Drosophila melanogaster

50 known processes

Vha68-2 (Dmel_CG3762)

CG3762 gene product from transcript CG3762-RA

(Aliases: l(2)01510,vha68-2,Dmel\CG3762,CG3762,vha67-3,l(2)s4214,V-ATPase)

Vha68-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ph reduction GO:0045851 7 0.999
regulation of ph GO:0006885 7 0.993
vacuolar acidification GO:0007035 4 0.983
cation transport GO:0006812 110 0.752
Zebrafish
regulation of cellular ph GO:0030641 7 0.728
ion transport GO:0006811 145 0.712
Zebrafish
cellular monovalent inorganic cation homeostasis GO:0030004 7 0.644
chemical homeostasis GO:0048878 92 0.476
small molecule metabolic process GO:0044281 305 0.453
cation homeostasis GO:0055080 51 0.423
establishment of localization in cell GO:0051649 402 0.396
inorganic cation transmembrane transport GO:0098662 61 0.388
Zebrafish
negative regulation of biosynthetic process GO:0009890 277 0.387
retina development in camera type eye GO:0060041 4 0.372
ion homeostasis GO:0050801 55 0.328
ion transmembrane transport GO:0034220 122 0.323
Zebrafish
monovalent inorganic cation transport GO:0015672 40 0.316
Zebrafish
intracellular transport GO:0046907 228 0.315
camera type eye development GO:0043010 4 0.266
negative regulation of cellular metabolic process GO:0031324 382 0.265
single organism intracellular transport GO:1902582 207 0.249
inorganic ion transmembrane transport GO:0098660 73 0.243
Zebrafish
intracellular ph reduction GO:0051452 7 0.199
endocytosis GO:0006897 310 0.199
Worm
organonitrogen compound metabolic process GO:1901564 318 0.192
homeostatic process GO:0042592 199 0.169
central nervous system development GO:0007417 201 0.169
embryo development ending in birth or egg hatching GO:0009792 152 0.149
Worm
single organism catabolic process GO:0044712 228 0.148
eye development GO:0001654 323 0.146
cellular cation homeostasis GO:0030003 38 0.141
larval development GO:0002164 104 0.140
Worm
protein transport GO:0015031 155 0.137
glycosyl compound metabolic process GO:1901657 127 0.115
cellular ion homeostasis GO:0006873 39 0.115
glycosyl compound catabolic process GO:1901658 112 0.112
rna localization GO:0006403 115 0.108
organic substance transport GO:0071702 257 0.107
notch signaling pathway GO:0007219 120 0.103
Fly
ribonucleoside metabolic process GO:0009119 127 0.102
kidney development GO:0001822 3 0.098
organophosphate metabolic process GO:0019637 195 0.093
protein targeting to nucleus GO:0044744 51 0.092
response to abiotic stimulus GO:0009628 341 0.091
Zebrafish Fly
oxoacid metabolic process GO:0043436 103 0.087
nucleotide metabolic process GO:0009117 161 0.085
single organism cellular localization GO:1902580 180 0.084
ribonucleotide metabolic process GO:0009259 145 0.083
purine ribonucleoside metabolic process GO:0046128 127 0.083
monovalent inorganic cation homeostasis GO:0055067 7 0.082
negative regulation of gene expression GO:0010629 387 0.082
vesicle mediated transport GO:0016192 381 0.081
Worm
cellular protein localization GO:0034613 160 0.081
carboxylic acid metabolic process GO:0019752 92 0.080
catabolic process GO:0009056 409 0.079
cellular chemical homeostasis GO:0055082 40 0.079
purine ribonucleotide metabolic process GO:0009150 145 0.078
organic substance catabolic process GO:1901575 308 0.077
regulation of multicellular organismal development GO:2000026 414 0.077
programmed cell death GO:0012501 257 0.075
Worm
pigmentation GO:0043473 75 0.071
regulation of localization GO:0032879 275 0.071
cation transmembrane transport GO:0098655 88 0.071
Zebrafish
metal ion homeostasis GO:0055065 44 0.070
Zebrafish
cellular homeostasis GO:0019725 80 0.070
growth GO:0040007 359 0.070
enzyme linked receptor protein signaling pathway GO:0007167 179 0.067
cell proliferation GO:0008283 299 0.067
positive regulation of signaling GO:0023056 243 0.067
protein import into nucleus GO:0006606 51 0.062
nucleoside metabolic process GO:0009116 127 0.062
regulation of cell death GO:0010941 173 0.060
carbohydrate derivative metabolic process GO:1901135 217 0.057
protein localization GO:0008104 284 0.056
purine nucleoside metabolic process GO:0042278 127 0.055
spindle organization GO:0007051 253 0.054
positive regulation of response to stimulus GO:0048584 323 0.053
heterocycle catabolic process GO:0046700 166 0.052
cellular metal ion homeostasis GO:0006875 31 0.052
Zebrafish
protein import GO:0017038 55 0.051
cell adhesion GO:0007155 136 0.051
cellular ketone metabolic process GO:0042180 24 0.050
lipid localization GO:0010876 54 0.048
