Drosophila melanogaster

89 known processes

AGO3 (Dmel_CG40300)

Argonaute 3

(Aliases: BEST:LD15785,Dmel\CG40300,CG40300,Ago3,Ago-3,dAgo3,ago3)

AGO3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of gene expression GO:0010628 290 0.350
oocyte development GO:0048599 124 0.268
regionalization GO:0003002 416 0.222
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.218
columnar cuboidal epithelial cell development GO:0002066 249 0.153
positive regulation of cellular biosynthetic process GO:0031328 316 0.149
positive regulation of rna metabolic process GO:0051254 271 0.144
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.133
regulation of embryonic pattern specification GO:1902875 27 0.132
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.120
regulation of pole plasm oskar mrna localization GO:0007317 27 0.100
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.098
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.095
positive regulation of rna biosynthetic process GO:1902680 266 0.094
chorion containing eggshell formation GO:0007304 105 0.092
pole plasm oskar mrna localization GO:0045451 46 0.090
intracellular mrna localization GO:0008298 66 0.089
single organism behavior GO:0044708 391 0.086
developmental maturation GO:0021700 172 0.086
anterior posterior axis specification GO:0009948 109 0.085
appendage development GO:0048736 401 0.084
cell division GO:0051301 248 0.080
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.079
positive regulation of biosynthetic process GO:0009891 316 0.078
epithelial cell development GO:0002064 274 0.077
negative regulation of rna biosynthetic process GO:1902679 240 0.076
camera type eye development GO:0043010 4 0.076
dorsal appendage formation GO:0046843 47 0.075
regulation of multicellular organismal development GO:2000026 414 0.075
regulation of cell development GO:0060284 215 0.073
negative regulation of response to stimulus GO:0048585 258 0.072
rna localization GO:0006403 115 0.070
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.068
oocyte construction GO:0007308 112 0.066
oocyte microtubule cytoskeleton organization GO:0016325 35 0.065
cell maturation GO:0048469 144 0.064
ovarian follicle cell development GO:0030707 248 0.063
dorsal ventral pattern formation GO:0009953 133 0.062
tube morphogenesis GO:0035239 191 0.062
oocyte differentiation GO:0009994 145 0.061
positive regulation of macromolecule metabolic process GO:0010604 405 0.059
reciprocal dna recombination GO:0035825 19 0.059
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.054
eggshell formation GO:0030703 105 0.054
double strand break repair GO:0006302 26 0.052
regulation of translation GO:0006417 56 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.051
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.051
pole plasm assembly GO:0007315 61 0.048
wing disc morphogenesis GO:0007472 344 0.048
axis specification GO:0009798 167 0.047
imaginal disc derived appendage morphogenesis GO:0035114 395 0.047
oocyte anterior posterior axis specification GO:0007314 72 0.047
positive regulation of response to stimulus GO:0048584 323 0.046
negative regulation of biosynthetic process GO:0009890 277 0.045
vesicle mediated transport GO:0016192 381 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.045
appendage morphogenesis GO:0035107 397 0.044
positive regulation of signal transduction GO:0009967 223 0.044
organonitrogen compound metabolic process GO:1901564 318 0.043
oocyte axis specification GO:0007309 108 0.043
positive regulation of transcription dna templated GO:0045893 266 0.043
enzyme linked receptor protein signaling pathway GO:0007167 179 0.042
cell migration GO:0016477 238 0.042
anterior posterior axis specification embryo GO:0008595 103 0.042
negative regulation of transcription dna templated GO:0045892 237 0.042
dorsal ventral axis specification GO:0009950 66 0.041
cellular response to chemical stimulus GO:0070887 199 0.041
tripartite regional subdivision GO:0007351 103 0.040
male gamete generation GO:0048232 201 0.040
cytoplasm organization GO:0007028 64 0.040
catabolic process GO:0009056 409 0.039
cellular response to organic substance GO:0071310 132 0.039
negative regulation of signal transduction GO:0009968 206 0.039
single organism cellular localization GO:1902580 180 0.039
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
cellular component assembly involved in morphogenesis GO:0010927 151 0.038
pole plasm rna localization GO:0007316 52 0.038
retina development in camera type eye GO:0060041 4 0.038
regulation of cell differentiation GO:0045595 302 0.038
