Drosophila melanogaster

198 known processes

Invadolysin (Dmel_CG3953)

CG3953 gene product from transcript CG3953-RA

(Aliases: Dmel\CG3953,IX-14,l(3)SG34,DmIX-14,invadolysin,CG3953,l(3)IX-14)

Invadolysin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric neuroblast division GO:0055059 33 0.183
regulation of localization GO:0032879 275 0.179
chromosome organization GO:0051276 360 0.177
positive regulation of signal transduction GO:0009967 223 0.170
negative regulation of cellular metabolic process GO:0031324 382 0.169
growth GO:0040007 359 0.152
taxis GO:0042330 304 0.142
negative regulation of response to stimulus GO:0048585 258 0.141
cell motility GO:0048870 251 0.131
rhythmic process GO:0048511 106 0.127
carbohydrate derivative metabolic process GO:1901135 217 0.125
columnar cuboidal epithelial cell development GO:0002066 249 0.119
cellular macromolecule localization GO:0070727 220 0.094
germ cell migration GO:0008354 43 0.093
establishment of localization in cell GO:0051649 402 0.092
locomotory behavior GO:0007626 176 0.087
cell cell junction assembly GO:0007043 38 0.087
organic acid metabolic process GO:0006082 103 0.083
epithelial cell differentiation GO:0030855 322 0.077
pigment metabolic process GO:0042440 84 0.077
pigment biosynthetic process GO:0046148 36 0.075
small molecule metabolic process GO:0044281 305 0.073
localization of cell GO:0051674 257 0.072
defense response GO:0006952 300 0.071
positive regulation of response to stimulus GO:0048584 323 0.070
regulation of protein metabolic process GO:0051246 256 0.070
centrosome organization GO:0051297 163 0.069
response to abiotic stimulus GO:0009628 341 0.068
nuclear division GO:0000280 332 0.061
dna conformation change GO:0071103 105 0.060
gliogenesis GO:0042063 80 0.060
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.057
transcription from rna polymerase ii promoter GO:0006366 368 0.057
single organism intracellular transport GO:1902582 207 0.056
oxoacid metabolic process GO:0043436 103 0.056
eye pigment metabolic process GO:0042441 33 0.055
regulation of circadian rhythm GO:0042752 49 0.052
dendrite morphogenesis GO:0048813 199 0.052
glial cell development GO:0021782 27 0.052
sensory perception GO:0007600 196 0.052
ribonucleotide metabolic process GO:0009259 145 0.051
stem cell division GO:0017145 69 0.050
single organism behavior GO:0044708 391 0.049
establishment of glial blood brain barrier GO:0060857 14 0.048
response to temperature stimulus GO:0009266 106 0.048
cellular response to chemical stimulus GO:0070887 199 0.048
imaginal disc derived appendage development GO:0048737 399 0.048
single organism biosynthetic process GO:0044711 206 0.048
protein localization GO:0008104 284 0.047
wnt signaling pathway GO:0016055 98 0.047
cellular protein modification process GO:0006464 438 0.047
regulation of mitotic cell cycle GO:0007346 190 0.047
cellular ketone metabolic process GO:0042180 24 0.046
organelle fission GO:0048285 340 0.046
kidney epithelium development GO:0072073 3 0.045
sensory organ morphogenesis GO:0090596 260 0.045
apical junction assembly GO:0043297 32 0.044
organonitrogen compound metabolic process GO:1901564 318 0.044
nucleoside triphosphate catabolic process GO:0009143 108 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.043
segmentation GO:0035282 207 0.042
enzyme linked receptor protein signaling pathway GO:0007167 179 0.042
oocyte differentiation GO:0009994 145 0.041
neuronal stem cell division GO:0036445 35 0.041
organonitrogen compound catabolic process GO:1901565 128 0.041
positive regulation of cell communication GO:0010647 250 0.040
negative regulation of rna biosynthetic process GO:1902679 240 0.040
purine ribonucleotide metabolic process GO:0009150 145 0.040
purine ribonucleoside metabolic process GO:0046128 127 0.040
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
neuroblast division GO:0055057 35 0.040
oocyte construction GO:0007308 112 0.039
organic substance transport GO:0071702 257 0.039
eye development GO:0001654 323 0.039
pigment metabolic process involved in pigmentation GO:0043474 33 0.038
neurological system process GO:0050877 358 0.037
carboxylic acid metabolic process GO:0019752 92 0.037
cellular protein localization GO:0034613 160 0.037
asymmetric stem cell division GO:0098722 49 0.036
positive regulation of apoptotic signaling pathway GO:2001235 4 0.036
response to organic substance GO:0010033 284 0.035
stem cell proliferation GO:0072089 88 0.035
steroid biosynthetic process GO:0006694 16 0.035
positive regulation of organelle organization GO:0010638 65 0.035
epidermis development GO:0008544 65 0.034
cell death GO:0008219 279 0.034
regulation of epithelial cell proliferation GO:0050678 4 0.034
covalent chromatin modification GO:0016569 106 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.033
eye pigment biosynthetic process GO:0006726 32 0.033
regulation of pole plasm oskar mrna localization GO:0007317 27 0.033
aromatic compound catabolic process GO:0019439 166 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
regulation of protein localization GO:0032880 76 0.032
