Drosophila melanogaster

0 known processes

pug (Dmel_CG4067)

pugilist

(Aliases: bs14h02.y1,CG4067,Pug,Dmel\CG4067,pugD,MTHFD)

pug biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 103 0.191
Human Yeast
catabolic process GO:0009056 409 0.096
proteolysis GO:0006508 192 0.081
carboxylic acid metabolic process GO:0019752 92 0.080
Human Yeast
organonitrogen compound biosynthetic process GO:1901566 117 0.078
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.077
negative regulation of cellular metabolic process GO:0031324 382 0.076
small molecule metabolic process GO:0044281 305 0.074
Human Yeast Rat
branched chain amino acid transport GO:0015803 3 0.074
intracellular signal transduction GO:0035556 300 0.072
organonitrogen compound metabolic process GO:1901564 318 0.071
Human Yeast
carbohydrate derivative metabolic process GO:1901135 217 0.071
alpha amino acid metabolic process GO:1901605 20 0.065
Human Yeast
organic acid metabolic process GO:0006082 103 0.062
Human Yeast
appendage development GO:0048736 401 0.059
cellular catabolic process GO:0044248 372 0.059
ion transport GO:0006811 145 0.058
nucleobase containing small molecule metabolic process GO:0055086 174 0.056
Yeast Rat
cell death GO:0008219 279 0.054
eye development GO:0001654 323 0.051
protein modification process GO:0036211 438 0.049
macromolecular complex assembly GO:0065003 256 0.047
purine containing compound metabolic process GO:0072521 155 0.045
Yeast
regulation of cellular ketone metabolic process GO:0010565 3 0.045
programmed cell death GO:0012501 257 0.044
compound eye morphogenesis GO:0001745 249 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.042
imaginal disc derived appendage development GO:0048737 399 0.042
phosphorylation GO:0016310 294 0.042
cellular protein modification process GO:0006464 438 0.040
glycosyl compound metabolic process GO:1901657 127 0.039
post embryonic appendage morphogenesis GO:0035120 385 0.039
appendage morphogenesis GO:0035107 397 0.039
head development GO:0060322 135 0.038
negative regulation of cellular biosynthetic process GO:0031327 277 0.038
pteridine containing compound metabolic process GO:0042558 6 0.037
Human Yeast
sperm individualization GO:0007291 48 0.037
regulation of protein metabolic process GO:0051246 256 0.036
response to abiotic stimulus GO:0009628 341 0.036
organic substance transport GO:0071702 257 0.036
purine ribonucleoside metabolic process GO:0046128 127 0.035
regulation of cell cycle GO:0051726 291 0.034
regulation of apoptotic process GO:0042981 130 0.034
single organism behavior GO:0044708 391 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
adult behavior GO:0030534 137 0.031
multi organism behavior GO:0051705 175 0.031
positive regulation of proteolysis GO:0045862 52 0.030
sensory organ morphogenesis GO:0090596 260 0.030
organic substance catabolic process GO:1901575 308 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
forebrain development GO:0030900 2 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.029
telencephalon development GO:0021537 2 0.029
wing disc morphogenesis GO:0007472 344 0.029
positive regulation of endopeptidase activity GO:0010950 26 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
negative regulation of rna metabolic process GO:0051253 251 0.029
spermatid development GO:0007286 98 0.028
nucleoside metabolic process GO:0009116 127 0.028
macromolecule catabolic process GO:0009057 161 0.028
compound eye development GO:0048749 307 0.028
renal system development GO:0072001 72 0.027
nucleotide metabolic process GO:0009117 161 0.027
Rat
nucleoside phosphate metabolic process GO:0006753 162 0.027
Rat
organophosphate metabolic process GO:0019637 195 0.027
Rat
single organism catabolic process GO:0044712 228 0.027
embryonic morphogenesis GO:0048598 206 0.027
apoptotic process GO:0006915 159 0.027
spermatogenesis GO:0007283 200 0.026
camera type eye development GO:0043010 4 0.026
chromatin organization GO:0006325 207 0.026
positive regulation of signal transduction GO:0009967 223 0.026
central nervous system development GO:0007417 201 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
death GO:0016265 284 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
cellular amine metabolic process GO:0044106 12 0.025
regionalization GO:0003002 416 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
regulation of proteolysis GO:0030162 87 0.024
response to glucose GO:0009749 2 0.024
kidney development GO:0001822 3 0.024
protein complex biogenesis GO:0070271 201 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
