Drosophila melanogaster

70 known processes

Efr (Dmel_CG3774)

ER GDP-fucose transporter

(Aliases: CG3774,Dmel\CG3774)

Efr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to mercury ion GO:0046689 3 0.124
organic hydroxy compound metabolic process GO:1901615 83 0.105
response to radiation GO:0009314 155 0.093
small molecule metabolic process GO:0044281 305 0.093
programmed cell death GO:0012501 257 0.091
response to organic substance GO:0010033 284 0.091
defense response GO:0006952 300 0.090
cell death GO:0008219 279 0.087
oxoacid metabolic process GO:0043436 103 0.079
response to organophosphorus GO:0046683 2 0.072
organonitrogen compound metabolic process GO:1901564 318 0.072
cellular catabolic process GO:0044248 372 0.062
death GO:0016265 284 0.062
tissue migration GO:0090130 155 0.061
organic substance catabolic process GO:1901575 308 0.060
central nervous system development GO:0007417 201 0.060
innate immune response GO:0045087 144 0.058
regulation of apoptotic process GO:0042981 130 0.057
apoptotic process GO:0006915 159 0.057
wing disc morphogenesis GO:0007472 344 0.056
response to organic cyclic compound GO:0014070 89 0.052
regulation of programmed cell death GO:0043067 152 0.052
response to light stimulus GO:0009416 124 0.051
regulation of cell death GO:0010941 173 0.051
enzyme linked receptor protein signaling pathway GO:0007167 179 0.051
forebrain development GO:0030900 2 0.051
single organism catabolic process GO:0044712 228 0.049
protein complex assembly GO:0006461 200 0.046
epithelial cell migration GO:0010631 148 0.046
negative regulation of response to stimulus GO:0048585 258 0.046
response to external biotic stimulus GO:0043207 293 0.043
negative regulation of signaling GO:0023057 219 0.042
immune system process GO:0002376 347 0.041
negative regulation of signal transduction GO:0009968 206 0.040
cellular response to endogenous stimulus GO:0071495 80 0.039
negative regulation of cell communication GO:0010648 223 0.038
epithelium migration GO:0090132 148 0.038
telencephalon development GO:0021537 2 0.038
regionalization GO:0003002 416 0.037
imaginal disc derived appendage development GO:0048737 399 0.037
homeostatic process GO:0042592 199 0.037
kidney development GO:0001822 3 0.036
response to lipopolysaccharide GO:0032496 4 0.035
response to other organism GO:0051707 293 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.034
hormone catabolic process GO:0042447 3 0.034
dephosphorylation GO:0016311 51 0.034
positive regulation of cell motility GO:2000147 3 0.034
vesicle mediated transport GO:0016192 381 0.034
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
response to biotic stimulus GO:0009607 294 0.032
carboxylic acid metabolic process GO:0019752 92 0.032
protein complex biogenesis GO:0070271 201 0.032
cellular chemical homeostasis GO:0055082 40 0.032
transmembrane transport GO:0055085 139 0.032
response to endogenous stimulus GO:0009719 119 0.031
body morphogenesis GO:0010171 2 0.031
response to oxygen containing compound GO:1901700 200 0.030
cellular response to extracellular stimulus GO:0031668 64 0.030
single organism intracellular transport GO:1902582 207 0.030
appendage development GO:0048736 401 0.029
steroid catabolic process GO:0006706 1 0.029
positive regulation of cell migration GO:0030335 2 0.029
cellular ketone metabolic process GO:0042180 24 0.029
regulation of localization GO:0032879 275 0.028
localization of cell GO:0051674 257 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
axon development GO:0061564 297 0.028
organonitrogen compound biosynthetic process GO:1901566 117 0.028
anion transmembrane transport GO:0098656 26 0.027
secretion GO:0046903 109 0.027
positive regulation of signal transduction GO:0009967 223 0.027
ameboidal type cell migration GO:0001667 151 0.027
endocytosis GO:0006897 310 0.027
immune response GO:0006955 246 0.027
response to abiotic stimulus GO:0009628 341 0.027
determination of adult lifespan GO:0008340 137 0.027
positive regulation of cell communication GO:0010647 250 0.027
segmentation GO:0035282 207 0.027
macromolecular complex assembly GO:0065003 256 0.027
ion transmembrane transport GO:0034220 122 0.026
establishment of localization in cell GO:0051649 402 0.026
cellular aldehyde metabolic process GO:0006081 10 0.026
regulation of bmp signaling pathway GO:0030510 23 0.025
response to lithium ion GO:0010226 1 0.024
head development GO:0060322 135 0.024
androgen metabolic process GO:0008209 1 0.024
response to monosaccharide GO:0034284 4 0.024
response to starvation GO:0042594 97 0.024
negative regulation of programmed cell death GO:0043069 72 0.024
negative regulation of gene expression GO:0010629 387 0.024
chaeta development GO:0022416 97 0.024
heterocycle catabolic process GO:0046700 166 0.023
response to alcohol GO:0097305 95 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.023