purine nucleotide metabolic process GO:0006163 146 0.048
atp metabolic process GO:0046034 49 0.047
nuclear transport GO:0051169 72 0.046
endomembrane system organization GO:0010256 119 0.046
nuclear import GO:0051170 51 0.046
sensory organ morphogenesis GO:0090596 260 0.045
cellular response to decreased oxygen levels GO:0036294 30 0.045
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.044
aging GO:0007568 143 0.043
organic acid metabolic process GO:0006082 103 0.042
brain development GO:0007420 120 0.042
aromatic compound catabolic process GO:0019439 166 0.042
maintenance of location GO:0051235 73 0.041
body morphogenesis GO:0010171 2 0.040
cellular component assembly involved in morphogenesis GO:0010927 151 0.039
proteolysis GO:0006508 192 0.039
striated muscle myosin thick filament assembly GO:0071688 3 0.039
regulation of notch signaling pathway GO:0008593 100 0.039
Fly
regulation of response to stress GO:0080134 200 0.039
purine ribonucleoside catabolic process GO:0046130 112 0.038
cellular pigmentation GO:0033059 12 0.038
tube morphogenesis GO:0035239 191 0.037
purine nucleotide catabolic process GO:0006195 109 0.037
tube development GO:0035295 244 0.037
regulation of cellular localization GO:0060341 136 0.037
establishment of protein localization GO:0045184 163 0.037
pigment granule organization GO:0048753 12 0.037
cellular macromolecule localization GO:0070727 220 0.037
regulation of transport GO:0051049 181 0.036
transition metal ion transport GO:0000041 16 0.036
transcription from rna polymerase ii promoter GO:0006366 368 0.035
positive regulation of cell communication GO:0010647 250 0.033
nucleoside catabolic process GO:0009164 112 0.033
ribonucleoside monophosphate metabolic process GO:0009161 51 0.033
purine containing compound metabolic process GO:0072521 155 0.033
peptide hormone processing GO:0016486 2 0.032
phagocytosis engulfment GO:0006911 11 0.032
cellular catabolic process GO:0044248 372 0.031
regulation of hormone levels GO:0010817 40 0.031
negative regulation of response to stimulus GO:0048585 258 0.031
metal ion transport GO:0030001 74 0.030
gastrulation with mouth forming first GO:0001703 36 0.030
response to decreased oxygen levels GO:0036293 58 0.030
Fly
transmembrane transport GO:0055085 139 0.030
Zebrafish
head development GO:0060322 135 0.029
hormone metabolic process GO:0042445 33 0.028
positive regulation of transport GO:0051050 92 0.028
cellular amino acid metabolic process GO:0006520 61 0.028
spindle assembly GO:0051225 80 0.028
hair cell differentiation GO:0035315 47 0.028
purine nucleoside triphosphate catabolic process GO:0009146 108 0.026
multicellular organismal aging GO:0010259 140 0.026
embryonic morphogenesis GO:0048598 206 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
organic hydroxy compound biosynthetic process GO:1901617 21 0.024
establishment of protein localization to organelle GO:0072594 62 0.024
spindle assembly involved in mitosis GO:0090307 50 0.024
cytoplasmic transport GO:0016482 130 0.024
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
response to wounding GO:0009611 94 0.024
membrane organization GO:0061024 112 0.023
hydrogen transport GO:0006818 7 0.023
Zebrafish
nucleocytoplasmic transport GO:0006913 72 0.023
organophosphate catabolic process GO:0046434 112 0.023
regulation of cell adhesion GO:0030155 27 0.023
organonitrogen compound biosynthetic process GO:1901566 117 0.023
negative regulation of cell development GO:0010721 62 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
regulation of programmed cell death GO:0043067 152 0.023
phagocytosis GO:0006909 215 0.022
response to light stimulus GO:0009416 124 0.022
positive regulation of cell death GO:0010942 69 0.022
single organism cell adhesion GO:0098602 47 0.022
response to oxygen levels GO:0070482 59 0.021
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.021
renal tubule development GO:0061326 64 0.021
syncytium formation by plasma membrane fusion GO:0000768 43 0.021
regulation of molecular function GO:0065009 217 0.020
protein localization to nucleus GO:0034504 55 0.020
single organism nuclear import GO:1902593 51 0.020
anion transport GO:0006820 41 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
sensory perception of sound GO:0007605 56 0.020
regulation of intracellular transport GO:0032386 64 0.019
compound eye development GO:0048749 307 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
cellular response to oxygen levels GO:0071453 30 0.019
Fly
