Drosophila melanogaster

219 known processes

Abl (Dmel_CG4032)

Abl tyrosine kinase

(Aliases: dAbl,DROTKABL3,Abl1,CG4032,Dsrc7,AblK,Ableson,cAbl,DAbl,4674,abl,l(3)73Ba,D-abl,c-abl,Dabl,l(3)04674,ABL,l(3)c-abl,Ddash/abl,Dmel\CG4032,C-abl,Dash,D-ash,Am ABL,abl1)

Abl biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
axon development GO:0061564 297 0.999
axonogenesis GO:0007409 290 0.999
neuron projection guidance GO:0097485 241 0.998
taxis GO:0042330 304 0.993
axon guidance GO:0007411 233 0.989
motor neuron axon guidance GO:0008045 58 0.979
regulation of nervous system development GO:0051960 248 0.956
regulation of dendrite morphogenesis GO:0048814 28 0.951
developmental growth GO:0048589 280 0.913
regulation of cell development GO:0060284 215 0.878
Human Mouse Rat
regulation of cell projection organization GO:0031344 92 0.856
Human Mouse Rat
negative regulation of gene expression GO:0010629 387 0.854
regulation of cell differentiation GO:0045595 302 0.853
Human Mouse Rat
regulation of localization GO:0032879 275 0.825
neuromuscular junction development GO:0007528 149 0.816
positive regulation of cell migration GO:0030335 2 0.811
cell migration GO:0016477 238 0.798
dorsal ventral axon guidance GO:0033563 2 0.793
growth GO:0040007 359 0.787
regulation of multicellular organismal development GO:2000026 414 0.783
regulation of neuron differentiation GO:0045664 103 0.780
Human Mouse Rat
synaptic transmission GO:0007268 288 0.766
synapse assembly GO:0007416 143 0.761
regulation of cell morphogenesis GO:0022604 163 0.731
negative regulation of cell communication GO:0010648 223 0.730
Mouse Worm
regulation of axon extension involved in axon guidance GO:0048841 4 0.725
membrane organization GO:0061024 112 0.723
Worm
chemotaxis GO:0006935 249 0.719
positive regulation of cell motility GO:2000147 3 0.698
eye development GO:0001654 323 0.682
regulation of dendrite development GO:0050773 37 0.668
Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.647
Human
regulation of protein metabolic process GO:0051246 256 0.618
Human
regulation of cellular protein metabolic process GO:0032268 243 0.612
Human
dendrite morphogenesis GO:0048813 199 0.607
Mouse
sensory organ morphogenesis GO:0090596 260 0.594
regulation of cell proliferation GO:0042127 163 0.584
Mouse Rat
regulation of cell adhesion GO:0030155 27 0.580
Mouse
actomyosin structure organization GO:0031032 56 0.572
substrate dependent cell migration GO:0006929 3 0.566
Mouse
cell recognition GO:0008037 102 0.550
negative regulation of cellular metabolic process GO:0031324 382 0.545
Human Mouse
compound eye morphogenesis GO:0001745 249 0.540
actin filament based process GO:0030029 220 0.534
Mouse Rat
regulation of synapse assembly GO:0051963 94 0.523
morphogenesis of embryonic epithelium GO:0016331 94 0.512
regulation of cellular component biogenesis GO:0044087 201 0.507
regulation of molecular function GO:0065009 217 0.503
Human Mouse
macromolecular complex assembly GO:0065003 256 0.503
Rat
cellular protein modification process GO:0006464 438 0.502
dorsal closure GO:0007391 79 0.488
negative regulation of response to stimulus GO:0048585 258 0.474
Mouse Worm
endocytosis GO:0006897 310 0.463
Mouse Worm
multi organism reproductive behavior GO:0044705 121 0.454
positive regulation of signaling GO:0023056 243 0.451
Mouse
ovarian follicle cell development GO:0030707 248 0.450
axon extension involved in axon guidance GO:0048846 10 0.446
regulation of axonogenesis GO:0050770 32 0.444
regulation of cell migration GO:0030334 22 0.443
Worm
axon extension GO:0048675 32 0.440
positive regulation of cellular component organization GO:0051130 156 0.424
Human Mouse Rat
positive regulation of nervous system development GO:0051962 69 0.416
Human Mouse Rat
dendrite development GO:0016358 204 0.411
Mouse Rat
positive regulation of cell adhesion GO:0045785 10 0.410
negative regulation of growth GO:0045926 84 0.404
cortical actin cytoskeleton organization GO:0030866 24 0.403
