Drosophila melanogaster

73 known processes

Eaat1 (Dmel_CG3747)

Excitatory amino acid transporter 1

(Aliases: CG3747,AF001784,Dglt-1,dEaat1,EAAT,Dmel\CG3747,dEAAT1,Dglut-1,dEAAT)

Eaat1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.988
locomotory behavior GO:0007626 176 0.976
synaptic transmission GO:0007268 288 0.930
sensory perception of chemical stimulus GO:0007606 116 0.873
regulation of synaptic transmission GO:0050804 69 0.678
regulation of synapse structure and activity GO:0050803 128 0.630
transmembrane transport GO:0055085 139 0.559
response to mechanical stimulus GO:0009612 28 0.463
morphogenesis of an epithelium GO:0002009 276 0.449
cell migration GO:0016477 238 0.397
adult locomotory behavior GO:0008344 76 0.389
localization of cell GO:0051674 257 0.387
regulation of synaptic activity GO:0060025 9 0.330
sensory perception GO:0007600 196 0.317
cell cell signaling involved in cell fate commitment GO:0045168 210 0.314
regulation of neurotransmitter levels GO:0001505 38 0.261
negative regulation of cellular metabolic process GO:0031324 382 0.241
synapse assembly GO:0007416 143 0.225
adult behavior GO:0030534 137 0.217
axonogenesis GO:0007409 290 0.201
larval locomotory behavior GO:0008345 27 0.196
synapse organization GO:0050808 196 0.193
regulation of nervous system development GO:0051960 248 0.184
nucleobase containing small molecule metabolic process GO:0055086 174 0.183
regulation of neurogenesis GO:0050767 158 0.172
axon development GO:0061564 297 0.169
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.167
head development GO:0060322 135 0.151
actin filament based process GO:0030029 220 0.147
feeding behavior GO:0007631 50 0.146
cation transmembrane transport GO:0098655 88 0.145
tissue morphogenesis GO:0048729 297 0.136
macromolecular complex assembly GO:0065003 256 0.134
central nervous system development GO:0007417 201 0.130
flight behavior GO:0007629 26 0.129
synaptic vesicle transport GO:0048489 50 0.127
cellular response to abiotic stimulus GO:0071214 58 0.126
neurotransmitter transport GO:0006836 37 0.119
detection of stimulus GO:0051606 156 0.119
mating behavior GO:0007617 106 0.118
single organism biosynthetic process GO:0044711 206 0.113
eye development GO:0001654 323 0.113
cellular response to endogenous stimulus GO:0071495 80 0.106
organonitrogen compound metabolic process GO:1901564 318 0.105
purine containing compound metabolic process GO:0072521 155 0.104
cellular response to oxygen containing compound GO:1901701 79 0.102
cell death GO:0008219 279 0.099
organophosphate metabolic process GO:0019637 195 0.099
establishment of organelle localization GO:0051656 122 0.097
regulation of multicellular organismal development GO:2000026 414 0.095
regulation of organelle organization GO:0033043 196 0.093
small molecule metabolic process GO:0044281 305 0.090
detection of abiotic stimulus GO:0009582 66 0.089
cell motility GO:0048870 251 0.088
regulation of behavior GO:0050795 75 0.087
response to radiation GO:0009314 155 0.087
circadian rhythm GO:0007623 105 0.084
death GO:0016265 284 0.083
purine nucleotide biosynthetic process GO:0006164 29 0.082
regulation of multi organism process GO:0043900 131 0.081
reproductive behavior GO:0019098 122 0.079
carbohydrate derivative metabolic process GO:1901135 217 0.078
cell proliferation GO:0008283 299 0.077
organonitrogen compound biosynthetic process GO:1901566 117 0.076
response to light stimulus GO:0009416 124 0.074
learning GO:0007612 75 0.074
cellular protein modification process GO:0006464 438 0.069
cellular response to external stimulus GO:0071496 66 0.069
rhythmic process GO:0048511 106 0.068
membrane organization GO:0061024 112 0.067
lateral inhibition GO:0046331 206 0.065
catabolic process GO:0009056 409 0.064
programmed cell death GO:0012501 257 0.064
establishment of localization in cell GO:0051649 402 0.063
neurological system process GO:0050877 358 0.062
chromatin organization GO:0006325 207 0.062
purine nucleotide metabolic process GO:0006163 146 0.062
ameboidal type cell migration GO:0001667 151 0.061
developmental growth GO:0048589 280 0.060
regulation of phosphate metabolic process GO:0019220 210 0.060
multi organism reproductive behavior GO:0044705 121 0.060
organic substance transport GO:0071702 257 0.059
multi multicellular organism process GO:0044706 123 0.059
catechol containing compound biosynthetic process GO:0009713 3 0.059
organic substance catabolic process GO:1901575 308 0.058
purine ribonucleotide metabolic process GO:0009150 145 0.058
protein modification process GO:0036211 438 0.056
cellular response to chemical stimulus GO:0070887 199 0.055