immune response activating signal transduction GO:0002757 2 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.032
purine containing compound catabolic process GO:0072523 112 0.032
sensory perception of mechanical stimulus GO:0050954 72 0.032
ovarian follicle cell development GO:0030707 248 0.032
positive regulation of signaling GO:0023056 243 0.031
epithelial cell development GO:0002064 274 0.031
circadian behavior GO:0048512 76 0.031
sister chromatid segregation GO:0000819 92 0.031
regulation of cellular amine metabolic process GO:0033238 3 0.031
gland development GO:0048732 191 0.031
chromosome segregation GO:0007059 157 0.030
negative regulation of epithelial cell proliferation GO:0050680 4 0.030
homeostatic process GO:0042592 199 0.030
positive regulation of protein metabolic process GO:0051247 128 0.030
regionalization GO:0003002 416 0.029
protein phosphorylation GO:0006468 169 0.029
regulation of behavior GO:0050795 75 0.029
immune system process GO:0002376 347 0.029
detection of stimulus GO:0051606 156 0.029
protein transport GO:0015031 155 0.029
regulation of immune system process GO:0002682 176 0.029
death GO:0016265 284 0.029
kidney development GO:0001822 3 0.028
negative regulation of gene expression GO:0010629 387 0.028
intracellular transport GO:0046907 228 0.028
chromatin organization GO:0006325 207 0.028
carbohydrate derivative catabolic process GO:1901136 118 0.027
negative regulation of cellular component organization GO:0051129 108 0.027
ion transport GO:0006811 145 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.027
ribonucleoside metabolic process GO:0009119 127 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
ribonucleoside triphosphate catabolic process GO:0009203 108 0.027
mitotic nuclear division GO:0007067 213 0.027
chromosome localization GO:0050000 20 0.026
regulation of catalytic activity GO:0050790 185 0.026
regulation of cell death GO:0010941 173 0.026
organonitrogen compound biosynthetic process GO:1901566 117 0.026
negative regulation of transcription dna templated GO:0045892 237 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
nephron tubule morphogenesis GO:0072078 3 0.026
negative regulation of cell communication GO:0010648 223 0.026
oocyte maturation GO:0001556 3 0.026
purine containing compound metabolic process GO:0072521 155 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
rhythmic behavior GO:0007622 76 0.026
heterochromatin organization GO:0070828 25 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
meiotic cell cycle GO:0051321 171 0.026
histone modification GO:0016570 106 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
regulation of transport GO:0051049 181 0.025
regulation of organelle organization GO:0033043 196 0.025
oocyte development GO:0048599 124 0.025
embryonic pattern specification GO:0009880 174 0.025
embryonic morphogenesis GO:0048598 206 0.025
negative regulation of microtubule depolymerization GO:0007026 21 0.025
nucleotide metabolic process GO:0009117 161 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.024
nucleoside catabolic process GO:0009164 112 0.024
circadian sleep wake cycle GO:0042745 28 0.024
neural precursor cell proliferation GO:0061351 75 0.024
protein modification process GO:0036211 438 0.024
central nervous system development GO:0007417 201 0.024
cognition GO:0050890 141 0.024
anterior posterior pattern specification GO:0009952 136 0.023
purine nucleoside catabolic process GO:0006152 112 0.023
camera type eye development GO:0043010 4 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
proteolysis GO:0006508 192 0.023
regulation of chromosome organization GO:0033044 64 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
appendage morphogenesis GO:0035107 397 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
detection of abiotic stimulus GO:0009582 66 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
adult behavior GO:0030534 137 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
immune response GO:0006955 246 0.022
microtubule organizing center organization GO:0031023 168 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
regulation of response to external stimulus GO:0032101 115 0.022
chromatin modification GO:0016568 147 0.021
cellular homeostasis GO:0019725 80 0.021
innate immune response GO:0045087 144 0.021
cell growth GO:0016049 108 0.021
eye morphogenesis GO:0048592 260 0.021
microtubule polymerization or depolymerization GO:0031109 39 0.021
vesicle mediated transport GO:0016192 381 0.021
dna packaging GO:0006323 91 0.021
regulation of tor signaling GO:0032006 21 0.021
epidermal cell differentiation GO:0009913 51 0.021
phosphorylation GO:0016310 294 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
establishment of protein localization GO:0045184 163 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
organophosphate metabolic process GO:0019637 195 0.021
regulation of locomotion GO:0040012 42 0.021
nephron development GO:0072006 3 0.020
cytoplasmic transport GO:0016482 130 0.020
neuron projection guidance GO:0097485 241 0.020