regulation of growth GO:0040008 233 0.403
synapse organization GO:0050808 196 0.400
embryo development ending in birth or egg hatching GO:0009792 152 0.399
cell adhesion GO:0007155 136 0.399
Mouse
locomotory behavior GO:0007626 176 0.392
protein localization GO:0008104 284 0.388
regulation of cell death GO:0010941 173 0.387
Human Mouse Rat Worm
vesicle mediated transport GO:0016192 381 0.386
Mouse Worm
regulation of cell shape GO:0008360 113 0.383
axon choice point recognition GO:0016198 26 0.381
regulation of catalytic activity GO:0050790 185 0.372
Human
regulation of developmental growth GO:0048638 174 0.372
imaginal disc derived appendage morphogenesis GO:0035114 395 0.363
cytokinesis GO:0000910 90 0.354
regulation of protein modification process GO:0031399 112 0.353
Human
regulation of phosphorus metabolic process GO:0051174 210 0.351
Human Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.349
cortical cytoskeleton organization GO:0030865 29 0.345
cell division GO:0051301 248 0.345
positive regulation of cell projection organization GO:0031346 29 0.344
Human Mouse Rat
cell proliferation GO:0008283 299 0.333
Mouse Rat
regulation of protein polymerization GO:0032271 28 0.331
regulation of response to stress GO:0080134 200 0.330
Human Mouse Rat Worm
maintenance of protein location in cell GO:0032507 26 0.329
cell growth GO:0016049 108 0.328
Mouse
positive regulation of cellular component biogenesis GO:0044089 80 0.328
developmental maturation GO:0021700 172 0.318
Mouse
regulation of neuron projection development GO:0010975 69 0.310
Human Mouse Rat
cytoskeleton dependent cytokinesis GO:0061640 81 0.305
regulation of cellular component movement GO:0051270 42 0.303
Worm
regulation of phosphorylation GO:0042325 147 0.287
Human Mouse
renal filtration GO:0097205 7 0.283
germarium derived egg chamber formation GO:0007293 101 0.277
positive regulation of response to stimulus GO:0048584 323 0.275
Mouse Rat
immune system process GO:0002376 347 0.273
Mouse
protein modification process GO:0036211 438 0.272
negative regulation of cellular component organization GO:0051129 108 0.270
regulation of cell motility GO:2000145 23 0.269
Worm
cell projection assembly GO:0030031 94 0.265
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.262
Mouse Worm
chorion containing eggshell formation GO:0007304 105 0.260
single organism cellular localization GO:1902580 180 0.260
regulation of cytoskeleton organization GO:0051493 89 0.258
Mouse
negative regulation of catalytic activity GO:0043086 42 0.257
Human
axon midline choice point recognition GO:0016199 26 0.253
enzyme linked receptor protein signaling pathway GO:0007167 179 0.252
Mouse
eye morphogenesis GO:0048592 260 0.252
neuron recognition GO:0008038 101 0.251
positive regulation of signal transduction GO:0009967 223 0.248
Mouse
intracellular signal transduction GO:0035556 300 0.247
Human Mouse Worm
nucleus localization GO:0051647 34 0.243
positive regulation of neurogenesis GO:0050769 41 0.238
Human Mouse Rat
negative regulation of signaling GO:0023057 219 0.238
Mouse Worm
regulation of axon guidance GO:1902667 10 0.238
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.234
negative regulation of cell cycle GO:0045786 116 0.232
Mouse
mitotic cytokinesis GO:0000281 50 0.227
localization of cell GO:0051674 257 0.226
cellular macromolecule localization GO:0070727 220 0.226
negative regulation of cellular protein metabolic process GO:0032269 85 0.226
Human
positive regulation of cytoskeleton organization GO:0051495 21 0.224
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.222
actin cytoskeleton organization GO:0030036 206 0.217
Mouse Rat
actin filament bundle organization GO:0061572 28 0.216
Mouse
oocyte development GO:0048599 124 0.215
morphogenesis of an epithelium GO:0002009 276 0.214
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.214
response to endogenous stimulus GO:0009719 119 0.212
Rat
neuron projection extension GO:1990138 32 0.208
oocyte differentiation GO:0009994 145 0.208