response to abiotic stimulus GO:0009628 341 0.037
cell proliferation GO:0008283 299 0.037
regulation of cell maturation GO:1903429 27 0.037
establishment of localization in cell GO:0051649 402 0.036
negative regulation of cellular biosynthetic process GO:0031327 277 0.036
cellular macromolecule localization GO:0070727 220 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
spermatogenesis GO:0007283 200 0.035
blastoderm segmentation GO:0007350 159 0.035
negative regulation of developmental process GO:0051093 201 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.034
tissue migration GO:0090130 155 0.034
negative regulation of signaling GO:0023057 219 0.034
positive regulation of cell communication GO:0010647 250 0.034
ameboidal type cell migration GO:0001667 151 0.033
positive regulation of signaling GO:0023056 243 0.033
response to endogenous stimulus GO:0009719 119 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.033
regulation of embryonic development GO:0045995 68 0.032
tube development GO:0035295 244 0.032
post embryonic appendage morphogenesis GO:0035120 385 0.032
salivary gland development GO:0007431 162 0.032
digestive tract morphogenesis GO:0048546 127 0.032
regulation of cellular component biogenesis GO:0044087 201 0.031
actin filament based process GO:0030029 220 0.031
establishment or maintenance of cell polarity GO:0007163 167 0.031
single organism intracellular transport GO:1902582 207 0.031
protein modification process GO:0036211 438 0.031
tissue morphogenesis GO:0048729 297 0.031
segmentation GO:0035282 207 0.031
epithelial cell differentiation GO:0030855 322 0.031
regulation of multi organism process GO:0043900 131 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.031
cell death GO:0008219 279 0.030
response to oxygen containing compound GO:1901700 200 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
negative regulation of cell communication GO:0010648 223 0.030
localization of cell GO:0051674 257 0.030
response to organic substance GO:0010033 284 0.029
intracellular transport GO:0046907 228 0.029
mitotic nuclear division GO:0007067 213 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.028
regulation of localization GO:0032879 275 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
regulation of cell cycle GO:0051726 291 0.028
regulation of nervous system development GO:0051960 248 0.028
chromatin organization GO:0006325 207 0.028
dna recombination GO:0006310 32 0.027
negative regulation of nervous system development GO:0051961 92 0.027
organic acid metabolic process GO:0006082 103 0.027
anterior posterior pattern specification GO:0009952 136 0.027
reciprocal meiotic recombination GO:0007131 19 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
cellular catabolic process GO:0044248 372 0.026
exocrine system development GO:0035272 162 0.025
actin cytoskeleton organization GO:0030036 206 0.025
organic substance catabolic process GO:1901575 308 0.025
phosphorylation GO:0016310 294 0.025
tissue death GO:0016271 102 0.025
cellular amino acid metabolic process GO:0006520 61 0.024
dna repair GO:0006281 54 0.024
cellular amine metabolic process GO:0044106 12 0.024
cell motility GO:0048870 251 0.024
aromatic compound catabolic process GO:0019439 166 0.024
response to external biotic stimulus GO:0043207 293 0.024
positive regulation of nucleic acid templated transcription GO:1903508 266 0.024
developmental programmed cell death GO:0010623 138 0.023
maternal determination of anterior posterior axis embryo GO:0008358 74 0.023
cellular protein modification process GO:0006464 438 0.023
translation GO:0006412 69 0.022
epithelium migration GO:0090132 148 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
organelle localization GO:0051640 148 0.022
small molecule metabolic process GO:0044281 305 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
regulation of transport GO:0051049 181 0.022
polarity specification of anterior posterior axis GO:0009949 5 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
digestive tract development GO:0048565 149 0.021
eye development GO:0001654 323 0.021
rna processing GO:0006396 147 0.021
regulation of cell division GO:0051302 72 0.021
microtubule organizing center organization GO:0031023 168 0.021
negative regulation of transposition GO:0010529 12 0.021
organic substance transport GO:0071702 257 0.021
cellular response to oxygen containing compound GO:1901701 79 0.020
cytoplasmic transport GO:0016482 130 0.020
dendrite development GO:0016358 204 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.020