single organism cellular localization GO:1902580 180 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
nucleoside metabolic process GO:0009116 127 0.020
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
appendage development GO:0048736 401 0.020
response to hexose GO:0009746 3 0.020
response to radiation GO:0009314 155 0.020
negative regulation of signal transduction GO:0009968 206 0.020
circadian sleep wake cycle process GO:0022410 24 0.020
endocytosis GO:0006897 310 0.020
skin development GO:0043588 65 0.019
response to light stimulus GO:0009416 124 0.019
regulation of multi organism process GO:0043900 131 0.019
neuroblast proliferation GO:0007405 74 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
organophosphate catabolic process GO:0046434 112 0.019
gastrulation with mouth forming first GO:0001703 36 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.019
chromosome condensation GO:0030261 41 0.019
regulation of response to stress GO:0080134 200 0.019
lipid homeostasis GO:0055088 33 0.019
peptidyl threonine phosphorylation GO:0018107 2 0.019
nucleotide catabolic process GO:0009166 109 0.019
ecdysteroid metabolic process GO:0045455 19 0.019
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.019
negative regulation of cell proliferation GO:0008285 69 0.019
purine nucleoside biosynthetic process GO:0042451 3 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
developmental maturation GO:0021700 172 0.019
lipid biosynthetic process GO:0008610 46 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
insulin receptor signaling pathway GO:0008286 25 0.018
cellular response to abiotic stimulus GO:0071214 58 0.018
detection of chemical stimulus GO:0009593 93 0.018
phagocytosis GO:0006909 215 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
dna metabolic process GO:0006259 227 0.018
positive regulation of immune system process GO:0002684 68 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
kidney morphogenesis GO:0060993 3 0.018
mitotic sister chromatid segregation GO:0000070 87 0.017
developmental programmed cell death GO:0010623 138 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
positive regulation of cell death GO:0010942 69 0.017
mitotic sister chromatid separation GO:0051306 30 0.017
histolysis GO:0007559 102 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
glycosyl compound biosynthetic process GO:1901659 3 0.017
small molecule biosynthetic process GO:0044283 37 0.017
adult locomotory behavior GO:0008344 76 0.017
cation transport GO:0006812 110 0.017
regulation of immune effector process GO:0002697 52 0.016
establishment of chromosome localization GO:0051303 20 0.016
regulation of cell cycle GO:0051726 291 0.016
regulation of immune response GO:0050776 118 0.016
regulation of defense response GO:0031347 102 0.016
dephosphorylation GO:0016311 51 0.016
regulation of cell cycle process GO:0010564 181 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
organic substance catabolic process GO:1901575 308 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
gastrulation involving germ band extension GO:0010004 36 0.016
cilium assembly GO:0042384 38 0.016
positive regulation of cell cycle GO:0045787 43 0.015
ribonucleoside monophosphate metabolic process GO:0009161 51 0.015
regulation of meiosis GO:0040020 3 0.015
embryonic axis specification GO:0000578 107 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.015
apoptotic process GO:0006915 159 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
regulation of cellular response to insulin stimulus GO:1900076 17 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.015
digestive tract development GO:0048565 149 0.015
atp metabolic process GO:0046034 49 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
regulation of cellular localization GO:0060341 136 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
nephron epithelium development GO:0072009 3 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
somatic stem cell division GO:0048103 37 0.014
chemotaxis GO:0006935 249 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
developmental cell growth GO:0048588 52 0.014
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.014
salivary gland morphogenesis GO:0007435 145 0.014
regulation of protein transport GO:0051223 57 0.014
neuron recognition GO:0008038 101 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
cell junction organization GO:0034330 57 0.014
metal ion transport GO:0030001 74 0.014
dendrite development GO:0016358 204 0.014
forebrain development GO:0030900 2 0.014
axon target recognition GO:0007412 16 0.014
response to other organism GO:0051707 293 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
ovarian fusome organization GO:0030723 11 0.014
developmental growth GO:0048589 280 0.013
dorsal ventral axis specification GO:0009950 66 0.013
protein complex biogenesis GO:0070271 201 0.013
regulation of intracellular protein transport GO:0033157 46 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
ameboidal type cell migration GO:0001667 151 0.013
protein localization to organelle GO:0033365 82 0.013
ribonucleoside biosynthetic process GO:0042455 3 0.013