oocyte microtubule cytoskeleton organization GO:0016325 35 0.203
lamellipodium organization GO:0097581 21 0.203
establishment of localization in cell GO:0051649 402 0.198
positive regulation of cell communication GO:0010647 250 0.198
Mouse
kidney development GO:0001822 3 0.195
maintenance of location GO:0051235 73 0.192
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.192
positive regulation of axonogenesis GO:0050772 2 0.192
purine ribonucleotide catabolic process GO:0009154 109 0.190
regulation of synaptic transmission GO:0050804 69 0.190
protein phosphorylation GO:0006468 169 0.187
neuroblast differentiation GO:0014016 29 0.183
initiation of dorsal closure GO:0007392 12 0.183
negative regulation of cellular biosynthetic process GO:0031327 277 0.180
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.179
cell death GO:0008219 279 0.179
Human Mouse Rat Worm
programmed cell death GO:0012501 257 0.178
Human Mouse Rat Worm
positive regulation of cell development GO:0010720 61 0.176
Human Mouse Rat
cellular response to chemical stimulus GO:0070887 199 0.176
Human Mouse Rat
small molecule metabolic process GO:0044281 305 0.172
regulation of actin filament based process GO:0032970 42 0.169
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.169
regulation of anatomical structure morphogenesis GO:0022603 242 0.168
embryonic development via the syncytial blastoderm GO:0001700 148 0.168
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.168
positive regulation of axon extension GO:0045773 2 0.166
single organism membrane organization GO:0044802 93 0.165
regulation of cellular ketone metabolic process GO:0010565 3 0.164
endodermal cell differentiation GO:0035987 3 0.163
developmental growth involved in morphogenesis GO:0060560 65 0.163
regulation of cellular localization GO:0060341 136 0.162
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.161
central nervous system development GO:0007417 201 0.159
purine containing compound metabolic process GO:0072521 155 0.157
spindle organization GO:0007051 253 0.156
positive regulation of programmed cell death GO:0043068 62 0.154
Human Mouse Rat
protein acetylation GO:0006473 39 0.152
morphogenesis of a branching epithelium GO:0061138 45 0.151
regulation of synapse structure and activity GO:0050803 128 0.151
appendage development GO:0048736 401 0.149
regulation of cell substrate adhesion GO:0010810 2 0.149
regulation of organelle organization GO:0033043 196 0.148
Mouse
developmental cell growth GO:0048588 52 0.145
Mouse
spermatogenesis GO:0007283 200 0.143
Worm
epidermis development GO:0008544 65 0.143
peptidyl amino acid modification GO:0018193 105 0.142
larval development GO:0002164 104 0.141
response to organic substance GO:0010033 284 0.140
Human Mouse Rat
regulation of lamellipodium organization GO:1902743 15 0.137
mitotic nuclear division GO:0007067 213 0.136
endodermal cell fate commitment GO:0001711 3 0.135
gonad morphogenesis GO:0035262 7 0.135
skin development GO:0043588 65 0.134
actin filament organization GO:0007015 126 0.134
Mouse Rat
negative regulation of biosynthetic process GO:0009890 277 0.134
regulation of neurogenesis GO:0050767 158 0.134
Human Mouse Rat
kidney epithelium development GO:0072073 3 0.132
sensory perception GO:0007600 196 0.132
neuroblast fate commitment GO:0014017 19 0.131
compound eye development GO:0048749 307 0.129
regulation of cell cycle GO:0051726 291 0.129
Mouse
regulation of response to external stimulus GO:0032101 115 0.129
hair cell differentiation GO:0035315 47 0.128
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.127
positive regulation of cellular biosynthetic process GO:0031328 316 0.127
imaginal disc derived appendage development GO:0048737 399 0.126
establishment or maintenance of cell polarity GO:0007163 167 0.126
maintenance of location in cell GO:0051651 28 0.126
single organism behavior GO:0044708 391 0.125
Mouse Rat
regulation of cellular amine metabolic process GO:0033238 3 0.124
