Drosophila melanogaster

444 known processes

N (Dmel_CG3936)

Notch

(Aliases: co,1.1,16-178,EG:163A10.2,Chp,spl,l(1)Ax,dNotch,16-55,swb,nd,anon-EST:Liang-1.12,CT13012,n[fah],Dmel\CG3936,fa,CG3936,Co,clone 1.12,l(1)N,EG:140G11.1,shd,l(1)3Cb,Ax,notch)

N biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 276 1.000
tissue morphogenesis GO:0048729 297 1.000
r7 cell differentiation GO:0045466 43 1.000
imaginal disc derived appendage morphogenesis GO:0035114 395 1.000
r3 r4 cell differentiation GO:0048056 12 1.000
ovarian follicle cell development GO:0030707 248 1.000
learning or memory GO:0007611 141 1.000
photoreceptor cell differentiation GO:0046530 170 1.000
columnar cuboidal epithelial cell differentiation GO:0002065 256 1.000
cell fate determination GO:0001709 91 1.000
regulation of notch signaling pathway GO:0008593 100 1.000
immune system process GO:0002376 347 1.000
negative regulation of multicellular organismal process GO:0051241 142 0.999
cell projection assembly GO:0030031 94 0.999
digestive tract development GO:0048565 149 0.999
negative regulation of cellular metabolic process GO:0031324 382 0.999
Mouse
establishment of planar polarity GO:0001736 87 0.998
cardiocyte differentiation GO:0035051 29 0.998
compound eye morphogenesis GO:0001745 249 0.998
crystal cell differentiation GO:0042688 7 0.998
r3 r4 cell fate commitment GO:0007464 10 0.998
eggshell formation GO:0030703 105 0.997
negative regulation of developmental process GO:0051093 201 0.997
cell fate specification GO:0001708 71 0.997
chorion containing eggshell formation GO:0007304 105 0.997
morphogenesis of a polarized epithelium GO:0001738 93 0.997
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.997
Mouse
establishment of ommatidial planar polarity GO:0042067 49 0.997
stem cell development GO:0048864 79 0.996
post embryonic appendage morphogenesis GO:0035120 385 0.996
cellular protein modification process GO:0006464 438 0.994
regulation of cellular component biogenesis GO:0044087 201 0.994
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.994
transcription from rna polymerase ii promoter GO:0006366 368 0.994
respiratory system development GO:0060541 213 0.994
germarium derived egg chamber formation GO:0007293 101 0.994
central nervous system development GO:0007417 201 0.994
Zebrafish Mouse Rat
positive regulation of neural precursor cell proliferation GO:2000179 8 0.993
Rat
embryonic organ development GO:0048568 50 0.993
epithelial cell type specification open tracheal system GO:0035153 11 0.993
forebrain development GO:0030900 2 0.992
Zebrafish Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.992
Mouse
eye morphogenesis GO:0048592 260 0.991
synaptic transmission GO:0007268 288 0.990
eggshell chorion assembly GO:0007306 66 0.989
establishment or maintenance of cell polarity GO:0007163 167 0.988
hemocyte differentiation GO:0042386 38 0.988
eye photoreceptor cell differentiation GO:0001754 145 0.987
multi organism behavior GO:0051705 175 0.986
Worm
regulation of cell proliferation GO:0042127 163 0.985
regulation of anatomical structure morphogenesis GO:0022603 242 0.985
epithelial cell development GO:0002064 274 0.984
dorsal appendage formation GO:0046843 47 0.984
digestive tract morphogenesis GO:0048546 127 0.983
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.983
nuclear division GO:0000280 332 0.982
Worm
gland development GO:0048732 191 0.982
negative regulation of biosynthetic process GO:0009890 277 0.982
Mouse
cardiovascular system development GO:0072358 82 0.981
tube development GO:0035295 244 0.980
stem cell differentiation GO:0048863 117 0.979
regulation of nervous system development GO:0051960 248 0.979
sensory organ morphogenesis GO:0090596 260 0.979
stem cell maintenance GO:0019827 67 0.978
columnar cuboidal epithelial cell development GO:0002066 249 0.978
organelle fission GO:0048285 340 0.977
Worm
embryonic morphogenesis GO:0048598 206 0.976