positive regulation of protein phosphorylation GO:0001934 34 0.013
negative regulation of cell development GO:0010721 62 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
regulation of gene silencing GO:0060968 63 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
response to oxygen containing compound GO:1901700 200 0.013
ommochrome biosynthetic process GO:0006727 19 0.013
regulation of apoptotic process GO:0042981 130 0.013
macromolecular complex disassembly GO:0032984 37 0.013
cell recognition GO:0008037 102 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
cellular response to insulin stimulus GO:0032869 28 0.013
programmed cell death GO:0012501 257 0.013
cell junction assembly GO:0034329 42 0.013
compound eye development GO:0048749 307 0.013
centriole replication GO:0007099 24 0.013
single organism catabolic process GO:0044712 228 0.013
lipid localization GO:0010876 54 0.013
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
neuronal action potential GO:0019228 10 0.013
positive regulation of multi organism process GO:0043902 40 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
regulation of heterochromatin assembly GO:0031445 8 0.013
positive regulation of immune response GO:0050778 63 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.012
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.012
embryonic organ development GO:0048568 50 0.012
response to lipopolysaccharide GO:0032496 4 0.012
detection of external stimulus GO:0009581 66 0.012
protein complex assembly GO:0006461 200 0.012
regulation of cellular response to stress GO:0080135 89 0.012
mitochondrial fission GO:0000266 8 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
connective tissue development GO:0061448 3 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
anterior posterior axis specification GO:0009948 109 0.012
septate junction assembly GO:0019991 26 0.012
regulation of cell differentiation GO:0045595 302 0.012
cellular chemical homeostasis GO:0055082 40 0.012
positive regulation of mitotic cell cycle GO:0045931 34 0.012
regulation of protein localization to nucleus GO:1900180 29 0.012
regulation of cell proliferation GO:0042127 163 0.012
regulation of catabolic process GO:0009894 170 0.012
retina development in camera type eye GO:0060041 4 0.012
negative regulation of growth GO:0045926 84 0.011
camera type eye morphogenesis GO:0048593 2 0.011
eye pigmentation GO:0048069 43 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
metaphase plate congression GO:0051310 19 0.011
intracellular protein transmembrane transport GO:0065002 4 0.011
positive regulation of dna metabolic process GO:0051054 12 0.011
cell division GO:0051301 248 0.011
response to external biotic stimulus GO:0043207 293 0.011
protein kinase b signaling GO:0043491 1 0.011
macromolecular complex assembly GO:0065003 256 0.011
response to biotic stimulus GO:0009607 294 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
negative regulation of organelle organization GO:0010639 56 0.011
peptidyl threonine modification GO:0018210 3 0.011
multicellular organismal signaling GO:0035637 12 0.011
purine ribonucleoside biosynthetic process GO:0046129 3 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
axon guidance GO:0007411 233 0.011
detection of light stimulus GO:0009583 58 0.011
regulation of growth GO:0040008 233 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
nephron tubule development GO:0072080 3 0.011
microtubule based movement GO:0007018 51 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
regulation of autophagy GO:0010506 62 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
embryonic hemopoiesis GO:0035162 26 0.011
mrna processing GO:0006397 104 0.011
response to monosaccharide GO:0034284 4 0.011
monocarboxylic acid transport GO:0015718 3 0.011
translation GO:0006412 69 0.011
response to anesthetic GO:0072347 9 0.011
glial cell differentiation GO:0010001 35 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
nephron morphogenesis GO:0072028 3 0.011
chromatin remodeling GO:0006338 72 0.011
wing disc morphogenesis GO:0007472 344 0.011
response to mechanical stimulus GO:0009612 28 0.011
canonical wnt signaling pathway GO:0060070 21 0.010
oxidation reduction process GO:0055114 123 0.010
hematopoietic or lymphoid organ development GO:0048534 57 0.010
necrotic cell death GO:0070265 1 0.010
mitotic chromosome condensation GO:0007076 22 0.010
regulation of mapk cascade GO:0043408 92 0.010
protein depolymerization GO:0051261 31 0.010
positive regulation of cellular component biogenesis GO:0044089 80 0.010
gland morphogenesis GO:0022612 145 0.010
regulation of translation GO:0006417 56 0.010
regulation of cell projection organization GO:0031344 92 0.010
autophagic cell death GO:0048102 83 0.010
negative regulation of homeostatic process GO:0032845 2 0.010
cilium organization GO:0044782 41 0.010
spindle assembly involved in meiosis GO:0090306 20 0.010
locomotor rhythm GO:0045475 56 0.010
regulation of membrane potential GO:0042391 35 0.010

Invadolysin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011