Drosophila melanogaster

96 known processes

numb (Dmel_CG3779)

CG3779 gene product from transcript CG3779-RB

(Aliases: l(2)3235,numbs,dNumb,CG3779,l(2)s2201,Nb,l(2)03235,d-numb,Numb,Dmel\CG3779,N7-1,nb)

numb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric neuroblast division GO:0055059 33 1.000
asymmetric cell division GO:0008356 37 0.999
neuron projection guidance GO:0097485 241 0.996
axonogenesis GO:0007409 290 0.995
Mouse
taxis GO:0042330 304 0.993
neuroblast fate determination GO:0007400 12 0.992
malpighian tubule tip cell differentiation GO:0061382 9 0.991
chemotaxis GO:0006935 249 0.989
stem cell fate commitment GO:0048865 25 0.989
localization of cell GO:0051674 257 0.983
motor neuron axon guidance GO:0008045 58 0.979
embryonic morphogenesis GO:0048598 206 0.977
regulation of anatomical structure morphogenesis GO:0022603 242 0.967
Mouse Rat
cell fate determination GO:0001709 91 0.961
brain development GO:0007420 120 0.960
Mouse Fly
muscle cell differentiation GO:0042692 103 0.959
regulation of cell projection organization GO:0031344 92 0.946
Rat
negative regulation of signal transduction GO:0009968 206 0.940
Zebrafish Mouse
negative regulation of cell communication GO:0010648 223 0.929
Zebrafish Mouse
neuroblast fate commitment GO:0014017 19 0.912
positive regulation of cellular biosynthetic process GO:0031328 316 0.902
regulation of cell development GO:0060284 215 0.901
tissue morphogenesis GO:0048729 297 0.899
Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.897
regionalization GO:0003002 416 0.892
neuroblast differentiation GO:0014016 29 0.890
organelle assembly GO:0070925 198 0.880
regulation of multicellular organismal development GO:2000026 414 0.879
substrate dependent cell migration GO:0006929 3 0.874
regulation of neurogenesis GO:0050767 158 0.868
cellular protein modification process GO:0006464 438 0.863
organelle localization GO:0051640 148 0.834
chaeta development GO:0022416 97 0.829
cell adhesion GO:0007155 136 0.827
death GO:0016265 284 0.827
eye photoreceptor cell differentiation GO:0001754 145 0.826
regulation of nervous system development GO:0051960 248 0.816
neural precursor cell proliferation GO:0061351 75 0.814
axon guidance GO:0007411 233 0.809
synapse assembly GO:0007416 143 0.800
protein modification process GO:0036211 438 0.796
spermatid differentiation GO:0048515 114 0.794
synapse organization GO:0050808 196 0.778
regulation of cellular protein metabolic process GO:0032268 243 0.764
actin filament based process GO:0030029 220 0.751
neurological system process GO:0050877 358 0.730
axon development GO:0061564 297 0.729
Mouse
regulation of dendrite development GO:0050773 37 0.720
Rat
rna localization GO:0006403 115 0.719
regulation of protein metabolic process GO:0051246 256 0.707
actin cytoskeleton organization GO:0030036 206 0.665
cell motility GO:0048870 251 0.643
cell death GO:0008219 279 0.636
positive regulation of cell differentiation GO:0045597 64 0.627
Mouse Rat
regulation of cell cycle phase transition GO:1901987 130 0.604
regulation of cell cycle GO:0051726 291 0.601
regulation of protein modification process GO:0031399 112 0.597
asymmetric stem cell division GO:0098722 49 0.596
phosphorylation GO:0016310 294 0.588
regulation of anatomical structure size GO:0090066 163 0.576
biological adhesion GO:0022610 138 0.576
regulation of wnt signaling pathway GO:0030111 68 0.573
embryo development ending in birth or egg hatching GO:0009792 152 0.570
regulation of neuron projection development GO:0010975 69 0.567
Rat
positive regulation of nervous system development GO:0051962 69 0.562
Mouse Rat
cell migration GO:0016477 238 0.555
vesicle mediated transport GO:0016192 381 0.547
regulation of cell division GO:0051302 72 0.544
actin filament organization GO:0007015 126 0.528
protein phosphorylation GO:0006468 169 0.527