cell proliferation GO:0008283 299 0.976
regulation of stem cell proliferation GO:0072091 40 0.975
Rat
open tracheal system development GO:0007424 204 0.975
genital disc development GO:0035215 44 0.974
neurological system process GO:0050877 358 0.971
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.970
negative regulation of gene expression GO:0010629 387 0.969
positive regulation of nervous system development GO:0051962 69 0.969
Mouse Rat
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.968
Human Mouse
circulatory system development GO:0072359 82 0.968
ovarian follicle cell stalk formation GO:0030713 17 0.967
renal system development GO:0072001 72 0.967
renal tubule development GO:0061326 64 0.966
negative regulation of cell differentiation GO:0045596 143 0.964
response to organonitrogen compound GO:0010243 75 0.963
Mouse
pericardium morphogenesis GO:0003344 2 0.962
Mouse
neuron projection guidance GO:0097485 241 0.961
imaginal disc derived appendage development GO:0048737 399 0.959
cognition GO:0050890 141 0.957
negative regulation of nucleic acid templated transcription GO:1903507 240 0.956
Mouse
chemotaxis GO:0006935 249 0.953
heart field specification GO:0003128 0 0.951
axon guidance GO:0007411 233 0.950
neuronal stem cell maintenance GO:0097150 4 0.948
Human Zebrafish
heart induction GO:0003129 3 0.947
protein complex assembly GO:0006461 200 0.945
establishment of tissue polarity GO:0007164 87 0.943
regulation of cell morphogenesis GO:0022604 163 0.942
Human Mouse
notch signaling pathway GO:0007219 120 0.939
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.938
appendage morphogenesis GO:0035107 397 0.936
synapse assembly GO:0007416 143 0.936
single organism behavior GO:0044708 391 0.935
cell fate commitment involved in pattern specification GO:0060581 31 0.935
synapse organization GO:0050808 196 0.935
epithelial tube morphogenesis GO:0060562 88 0.934
regulation of molecular function GO:0065009 217 0.930
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.929
wing disc morphogenesis GO:0007472 344 0.928
epithelial cell differentiation GO:0030855 322 0.927
negative regulation of rna biosynthetic process GO:1902679 240 0.926
Mouse
wnt signaling pathway involved in heart development GO:0003306 3 0.923
regulation of glial cell differentiation GO:0045685 1 0.922
Mouse Rat
axon development GO:0061564 297 0.919
compound eye development GO:0048749 307 0.916
telencephalon development GO:0021537 2 0.912
negative regulation of neurogenesis GO:0050768 53 0.910
dendrite morphogenesis GO:0048813 199 0.907
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.907
regulation of multicellular organismal development GO:2000026 414 0.907
mesoderm development GO:0007498 78 0.906
regionalization GO:0003002 416 0.905
digestive system development GO:0055123 149 0.899
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.888
Mouse
brain development GO:0007420 120 0.887
Zebrafish Mouse Rat
regulation of neural precursor cell proliferation GO:2000177 35 0.886
Rat
kidney epithelium development GO:0072073 3 0.885
Mouse
organelle localization GO:0051640 148 0.883
response to nitrogen compound GO:1901698 90 0.882
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.881
Human Mouse
hemopoiesis GO:0030097 46 0.879
muscle cell differentiation GO:0042692 103 0.875
epithelium migration GO:0090132 148 0.874
regulation of cell cycle GO:0051726 291 0.874
regulation of dendrite morphogenesis GO:0048814 28 0.869
regulation of catabolic process GO:0009894 170 0.869
regulation of mitosis GO:0007088 56 0.863
defense response GO:0006952 300 0.862
Mouse
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.862
memory GO:0007613 94 0.861
regulation of heart morphogenesis GO:2000826 3 0.859
Mouse Rat
germ cell migration GO:0008354 43 0.859
regulation of neurogenesis GO:0050767 158 0.854
renal tubule morphogenesis GO:0061333 44 0.850
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.850