regulation of cellular response to stress GO:0080135 89 0.122
Human Mouse Rat Worm
positive regulation of cell differentiation GO:0045597 64 0.122
Human Mouse Rat
hemocyte migration GO:0035099 19 0.121
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.121
body morphogenesis GO:0010171 2 0.120
death GO:0016265 284 0.119
Human Mouse Rat Worm
cellular protein localization GO:0034613 160 0.118
regulation of lamellipodium assembly GO:0010591 15 0.118
oocyte axis specification GO:0007309 108 0.118
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.118
Mouse
small gtpase mediated signal transduction GO:0007264 88 0.116
Mouse
secretion by cell GO:0032940 101 0.115
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.115
filopodium assembly GO:0046847 33 0.114
positive regulation of axon guidance GO:1902669 1 0.114
regulation of synapse organization GO:0050807 110 0.113
compound eye retinal cell programmed cell death GO:0046667 23 0.113
positive regulation of developmental process GO:0051094 143 0.113
Human Mouse Rat
positive regulation of protein metabolic process GO:0051247 128 0.112
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.111
positive regulation of transcription dna templated GO:0045893 266 0.110
glial cell migration GO:0008347 31 0.110
axis specification GO:0009798 167 0.109
jnk cascade GO:0007254 50 0.109
nucleobase containing small molecule metabolic process GO:0055086 174 0.108
regulation of protein transport GO:0051223 57 0.108
mapk cascade GO:0000165 107 0.108
Mouse
regulation of transferase activity GO:0051338 58 0.108
Human
regulation of mapk cascade GO:0043408 92 0.108
Mouse
negative regulation of developmental process GO:0051093 201 0.107
protein complex assembly GO:0006461 200 0.107
Rat
regulation of apoptotic process GO:0042981 130 0.107
Human Mouse Rat Worm
blastoderm segmentation GO:0007350 159 0.107
embryonic organ development GO:0048568 50 0.106
purine nucleotide metabolic process GO:0006163 146 0.105
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.104
gonad development GO:0008406 50 0.104
reproductive system development GO:0061458 74 0.104
male gamete generation GO:0048232 201 0.103
Worm
maintenance of protein location GO:0045185 28 0.101
forebrain development GO:0030900 2 0.101
positive regulation of rna metabolic process GO:0051254 271 0.101
negative regulation of rna biosynthetic process GO:1902679 240 0.100
synaptic growth at neuromuscular junction GO:0051124 119 0.099
establishment of nucleus localization GO:0040023 26 0.099
positive regulation of filopodium assembly GO:0051491 15 0.099
stress activated protein kinase signaling cascade GO:0031098 55 0.098
neurotransmitter secretion GO:0007269 35 0.098
regulation of cell cycle process GO:0010564 181 0.097
embryonic morphogenesis GO:0048598 206 0.096
regulation of notch signaling pathway GO:0008593 100 0.096
rhythmic process GO:0048511 106 0.095
cellular response to endogenous stimulus GO:0071495 80 0.095
Rat
oocyte construction GO:0007308 112 0.094
positive regulation of gene expression GO:0010628 290 0.093
gastrulation GO:0007369 70 0.093
protein catabolic process GO:0030163 101 0.093
biological adhesion GO:0022610 138 0.093
Mouse
cuticle development GO:0042335 86 0.092
microtubule anchoring GO:0034453 11 0.092
regulation of protein serine threonine kinase activity GO:0071900 25 0.092
Human
retinal ganglion cell axon guidance GO:0031290 12 0.092
epithelial cell differentiation GO:0030855 322 0.091
regulation of cell cell adhesion GO:0022407 21 0.091
Mouse
axonal defasciculation GO:0007414 12 0.091
negative regulation of phosphorylation GO:0042326 35 0.091
Human Mouse
phagocytosis GO:0006909 215 0.091
Mouse Worm
intracellular transport GO:0046907 228 0.091
peptidyl lysine acetylation GO:0018394 39 0.091
positive regulation of catalytic activity GO:0043085 118 0.088
Human
nuclear division GO:0000280 332 0.087
phenol containing compound metabolic process GO:0018958 57 0.086
g protein coupled receptor signaling pathway GO:0007186 136 0.086