respiratory system development GO:0060541 213 0.023
organic substance transport GO:0071702 257 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
positive regulation of signaling GO:0023056 243 0.022
cellular response to abiotic stimulus GO:0071214 58 0.022
protein localization GO:0008104 284 0.022
chemotaxis GO:0006935 249 0.022
l glutamate import GO:0051938 1 0.022
estrogen metabolic process GO:0008210 1 0.022
regulation of transport GO:0051049 181 0.022
protein transport GO:0015031 155 0.022
single organism behavior GO:0044708 391 0.022
catabolic process GO:0009056 409 0.021
intracellular transport GO:0046907 228 0.021
response to organonitrogen compound GO:0010243 75 0.021
connective tissue development GO:0061448 3 0.021
single organism cellular localization GO:1902580 180 0.021
organophosphate metabolic process GO:0019637 195 0.021
cellular lipid metabolic process GO:0044255 83 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
single organism biosynthetic process GO:0044711 206 0.021
growth GO:0040007 359 0.020
response to glucose GO:0009749 2 0.020
ovarian follicle cell development GO:0030707 248 0.020
cell migration GO:0016477 238 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
developmental growth GO:0048589 280 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
negative regulation of cell death GO:0060548 81 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
cellular macromolecule localization GO:0070727 220 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
organic acid metabolic process GO:0006082 103 0.019
appendage morphogenesis GO:0035107 397 0.019
regulation of reproductive process GO:2000241 54 0.019
aromatic compound catabolic process GO:0019439 166 0.019
secretion by cell GO:0032940 101 0.019
cellular response to carbohydrate stimulus GO:0071322 4 0.019
establishment of protein localization GO:0045184 163 0.019
regulation of cell cycle GO:0051726 291 0.019
oxidation reduction process GO:0055114 123 0.019
salivary gland morphogenesis GO:0007435 145 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
organophosphate catabolic process GO:0046434 112 0.019
cell motility GO:0048870 251 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
cellular protein localization GO:0034613 160 0.018
immune system development GO:0002520 57 0.018
anion homeostasis GO:0055081 3 0.018
negative regulation of insulin secretion GO:0046676 1 0.018
cellular response to organic substance GO:0071310 132 0.018
aging GO:0007568 143 0.018
cellular response to hexose stimulus GO:0071331 1 0.018
cellular response to monosaccharide stimulus GO:0071326 2 0.017
regulation of catalytic activity GO:0050790 185 0.017
neurological system process GO:0050877 358 0.017
hormone metabolic process GO:0042445 33 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
bmp signaling pathway GO:0030509 27 0.017
cellular response to hormone stimulus GO:0032870 44 0.017
cellular homeostasis GO:0019725 80 0.017
sensory perception of smell GO:0007608 80 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
cellular amine metabolic process GO:0044106 12 0.016
chemical homeostasis GO:0048878 92 0.016
camera type eye development GO:0043010 4 0.016
regulation of hormone levels GO:0010817 40 0.016
cellular response to external stimulus GO:0071496 66 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
negative regulation of apoptotic process GO:0043066 63 0.016
cellular response to radiation GO:0071478 52 0.016
axon guidance GO:0007411 233 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
response to bacterium GO:0009617 198 0.016
regulation of immune system process GO:0002682 176 0.016
negative regulation of peptide hormone secretion GO:0090278 1 0.015
defense response to other organism GO:0098542 225 0.015
phagocytosis GO:0006909 215 0.015
locomotor rhythm GO:0045475 56 0.015
inorganic cation transmembrane transport GO:0098662 61 0.015
actin cytoskeleton organization GO:0030036 206 0.015
carbohydrate metabolic process GO:0005975 82 0.015
compound eye development GO:0048749 307 0.015
epithelial cell development GO:0002064 274 0.015
imaginal disc derived wing vein specification GO:0007474 48 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
open tracheal system development GO:0007424 204 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
gland development GO:0048732 191 0.015
inorganic ion transmembrane transport GO:0098660 73 0.015
cellular response to organic cyclic compound GO:0071407 32 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
amine metabolic process GO:0009308 12 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
neuron projection guidance GO:0097485 241 0.014
cellular response to mechanical stimulus GO:0071260 2 0.014
brain development GO:0007420 120 0.014
epithelial cell differentiation GO:0030855 322 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.014
