Drosophila melanogaster

70 known processes

Chd1 (Dmel_CG3733)

Chromodomain-helicase-DNA-binding protein 1

(Aliases: CG3733,CHD1,DmCHD1,Dmel\CG3733,dCHD1,l(2)23Cd,CHD-1,chd1)

Chd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male pronucleus assembly GO:0035039 6 0.933
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.814
fertilization GO:0009566 26 0.775
regulation of gene expression epigenetic GO:0040029 128 0.704
negative regulation of gene expression epigenetic GO:0045814 77 0.630
chromatin remodeling GO:0006338 72 0.582
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.557
negative regulation of rna biosynthetic process GO:1902679 240 0.538
sperm chromatin decondensation GO:0035041 5 0.497
regulation of chromatin silencing GO:0031935 36 0.479
negative regulation of cellular biosynthetic process GO:0031327 277 0.467
negative regulation of nucleic acid templated transcription GO:1903507 240 0.466
negative regulation of chromatin silencing GO:0031936 9 0.457
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.436
negative regulation of transcription dna templated GO:0045892 237 0.408
negative regulation of biosynthetic process GO:0009890 277 0.334
chromosome organization GO:0051276 360 0.318
cell cell signaling involved in cell fate commitment GO:0045168 210 0.286
negative regulation of gene expression GO:0010629 387 0.261
chromatin silencing GO:0006342 76 0.235
chromatin modification GO:0016568 147 0.217
chromatin organization GO:0006325 207 0.213
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.193
negative regulation of cellular metabolic process GO:0031324 382 0.183
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.165
gene silencing GO:0016458 138 0.164
organelle assembly GO:0070925 198 0.163
negative regulation of rna metabolic process GO:0051253 251 0.159
histone h4 k16 acetylation GO:0043984 4 0.157
nucleus organization GO:0006997 45 0.141
dosage compensation GO:0007549 16 0.137
cellular protein modification process GO:0006464 438 0.121
dna packaging GO:0006323 91 0.119
single fertilization GO:0007338 24 0.118
chromatin assembly or disassembly GO:0006333 52 0.118
regulation of intracellular signal transduction GO:1902531 236 0.118
regulation of gene silencing GO:0060968 63 0.115
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.112
heterochromatin organization GO:0070828 25 0.106
compound eye development GO:0048749 307 0.103
regulation of small gtpase mediated signal transduction GO:0051056 93 0.099
ras protein signal transduction GO:0007265 88 0.096
regulation of ras protein signal transduction GO:0046578 93 0.091
small gtpase mediated signal transduction GO:0007264 88 0.078
regulation of dna metabolic process GO:0051052 34 0.073
mrna metabolic process GO:0016071 124 0.071
histone exchange GO:0043486 21 0.070
lateral inhibition GO:0046331 206 0.068
protein modification process GO:0036211 438 0.066
leg disc development GO:0035218 92 0.065
purine nucleoside triphosphate catabolic process GO:0009146 108 0.064
organelle fission GO:0048285 340 0.062
regulation of cellular catabolic process GO:0031329 157 0.059
dna metabolic process GO:0006259 227 0.057
intracellular signal transduction GO:0035556 300 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.055
regulation of rho protein signal transduction GO:0035023 20 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.054
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
aromatic compound catabolic process GO:0019439 166 0.049
protein localization GO:0008104 284 0.047
regulation of organelle organization GO:0033043 196 0.044
regionalization GO:0003002 416 0.043
rho protein signal transduction GO:0007266 14 0.043
actin cytoskeleton organization GO:0030036 206 0.042
leg disc morphogenesis GO:0007478 80 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
catabolic process GO:0009056 409 0.042
phosphorylation GO:0016310 294 0.041
negative regulation of cellular component organization GO:0051129 108 0.040
synapse organization GO:0050808 196 0.040
female meiotic division GO:0007143 70 0.039
spindle assembly involved in mitosis GO:0090307 50 0.037
body morphogenesis GO:0010171 2 0.037
nucleosome organization GO:0034728 59 0.034
apoptotic process GO:0006915 159 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.033
protein phosphorylation GO:0006468 169 0.033
embryo development ending in birth or egg hatching GO:0009792 152 0.033
nucleobase containing compound catabolic process GO:0034655 165 0.032
spindle assembly GO:0051225 80 0.031
histone modification GO:0016570 106 0.030
positive regulation of dna metabolic process GO:0051054 12 0.030
purine ribonucleotide catabolic process GO:0009154 109 0.028
protein acetylation GO:0006473 39 0.028
dna conformation change GO:0071103 105 0.027
imaginal disc derived leg morphogenesis GO:0007480 80 0.026
regulation of catabolic process GO:0009894 170 0.026
mitotic nuclear division GO:0007067 213 0.026
cellular macromolecule localization GO:0070727 220 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
regulation of rho gtpase activity GO:0032319 20 0.026
wing disc morphogenesis GO:0007472 344 0.025
sex determination GO:0007530 18 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.025
phagocytosis GO:0006909 215 0.025
cell projection assembly GO:0030031 94 0.025
purine nucleoside metabolic process GO:0042278 127 0.025
multi multicellular organism process GO:0044706 123 0.024
cell division GO:0051301 248 0.024
heterocycle catabolic process GO:0046700 166 0.023
cellular component disassembly GO:0022411 46 0.023
amine metabolic process GO:0009308 12 0.023
cellular catabolic process GO:0044248 372 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.023