regulation of cellular amine metabolic process GO:0033238 3 0.522
gastrulation GO:0007369 70 0.522
cilium organization GO:0044782 41 0.497
regulation of cell cycle process GO:0010564 181 0.487
negative regulation of signaling GO:0023057 219 0.480
Zebrafish Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.477
Zebrafish
renal system development GO:0072001 72 0.474
neuroblast proliferation GO:0007405 74 0.463
regulation of phosphate metabolic process GO:0019220 210 0.461
endodermal cell fate commitment GO:0001711 3 0.450
centrosome cycle GO:0007098 137 0.431
cilium morphogenesis GO:0060271 39 0.426
response to abiotic stimulus GO:0009628 341 0.424
establishment or maintenance of cell polarity GO:0007163 167 0.418
cell cell signaling involved in cell fate commitment GO:0045168 210 0.414
stem cell differentiation GO:0048863 117 0.413
stem cell proliferation GO:0072089 88 0.407
cellular response to oxygen containing compound GO:1901701 79 0.405
negative regulation of cellular metabolic process GO:0031324 382 0.398
regulation of phosphorus metabolic process GO:0051174 210 0.395
cardiovascular system development GO:0072358 82 0.386
centriole assembly GO:0098534 24 0.382
regulation of molecular function GO:0065009 217 0.379
neuroblast division GO:0055057 35 0.374
positive regulation of molecular function GO:0044093 136 0.367
cardiac cell fate commitment GO:0060911 17 0.358
morphogenesis of an epithelium GO:0002009 276 0.356
Mouse
digestive system development GO:0055123 149 0.355
regulation of synapse assembly GO:0051963 94 0.353
positive regulation of response to stimulus GO:0048584 323 0.353
Worm
regulation of protein phosphorylation GO:0001932 64 0.350
epithelial cell differentiation GO:0030855 322 0.343
Mouse
single organism cellular localization GO:1902580 180 0.334
Human Worm
spermatid development GO:0007286 98 0.330
cell proliferation GO:0008283 299 0.328
positive regulation of rna metabolic process GO:0051254 271 0.322
centrosome organization GO:0051297 163 0.322
regulation of immune system process GO:0002682 176 0.322
programmed cell death GO:0012501 257 0.317
positive regulation of multicellular organismal process GO:0051240 143 0.314
Mouse Rat
dendrite development GO:0016358 204 0.310
Rat
mesoderm development GO:0007498 78 0.309
central nervous system development GO:0007417 201 0.300
Mouse Fly
macromolecular complex assembly GO:0065003 256 0.299
cognition GO:0050890 141 0.289
telencephalon development GO:0021537 2 0.289
Mouse
regulation of neuron differentiation GO:0045664 103 0.288
Rat
positive regulation of cell development GO:0010720 61 0.287
Mouse Rat
organ formation GO:0048645 39 0.285
actin polymerization or depolymerization GO:0008154 31 0.281
dendrite morphogenesis GO:0048813 199 0.280
Rat
stem cell fate determination GO:0048867 15 0.275
regulation of synapse structure and activity GO:0050803 128 0.273
positive regulation of proteolysis GO:0045862 52 0.271
protein modification by small protein conjugation GO:0032446 79 0.270
regulation of catalytic activity GO:0050790 185 0.264
urogenital system development GO:0001655 72 0.257
cell projection assembly GO:0030031 94 0.256
imaginal disc pattern formation GO:0007447 91 0.256
regulation of cytoskeleton organization GO:0051493 89 0.254
muscle organ development GO:0007517 127 0.253
intracellular signal transduction GO:0035556 300 0.253
apoptotic process GO:0006915 159 0.252
regulation of cell morphogenesis GO:0022604 163 0.251
Rat
positive regulation of developmental process GO:0051094 143 0.248
Mouse Rat
regulation of organelle organization GO:0033043 196 0.244
positive regulation of macromolecule metabolic process GO:0010604 405 0.242
wnt signaling pathway GO:0016055 98 0.242
regulation of cellular component size GO:0032535 98 0.240
regulation of cell differentiation GO:0045595 302 0.238
cell cell adhesion GO:0098609 26 0.237
