Drosophila melanogaster

17 known processes

Aldh (Dmel_CG3752)

Aldehyde dehydrogenase

(Aliases: ACDH,Dmel\CG3752,CG3752,146084_at,ALDH)

Aldh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to oxidative stress GO:0006979 86 0.442
catabolic process GO:0009056 409 0.351
Yeast
cellular response to oxidative stress GO:0034599 28 0.344
single organism biosynthetic process GO:0044711 206 0.282
Yeast
small molecule metabolic process GO:0044281 305 0.245
Yeast
carboxylic acid metabolic process GO:0019752 92 0.210
Yeast
cellular aldehyde metabolic process GO:0006081 10 0.176
response to reactive oxygen species GO:0000302 24 0.168
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.160
cellular response to reactive oxygen species GO:0034614 14 0.160
acetaldehyde metabolic process GO:0006117 5 0.144
response to metal ion GO:0010038 23 0.144
response to oxygen radical GO:0000305 3 0.129
response to organophosphorus GO:0046683 2 0.127
negative regulation of biosynthetic process GO:0009890 277 0.125
pyridine nucleotide metabolic process GO:0019362 2 0.113
Yeast
single organism catabolic process GO:0044712 228 0.107
cellular response to chemical stimulus GO:0070887 199 0.100
sulfur compound metabolic process GO:0006790 59 0.095
response to inorganic substance GO:0010035 44 0.091
organic substance catabolic process GO:1901575 308 0.087
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.086
Yeast
response to starvation GO:0042594 97 0.085
single organism behavior GO:0044708 391 0.085
homeostatic process GO:0042592 199 0.078
single organism carbohydrate metabolic process GO:0044723 72 0.078
organonitrogen compound metabolic process GO:1901564 318 0.076
Yeast
forebrain development GO:0030900 2 0.076
cellular response to extracellular stimulus GO:0031668 64 0.076
organic acid metabolic process GO:0006082 103 0.069
Yeast
determination of adult lifespan GO:0008340 137 0.068
nicotinamide nucleotide metabolic process GO:0046496 2 0.068
Yeast
cellular catabolic process GO:0044248 372 0.067
response to abiotic stimulus GO:0009628 341 0.065
monocarboxylic acid metabolic process GO:0032787 29 0.063
Yeast
cellular response to hydrogen peroxide GO:0070301 7 0.063
appendage morphogenesis GO:0035107 397 0.060
ion transport GO:0006811 145 0.060
carbohydrate metabolic process GO:0005975 82 0.055
cellular response to dna damage stimulus GO:0006974 223 0.054
oxoacid metabolic process GO:0043436 103 0.054
Yeast
salivary gland development GO:0007431 162 0.054
organophosphate metabolic process GO:0019637 195 0.051
Yeast
histolysis GO:0007559 102 0.050
alpha amino acid metabolic process GO:1901605 20 0.050
oxidoreduction coenzyme metabolic process GO:0006733 2 0.050
Yeast
immune response GO:0006955 246 0.049
cellular lipid metabolic process GO:0044255 83 0.049
aging GO:0007568 143 0.048
paracrine signaling GO:0038001 7 0.044
cellular response to oxygen containing compound GO:1901701 79 0.044
response to extracellular stimulus GO:0009991 116 0.043
hydrogen peroxide catabolic process GO:0042744 6 0.043
cell redox homeostasis GO:0045454 5 0.043
post embryonic appendage morphogenesis GO:0035120 385 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
steroid catabolic process GO:0006706 1 0.041
multicellular organismal aging GO:0010259 140 0.041
thioester metabolic process GO:0035383 3 0.040
cellular response to external stimulus GO:0071496 66 0.040
response to nutrient levels GO:0031667 114 0.039
wing disc morphogenesis GO:0007472 344 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.038
response to oxygen containing compound GO:1901700 200 0.037
intracellular signal transduction GO:0035556 300 0.036
gland development GO:0048732 191 0.036
positive regulation of signaling GO:0023056 243 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
lipid metabolic process GO:0006629 121 0.035
response to ethanol GO:0045471 59 0.034
response to biotic stimulus GO:0009607 294 0.033
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.033
regulation of cell cycle GO:0051726 291 0.033
fatty acid metabolic process GO:0006631 20 0.033
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.033
immune system process GO:0002376 347 0.032
acyl coa metabolic process GO:0006637 3 0.032
small molecule catabolic process GO:0044282 21 0.032