Mouse
dendrite regeneration GO:0031104 2 0.849
retinal ganglion cell axon guidance GO:0031290 12 0.847
phosphorylation GO:0016310 294 0.841
regulation of cardioblast cell fate specification GO:0042686 8 0.838
dorsal ventral pattern formation GO:0009953 133 0.838
dna metabolic process GO:0006259 227 0.837
actin filament bundle organization GO:0061572 28 0.825
regulation of growth GO:0040008 233 0.825
gland morphogenesis GO:0022612 145 0.824
Mouse
regulation of neuron projection development GO:0010975 69 0.822
regulation of cytoskeleton organization GO:0051493 89 0.821
motor neuron axon guidance GO:0008045 58 0.820
regulation of photoreceptor cell differentiation GO:0046532 34 0.815
immune system development GO:0002520 57 0.815
positive regulation of biosynthetic process GO:0009891 316 0.814
positive regulation of cell differentiation GO:0045597 64 0.813
Human Zebrafish Mouse Rat
cardioblast cell fate specification GO:0042685 9 0.810
morphogenesis of a branching structure GO:0001763 45 0.809
Mouse
organic substance catabolic process GO:1901575 308 0.804
photoreceptor cell fate commitment GO:0046552 41 0.802
regulation of cell division GO:0051302 72 0.801
Worm
cellular response to inorganic substance GO:0071241 8 0.799
negative regulation of nervous system development GO:0051961 92 0.789
multi multicellular organism process GO:0044706 123 0.778
Worm
regulation of cell differentiation GO:0045595 302 0.777
neuron fate commitment GO:0048663 50 0.776
Mouse
spindle organization GO:0007051 253 0.775
eye photoreceptor cell fate commitment GO:0042706 37 0.775
photoreceptor cell development GO:0042461 96 0.773
protein localization to organelle GO:0033365 82 0.772
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.771
positive regulation of cellular biosynthetic process GO:0031328 316 0.770
hair cell differentiation GO:0035315 47 0.769
Mouse
malpighian tubule tip cell differentiation GO:0061382 9 0.766
response to endogenous stimulus GO:0009719 119 0.765
Human Mouse Rat
neuroblast differentiation GO:0014016 29 0.764
morphogenesis of embryonic epithelium GO:0016331 94 0.763
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.761
head development GO:0060322 135 0.760
Zebrafish Mouse Rat
pericardium development GO:0060039 2 0.749
Mouse
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.749
urogenital system development GO:0001655 72 0.748
oocyte morphogenesis GO:0048601 3 0.745
nephron development GO:0072006 3 0.736
Mouse
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.732
developmental growth involved in morphogenesis GO:0060560 65 0.732
Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.732
Worm
cell division GO:0051301 248 0.728
Zebrafish Mouse Worm
positive regulation of developmental process GO:0051094 143 0.725
Human Zebrafish Mouse Rat
cellular component assembly involved in morphogenesis GO:0010927 151 0.722
positive regulation of cell proliferation GO:0008284 47 0.721
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.717
appendage development GO:0048736 401 0.715
ribose phosphate metabolic process GO:0019693 145 0.713
dorsal closure GO:0007391 79 0.710
olfactory behavior GO:0042048 97 0.704
response to organic substance GO:0010033 284 0.704
Human Mouse Rat
fusion cell fate specification GO:0035156 4 0.703
catabolic process GO:0009056 409 0.700
regulation of striated muscle tissue development GO:0016202 5 0.696
Human Mouse
positive regulation of ribosome biogenesis GO:0090070 3 0.694
regulation of cellular catabolic process GO:0031329 157 0.692
negative regulation of gene expression epigenetic GO:0045814 77 0.690
cellular catabolic process GO:0044248 372 0.689
regulation of cellular response to growth factor stimulus GO:0090287 13 0.687
positive regulation of rna biosynthetic process GO:1902680 266 0.685
purine ribonucleotide metabolic process GO:0009150 145 0.685
dorsal closure leading edge cell differentiation GO:0046663 2 0.684
