catabolic process GO:0042176 55 0.039
regulation of ral protein signal transduction GO:0032485 1 0.039
chromatin remodeling at centromere GO:0031055 3 0.039
negative regulation of rho gtpase activity GO:0034259 1 0.039

Dl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
organ system benign neoplasm DOID:0060085 0 0.279
pilomatrixoma DOID:5374 0 0.279
hair follicle neoplasm DOID:5375 0 0.279
benign neoplasm DOID:0060072 0 0.279
disease of cellular proliferation DOID:14566 0 0.279
skin benign neoplasm DOID:3165 0 0.279
integumentary system benign neoplasm DOID:0060121 0 0.279
familial meningioma DOID:4586 0 0.266
nervous system cancer DOID:3093 0 0.266
central nervous system cancer DOID:3620 0 0.266
cancer DOID:162 0 0.266
organ system cancer DOID:0050686 0 0.266
meningioma DOID:3565 0 0.266
artery disease DOID:0050828 0 0.231
disease of anatomical entity DOID:7 0 0.231
Human
vascular disease DOID:178 0 0.231
cardiovascular system disease DOID:1287 0 0.231
aortic disease DOID:520 0 0.231
hajdu cheney syndrome DOID:2736 0 0.211
urinary bladder cancer DOID:11054 0 0.191
urinary system cancer DOID:3996 0 0.191
costello syndrome DOID:0050469 0 0.189
leopard syndrome DOID:14291 0 0.189
gastrointestinal system cancer DOID:3119 0 0.186
liver cancer DOID:3571 0 0.186
pancreatic carcinoma DOID:4905 0 0.182
endocrine gland cancer DOID:170 0 0.182
pancreatic cancer DOID:1793 0 0.182
disease of metabolism DOID:0014667 0 0.181
hemochromatosis DOID:2352 0 0.181
inherited metabolic disorder DOID:655 0 0.181
metal metabolism disorder DOID:896 0 0.181
nervous system benign neoplasm DOID:0060115 0 0.157
aortic valve stenosis DOID:1712 0 0.154
heart disease DOID:114 0 0.154
heart valve disease DOID:4079 0 0.154
aortic valve disease DOID:62 0 0.154
myopathy DOID:423 0 0.140
muscular disease DOID:0080000 0 0.140
cardiomyopathy DOID:0050700 0 0.140
intrinsic cardiomyopathy DOID:0060036 0 0.140
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.140
musculoskeletal system disease DOID:17 0 0.140
Human
muscle tissue disease DOID:66 0 0.140
hepatobiliary disease DOID:3118 0 0.135
gastrointestinal system disease DOID:77 0 0.135
liver disease DOID:409 0 0.135
alagille syndrome DOID:9245 0 0.135
aortic aneurysm DOID:3627 0 0.114
neuroma DOID:2001 0 0.112
head and neck squamous cell carcinoma DOID:5520 0 0.110
head and neck carcinoma DOID:1542 0 0.110
head and neck cancer DOID:11934 0 0.110
thyroid cancer DOID:1781 0 0.108
myeloma DOID:0070004 0 0.100
hemorrhagic thrombocythemia DOID:2224 0 0.100
chronic myeloproliferative disease DOID:2226 0 0.100
immune system cancer DOID:0060083 0 0.100
hematologic cancer DOID:2531 0 0.100
bone marrow cancer DOID:4960 0 0.100
female reproductive system disease DOID:229 0 0.099
ovarian disease DOID:1100 0 0.099
reproductive system disease DOID:15 0 0.099
premature ovarian failure DOID:5426 0 0.099
muscular dystrophy DOID:9884 0 0.098
emery dreifuss muscular dystrophy DOID:11726 0 0.098
neurilemmoma DOID:3192 0 0.093
neurilemmomatosis DOID:3204 0 0.093
non syndromic intellectual disability DOID:0050889 0 0.088
disease of mental health DOID:150 0 0.088
developmental disorder of mental health DOID:0060037 0 0.088
specific developmental disorder DOID:0060038 0 0.088
non specific x linked mental retardation DOID:0050776 0 0.088
intellectual disability DOID:1059 0 0.088
proteus syndrome DOID:13482 0 0.084
physical disorder DOID:0080015 0 0.084
musculoskeletal system cancer DOID:0060100 0 0.078
connective tissue cancer DOID:201 0 0.078
bone cancer DOID:184 0 0.078
integumentary system cancer DOID:0060122 0 0.077
fibrodysplasia ossificans progressiva DOID:13374 0 0.075
connective tissue disease DOID:65 0 0.075
Human
brain cancer DOID:1319 0 0.070
leukocyte adhesion deficiency DOID:6612 0 0.070
bannayan riley ruvalcaba syndrome DOID:0050657 0 0.065
hereditary hemorrhagic telangiectasia DOID:1270 0 0.064
thoracic aortic aneurysm DOID:14004 0 0.060
sleep disorder DOID:535 0 0.056
advanced sleep phase syndrome DOID:0050628 0 0.056
reproductive organ cancer DOID:193 0 0.055
female reproductive organ cancer DOID:120 0 0.055
uterine cancer DOID:363 0 0.055
endometrial cancer DOID:1380 0 0.055
juvenile polyposis syndrome DOID:0050787 0 0.054
li fraumeni syndrome DOID:3012 0 0.053
weaver syndrome DOID:14731 0 0.048
skin melanoma DOID:8923 0 0.048
skin cancer DOID:4159 0 0.048
motor neuron disease DOID:231 0 0.047
amyotrophic lateral sclerosis type 19 DOID:0060210 0 0.047
central nervous system disease DOID:331 0 0.047
amyotrophic lateral sclerosis DOID:332 0 0.047
neurodegenerative disease DOID:1289 0 0.047
nervous system disease DOID:863 0 0.047
myelofibrosis DOID:4971 0 0.046
cell type cancer DOID:0050687 0 0.045
melanoma DOID:1909 0 0.045
greig cephalopolysyndactyly syndrome DOID:14761 0 0.043
bone development disease DOID:0080006 0 0.043
Human
bone disease DOID:0080001 0 0.043
Human
acrocephalosyndactylia DOID:12960 0 0.043
dysostosis DOID:1934 0 0.043
Human
synostosis DOID:11971 0 0.043
lymphoma DOID:0060058 0 0.042
tuberous sclerosis DOID:13515 0 0.039