Drosophila melanogaster

52 known processes

svr (Dmel_CG4122)

silver

(Aliases: Dmel\CG4122,CG32818,cc,slv,EP(X)0356,CPD,CG4122,CpepE,dwp,l(1)1Bd,poi,EG:171D11.3,CG18503,CP)

svr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.658
appendage morphogenesis GO:0035107 397 0.404
post embryonic appendage morphogenesis GO:0035120 385 0.331
appendage development GO:0048736 401 0.299
imaginal disc derived wing vein specification GO:0007474 48 0.293
imaginal disc derived appendage development GO:0048737 399 0.286
wing disc morphogenesis GO:0007472 344 0.255
imaginal disc derived wing morphogenesis GO:0007476 337 0.241
vesicle mediated transport GO:0016192 381 0.182
negative regulation of erbb signaling pathway GO:1901185 29 0.164
immune effector process GO:0002252 98 0.112
negative regulation of receptor activity GO:2000272 3 0.110
bmp signaling pathway GO:0030509 27 0.091
negative regulation of cellular metabolic process GO:0031324 382 0.091
cognition GO:0050890 141 0.090
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.090
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.083
memory GO:0007613 94 0.083
learning or memory GO:0007611 141 0.082
regulation of phosphate metabolic process GO:0019220 210 0.080
regulation of bmp signaling pathway GO:0030510 23 0.077
positive regulation of cell communication GO:0010647 250 0.072
negative regulation of cell communication GO:0010648 223 0.071
negative regulation of insulin secretion GO:0046676 1 0.064
negative regulation of cellular biosynthetic process GO:0031327 277 0.061
immune response GO:0006955 246 0.058
amine metabolic process GO:0009308 12 0.057
hemopoiesis GO:0030097 46 0.056
macromolecule catabolic process GO:0009057 161 0.056
regulation of localization GO:0032879 275 0.056
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.054
body morphogenesis GO:0010171 2 0.053
regulation of catalytic activity GO:0050790 185 0.053
oocyte development GO:0048599 124 0.051
positive regulation of signaling GO:0023056 243 0.050
negative regulation of biosynthetic process GO:0009890 277 0.048
organonitrogen compound metabolic process GO:1901564 318 0.046
germ line stem cell maintenance GO:0030718 50 0.046
small molecule metabolic process GO:0044281 305 0.046
actin cytoskeleton organization GO:0030036 206 0.045
photoreceptor cell differentiation GO:0046530 170 0.045
negative regulation of cell differentiation GO:0045596 143 0.044
regulation of epidermal growth factor activated receptor activity GO:0007176 4 0.044
positive regulation of signal transduction GO:0009967 223 0.044
immune response regulating signaling pathway GO:0002764 2 0.043
regulation of protein metabolic process GO:0051246 256 0.043
immune response activating signal transduction GO:0002757 2 0.043
organic substance transport GO:0071702 257 0.042
oocyte maturation GO:0001556 3 0.041
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.041
regulation of cellular component size GO:0032535 98 0.039
regulation of extracellular matrix organization GO:1903053 4 0.039
cellular ketone metabolic process GO:0042180 24 0.038
aging GO:0007568 143 0.036
negative regulation of peptide hormone secretion GO:0090278 1 0.036
pigmentation GO:0043473 75 0.035
long term memory GO:0007616 62 0.034
cell cell junction organization GO:0045216 55 0.033
negative regulation of peptide secretion GO:0002792 1 0.033
epithelial cell migration GO:0010631 148 0.033
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
regulation of cellular component biogenesis GO:0044087 201 0.032
organic acid metabolic process GO:0006082 103 0.032
oxoacid metabolic process GO:0043436 103 0.032
immune system development GO:0002520 57 0.032
oocyte differentiation GO:0009994 145 0.031
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.031
regulation of transport GO:0051049 181 0.030
regulation of multicellular organismal development GO:2000026 414 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
single organism behavior GO:0044708 391 0.030
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.029
positive regulation of developmental growth GO:0048639 62 0.029
negative regulation of bmp signaling pathway GO:0030514 12 0.029
medium term memory GO:0072375 8 0.028
cellular protein modification process GO:0006464 438 0.027
developmental growth GO:0048589 280 0.027
learning GO:0007612 75 0.027
eye photoreceptor cell differentiation GO:0001754 145 0.027
endomembrane system organization GO:0010256 119 0.026
regulation of decapentaplegic signaling pathway GO:0090097 8 0.026
regulation of growth GO:0040008 233 0.026
connective tissue development GO:0061448 3 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
positive regulation of transport GO:0051050 92 0.024
regulation of erbb signaling pathway GO:1901184 42 0.024
regulation of molecular function GO:0065009 217 0.024
endocytosis GO:0006897 310 0.024
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
multicellular organism growth GO:0035264 46 0.023
regulation of imaginal disc growth GO:0045570 26 0.023
ion transport GO:0006811 145 0.023
response to organophosphorus GO:0046683 2 0.022
response to sterol GO:0036314 34 0.022
defense response GO:0006952 300 0.021
cellular amine metabolic process GO:0044106 12 0.021
response to other organism GO:0051707 293 0.021
negative regulation of gene expression GO:0010629 387 0.020
organic substance catabolic process GO:1901575 308 0.020
determination of adult lifespan GO:0008340 137 0.020