negative regulation of developmental process GO:0051093 201 0.237
mesenchymal cell differentiation GO:0048762 1 0.233
response to radiation GO:0009314 155 0.233
cell recognition GO:0008037 102 0.233
male gamete generation GO:0048232 201 0.232
circulatory system development GO:0072359 82 0.230
cell cycle phase transition GO:0044770 140 0.224
notch signaling pathway GO:0007219 120 0.223
Zebrafish Mouse
endocytosis GO:0006897 310 0.223
phagocytosis GO:0006909 215 0.223
Fly
ameboidal type cell migration GO:0001667 151 0.220
neuronal stem cell division GO:0036445 35 0.217
organonitrogen compound metabolic process GO:1901564 318 0.217
cilium assembly GO:0042384 38 0.215
developmental maturation GO:0021700 172 0.215
Fly
regulation of dendrite morphogenesis GO:0048814 28 0.213
Rat
peptidyl tyrosine modification GO:0018212 24 0.213
regulation of growth GO:0040008 233 0.213
muscle structure development GO:0061061 224 0.212
camera type eye morphogenesis GO:0048593 2 0.211
wing disc morphogenesis GO:0007472 344 0.210
cellular amino acid metabolic process GO:0006520 61 0.209
negative regulation of mitotic cell cycle GO:0045930 109 0.205
positive regulation of biosynthetic process GO:0009891 316 0.202
regulation of apoptotic process GO:0042981 130 0.202
negative regulation of cell cycle GO:0045786 116 0.194
cellular amine metabolic process GO:0044106 12 0.192
somatic stem cell division GO:0048103 37 0.189
single organism cell adhesion GO:0098602 47 0.187
negative regulation of response to stimulus GO:0048585 258 0.186
Zebrafish Mouse
regulation of synapse organization GO:0050807 110 0.186
response to organic substance GO:0010033 284 0.184
Human
embryonic heart tube development GO:0035050 22 0.179
positive regulation of immune system process GO:0002684 68 0.179
formation of primary germ layer GO:0001704 24 0.178
hair cell differentiation GO:0035315 47 0.174
positive regulation of transcription dna templated GO:0045893 266 0.174
regulation of actin polymerization or depolymerization GO:0008064 27 0.174
photoreceptor cell differentiation GO:0046530 170 0.171
sensory perception GO:0007600 196 0.167
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.166
positive regulation of gliogenesis GO:0014015 5 0.164
imaginal disc derived wing morphogenesis GO:0007476 337 0.163
regulation of axonogenesis GO:0050770 32 0.162
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.160
protein ubiquitination GO:0016567 70 0.160
wnt signaling pathway involved in heart development GO:0003306 3 0.159
cardiocyte differentiation GO:0035051 29 0.159
positive regulation of rna biosynthetic process GO:1902680 266 0.158
protein complex assembly GO:0006461 200 0.155
formation of organ boundary GO:0010160 30 0.154
regulation of cellular ketone metabolic process GO:0010565 3 0.154
chaeta morphogenesis GO:0008407 42 0.153
positive regulation of cellular protein metabolic process GO:0032270 118 0.153
response to light stimulus GO:0009416 124 0.153
positive regulation of neurogenesis GO:0050769 41 0.152
Mouse Rat
regulation of embryonic development GO:0045995 68 0.150
eye photoreceptor cell development GO:0042462 81 0.149
digestive tract development GO:0048565 149 0.149
embryonic development via the syncytial blastoderm GO:0001700 148 0.149
regulation of protein kinase activity GO:0045859 51 0.148
positive regulation of gene expression GO:0010628 290 0.144
spermatogenesis GO:0007283 200 0.144
amine metabolic process GO:0009308 12 0.141
regulation of protein stability GO:0031647 43 0.140
cardiac muscle tissue development GO:0048738 9 0.140
establishment of planar polarity GO:0001736 87 0.138
mitotic spindle organization GO:0007052 220 0.136
forebrain development GO:0030900 2 0.134
Mouse
compound eye morphogenesis GO:0001745 249 0.133
embryonic pattern specification GO:0009880 174 0.133
response to nitrogen compound GO:1901698 90 0.132
protein targeting GO:0006605 64 0.131