multicellular organismal aging GO:0010259 140 0.024
nitrogen compound transport GO:0071705 85 0.023
amine metabolic process GO:0009308 12 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
Human Yeast
positive regulation of cell death GO:0010942 69 0.023
ribonucleoside metabolic process GO:0009119 127 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
regulation of catalytic activity GO:0050790 185 0.022
carboxylic acid transport GO:0046942 18 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
brain development GO:0007420 120 0.022
regulation of cell morphogenesis GO:0022604 163 0.022
single organism biosynthetic process GO:0044711 206 0.022
Yeast
cell motility GO:0048870 251 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
dna metabolic process GO:0006259 227 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
cellular ketone metabolic process GO:0042180 24 0.021
regulation of cellular response to stress GO:0080135 89 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
protein complex assembly GO:0006461 200 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
regulation of organelle organization GO:0033043 196 0.020
cell proliferation GO:0008283 299 0.020
anion transport GO:0006820 41 0.020
multicellular organismal reproductive behavior GO:0033057 110 0.020
neurological system process GO:0050877 358 0.020
response to oxygen containing compound GO:1901700 200 0.019
single organism carbohydrate metabolic process GO:0044723 72 0.019
heterocycle catabolic process GO:0046700 166 0.019
positive regulation of cell migration GO:0030335 2 0.019
positive regulation of molecular function GO:0044093 136 0.018
disaccharide metabolic process GO:0005984 4 0.018
positive regulation of signaling GO:0023056 243 0.018
regulation of hydrolase activity GO:0051336 97 0.018
regulation of localization GO:0032879 275 0.018
cell migration GO:0016477 238 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
chromosome organization GO:0051276 360 0.018
regulation of cell death GO:0010941 173 0.018
cellularization GO:0007349 90 0.018
carbohydrate metabolic process GO:0005975 82 0.018
glycosaminoglycan catabolic process GO:0006027 3 0.018
aromatic amino acid family metabolic process GO:0009072 3 0.017
positive regulation of cell communication GO:0010647 250 0.017
spindle organization GO:0007051 253 0.017
regulation of protein modification process GO:0031399 112 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
rhythmic process GO:0048511 106 0.017
cell growth GO:0016049 108 0.017
organelle assembly GO:0070925 198 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
histolysis GO:0007559 102 0.016
regulation of cell differentiation GO:0045595 302 0.016
retina development in camera type eye GO:0060041 4 0.016
hematopoietic or lymphoid organ development GO:0048534 57 0.016
regulation of programmed cell death GO:0043067 152 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
regulation of catabolic process GO:0009894 170 0.016
positive regulation of peptidase activity GO:0010952 29 0.016
regulation of molecular function GO:0065009 217 0.016
mitotic spindle organization GO:0007052 220 0.016
localization of cell GO:0051674 257 0.016
epithelial cell differentiation GO:0030855 322 0.016
neutral lipid biosynthetic process GO:0046460 2 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
melanin metabolic process GO:0006582 47 0.015
blastoderm segmentation GO:0007350 159 0.015
chromatin modification GO:0016568 147 0.015
oxidation reduction process GO:0055114 123 0.015
Yeast
histone modification GO:0016570 106 0.015
cognition GO:0050890 141 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
response to hexose GO:0009746 3 0.015
positive regulation of apoptotic process GO:0043065 47 0.015
regulation of response to stress GO:0080134 200 0.015
negative regulation of gene expression GO:0010629 387 0.015
peptide metabolic process GO:0006518 80 0.015
eye morphogenesis GO:0048592 260 0.014
digestive tract development GO:0048565 149 0.014
regulation of reproductive process GO:2000241 54 0.014
regulation of multi organism process GO:0043900 131 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
regulation of cellular localization GO:0060341 136 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
establishment of localization in cell GO:0051649 402 0.014
kidney epithelium development GO:0072073 3 0.014
gland morphogenesis GO:0022612 145 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
aromatic compound catabolic process GO:0019439 166 0.014