biological adhesion GO:0022610 138 0.020
protein complex biogenesis GO:0070271 201 0.020
immune system process GO:0002376 347 0.020
protein modification process GO:0036211 438 0.020
positive regulation of muscle organ development GO:0048636 6 0.019
regulation of immune system process GO:0002682 176 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.019
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.019
cell junction organization GO:0034330 57 0.019
single organism biosynthetic process GO:0044711 206 0.019
cellular macromolecular complex assembly GO:0034622 153 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
regulation of immune effector process GO:0002697 52 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
short term memory GO:0007614 19 0.018
camera type eye development GO:0043010 4 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.017
positive regulation of phagocytosis engulfment GO:0060100 1 0.017
proteolysis GO:0006508 192 0.017
instar larval development GO:0002168 55 0.017
protein complex assembly GO:0006461 200 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.016
eye development GO:0001654 323 0.016
secretion GO:0046903 109 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
dna biosynthetic process GO:0071897 24 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
maintenance of location GO:0051235 73 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
regulation of immune response GO:0050776 118 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
negative regulation of signaling GO:0023057 219 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
regulation of smoothened signaling pathway GO:0008589 28 0.015
multicellular organismal aging GO:0010259 140 0.015
protein transport GO:0015031 155 0.015
peptidyl tyrosine phosphorylation GO:0018108 24 0.015
regionalization GO:0003002 416 0.015
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.015
cell death GO:0008219 279 0.015
negative regulation of signal transduction GO:0009968 206 0.015
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.015
cellular protein complex assembly GO:0043623 71 0.014
larval development GO:0002164 104 0.014
Worm
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.014
multi multicellular organism process GO:0044706 123 0.014
response to alcohol GO:0097305 95 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
catabolic process GO:0009056 409 0.014
negative regulation of transcription dna templated GO:0045892 237 0.013
blastoderm segmentation GO:0007350 159 0.013
protein ubiquitination GO:0016567 70 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
epithelium migration GO:0090132 148 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
establishment of protein localization GO:0045184 163 0.013
epidermal cell differentiation GO:0009913 51 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
amide transport GO:0042886 10 0.013
regulation of hemocyte proliferation GO:0035206 37 0.013
epidermis development GO:0008544 65 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
lipid metabolic process GO:0006629 121 0.013
molting cycle GO:0042303 56 0.012
response to uv GO:0009411 24 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
regulation of phagocytosis engulfment GO:0060099 1 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
endoderm formation GO:0001706 3 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
tyrosine phosphorylation of stat protein GO:0007260 1 0.012
developmental pigmentation GO:0048066 68 0.012
positive regulation of ras gtpase activity GO:0032320 36 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
jak stat cascade GO:0007259 49 0.012
regulation of protein tyrosine kinase activity GO:0061097 9 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
response to endogenous stimulus GO:0009719 119 0.012
mrna metabolic process GO:0016071 124 0.011
histoblast morphogenesis GO:0007488 9 0.011
positive regulation of immune response GO:0050778 63 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
gastrulation GO:0007369 70 0.011
chorion containing eggshell formation GO:0007304 105 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
negative regulation of hormone biosynthetic process GO:0032353 1 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
gland development GO:0048732 191 0.011
regulation of organelle organization GO:0033043 196 0.011
nitrogen compound transport GO:0071705 85 0.011
secretion by cell GO:0032940 101 0.011
negative regulation of developmental process GO:0051093 201 0.011
negative regulation of molecular function GO:0044092 51 0.011
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.011
signal transduction downstream of smoothened GO:0007227 5 0.011
positive regulation of multicellular organism growth GO:0040018 21 0.011
compound eye development GO:0048749 307 0.010
positive regulation of histone deacetylation GO:0031065 2 0.010
adult chitin containing cuticle pigmentation GO:0048085 16 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
reproductive system development GO:0061458 74 0.010
eye morphogenesis GO:0048592 260 0.010
actin filament based process GO:0030029 220 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
regulation of cell differentiation GO:0045595 302 0.010
regulation of lipid transport GO:0032368 3 0.010
chemosensory behavior GO:0007635 106 0.010
germ line stem cell division GO:0042078 25 0.010

svr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.010