exocrine system development GO:0035272 162 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
Yeast
brain development GO:0007420 120 0.031
autophagic cell death GO:0048102 83 0.031
cell aging GO:0007569 2 0.030
age dependent response to oxidative stress GO:0001306 3 0.030
appendage development GO:0048736 401 0.030
neurological system process GO:0050877 358 0.030
spermatid development GO:0007286 98 0.029
response to hydrogen peroxide GO:0042542 11 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
regulation of response to oxidative stress GO:1902882 4 0.028
cellular amino acid metabolic process GO:0006520 61 0.028
Yeast
gland morphogenesis GO:0022612 145 0.028
cellular response to organic substance GO:0071310 132 0.028
organic cyclic compound catabolic process GO:1901361 168 0.027
tissue death GO:0016271 102 0.027
pyridine containing compound metabolic process GO:0072524 3 0.027
Yeast
spermatogenesis GO:0007283 200 0.027
adult locomotory behavior GO:0008344 76 0.027
developmental programmed cell death GO:0010623 138 0.027
telencephalon development GO:0021537 2 0.027
death GO:0016265 284 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
programmed cell death GO:0012501 257 0.026
sex differentiation GO:0007548 81 0.026
organophosphate biosynthetic process GO:0090407 46 0.026
positive regulation of signal transduction GO:0009967 223 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
zinc ion homeostasis GO:0055069 6 0.025
nucleotide metabolic process GO:0009117 161 0.025
Yeast
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
negative regulation of gene expression GO:0010629 387 0.025
larval development GO:0002164 104 0.025
cellular carbohydrate metabolic process GO:0044262 22 0.025
positive regulation of cell communication GO:0010647 250 0.024
transition metal ion homeostasis GO:0055076 17 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
lateral inhibition GO:0046331 206 0.024
adult behavior GO:0030534 137 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.023
negative regulation of growth GO:0045926 84 0.023
oxidation reduction process GO:0055114 123 0.023
response to other organism GO:0051707 293 0.023
salivary gland histolysis GO:0035070 88 0.023
response to superoxide GO:0000303 3 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
response to lipopolysaccharide GO:0032496 4 0.021
positive regulation of apoptotic signaling pathway GO:2001235 4 0.021
regulation of growth GO:0040008 233 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
Yeast
skin development GO:0043588 65 0.021
cellular response to organonitrogen compound GO:0071417 36 0.021
response to endogenous stimulus GO:0009719 119 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.020
pentose metabolic process GO:0019321 1 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
peptide metabolic process GO:0006518 80 0.019
age dependent general metabolic decline GO:0007571 3 0.019
regulation of intracellular signal transduction GO:1902531 236 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
regulation of mrna metabolic process GO:1903311 72 0.018
double strand break repair GO:0006302 26 0.018
regulation of cellular response to oxidative stress GO:1900407 4 0.018
ribose phosphate biosynthetic process GO:0046390 28 0.018
connective tissue development GO:0061448 3 0.018
negative regulation of developmental process GO:0051093 201 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
rna splicing via transesterification reactions GO:0000375 73 0.017
cellular response to starvation GO:0009267 61 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
regulation of catabolic process GO:0009894 170 0.017
regionalization GO:0003002 416 0.017
response to heat GO:0009408 63 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
mrna metabolic process GO:0016071 124 0.017
cognition GO:0050890 141 0.016
jak stat cascade GO:0007259 49 0.016
response to organic substance GO:0010033 284 0.016
generation of precursor metabolites and energy GO:0006091 42 0.016
g protein coupled receptor signaling pathway GO:0007186 136 0.016
lipid biosynthetic process GO:0008610 46 0.016
mrna processing GO:0006397 104 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of mrna processing GO:0050684 71 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