actin filament based movement GO:0030048 26 0.054
oocyte development GO:0048599 124 0.054
wing disc morphogenesis GO:0007472 344 0.054
intracellular signal transduction GO:0035556 300 0.053
cellular catabolic process GO:0044248 372 0.053
negative regulation of response to stimulus GO:0048585 258 0.052
ethanolamine containing compound metabolic process GO:0042439 4 0.051
aging GO:0007568 143 0.051
response to temperature stimulus GO:0009266 106 0.051
chaeta development GO:0022416 97 0.050
nucleoside phosphate metabolic process GO:0006753 162 0.050
ribonucleotide metabolic process GO:0009259 145 0.049
response to abiotic stimulus GO:0009628 341 0.046
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.046
neuromuscular junction development GO:0007528 149 0.045
chromatin modification GO:0016568 147 0.045
body morphogenesis GO:0010171 2 0.045
protein complex assembly GO:0006461 200 0.045
nitrogen compound transport GO:0071705 85 0.045
carbohydrate derivative biosynthetic process GO:1901137 85 0.044
oocyte differentiation GO:0009994 145 0.044
larval development GO:0002164 104 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.043
cellular potassium ion transport GO:0071804 18 0.043
male courtship behavior GO:0008049 63 0.043
neurotransmitter secretion GO:0007269 35 0.042
organelle localization GO:0051640 148 0.041
kidney development GO:0001822 3 0.041
cognition GO:0050890 141 0.040
ion transmembrane transport GO:0034220 122 0.040
establishment of vesicle localization GO:0051650 51 0.039
nucleotide metabolic process GO:0009117 161 0.039
forebrain development GO:0030900 2 0.039
response to inorganic substance GO:0010035 44 0.038
purine containing compound biosynthetic process GO:0072522 30 0.038
eye morphogenesis GO:0048592 260 0.037
axon target recognition GO:0007412 16 0.037
negative regulation of multicellular organismal process GO:0051241 142 0.037
inorganic cation transmembrane transport GO:0098662 61 0.037
single organism membrane organization GO:0044802 93 0.037
regulation of cell differentiation GO:0045595 302 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
histone modification GO:0016570 106 0.035
negative regulation of biosynthetic process GO:0009890 277 0.035
amine metabolic process GO:0009308 12 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.034
cell recognition GO:0008037 102 0.034
regulation of apoptotic process GO:0042981 130 0.034
neural precursor cell proliferation GO:0061351 75 0.034
oxidation reduction process GO:0055114 123 0.034
photoreceptor cell differentiation GO:0046530 170 0.034
ribose phosphate metabolic process GO:0019693 145 0.033
signal release GO:0023061 49 0.033
apoptotic process GO:0006915 159 0.032
axon guidance GO:0007411 233 0.032
phosphorylation GO:0016310 294 0.032
actin cytoskeleton organization GO:0030036 206 0.032
establishment or maintenance of cell polarity GO:0007163 167 0.031
negative regulation of signaling GO:0023057 219 0.031
organic anion transport GO:0015711 28 0.031
positive regulation of response to stimulus GO:0048584 323 0.030
organelle fission GO:0048285 340 0.030
growth GO:0040007 359 0.030
positive regulation of nervous system development GO:0051962 69 0.029
purine ribonucleoside metabolic process GO:0046128 127 0.029
cellular response to organic cyclic compound GO:0071407 32 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.029
eye photoreceptor cell differentiation GO:0001754 145 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
regulation of membrane potential GO:0042391 35 0.028
multicellular organismal reproductive behavior GO:0033057 110 0.028
response to organic substance GO:0010033 284 0.028
positive regulation of cellular component organization GO:0051130 156 0.028
developmental cell growth GO:0048588 52 0.028
regulation of protein modification process GO:0031399 112 0.028
response to external biotic stimulus GO:0043207 293 0.027
cellular response to mechanical stimulus GO:0071260 2 0.027
cellular macromolecule localization GO:0070727 220 0.027
neuromuscular synaptic transmission GO:0007274 67 0.027
brain development GO:0007420 120 0.027
organonitrogen compound catabolic process GO:1901565 128 0.027
regulation of synapse organization GO:0050807 110 0.026
negative regulation of cellular component organization GO:0051129 108 0.026
homeostatic process GO:0042592 199 0.026
notch signaling pathway GO:0007219 120 0.025
catecholamine biosynthetic process GO:0042423 3 0.025
ion transport GO:0006811 145 0.025
cellular response to inorganic substance GO:0071241 8 0.025
nuclear division GO:0000280 332 0.025
mechanosensory behavior GO:0007638 12 0.025