intracellular protein transport GO:0006886 104 0.085
gliogenesis GO:0042063 80 0.085
Mouse
regulation of epithelial cell migration GO:0010632 12 0.085
organelle fission GO:0048285 340 0.085
establishment of organelle localization GO:0051656 122 0.085
signal release GO:0023061 49 0.085
multi organism behavior GO:0051705 175 0.084
negative regulation of signal transduction GO:0009968 206 0.083
Mouse Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.083
anterior posterior pattern specification GO:0009952 136 0.082
regulation of locomotion GO:0040012 42 0.081
Worm
digestive system development GO:0055123 149 0.081
regulation of transport GO:0051049 181 0.081
proteolysis GO:0006508 192 0.080
gtp catabolic process GO:0006184 72 0.079
regulation of protein kinase activity GO:0045859 51 0.079
Human
lamellipodium assembly GO:0030032 21 0.079
cellular amino acid metabolic process GO:0006520 61 0.078
cellular response to growth factor stimulus GO:0071363 30 0.078
Rat
organic substance transport GO:0071702 257 0.078
dorsal appendage formation GO:0046843 47 0.078
ribonucleotide catabolic process GO:0009261 109 0.078
signal transduction by phosphorylation GO:0023014 107 0.078
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.077
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.074
response to wounding GO:0009611 94 0.074
ribose phosphate metabolic process GO:0019693 145 0.073
phosphorylation GO:0016310 294 0.073
lateral inhibition GO:0046331 206 0.073
camera type eye development GO:0043010 4 0.073
regulation of cell growth GO:0001558 43 0.073
negative regulation of phosphate metabolic process GO:0045936 45 0.073
Human Mouse
single organism cell adhesion GO:0098602 47 0.072
Mouse
regulation of cell projection assembly GO:0060491 30 0.072
positive regulation of protein modification process GO:0031401 58 0.071
Human
columnar cuboidal epithelial cell development GO:0002066 249 0.071
negative regulation of erbb signaling pathway GO:1901185 29 0.071
brain development GO:0007420 120 0.071
Mouse
regulation of wnt signaling pathway GO:0030111 68 0.071
Mouse
regulation of establishment of protein localization GO:0070201 61 0.071
tissue morphogenesis GO:0048729 297 0.070
organophosphate metabolic process GO:0019637 195 0.070
neurotransmitter transport GO:0006836 37 0.070
negative regulation of developmental growth GO:0048640 64 0.069
positive regulation of locomotion GO:0040017 8 0.069
endoderm formation GO:0001706 3 0.069
negative regulation of rna metabolic process GO:0051253 251 0.069
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.069
post embryonic appendage morphogenesis GO:0035120 385 0.069
positive regulation of molecular function GO:0044093 136 0.069
Human Mouse
eye photoreceptor cell development GO:0042462 81 0.069
regulation of kinase activity GO:0043549 53 0.068
Human
cellular homeostasis GO:0019725 80 0.068
Human Mouse
actin filament bundle assembly GO:0051017 26 0.068
Mouse
nucleotide metabolic process GO:0009117 161 0.068
regulation of axon extension GO:0030516 8 0.068
telencephalon development GO:0021537 2 0.068
cell fate determination GO:0001709 91 0.068
regulation of proteolysis GO:0030162 87 0.067
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.067
reproductive behavior GO:0019098 122 0.067
single organismal cell cell adhesion GO:0016337 45 0.067
Mouse
cellular ketone metabolic process GO:0042180 24 0.067
protein transport GO:0015031 155 0.067
organelle localization GO:0051640 148 0.066
negative regulation of nucleic acid templated transcription GO:1903507 240 0.066
regulation of cellular protein catabolic process GO:1903362 44 0.065
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.065
positive regulation of cell proliferation GO:0008284 47 0.065
Mouse Rat
positive regulation of rna biosynthetic process GO:1902680 266 0.065
cellular protein complex assembly GO:0043623 71 0.065
Rat
stem cell development GO:0048864 79 0.064
nuclear migration GO:0007097 20 0.064
eggshell formation GO:0030703 105 0.064