carboxylic acid transport GO:0046942 18 0.015
response to external biotic stimulus GO:0043207 293 0.015
cellular response to inorganic substance GO:0071241 8 0.015
protein modification process GO:0036211 438 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of cell proliferation GO:0042127 163 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
dendrite morphogenesis GO:0048813 199 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of developmental growth GO:0048638 174 0.015
chemical homeostasis GO:0048878 92 0.014
dendrite development GO:0016358 204 0.014
cellular polysaccharide metabolic process GO:0044264 11 0.014
syncytium formation GO:0006949 43 0.014
cation homeostasis GO:0055080 51 0.014
autophagy GO:0006914 108 0.014
defense response to bacterium GO:0042742 178 0.014
cell type specific apoptotic process GO:0097285 38 0.013
chaeta development GO:0022416 97 0.013
dna repair GO:0006281 54 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
defense response GO:0006952 300 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
carboxylic acid catabolic process GO:0046395 16 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
regulation of immune system process GO:0002682 176 0.013
reproductive structure development GO:0048608 74 0.013
regulation of autophagy GO:0010506 62 0.013
organic acid catabolic process GO:0016054 16 0.013
response to calcium ion GO:0051592 1 0.013
androgen metabolic process GO:0008209 1 0.013
positive regulation of developmental growth GO:0048639 62 0.013
macromolecule catabolic process GO:0009057 161 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
ribonucleotide biosynthetic process GO:0009260 28 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
establishment of localization in cell GO:0051649 402 0.012
membrane organization GO:0061024 112 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
negative regulation of cell cycle GO:0045786 116 0.012
salivary gland morphogenesis GO:0007435 145 0.012
nuclear import GO:0051170 51 0.012
regulation of membrane potential GO:0042391 35 0.012
epidermal cell differentiation GO:0009913 51 0.012
nucleoside phosphate biosynthetic process GO:1901293 34 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
cellular response to hormone stimulus GO:0032870 44 0.012
male sex differentiation GO:0046661 25 0.012
cell growth GO:0016049 108 0.012
dna metabolic process GO:0006259 227 0.012
myoblast fusion GO:0007520 43 0.012
positive regulation of developmental process GO:0051094 143 0.012
regulation of programmed cell death GO:0043067 152 0.011
regulation of steroid metabolic process GO:0019218 2 0.011
negative regulation of immune system process GO:0002683 50 0.011
intracellular receptor signaling pathway GO:0030522 19 0.011
positive regulation of gene expression GO:0010628 290 0.011
response to bacterium GO:0009617 198 0.011
small molecule biosynthetic process GO:0044283 37 0.011
Yeast
imaginal disc pattern formation GO:0007447 91 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
Yeast
endocytosis GO:0006897 310 0.011
central nervous system development GO:0007417 201 0.011
male gamete generation GO:0048232 201 0.011
response to organic cyclic compound GO:0014070 89 0.011
developmental growth GO:0048589 280 0.011
response to copper ion GO:0046688 4 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
ribonucleoside biosynthetic process GO:0042455 3 0.011
taxis GO:0042330 304 0.011
amine metabolic process GO:0009308 12 0.011
Yeast
nucleoside metabolic process GO:0009116 127 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
metal ion homeostasis GO:0055065 44 0.011
rna processing GO:0006396 147 0.010
neuronal action potential GO:0019228 10 0.010
regulation of molecular function GO:0065009 217 0.010
learning GO:0007612 75 0.010
action potential GO:0001508 13 0.010
cell cycle checkpoint GO:0000075 95 0.010
aromatic compound catabolic process GO:0019439 166 0.010
regulation of protein metabolic process GO:0051246 256 0.010
locomotory behavior GO:0007626 176 0.010
regulation of apoptotic process GO:0042981 130 0.010
multi organism behavior GO:0051705 175 0.010
wound healing GO:0042060 75 0.010

Aldh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.083
inherited metabolic disorder DOID:655 0 0.083
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016