negative regulation of developmental process GO:0051093 201 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
mrna metabolic process GO:0016071 124 0.014
regulation of endopeptidase activity GO:0052548 36 0.014
embryonic pattern specification GO:0009880 174 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
tube development GO:0035295 244 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
mapk cascade GO:0000165 107 0.013
homeostatic process GO:0042592 199 0.013
amino acid transport GO:0006865 12 0.013
negative regulation of cell communication GO:0010648 223 0.013
one carbon metabolic process GO:0006730 3 0.013
Rat
reproductive behavior GO:0019098 122 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
organic acid catabolic process GO:0016054 16 0.013
mating behavior GO:0007617 106 0.013
aging GO:0007568 143 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
alpha amino acid biosynthetic process GO:1901607 4 0.013
segmentation GO:0035282 207 0.013
mitotic nuclear division GO:0007067 213 0.013
tripartite regional subdivision GO:0007351 103 0.013
pyridine nucleotide metabolic process GO:0019362 2 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
lateral inhibition GO:0046331 206 0.013
response to lipopolysaccharide GO:0032496 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
hindbrain development GO:0030902 2 0.012
epithelium migration GO:0090132 148 0.012
cellular carbohydrate metabolic process GO:0044262 22 0.012
immune response GO:0006955 246 0.012
connective tissue development GO:0061448 3 0.012
nicotinamide nucleotide metabolic process GO:0046496 2 0.012
exocrine system development GO:0035272 162 0.012
epithelial cell development GO:0002064 274 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
adult locomotory behavior GO:0008344 76 0.012
histone acetylation GO:0016573 38 0.012
dendrite morphogenesis GO:0048813 199 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
negative regulation of cell cycle GO:0045786 116 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
protein localization GO:0008104 284 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
regulation of peptidase activity GO:0052547 39 0.012
positive regulation of cell motility GO:2000147 3 0.012
sulfur compound metabolic process GO:0006790 59 0.011
rna processing GO:0006396 147 0.011
anterior posterior pattern specification GO:0009952 136 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
leucine import GO:0060356 3 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
hemopoiesis GO:0030097 46 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
autophagy GO:0006914 108 0.011
phosphatidylinositol mediated signaling GO:0048015 4 0.011
protein processing GO:0016485 68 0.011
oxidoreduction coenzyme metabolic process GO:0006733 2 0.011
small molecule catabolic process GO:0044282 21 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
response to nitrogen compound GO:1901698 90 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
learning or memory GO:0007611 141 0.011
taxis GO:0042330 304 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
inositol lipid mediated signaling GO:0048017 4 0.011
ameboidal type cell migration GO:0001667 151 0.011
catechol containing compound biosynthetic process GO:0009713 3 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
axis specification GO:0009798 167 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
response to monosaccharide GO:0034284 4 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
detection of chemical stimulus GO:0009593 93 0.011
multi multicellular organism process GO:0044706 123 0.011
positive regulation of transcription dna templated GO:0045893 266 0.010
actin filament based process GO:0030029 220 0.010
cellular macromolecule localization GO:0070727 220 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
positive regulation of catabolic process GO:0009896 105 0.010
protein kinase b signaling GO:0043491 1 0.010
regulation of nervous system development GO:0051960 248 0.010
locomotory behavior GO:0007626 176 0.010
developmental maturation GO:0021700 172 0.010
spindle assembly GO:0051225 80 0.010
tube formation GO:0035148 21 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
memory GO:0007613 94 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
developmental growth GO:0048589 280 0.010
regulation of cysteine type endopeptidase activity GO:2000116 27 0.010
open tracheal system development GO:0007424 204 0.010
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010

pug disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
nervous system disease DOID:863 0 0.020