neuron recognition GO:0008038 101 0.014
purine containing compound transmembrane transport GO:0072530 5 0.014
regulation of blood circulation GO:1903522 21 0.014
regulation of multi organism process GO:0043900 131 0.014
cell proliferation GO:0008283 299 0.014
regulation of growth GO:0040008 233 0.014
embryonic axis specification GO:0000578 107 0.014
protein dephosphorylation GO:0006470 27 0.014
cell recognition GO:0008037 102 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
cation transport GO:0006812 110 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
regulation of immune response GO:0050776 118 0.013
multi multicellular organism process GO:0044706 123 0.013
embryonic pattern specification GO:0009880 174 0.013
axonogenesis GO:0007409 290 0.013
glycerolipid catabolic process GO:0046503 3 0.013
positive regulation of transport GO:0051050 92 0.013
response to nutrient levels GO:0031667 114 0.013
intracellular protein transport GO:0006886 104 0.013
response to wounding GO:0009611 94 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
multicellular organismal aging GO:0010259 140 0.013
regulation of cellular localization GO:0060341 136 0.013
regulation of response to stress GO:0080134 200 0.013
polyol biosynthetic process GO:0046173 3 0.013
nitrogen compound transport GO:0071705 85 0.013
regulation of developmental growth GO:0048638 174 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
eye development GO:0001654 323 0.013
endodermal cell differentiation GO:0035987 3 0.013
positive regulation of developmental process GO:0051094 143 0.013
regulation of anatomical structure size GO:0090066 163 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
response to inorganic substance GO:0010035 44 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
metal ion transport GO:0030001 74 0.012
regulation of protein metabolic process GO:0051246 256 0.012
organic hydroxy compound catabolic process GO:1901616 4 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
tripartite regional subdivision GO:0007351 103 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
response to hormone GO:0009725 45 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
embryonic morphogenesis GO:0048598 206 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
nucleoside metabolic process GO:0009116 127 0.012
cation transmembrane transport GO:0098655 88 0.012
eye antennal disc development GO:0035214 60 0.012
response to calcium ion GO:0051592 1 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.011
regulation of innate immune response GO:0045088 71 0.011
spermatogenesis GO:0007283 200 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
phosphorylation GO:0016310 294 0.011
vitamin biosynthetic process GO:0009110 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
lateral inhibition GO:0046331 206 0.011
ethanolamine containing compound metabolic process GO:0042439 4 0.011
border follicle cell migration GO:0007298 113 0.011
ion transport GO:0006811 145 0.011
synaptic target recognition GO:0008039 45 0.011
negative regulation of developmental process GO:0051093 201 0.011
actin filament based process GO:0030029 220 0.011
embryonic hindgut morphogenesis GO:0048619 48 0.011
negative regulation of peptide secretion GO:0002792 1 0.011
alcohol metabolic process GO:0006066 25 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
cholesterol homeostasis GO:0042632 3 0.011
cellular response to ionizing radiation GO:0071479 15 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
purine nucleoside biosynthetic process GO:0042451 3 0.011
protein localization to organelle GO:0033365 82 0.011
cellular response to nutrient levels GO:0031669 62 0.011
regulation of cell proliferation GO:0042127 163 0.011
peptidyl amino acid modification GO:0018193 105 0.010
response to hexose GO:0009746 3 0.010
regulation of cell differentiation GO:0045595 302 0.010
blastoderm segmentation GO:0007350 159 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
amine catabolic process GO:0009310 1 0.010
mitotic spindle organization GO:0007052 220 0.010
multicellular organism growth GO:0035264 46 0.010
potassium ion transport GO:0006813 20 0.010
sex differentiation GO:0007548 81 0.010
cell division GO:0051301 248 0.010
response to ketone GO:1901654 34 0.010
axis specification GO:0009798 167 0.010

Efr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
cardiovascular system disease DOID:1287 0 0.030
kidney disease DOID:557 0 0.019
urinary system disease DOID:18 0 0.019
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
hypertension DOID:10763 0 0.015
artery disease DOID:0050828 0 0.015
vascular disease DOID:178 0 0.015
lipid metabolism disorder DOID:3146 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
nervous system disease DOID:863 0 0.011
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010