regulation of cell differentiation GO:0045595 302 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
purine nucleoside catabolic process GO:0006152 112 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
negative regulation of nervous system development GO:0051961 92 0.018
response to copper ion GO:0046688 4 0.018
urogenital system development GO:0001655 72 0.018
mitotic spindle organization GO:0007052 220 0.018
response to organic substance GO:0010033 284 0.018
eye morphogenesis GO:0048592 260 0.018
immune response GO:0006955 246 0.017
single organism membrane organization GO:0044802 93 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
phosphorylation GO:0016310 294 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
negative regulation of cell differentiation GO:0045596 143 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
intracellular protein transport GO:0006886 104 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
intracellular signal transduction GO:0035556 300 0.016
negative regulation of signaling GO:0023057 219 0.016
ventral furrow formation GO:0007370 17 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
Fly
cellular macromolecular complex assembly GO:0034622 153 0.015
negative regulation of neurogenesis GO:0050768 53 0.015
regulation of microtubule cytoskeleton organization GO:0070507 41 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
death GO:0016265 284 0.014
Worm
purine ribonucleotide catabolic process GO:0009154 109 0.014
negative regulation of epithelial cell proliferation GO:0050680 4 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
cell death GO:0008219 279 0.014
Worm
negative regulation of signal transduction GO:0009968 206 0.014
single organismal cell cell adhesion GO:0016337 45 0.014
molting cycle GO:0042303 56 0.014
cell aging GO:0007569 2 0.014
nucleic acid transport GO:0050657 46 0.013
regulation of hemocyte proliferation GO:0035206 37 0.013
protein targeting GO:0006605 64 0.013
regulation of apoptotic process GO:0042981 130 0.013
protein complex biogenesis GO:0070271 201 0.013
establishment of rna localization GO:0051236 47 0.013
apoptotic process GO:0006915 159 0.013
Worm
acyl coa metabolic process GO:0006637 3 0.013
endosomal transport GO:0016197 44 0.013
biological adhesion GO:0022610 138 0.013
digestive tract morphogenesis GO:0048546 127 0.013
immune system process GO:0002376 347 0.013
purine containing compound catabolic process GO:0072523 112 0.013
olfactory behavior GO:0042048 97 0.013
organelle assembly GO:0070925 198 0.013
regulation of immune system process GO:0002682 176 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.013
nitrogen compound transport GO:0071705 85 0.013
rna transport GO:0050658 46 0.012
basement membrane organization GO:0071711 10 0.012
regulation of hydrolase activity GO:0051336 97 0.012
positive regulation of intracellular transport GO:0032388 42 0.012
centrosome organization GO:0051297 163 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
wound healing GO:0042060 75 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
positive regulation of binding GO:0051099 4 0.012
gastrulation GO:0007369 70 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
stem cell differentiation GO:0048863 117 0.012
glial cell differentiation GO:0010001 35 0.012
membrane invagination GO:0010324 11 0.012
protein complex assembly GO:0006461 200 0.012
single organism biosynthetic process GO:0044711 206 0.011
localization of cell GO:0051674 257 0.011
regulation of catalytic activity GO:0050790 185 0.011
hydrogen ion transmembrane transport GO:1902600 5 0.011
Zebrafish
protein localization to organelle GO:0033365 82 0.011
mesenchymal cell development GO:0014031 1 0.011
cellular response to hypoxia GO:0071456 28 0.011
Fly
receptor mediated endocytosis GO:0006898 21 0.011
Worm
cellular lipid metabolic process GO:0044255 83 0.010
cellular response to organic substance GO:0071310 132 0.010
mrna processing GO:0006397 104 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
regulation of growth GO:0040008 233 0.010
positive regulation of signal transduction GO:0009967 223 0.010
protein modification process GO:0036211 438 0.010
regulation of cellular response to stress GO:0080135 89 0.010

Vha68-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.190
urinary system disease DOID:18 0 0.190
renal tubular transport disease DOID:447 0 0.075
kidney disease DOID:557 0 0.075
disease of metabolism DOID:0014667 0 0.023
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.015