protein modification process GO:0036211 438 0.683
compound eye photoreceptor fate commitment GO:0001752 36 0.679
regulation of cell cycle process GO:0010564 181 0.678
positive regulation of transcription dna templated GO:0045893 266 0.675
positive regulation of cell development GO:0010720 61 0.673
Human Mouse Rat
regulation of organelle organization GO:0033043 196 0.673
Worm
cuticle development GO:0042335 86 0.670
mitotic spindle organization GO:0007052 220 0.664
response to oxygen containing compound GO:1901700 200 0.662
Mouse Rat
organ induction GO:0001759 3 0.656
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.652
negative regulation of cell communication GO:0010648 223 0.650
Mouse
intracellular signal transduction GO:0035556 300 0.643
regulation of imaginal disc derived wing size GO:0044719 20 0.642
meiotic nuclear envelope disassembly GO:0051078 2 0.636
centrosome cycle GO:0007098 137 0.634
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.633
Mouse
bmp signaling pathway GO:0030509 27 0.625
Mouse
specification of organ identity GO:0010092 3 0.622
epithelial cell migration GO:0010631 148 0.622
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.619
Mouse
embryonic heart tube development GO:0035050 22 0.618
Mouse
renal filtration cell differentiation GO:0061318 12 0.612
Mouse
growth GO:0040007 359 0.602
genitalia morphogenesis GO:0035112 16 0.595
compound eye photoreceptor development GO:0042051 78 0.591
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316 1 0.589
small molecule metabolic process GO:0044281 305 0.583
branching morphogenesis of an epithelial tube GO:0048754 45 0.583
Mouse
left right axis specification GO:0070986 1 0.582
Mouse
cardiac muscle tissue development GO:0048738 9 0.579
Mouse
positive regulation of programmed cell death GO:0043068 62 0.578
Mouse
sex differentiation GO:0007548 81 0.576
developmental growth GO:0048589 280 0.575
Zebrafish Mouse Rat
cardioblast differentiation GO:0010002 20 0.573
muscle structure development GO:0061061 224 0.568
regulation of gene expression epigenetic GO:0040029 128 0.563
oocyte fate commitment GO:0048600 2 0.561
organonitrogen compound metabolic process GO:1901564 318 0.561
salivary gland morphogenesis GO:0007435 145 0.559
negative regulation of cardioblast differentiation GO:0051892 7 0.559
epithelial cell proliferation GO:0050673 15 0.555
positive regulation of gene expression GO:0010628 290 0.554
cellular response to chemical stimulus GO:0070887 199 0.553
Human Mouse
meiotic chromosome movement towards spindle pole GO:0016344 1 0.553
response to transforming growth factor beta GO:0071559 18 0.547
regulation of tube architecture open tracheal system GO:0035152 68 0.545
localization of cell GO:0051674 257 0.545
dna conformation change GO:0071103 105 0.544
regulation of neuron differentiation GO:0045664 103 0.540
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.539
neural precursor cell proliferation GO:0061351 75 0.532
Zebrafish Rat
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.531
regulation of cellular protein metabolic process GO:0032268 243 0.529
positive regulation of neurogenesis GO:0050769 41 0.527
Mouse Rat
juvenile hormone mediated signaling pathway GO:0035626 3 0.514
formation of primary germ layer GO:0001704 24 0.513
Zebrafish
gtp catabolic process GO:0006184 72 0.512
negative regulation of signaling GO:0023057 219 0.512
Mouse
sensory organ precursor cell fate determination GO:0016360 19 0.510
axonogenesis GO:0007409 290 0.506
positive regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0090282 1 0.500
maintenance of blood brain barrier GO:0035633 1 0.498
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 266 0.497
negative regulation of cell development GO:0010721 62 0.496
positive regulation of chromatin silencing at telomere GO:0031940 2 0.486
instar larval development GO:0002168 55 0.485
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.476