regulation of protein metabolic process GO:0051246 256 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
organophosphate metabolic process GO:0019637 195 0.020
nitrogen compound transport GO:0071705 85 0.020
germarium derived egg chamber formation GO:0007293 101 0.020
protein localization GO:0008104 284 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
regulation of catalytic activity GO:0050790 185 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.019
epithelial cell migration GO:0010631 148 0.019
programmed cell death GO:0012501 257 0.019
nuclear division GO:0000280 332 0.019
maintenance of location GO:0051235 73 0.019
response to nitrogen compound GO:1901698 90 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.019
regulation of organelle organization GO:0033043 196 0.019
chromosome condensation GO:0030261 41 0.019
dna conformation change GO:0071103 105 0.019
death GO:0016265 284 0.019
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.019
regulation of oskar mrna translation GO:0046011 8 0.019
nucleoside metabolic process GO:0009116 127 0.019
eye morphogenesis GO:0048592 260 0.019
amine metabolic process GO:0009308 12 0.019
phagocytosis GO:0006909 215 0.019
embryonic pattern specification GO:0009880 174 0.018
regulation of cellular component size GO:0032535 98 0.018
macromolecule catabolic process GO:0009057 161 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
salivary gland morphogenesis GO:0007435 145 0.018
intracellular signal transduction GO:0035556 300 0.018
mrna catabolic process GO:0006402 33 0.018
oxoacid metabolic process GO:0043436 103 0.018
regulation of molecular function GO:0065009 217 0.018
hindbrain development GO:0030902 2 0.018
eggshell chorion assembly GO:0007306 66 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
regulation of immune system process GO:0002682 176 0.017
body morphogenesis GO:0010171 2 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
pole plasm protein localization GO:0007318 10 0.017
oocyte dorsal ventral axis specification GO:0007310 34 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
central nervous system development GO:0007417 201 0.017
dna metabolic process GO:0006259 227 0.017
digestive system development GO:0055123 149 0.017
regulation of neuron differentiation GO:0045664 103 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.016
regulation of cellular localization GO:0060341 136 0.016
nucleotide metabolic process GO:0009117 161 0.016
ovarian follicle cell migration GO:0007297 121 0.016
regulation of neurogenesis GO:0050767 158 0.016
endocytosis GO:0006897 310 0.016
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.016
regulation of reproductive process GO:2000241 54 0.016
rna interference GO:0016246 27 0.016
defense response GO:0006952 300 0.016
regulation of cell proliferation GO:0042127 163 0.016
cellular ketone metabolic process GO:0042180 24 0.016
meiotic cell cycle process GO:1903046 132 0.016
single organism catabolic process GO:0044712 228 0.016
protein import GO:0017038 55 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
response to other organism GO:0051707 293 0.016
gland development GO:0048732 191 0.016
phosphatidylinositol mediated signaling GO:0048015 4 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
chromosome segregation GO:0007059 157 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
heterocycle catabolic process GO:0046700 166 0.015
histolysis GO:0007559 102 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
ion transport GO:0006811 145 0.015
apoptotic process GO:0006915 159 0.015
immune system process GO:0002376 347 0.015
homeostatic process GO:0042592 199 0.015
asymmetric protein localization GO:0008105 33 0.015
telencephalon development GO:0021537 2 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
lipid localization GO:0010876 54 0.015
positive regulation of nervous system development GO:0051962 69 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
regulation of notch signaling pathway GO:0008593 100 0.014
meiotic nuclear division GO:0007126 151 0.014
chaeta development GO:0022416 97 0.014
defense response to other organism GO:0098542 225 0.014
cholesterol transport GO:0030301 2 0.014
regulation of cell cycle process GO:0010564 181 0.014
ras protein signal transduction GO:0007265 88 0.014
germarium derived oocyte fate determination GO:0007294 26 0.014
response to organophosphorus GO:0046683 2 0.014
steroid catabolic process GO:0006706 1 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
inositol lipid mediated signaling GO:0048017 4 0.014
mrna processing GO:0006397 104 0.014