cellular nitrogen compound catabolic process GO:0044270 165 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
nucleoside triphosphate metabolic process GO:0009141 120 0.022
positive regulation of rna metabolic process GO:0051254 271 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.021
regulation of purine nucleotide metabolic process GO:1900542 62 0.021
covalent chromatin modification GO:0016569 106 0.021
atp dependent chromatin remodeling GO:0043044 22 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
localization of cell GO:0051674 257 0.019
internal protein amino acid acetylation GO:0006475 38 0.019
gonad development GO:0008406 50 0.019
positive regulation of gene expression epigenetic GO:0045815 16 0.019
molting cycle GO:0042303 56 0.018
histone h4 k20 methylation GO:0034770 4 0.018
positive regulation of cellular component organization GO:0051130 156 0.018
molting cycle chitin based cuticle GO:0007591 56 0.018
digestive tract development GO:0048565 149 0.017
nucleoside catabolic process GO:0009164 112 0.017
spermatogenesis GO:0007283 200 0.017
purine containing compound metabolic process GO:0072521 155 0.017
cellular response to oxidative stress GO:0034599 28 0.017
spindle organization GO:0007051 253 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
peptidyl amino acid modification GO:0018193 105 0.017
regulation of histone modification GO:0031056 20 0.017
sensory organ morphogenesis GO:0090596 260 0.017
mitotic spindle organization GO:0007052 220 0.016
regulation of chromatin modification GO:1903308 28 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
nuclear division GO:0000280 332 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
regulation of sister chromatid cohesion GO:0007063 2 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
eye development GO:0001654 323 0.016
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.016
heterochromatin assembly GO:0031507 13 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
organic substance catabolic process GO:1901575 308 0.015
purine containing compound catabolic process GO:0072523 112 0.015
negative regulation of nervous system development GO:0051961 92 0.015
appendage development GO:0048736 401 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.014
negative regulation of ras protein signal transduction GO:0046580 13 0.014
macromolecular complex assembly GO:0065003 256 0.014
cellular amine metabolic process GO:0044106 12 0.014
imaginal disc pattern formation GO:0007447 91 0.014
protein glycosylation GO:0006486 32 0.014
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.014
protein catabolic process GO:0030163 101 0.014
cellular protein complex assembly GO:0043623 71 0.013
regulation of catalytic activity GO:0050790 185 0.013
regulation of ras gtpase activity GO:0032318 38 0.013
regulation of chromosome organization GO:0033044 64 0.013
internal peptidyl lysine acetylation GO:0018393 38 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
actin filament based process GO:0030029 220 0.013
single organism cellular localization GO:1902580 180 0.013
regulation of programmed cell death GO:0043067 152 0.013
regulation of protein localization GO:0032880 76 0.013
negative regulation of signal transduction GO:0009968 206 0.013
regulation of nucleotide catabolic process GO:0030811 48 0.013
histone methylation GO:0016571 40 0.013
meiosis ii GO:0007135 23 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
wing disc pattern formation GO:0035222 66 0.013
muscle structure development GO:0061061 224 0.013
chromosome segregation GO:0007059 157 0.012
salivary gland development GO:0007431 162 0.012
establishment of tissue polarity GO:0007164 87 0.012
regulation of hydrolase activity GO:0051336 97 0.012
cellular response to ionizing radiation GO:0071479 15 0.012
histone acetylation GO:0016573 38 0.012
regulation of rac protein signal transduction GO:0035020 3 0.012
growth GO:0040007 359 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
compound eye morphogenesis GO:0001745 249 0.012
organonitrogen compound metabolic process GO:1901564 318 0.012
reproductive system development GO:0061458 74 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
histone h4 acetylation GO:0043967 13 0.012
neuromuscular junction development GO:0007528 149 0.012
guanosine containing compound metabolic process GO:1901068 74 0.011
jnk cascade GO:0007254 50 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
protein complex biogenesis GO:0070271 201 0.011
larval development GO:0002164 104 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
mapk cascade GO:0000165 107 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
telomere organization GO:0032200 21 0.011
peptidyl threonine modification GO:0018210 3 0.011
cell proliferation GO:0008283 299 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
regulation of molecular function GO:0065009 217 0.011
response to biotic stimulus GO:0009607 294 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
regulation of cell projection organization GO:0031344 92 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
cell death GO:0008219 279 0.010
nucleotide catabolic process GO:0009166 109 0.010
telomere maintenance GO:0000723 21 0.010
dna repair GO:0006281 54 0.010
positive regulation of gtp catabolic process GO:0033126 43 0.010
positive regulation of gene expression GO:0010628 290 0.010
regulation of gtp catabolic process GO:0033124 44 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
nucleoside metabolic process GO:0009116 127 0.010

Chd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
cancer DOID:162 0 0.019