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.127
cellular protein localization GO:0034613 160 0.127
Human Worm
hindbrain development GO:0030902 2 0.127
heart development GO:0007507 82 0.123
cellular ketone metabolic process GO:0042180 24 0.122
regulation of proteolysis GO:0030162 87 0.121
peripheral nervous system development GO:0007422 52 0.120
regulation of meiosis GO:0040020 3 0.118
malpighian tubule development GO:0072002 64 0.114
regulation of actin cytoskeleton organization GO:0032956 42 0.114
immune response GO:0006955 246 0.113
protein localization GO:0008104 284 0.113
striated muscle cell differentiation GO:0051146 90 0.112
cellular catabolic process GO:0044248 372 0.111
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.111
positive regulation of cell cycle GO:0045787 43 0.108
positive regulation of signal transduction GO:0009967 223 0.108
Worm
regulation of actin filament polymerization GO:0030833 25 0.105
activation of rac gtpase activity GO:0032863 3 0.105
protein modification by small protein conjugation or removal GO:0070647 106 0.099
negative regulation of neural precursor cell proliferation GO:2000178 27 0.099
photoreceptor cell development GO:0042461 96 0.099
regulation of transferase activity GO:0051338 58 0.098
immune system process GO:0002376 347 0.097
Zebrafish
negative regulation of organelle organization GO:0010639 56 0.097
mesenchymal cell development GO:0014031 1 0.097
regulation of response to stress GO:0080134 200 0.097
tube development GO:0035295 244 0.096
negative regulation of binding GO:0051100 5 0.095
proteolysis GO:0006508 192 0.094
positive regulation of cell motility GO:2000147 3 0.093
Human
regulation of immune response GO:0050776 118 0.092
reproductive system development GO:0061458 74 0.091
negative regulation of cell proliferation GO:0008285 69 0.091
cellular macromolecular complex assembly GO:0034622 153 0.090
regulation of actin filament length GO:0030832 27 0.090
positive regulation of cell cycle process GO:0090068 28 0.086
peptidyl tyrosine phosphorylation GO:0018108 24 0.086
regulation of phosphorylation GO:0042325 147 0.086
compound eye photoreceptor cell differentiation GO:0001751 140 0.085
digestive tract morphogenesis GO:0048546 127 0.084
neuron recognition GO:0008038 101 0.084
dorsal closure GO:0007391 79 0.084
negative regulation of synapse assembly GO:0051964 39 0.083
protein transport GO:0015031 155 0.083
Worm
regulation of cellular component movement GO:0051270 42 0.082
Human
cell division GO:0051301 248 0.081
negative regulation of gene expression GO:0010629 387 0.080
positive regulation of phagocytosis engulfment GO:0060100 1 0.080
regulation of canonical wnt signaling pathway GO:0060828 15 0.079
regulation of cell adhesion GO:0030155 27 0.079
regulation of cellular amino acid metabolic process GO:0006521 0 0.079
positive regulation of phosphorus metabolic process GO:0010562 139 0.077
regulation of mitotic cell cycle GO:0007346 190 0.077
organophosphate metabolic process GO:0019637 195 0.076
carbohydrate derivative metabolic process GO:1901135 217 0.076
enzyme linked receptor protein signaling pathway GO:0007167 179 0.075
Worm
glial cell differentiation GO:0010001 35 0.075
synaptic growth at neuromuscular junction GO:0051124 119 0.074
spindle organization GO:0007051 253 0.073
cellular component assembly involved in morphogenesis GO:0010927 151 0.073
stem cell fate specification GO:0048866 2 0.072
mitochondrial fission GO:0000266 8 0.072
regulation of immune effector process GO:0002697 52 0.071
locomotory behavior GO:0007626 176 0.070
regulation of establishment of planar polarity GO:0090175 22 0.070
small molecule metabolic process GO:0044281 305 0.070
imaginal disc derived wing hair organization GO:0035317 45 0.069
establishment of spindle localization GO:0051293 22 0.068
establishment of tissue polarity GO:0007164 87 0.067