embryonic axis specification GO:0000578 107 0.014
negative regulation of gene expression GO:0010629 387 0.014
response to organic cyclic compound GO:0014070 89 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
positive regulation of cell development GO:0010720 61 0.013
gland morphogenesis GO:0022612 145 0.013
synaptic transmission GO:0007268 288 0.013
protein ubiquitination GO:0016567 70 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of anatomical structure size GO:0090066 163 0.013
actin filament organization GO:0007015 126 0.013
regulation of lipid transport GO:0032368 3 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
proteolysis GO:0006508 192 0.013
response to hypoxia GO:0001666 53 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
protein phosphorylation GO:0006468 169 0.013
purine containing compound metabolic process GO:0072521 155 0.013
protein complex assembly GO:0006461 200 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
sodium dependent phosphate transport GO:0044341 2 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
neurological system process GO:0050877 358 0.013
cell fate determination GO:0001709 91 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
salivary gland histolysis GO:0035070 88 0.013
response to biotic stimulus GO:0009607 294 0.013
protein complex biogenesis GO:0070271 201 0.012
r7 cell differentiation GO:0045466 43 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
photoreceptor cell development GO:0042461 96 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
response to decreased oxygen levels GO:0036293 58 0.012
regulation of oocyte development GO:0060281 27 0.012
response to bacterium GO:0009617 198 0.012
gene silencing by rna GO:0031047 57 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
response to organonitrogen compound GO:0010243 75 0.012
meiosis i GO:0007127 59 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
germarium derived oocyte differentiation GO:0030706 29 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
rhythmic behavior GO:0007622 76 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
multicellular organismal aging GO:0010259 140 0.012
regulation of response to stress GO:0080134 200 0.012
compound eye morphogenesis GO:0001745 249 0.012
regulation of catabolic process GO:0009894 170 0.012
memory GO:0007613 94 0.012
oocyte fate determination GO:0030716 27 0.012
pole plasm mrna localization GO:0019094 49 0.012
cellular response to radiation GO:0071478 52 0.012
single organism biosynthetic process GO:0044711 206 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
stem cell differentiation GO:0048863 117 0.012
border follicle cell migration GO:0007298 113 0.012
purine containing compound catabolic process GO:0072523 112 0.011
mrna metabolic process GO:0016071 124 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
carbohydrate metabolic process GO:0005975 82 0.011
developmental pigmentation GO:0048066 68 0.011
regulation of mapk cascade GO:0043408 92 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
erbb signaling pathway GO:0038127 58 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
muscle structure development GO:0061061 224 0.011
mesenchymal cell development GO:0014031 1 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
dna catabolic process GO:0006308 16 0.011
macromolecular complex assembly GO:0065003 256 0.011
mitotic cytokinesis GO:0000281 50 0.011
chromosome separation GO:0051304 42 0.011
chromosome organization GO:0051276 360 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
regulation of meiosis GO:0040020 3 0.011
peptidyl threonine modification GO:0018210 3 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
axonogenesis GO:0007409 290 0.010
wing disc pattern formation GO:0035222 66 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
dna packaging GO:0006323 91 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
positive regulation of mrna catabolic process GO:0061014 5 0.010
negative regulation of cell division GO:0051782 17 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
cellular response to ethanol GO:0071361 4 0.010
organophosphate biosynthetic process GO:0090407 46 0.010
axon guidance GO:0007411 233 0.010
organelle fission GO:0048285 340 0.010
response to oxygen levels GO:0070482 59 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
forebrain development GO:0030900 2 0.010

AGO3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.027
musculoskeletal system disease DOID:17 0 0.017
inherited metabolic disorder DOID:655 0 0.017
connective tissue disease DOID:65 0 0.012