positive regulation of rna metabolic process GO:0051254 271 0.473
negative regulation of cell fate specification GO:0009996 15 0.471
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.458
positive regulation of macromolecule metabolic process GO:0010604 405 0.458
hindgut development GO:0061525 58 0.455
regulation of cell projection organization GO:0031344 92 0.455
body morphogenesis GO:0010171 2 0.452
Zebrafish Worm
meiotic spindle checkpoint GO:0044779 1 0.449
mesenchymal cell development GO:0014031 1 0.446
Human Mouse
striated muscle cell differentiation GO:0051146 90 0.445
Human Mouse
spermatogenesis GO:0007283 200 0.444
Rat
negative regulation of eye photoreceptor cell development GO:0042480 3 0.442
dna templated transcriptional start site selection GO:0001173 1 0.438
negative regulation of compound eye photoreceptor development GO:0045316 3 0.436
regulation of axonogenesis GO:0050770 32 0.433
p granule organization GO:0030719 4 0.431
chemosensory behavior GO:0007635 106 0.431
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.430
taxis GO:0042330 304 0.423
imaginal disc derived wing morphogenesis GO:0007476 337 0.421
cell type specific apoptotic process GO:0097285 38 0.421
developmental pigmentation GO:0048066 68 0.413
death GO:0016265 284 0.411
Human Mouse
peripheral nervous system development GO:0007422 52 0.411
posttranscriptional regulation of gene expression GO:0010608 145 0.403
specification of segmental identity antennal segment GO:0007383 2 0.399
negative regulation of rna metabolic process GO:0051253 251 0.399
Mouse
negative regulation of dna templated transcription initiation GO:2000143 1 0.398
regulation of ran gtpase activity GO:0032316 1 0.395
regulation of cell fate commitment GO:0010453 29 0.394
positive regulation of muscle organ development GO:0048636 6 0.390
Mouse
single organism cell adhesion GO:0098602 47 0.390
striated muscle cell development GO:0055002 50 0.385
Human
regulation of epithelial cell migration GO:0010632 12 0.375
Human
stem cell proliferation GO:0072089 88 0.372
Rat
regulation of heart induction GO:0090381 3 0.369
mesodermal cell fate commitment GO:0001710 7 0.368
Zebrafish
response to other organism GO:0051707 293 0.367
larval lymph gland hemopoiesis GO:0035167 17 0.367
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 1 0.362
regulation of cell development GO:0060284 215 0.360
learning GO:0007612 75 0.360
negative regulation of mrna 3 end processing GO:0031441 3 0.358
regulation of protein catabolic process GO:0042176 55 0.358
negative regulation of epithelial cell migration GO:0010633 1 0.355
Human
negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902166 1 0.354
positive regulation of gtpase activity GO:0043547 43 0.354
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.353
protein import into nucleus GO:0006606 51 0.352
positive regulation of catalytic activity GO:0043085 118 0.351
response to radiation GO:0009314 155 0.349
chromosome segregation GO:0007059 157 0.348
dna integration GO:0015074 1 0.348
epidermal cell differentiation GO:0009913 51 0.347
Mouse
epidermis development GO:0008544 65 0.346
Mouse
lateral inhibition GO:0046331 206 0.343
regulation of synapse assembly GO:0051963 94 0.340
septin ring organization GO:0031106 1 0.339
pigmentation GO:0043473 75 0.337
regulation of trichome morphogenesis GO:2000039 3 0.334
organophosphate metabolic process GO:0019637 195 0.334
wnt signaling pathway GO:0016055 98 0.332
Mouse
regulation of anatomical structure size GO:0090066 163 0.330
Zebrafish
nucleoside phosphate metabolic process GO:0006753 162 0.330
macromolecular complex assembly GO:0065003 256 0.328
tube morphogenesis GO:0035239 191 0.328
cuticle pattern formation GO:0035017 27 0.326
nurse cell nucleus anchoring GO:0007302 1 0.325
cellular response to oxygen containing compound GO:1901701 79 0.322
purine containing compound metabolic process GO:0072521 155 0.318