regulation of programmed cell death GO:0043067 152 0.067
oocyte differentiation GO:0009994 145 0.067
epidermis development GO:0008544 65 0.065
ras protein signal transduction GO:0007265 88 0.064
nucleobase containing small molecule metabolic process GO:0055086 174 0.063
spindle assembly involved in male meiosis GO:0007053 5 0.062
prostaglandin biosynthetic process GO:0001516 1 0.062
cellular response to growth factor stimulus GO:0071363 30 0.061
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.061
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.059
positive regulation of phosphate metabolic process GO:0045937 139 0.058
rac protein signal transduction GO:0016601 3 0.058
positive regulation of catalytic activity GO:0043085 118 0.057
lamellipodium assembly GO:0030032 21 0.057
negative regulation of epithelial cell proliferation GO:0050680 4 0.056
ubiquitin dependent protein catabolic process GO:0006511 78 0.056
head development GO:0060322 135 0.056
Mouse Fly
r3 r4 cell differentiation GO:0048056 12 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.054
Worm
regulation of localization GO:0032879 275 0.052
positive regulation of nucleic acid templated transcription GO:1903508 266 0.052
regulation of response to external stimulus GO:0032101 115 0.051
oocyte microtubule cytoskeleton organization GO:0016325 35 0.051
modification dependent protein catabolic process GO:0019941 78 0.051
negative regulation of cellular protein metabolic process GO:0032269 85 0.051
organic acid metabolic process GO:0006082 103 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.050
positive regulation of phosphorylation GO:0042327 87 0.050
retinal ganglion cell axon guidance GO:0031290 12 0.049
anterior posterior pattern specification GO:0009952 136 0.049
response to nutrient levels GO:0031667 114 0.048
multicellular organismal aging GO:0010259 140 0.048
peptidyl amino acid modification GO:0018193 105 0.048
mitotic nuclear division GO:0007067 213 0.048
transcription from rna polymerase ii promoter GO:0006366 368 0.047
microtubule organizing center organization GO:0031023 168 0.047
development of primary sexual characteristics GO:0045137 50 0.047
positive regulation of protein metabolic process GO:0051247 128 0.047
endodermal cell differentiation GO:0035987 3 0.047
chorion containing eggshell formation GO:0007304 105 0.047
regulation of organ morphogenesis GO:2000027 78 0.046
Mouse
cortical actin cytoskeleton organization GO:0030866 24 0.046
positive regulation of immune response GO:0050778 63 0.046
male meiosis chromosome segregation GO:0007060 10 0.046
growth GO:0040007 359 0.046
regulation of cellular component biogenesis GO:0044087 201 0.045
regulation of glial cell differentiation GO:0045685 1 0.045
positive regulation of apoptotic process GO:0043065 47 0.044
connective tissue development GO:0061448 3 0.044
positive regulation of cell communication GO:0010647 250 0.044
Worm
canonical wnt signaling pathway GO:0060070 21 0.043
negative regulation of catalytic activity GO:0043086 42 0.043
blastoderm segmentation GO:0007350 159 0.043
positive regulation of protein modification process GO:0031401 58 0.043
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.043
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.042
regulation of actin filament based process GO:0032970 42 0.042
regulation of protein polymerization GO:0032271 28 0.042
cellular macromolecule localization GO:0070727 220 0.041
Human Worm
neuromuscular junction development GO:0007528 149 0.041
regulation of cell cell adhesion GO:0022407 21 0.041
negative regulation of protein metabolic process GO:0051248 85 0.040
regulation of apoptotic signaling pathway GO:2001233 10 0.040
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.040
embryonic organ development GO:0048568 50 0.039
endoderm formation GO:0001706 3 0.039