positive regulation of jun kinase activity GO:0043507 4 0.063
macromolecule catabolic process GO:0009057 161 0.063
positive regulation of phosphorus metabolic process GO:0010562 139 0.063
Human Mouse
negative regulation of epithelial cell proliferation GO:0050680 4 0.063
positive regulation of neuron differentiation GO:0045666 26 0.062
Human Mouse Rat
positive regulation of lipid metabolic process GO:0045834 4 0.062
negative regulation of cell cycle process GO:0010948 109 0.062
cytoplasmic transport GO:0016482 130 0.061
compound eye photoreceptor cell differentiation GO:0001751 140 0.060
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
internal protein amino acid acetylation GO:0006475 38 0.060
negative regulation of cytoskeleton organization GO:0051494 30 0.059
transcription from rna polymerase ii promoter GO:0006366 368 0.059
negative regulation of protein modification process GO:0031400 29 0.059
Human
organonitrogen compound metabolic process GO:1901564 318 0.059
hemopoiesis GO:0030097 46 0.058
Mouse
cell motility GO:0048870 251 0.058
head development GO:0060322 135 0.058
Mouse
regionalization GO:0003002 416 0.057
spinal cord development GO:0021510 1 0.056
secretion GO:0046903 109 0.056
Mouse
protein complex biogenesis GO:0070271 201 0.056
Rat
regulation of microtubule based process GO:0032886 49 0.056
positive regulation of cellular protein metabolic process GO:0032270 118 0.056
Human
negative regulation of proteolysis GO:0045861 31 0.055
stress activated mapk cascade GO:0051403 52 0.055
anterior posterior axis specification GO:0009948 109 0.055
cell cycle arrest GO:0007050 4 0.055
peptidyl lysine modification GO:0018205 57 0.055
axon regeneration GO:0031103 8 0.055
mitotic cell cycle phase transition GO:0044772 138 0.054
oocyte anterior posterior axis specification GO:0007314 72 0.054
open tracheal system development GO:0007424 204 0.053
cellular catabolic process GO:0044248 372 0.052
cellular macromolecular complex assembly GO:0034622 153 0.051
Rat
mitotic spindle organization GO:0007052 220 0.051
positive regulation of transport GO:0051050 92 0.051
leg disc morphogenesis GO:0007478 80 0.051
protein polymerization GO:0051258 42 0.051
Rat
amine metabolic process GO:0009308 12 0.050
collateral sprouting GO:0048668 3 0.050
Mouse
epidermal cell differentiation GO:0009913 51 0.050
smoothened signaling pathway GO:0007224 49 0.050
nucleoside phosphate metabolic process GO:0006753 162 0.049
purine nucleoside triphosphate metabolic process GO:0009144 119 0.049
epithelial cell development GO:0002064 274 0.049
dorsal closure elongation of leading edge cells GO:0007394 10 0.049
purine nucleoside catabolic process GO:0006152 112 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.048
negative regulation of phosphorus metabolic process GO:0010563 45 0.048
Human Mouse
catabolic process GO:0009056 409 0.048
positive regulation of phosphate metabolic process GO:0045937 139 0.048
Human Mouse
homeostatic process GO:0042592 199 0.048
Human Mouse
positive regulation of cell growth GO:0030307 19 0.047
negative regulation of neurogenesis GO:0050768 53 0.047
internal peptidyl lysine acetylation GO:0018393 38 0.047
protein maturation GO:0051604 71 0.047
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.047
nucleoside catabolic process GO:0009164 112 0.046
leg disc development GO:0035218 92 0.046
regulation of hydrolase activity GO:0051336 97 0.046
Human
regulation of protein localization GO:0032880 76 0.046
single organism catabolic process GO:0044712 228 0.046
oocyte dorsal ventral axis specification GO:0007310 34 0.046
aging GO:0007568 143 0.046
Mouse
dorsal ventral axis specification GO:0009950 66 0.045
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.045
tube development GO:0035295 244 0.045
ribonucleoside metabolic process GO:0009119 127 0.045
regulation of cell size GO:0008361 63 0.044
myoblast proliferation GO:0051450 3 0.044
negative regulation of cell development GO:0010721 62 0.044