heart development GO:0007507 82 0.317
regulation of organ morphogenesis GO:2000027 78 0.317
regulation of proteasomal protein catabolic process GO:0061136 39 0.317
negative regulation of cellular biosynthetic process GO:0031327 277 0.315
Mouse
kidney development GO:0001822 3 0.315
Zebrafish Mouse
negative regulation of transcription from rna polymerase iii promoter GO:0016480 2 0.313
oviposition GO:0018991 19 0.310
Worm
negative regulation of sister chromatid cohesion GO:0045875 1 0.310
spinal cord dorsal ventral patterning GO:0021513 1 0.308
macromolecule catabolic process GO:0009057 161 0.308
response to hypoxia GO:0001666 53 0.307
Mouse
cellular response to organic substance GO:0071310 132 0.307
Human
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 2 0.305
asymmetric protein localization GO:0008105 33 0.305
cellular protein localization GO:0034613 160 0.300
neuroblast fate determination GO:0007400 12 0.299
regulation of cell fate specification GO:0042659 27 0.299
negative regulation of notch signaling pathway GO:0045746 41 0.299
carbohydrate derivative metabolic process GO:1901135 217 0.298
protein catabolic process GO:0030163 101 0.297
trachea development GO:0060438 29 0.296
cytoplasmic sequestering of nf kappab GO:0007253 1 0.294
malpighian tubule morphogenesis GO:0007443 44 0.294
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 1 0.291
establishment of organelle localization GO:0051656 122 0.290
muscle organ development GO:0007517 127 0.289
release of cytoplasmic sequestered nf kappab GO:0008588 1 0.285
positive regulation of protein modification process GO:0031401 58 0.284
regulation of hematopoietic stem cell differentiation GO:1902036 1 0.282
regulation of protein metabolic process GO:0051246 256 0.280
neuroblast proliferation GO:0007405 74 0.278
Rat
negative regulation of signal transduction GO:0009968 206 0.278
Mouse
meiotic dna repair synthesis GO:0000711 3 0.276
regulation of muscle organ development GO:0048634 13 0.274
Human Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.273
actin filament bundle assembly GO:0051017 26 0.271
cell morphogenesis involved in malpighian tubule morphogenesis GO:0061336 1 0.269
homeostatic process GO:0042592 199 0.269
single organismal cell cell adhesion GO:0016337 45 0.266
positive regulation of cell maturation GO:1903431 2 0.259
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.258
purine ribonucleotide catabolic process GO:0009154 109 0.258
maintenance of chromatin silencing GO:0006344 0 0.257
positive regulation of pole plasm oskar mrna localization GO:0045856 2 0.256
stress granule disassembly GO:0035617 1 0.254
regulation of phosphorus metabolic process GO:0051174 210 0.252
intracellular transport GO:0046907 228 0.251
regulation of protein phosphorylation GO:0001932 64 0.246
regulation of synaptic transmission GO:0050804 69 0.245
ribonucleotide catabolic process GO:0009261 109 0.244
neuroblast fate commitment GO:0014017 19 0.244
enzyme linked receptor protein signaling pathway GO:0007167 179 0.243
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.243
Mouse
protein transport GO:0015031 155 0.242
Mouse
establishment of protein localization GO:0045184 163 0.242
Mouse
positive regulation of cellular catabolic process GO:0031331 95 0.241
oocyte nucleus migration involved in oocyte dorsal ventral axis specification GO:0007312 4 0.241
nuclear axial expansion GO:0035191 3 0.239
response to biotic stimulus GO:0009607 294 0.239
response to red light GO:0010114 2 0.239
positive regulation of viral entry into host cell GO:0046598 2 0.239
compound eye cone cell differentiation GO:0042675 13 0.236
regulation of synapse structure and activity GO:0050803 128 0.236
protein modification by small protein conjugation or removal GO:0070647 106 0.235
ribonucleoside triphosphate catabolic process GO:0009203 108 0.235
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 2 0.232
positive regulation of synaptic vesicle exocytosis GO:2000302 1 0.229