cellular component disassembly GO:0022411 46 0.039
cellular response to organonitrogen compound GO:0071417 36 0.039
eye development GO:0001654 323 0.038
positive regulation of chromatin silencing at telomere GO:0031940 2 0.038
mesenchyme development GO:0060485 9 0.038
body morphogenesis GO:0010171 2 0.038
receptor mediated endocytosis GO:0006898 21 0.037
regulation of cell proliferation GO:0042127 163 0.037
positive regulation of neuron differentiation GO:0045666 26 0.036
Rat
regulation of viral genome replication GO:0045069 4 0.036
regulation of developmental growth GO:0048638 174 0.036
specification of organ identity GO:0010092 3 0.036
negative regulation of cell death GO:0060548 81 0.035
developmental programmed cell death GO:0010623 138 0.035
homeostatic process GO:0042592 199 0.035
Zebrafish
negative regulation of rna metabolic process GO:0051253 251 0.035
mesoderm morphogenesis GO:0048332 22 0.034
regulation of microtubule based process GO:0032886 49 0.034
tissue death GO:0016271 102 0.034
regulation of stem cell proliferation GO:0072091 40 0.034
macromolecule catabolic process GO:0009057 161 0.034
spindle assembly GO:0051225 80 0.034
actin filament polymerization GO:0030041 27 0.034
activation of protein kinase activity GO:0032147 12 0.034
regulation of mitotic cell cycle phase transition GO:1901990 130 0.033
cytoplasmic transport GO:0016482 130 0.033
compound eye development GO:0048749 307 0.033
mitotic cell cycle phase transition GO:0044772 138 0.032
muscle tissue morphogenesis GO:0060415 2 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.032
negative regulation of cellular component organization GO:0051129 108 0.032
Human
positive regulation of transferase activity GO:0051347 26 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.031
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.031
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.031
response to oxygen containing compound GO:1901700 200 0.031
response to bacterium GO:0009617 198 0.031
camera type eye development GO:0043010 4 0.031
regulation of hemocyte proliferation GO:0035206 37 0.030
sex differentiation GO:0007548 81 0.030
establishment of mitotic spindle localization GO:0040001 17 0.030
epithelial cell development GO:0002064 274 0.030
membrane disassembly GO:0030397 4 0.029
negative regulation of nervous system development GO:0051961 92 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
gland morphogenesis GO:0022612 145 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
compound eye photoreceptor development GO:0042051 78 0.029
regulation of cytoplasmic transport GO:1903649 47 0.029
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.029
Rat
regulation of defense response GO:0031347 102 0.028
multi organism behavior GO:0051705 175 0.028
regulation of epithelial cell migration GO:0010632 12 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.028
Rat
epidermal cell differentiation GO:0009913 51 0.028
positive regulation of cellular component biogenesis GO:0044089 80 0.028
cell junction assembly GO:0034329 42 0.028
positive regulation of programmed cell death GO:0043068 62 0.027
lateral inhibition GO:0046331 206 0.027
tripartite regional subdivision GO:0007351 103 0.026
nuclear division GO:0000280 332 0.026
establishment of organelle localization GO:0051656 122 0.026
positive regulation of actin filament polymerization GO:0030838 11 0.026
reproductive structure development GO:0048608 74 0.026
detection of stimulus GO:0051606 156 0.025
regulation of r7 cell differentiation GO:0045676 15 0.025
wing disc dorsal ventral pattern formation GO:0048190 47 0.025
chromosome segregation GO:0007059 157 0.025
skin development GO:0043588 65 0.025
regulation of cell shape GO:0008360 113 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
regulation of protein localization GO:0032880 76 0.025
Human