nucleoside phosphate biosynthetic process GO:1901293 34 0.025
microtubule organizing center organization GO:0031023 168 0.025
epiboly GO:0090504 2 0.025
circulatory system process GO:0003013 37 0.024
response to biotic stimulus GO:0009607 294 0.024
detection of external stimulus GO:0009581 66 0.024
multicellular organismal aging GO:0010259 140 0.024
secretion by cell GO:0032940 101 0.023
protein phosphorylation GO:0006468 169 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
eye antennal disc development GO:0035214 60 0.022
morphogenesis of a polarized epithelium GO:0001738 93 0.022
camera type eye development GO:0043010 4 0.022
cellular response to organic substance GO:0071310 132 0.022
neuron recognition GO:0008038 101 0.022
response to alcohol GO:0097305 95 0.022
cellular macromolecular complex assembly GO:0034622 153 0.022
establishment of protein localization GO:0045184 163 0.022
response to wounding GO:0009611 94 0.021
cellular amine metabolic process GO:0044106 12 0.021
purine nucleoside metabolic process GO:0042278 127 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
regulation of catabolic process GO:0009894 170 0.021
regulation of feeding behavior GO:0060259 16 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
potassium ion transport GO:0006813 20 0.021
carboxylic acid transport GO:0046942 18 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
compound eye morphogenesis GO:0001745 249 0.021
negative regulation of multi organism process GO:0043901 29 0.020
cell maturation GO:0048469 144 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
extrinsic apoptotic signaling pathway GO:0097191 1 0.020
single organism membrane fusion GO:0044801 42 0.020
protein complex biogenesis GO:0070271 201 0.020
negative regulation of cell communication GO:0010648 223 0.020
ribonucleoside metabolic process GO:0009119 127 0.019
regulation of neurotransmitter secretion GO:0046928 14 0.019
sensory organ morphogenesis GO:0090596 260 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
organic hydroxy compound biosynthetic process GO:1901617 21 0.019
regulation of protein metabolic process GO:0051246 256 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
regionalization GO:0003002 416 0.019
appendage development GO:0048736 401 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
organophosphate biosynthetic process GO:0090407 46 0.019
anion transport GO:0006820 41 0.019
organelle assembly GO:0070925 198 0.019
cellular response to organonitrogen compound GO:0071417 36 0.018
regulation of transport GO:0051049 181 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
monovalent inorganic cation transport GO:0015672 40 0.018
learning or memory GO:0007611 141 0.018
negative regulation of rna metabolic process GO:0051253 251 0.017
regulation of proteasomal protein catabolic process GO:0061136 39 0.017
secretion GO:0046903 109 0.017
negative regulation of peptide hormone secretion GO:0090278 1 0.017
water homeostasis GO:0030104 3 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
centrosome cycle GO:0007098 137 0.017
anatomical structure homeostasis GO:0060249 97 0.017
spinal cord development GO:0021510 1 0.017
membrane fusion GO:0061025 42 0.017
regulation of ion transmembrane transport GO:0034765 27 0.017
stem cell development GO:0048864 79 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.016
macromolecule methylation GO:0043414 45 0.016
small molecule catabolic process GO:0044282 21 0.016
energy derivation by oxidation of organic compounds GO:0015980 32 0.016
regulation of developmental growth GO:0048638 174 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
cyclic nucleotide biosynthetic process GO:0009190 25 0.016
sensory perception of pain GO:0019233 4 0.016
chromosome organization GO:0051276 360 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
regulation of response to stress GO:0080134 200 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
organelle fusion GO:0048284 46 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
response to extracellular stimulus GO:0009991 116 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
ribonucleotide biosynthetic process GO:0009260 28 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
immune system process GO:0002376 347 0.015
purine ribonucleotide biosynthetic process GO:0009152 28 0.015
positive regulation of molecular function GO:0044093 136 0.015
single organism carbohydrate metabolic process GO:0044723 72 0.014
vesicle mediated transport GO:0016192 381 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
heterocycle catabolic process GO:0046700 166 0.014