protein phosphorylation GO:0006468 169 0.225
germarium derived cystoblast division GO:0048142 3 0.224
ribonucleoside metabolic process GO:0009119 127 0.224
regulation of viral entry into host cell GO:0046596 2 0.223
centripetally migrating follicle cell migration GO:0060269 1 0.222
border follicle cell migration GO:0007298 113 0.221
fatty acid derivative biosynthetic process GO:1901570 1 0.220
microtubule sliding GO:0051012 3 0.220
regulation of nuclear division GO:0051783 58 0.220
Worm
maintenance of sister chromatid cohesion GO:0034086 1 0.220
regulation of chromosome condensation GO:0060623 1 0.220
stomatogastric nervous system development GO:0007421 2 0.217
glycosyl compound catabolic process GO:1901658 112 0.214
organelle assembly GO:0070925 198 0.213
ganglion mother cell fate determination GO:0007402 2 0.212
negative regulation of nurse cell apoptotic process GO:0045849 2 0.210
small gtpase mediated signal transduction GO:0007264 88 0.206
Human
nucleobase containing compound catabolic process GO:0034655 165 0.206
regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0000117 1 0.205
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.204
organ growth GO:0035265 56 0.204
Mouse
compound eye retinal cell programmed cell death GO:0046667 23 0.202
nucleotide catabolic process GO:0009166 109 0.198
actin cytoskeleton organization GO:0030036 206 0.193
glial cell differentiation GO:0010001 35 0.192
positive regulation of gliogenesis GO:0014015 5 0.189
Mouse Rat
anterior posterior axis specification follicular epithelium GO:0030714 2 0.189
ribonucleoprotein complex disassembly GO:0032988 1 0.187
negative regulation of meiotic cell cycle phase transition GO:1901994 1 0.186
regulation of rap gtpase activity GO:0032317 3 0.185
somatic stem cell maintenance GO:0035019 14 0.185
Zebrafish
trichome morphogenesis GO:0010090 3 0.184

N disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.451
Human
heart valve disease DOID:4079 0 0.451
Human
disease of anatomical entity DOID:7 0 0.451
Human
cardiovascular system disease DOID:1287 0 0.451
Human
aortic valve disease DOID:62 0 0.451
Human
organ system benign neoplasm DOID:0060085 0 0.427
pilomatrixoma DOID:5374 0 0.427
hair follicle neoplasm DOID:5375 0 0.427
benign neoplasm DOID:0060072 0 0.427
disease of cellular proliferation DOID:14566 0 0.427
skin benign neoplasm DOID:3165 0 0.427
integumentary system benign neoplasm DOID:0060121 0 0.427
myopathy DOID:423 0 0.398
muscular disease DOID:0080000 0 0.398
cardiomyopathy DOID:0050700 0 0.398
intrinsic cardiomyopathy DOID:0060036 0 0.398
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.398
musculoskeletal system disease DOID:17 0 0.398
muscle tissue disease DOID:66 0 0.398
hepatobiliary disease DOID:3118 0 0.339
Human
gastrointestinal system disease DOID:77 0 0.339
Human
liver disease DOID:409 0 0.339
Human
alagille syndrome DOID:9245 0 0.339
Human
artery disease DOID:0050828 0 0.337
vascular disease DOID:178 0 0.337
aortic disease DOID:520 0 0.337
costello syndrome DOID:0050469 0 0.301
leopard syndrome DOID:14291 0 0.291
disease of metabolism DOID:0014667 0 0.291
hemochromatosis DOID:2352 0 0.291
inherited metabolic disorder DOID:655 0 0.291
metal metabolism disorder DOID:896 0 0.291
familial meningioma DOID:4586 0 0.285
nervous system cancer DOID:3093 0 0.285
central nervous system cancer DOID:3620 0 0.285
cancer DOID:162 0 0.285
organ system cancer DOID:0050686 0 0.285
meningioma DOID:3565 0 0.285
hajdu cheney syndrome DOID:2736 0 0.271
Human
aortic valve stenosis DOID:1712 0 0.258
Human
female reproductive system disease DOID:229 0 0.258
ovarian disease DOID:1100 0 0.258
reproductive system disease DOID:15 0 0.258
premature ovarian failure DOID:5426 0 0.258
nervous system benign neoplasm DOID:0060115 0 0.223
immune system cancer DOID:0060083 0 0.201
hematologic cancer DOID:2531 0 0.201
bone marrow cancer DOID:4960 0 0.201