circulatory system process GO:0003013 37 0.025
regulation of kinase activity GO:0043549 53 0.024
stem cell division GO:0017145 69 0.024
positive regulation of cell projection organization GO:0031346 29 0.024
Rat
posttranscriptional regulation of gene expression GO:0010608 145 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
blood circulation GO:0008015 26 0.024
regulation of transport GO:0051049 181 0.023
positive regulation of neuron apoptotic process GO:0043525 1 0.023
segmentation GO:0035282 207 0.023
skeletal muscle fiber development GO:0048741 3 0.023
meiotic nuclear division GO:0007126 151 0.023
protein polymerization GO:0051258 42 0.023
positive regulation of protein phosphorylation GO:0001934 34 0.023
defense response to bacterium GO:0042742 178 0.023
immune response regulating signaling pathway GO:0002764 2 0.023
lymph gland development GO:0048542 28 0.023
regulation of notch signaling pathway GO:0008593 100 0.022
Zebrafish Mouse
cellular protein complex assembly GO:0043623 71 0.022
regulation of cell size GO:0008361 63 0.022
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
detection of stimulus involved in sensory perception GO:0050906 92 0.022
meiotic cell cycle process GO:1903046 132 0.022
response to other organism GO:0051707 293 0.022
regulation of endocytosis GO:0030100 37 0.022
syncytium formation by plasma membrane fusion GO:0000768 43 0.022
anterior posterior axis specification embryo GO:0008595 103 0.021
antimicrobial peptide production GO:0002775 46 0.021
stem cell development GO:0048864 79 0.021
negative regulation of protein modification process GO:0031400 29 0.021
hemopoiesis GO:0030097 46 0.021
Zebrafish
positive regulation of cell migration GO:0030335 2 0.021
Human
positive regulation of cellular catabolic process GO:0031331 95 0.021
genitalia development GO:0048806 26 0.021
adherens junction organization GO:0034332 27 0.021
Mouse
immune system development GO:0002520 57 0.020
Zebrafish
protein complex biogenesis GO:0070271 201 0.020
response to ionizing radiation GO:0010212 32 0.020
multi multicellular organism process GO:0044706 123 0.020
left right pattern formation GO:0060972 1 0.020
cell fate commitment involved in pattern specification GO:0060581 31 0.020
positive regulation of cell proliferation GO:0008284 47 0.020
germarium derived female germ line cyst formation GO:0030727 42 0.019
negative chemotaxis GO:0050919 15 0.019
positive regulation of signaling GO:0023056 243 0.019
Worm
regulation of nucleotide metabolic process GO:0006140 62 0.019
regulation of cellular amide metabolic process GO:0034248 39 0.019
microtubule bundle formation GO:0001578 27 0.018
positive regulation of developmental growth GO:0048639 62 0.018
regulation of protein depolymerization GO:1901879 27 0.018
response to growth factor GO:0070848 31 0.018
regulation of cellular localization GO:0060341 136 0.018
Human
initiation of dorsal closure GO:0007392 12 0.018
neuronal action potential GO:0019228 10 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
regulation of asymmetric cell division GO:0009786 3 0.018
dendrite guidance GO:0070983 21 0.018
hindgut morphogenesis GO:0007442 58 0.018
response to organonitrogen compound GO:0010243 75 0.017
negative regulation of neurogenesis GO:0050768 53 0.017
embryonic hemopoiesis GO:0035162 26 0.017
Zebrafish
positive regulation of kinase activity GO:0033674 25 0.017
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
catabolic process GO:0009056 409 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
amnioserosa maintenance GO:0046665 5 0.017
single organism behavior GO:0044708 391 0.017
skeletal muscle organ development GO:0060538 48 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
cell migration involved in gastrulation GO:0042074 9 0.017

numb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.115
nervous system disease DOID:863 0 0.047