regulation of jnk cascade GO:0046328 40 0.043
regulation of embryonic development GO:0045995 68 0.043
immune response regulating signaling pathway GO:0002764 2 0.043
Mouse
single organism intracellular transport GO:1902582 207 0.043
regulation of epithelial cell proliferation GO:0050678 4 0.043
protein processing GO:0016485 68 0.042
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.042
regulation of retinal cell programmed cell death GO:0046668 18 0.042
regulation of chemotaxis GO:0050920 12 0.042
wound healing GO:0042060 75 0.042
nucleotide catabolic process GO:0009166 109 0.042
wing disc morphogenesis GO:0007472 344 0.041
regulation of nucleotide metabolic process GO:0006140 62 0.041
regulation of cellular component size GO:0032535 98 0.041
ribonucleoside triphosphate catabolic process GO:0009203 108 0.041
ribonucleoside triphosphate metabolic process GO:0009199 119 0.041
positive regulation of proteolysis GO:0045862 52 0.040
extrinsic apoptotic signaling pathway GO:0097191 1 0.040
response to external biotic stimulus GO:0043207 293 0.040
Mouse Worm
nucleoside metabolic process GO:0009116 127 0.040
mesoderm development GO:0007498 78 0.040
regulation of response to wounding GO:1903034 19 0.040
positive regulation of protein complex assembly GO:0031334 22 0.040
anatomical structure homeostasis GO:0060249 97 0.039
vesicle localization GO:0051648 55 0.039
positive regulation of biosynthetic process GO:0009891 316 0.039
pole plasm oskar mrna localization GO:0045451 46 0.039
hematopoietic or lymphoid organ development GO:0048534 57 0.039
Mouse
negative regulation of cell differentiation GO:0045596 143 0.039
regulation of microtubule cytoskeleton organization GO:0070507 41 0.039
determination of adult lifespan GO:0008340 137 0.038
compound eye photoreceptor development GO:0042051 78 0.038
positive regulation of synapse assembly GO:0051965 29 0.038
glycosyl compound catabolic process GO:1901658 112 0.038
circadian behavior GO:0048512 76 0.038
regulation of filopodium assembly GO:0051489 24 0.038
positive regulation of catabolic process GO:0009896 105 0.037
positive regulation of cellular amine metabolic process GO:0033240 0 0.037
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.037
cellular response to dna damage stimulus GO:0006974 223 0.037
Human Worm
axon target recognition GO:0007412 16 0.037
cellularization GO:0007349 90 0.037
ras protein signal transduction GO:0007265 88 0.037
Mouse
hindbrain development GO:0030902 2 0.037
Mouse
regulation of behavior GO:0050795 75 0.037
regulation of phosphatase activity GO:0010921 3 0.037
regulation of pole plasm oskar mrna localization GO:0007317 27 0.036
negative regulation of transcription dna templated GO:0045892 237 0.036
organic hydroxy compound metabolic process GO:1901615 83 0.036
purine containing compound catabolic process GO:0072523 112 0.036
adult behavior GO:0030534 137 0.036
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.036
negative regulation of cell migration GO:0030336 5 0.036
Worm
response to metal ion GO:0010038 23 0.036
pole plasm mrna localization GO:0019094 49 0.036
stem cell proliferation GO:0072089 88 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.035
negative regulation of protein metabolic process GO:0051248 85 0.035
Human
positive regulation of nucleotide metabolic process GO:0045981 55 0.035
organic cyclic compound catabolic process GO:1901361 168 0.035
spermatid differentiation GO:0048515 114 0.035
regulation of gtp catabolic process GO:0033124 44 0.035
nucleoside triphosphate metabolic process GO:0009141 120 0.035
negative regulation of synapse assembly GO:0051964 39 0.035
negative regulation of epithelial cell migration GO:0010633 1 0.034
regulation of mitotic cell cycle GO:0007346 190 0.034
Mouse
regulation of protein processing GO:0070613 32 0.034

Abl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.250
disease of cellular proliferation DOID:14566 0 0.250
organ system cancer DOID:0050686 0 0.250
disease of anatomical entity DOID:7 0 0.189