cyclic purine nucleotide metabolic process GO:0052652 25 0.014
response to drug GO:0042493 17 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
larval behavior GO:0030537 42 0.014
multi organism behavior GO:0051705 175 0.014
response to alkaloid GO:0043279 26 0.014
lipid metabolic process GO:0006629 121 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
organic acid metabolic process GO:0006082 103 0.014
regulation of cell maturation GO:1903429 27 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
mitochondrion organization GO:0007005 65 0.014
covalent chromatin modification GO:0016569 106 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of protein catabolic process GO:0042176 55 0.014
regulation of nucleotide metabolic process GO:0006140 62 0.014
endocytosis GO:0006897 310 0.014
biological adhesion GO:0022610 138 0.014
alcohol metabolic process GO:0006066 25 0.013
protein methylation GO:0006479 43 0.013
neuroblast proliferation GO:0007405 74 0.013
cellular response to hormone stimulus GO:0032870 44 0.013
gland morphogenesis GO:0022612 145 0.013
protein kinase a signaling GO:0010737 2 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
molting cycle chitin based cuticle GO:0007591 56 0.013
courtship behavior GO:0007619 68 0.013
cellular respiration GO:0045333 26 0.013
immune response GO:0006955 246 0.013
instar larval development GO:0002168 55 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
male mating behavior GO:0060179 70 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
negative regulation of developmental process GO:0051093 201 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
neuromuscular process GO:0050905 21 0.012
neuron fate commitment GO:0048663 50 0.012
detection of light stimulus GO:0009583 58 0.012
cell adhesion GO:0007155 136 0.012
positive regulation of signal transduction GO:0009967 223 0.012
chemotaxis GO:0006935 249 0.012
circulatory system development GO:0072359 82 0.012
regulation of chromatin modification GO:1903308 28 0.012
multicellular organismal movement GO:0050879 3 0.012
response to metal ion GO:0010038 23 0.012
male courtship behavior veined wing generated song production GO:0045433 20 0.012
response to nutrient levels GO:0031667 114 0.012
salivary gland morphogenesis GO:0007435 145 0.012
telencephalon development GO:0021537 2 0.012
response to starvation GO:0042594 97 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
macromolecule catabolic process GO:0009057 161 0.012
defense response GO:0006952 300 0.012
regulation of reproductive process GO:2000241 54 0.012
cellular protein localization GO:0034613 160 0.012
wound healing GO:0042060 75 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
methylation GO:0032259 47 0.012
regulation of cellular response to stress GO:0080135 89 0.012
response to endogenous stimulus GO:0009719 119 0.012
regulation of nucleotide biosynthetic process GO:0030808 14 0.011
blood circulation GO:0008015 26 0.011
chemosensory behavior GO:0007635 106 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
vesicle localization GO:0051648 55 0.011
neurotransmitter receptor metabolic process GO:0045213 3 0.011
protein localization GO:0008104 284 0.011
camp metabolic process GO:0046058 19 0.011
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.011
positive regulation of transport GO:0051050 92 0.011
ribose phosphate biosynthetic process GO:0046390 28 0.011
olfactory learning GO:0008355 56 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
nucleoside metabolic process GO:0009116 127 0.011
mating GO:0007618 120 0.011
epithelium migration GO:0090132 148 0.011
actin filament organization GO:0007015 126 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
response to growth factor GO:0070848 31 0.011
response to nitrogen compound GO:1901698 90 0.010
intracellular mrna localization GO:0008298 66 0.010
microtubule polymerization or depolymerization GO:0031109 39 0.010
negative regulation of gene expression GO:0010629 387 0.010
regulation of transmembrane transporter activity GO:0022898 6 0.010
response to pain GO:0048265 3 0.010
epithelial cell differentiation GO:0030855 322 0.010
positive regulation of synaptic transmission GO:0050806 15 0.010
cellular ketone metabolic process GO:0042180 24 0.010
circadian behavior GO:0048512 76 0.010

Eaat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.038
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
liddle syndrome DOID:0050477 0 0.015
renal tubular transport disease DOID:447 0 0.015
kidney disease DOID:557 0 0.015
urinary system disease DOID:18 0 0.015
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010