Drosophila melanogaster

47 known processes

rst (Dmel_CG4125)

roughest

(Aliases: Irre-C,irreC,irrecC-rst,irreC-rst,IrreC-Rst,Dmel\CG4125,IRREC/RST,IrreC/Rst,UB883,CG4125,rst/irrecC,IrrecC,IREE-C,rst-irrecC,Rst,IrreC-rst,CT13684,IrreC,rst-irreC)

rst biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myoblast fusion GO:0007520 43 0.999
Fly
syncytium formation by plasma membrane fusion GO:0000768 43 0.998
Fly
muscle cell differentiation GO:0042692 103 0.983
Fly
striated muscle cell differentiation GO:0051146 90 0.980
Fly
brain development GO:0007420 120 0.968
Mouse Fly
eye development GO:0001654 323 0.965
eye morphogenesis GO:0048592 260 0.964
syncytium formation GO:0006949 43 0.950
Fly
muscle structure development GO:0061061 224 0.946
regulation of anatomical structure morphogenesis GO:0022603 242 0.913
Fly
actin filament based process GO:0030029 220 0.906
Mouse Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.897
nephrocyte diaphragm assembly GO:0036059 3 0.879
Fly
establishment of tissue polarity GO:0007164 87 0.876
Fly
ommatidial rotation GO:0016318 20 0.871
head development GO:0060322 135 0.862
Mouse Fly
extracellular structure organization GO:0043062 46 0.859
Zebrafish
negative regulation of signal transduction GO:0009968 206 0.857
Fly
tube morphogenesis GO:0035239 191 0.836
Fly
renal tubule development GO:0061326 64 0.831
Fly
positive regulation of endopeptidase activity GO:0010950 26 0.826
Fly
regulation of organ growth GO:0046620 42 0.820
Fly
regulation of multicellular organismal development GO:2000026 414 0.814
myotube differentiation GO:0014902 46 0.804
Fly
respiratory system development GO:0060541 213 0.803
Fly
establishment of planar polarity GO:0001736 87 0.787
Fly
branching morphogenesis of an epithelial tube GO:0048754 45 0.787
Fly
regulation of cell differentiation GO:0045595 302 0.781
Fly
kidney development GO:0001822 3 0.759
Zebrafish Mouse
central nervous system development GO:0007417 201 0.743
Mouse Fly
nephron development GO:0072006 3 0.722
Zebrafish Mouse
negative regulation of cell communication GO:0010648 223 0.713
Fly
positive regulation of peptidase activity GO:0010952 29 0.713
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.713
Fly
eye photoreceptor cell differentiation GO:0001754 145 0.702
Fly
compound eye development GO:0048749 307 0.699
morphogenesis of a polarized epithelium GO:0001738 93 0.679
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.672
Fly
morphogenesis of a branching epithelium GO:0061138 45 0.665
Fly
actin filament bundle assembly GO:0051017 26 0.656
Fly
actin filament organization GO:0007015 126 0.651
Mouse Fly
segmentation GO:0035282 207 0.636
filtration diaphragm assembly GO:0036058 4 0.635
Fly
adherens junction assembly GO:0034333 11 0.633
Fly
fusion cell fate specification GO:0035156 4 0.622
Fly
regulation of organ morphogenesis GO:2000027 78 0.614
regulation of neuron differentiation GO:0045664 103 0.606
morphogenesis of an epithelium GO:0002009 276 0.573
Fly
epithelial tube morphogenesis GO:0060562 88 0.561
Fly
eggshell formation GO:0030703 105 0.554
Fly
regulation of endopeptidase activity GO:0052548 36 0.552
Fly
regulation of cell development GO:0060284 215 0.551
Fly
axonogenesis GO:0007409 290 0.550
open tracheal system development GO:0007424 204 0.540
Fly
tissue morphogenesis GO:0048729 297 0.537
Fly
skeletal muscle fiber development GO:0048741 3 0.536
somatic muscle development GO:0007525 66 0.531
post embryonic appendage morphogenesis GO:0035120 385 0.526
Fly
compound eye morphogenesis GO:0001745 249 0.519
regulation of programmed cell death GO:0043067 152 0.514
adult chitin based cuticle development GO:0008365 2 0.498
Fly
gland development GO:0048732 191 0.493
regulation of nervous system development GO:0051960 248 0.482
Fly
adult chitin based cuticle pattern formation GO:0035018 1 0.475
Fly
positive regulation of signaling GO:0023056 243 0.471
Fly
imaginal disc derived appendage development GO:0048737 399 0.463
Fly
negative regulation of response to stimulus GO:0048585 258 0.462
Fly
positive regulation of rna metabolic process GO:0051254 271 0.462
cellular macromolecule localization GO:0070727 220 0.459
cell adhesion GO:0007155 136 0.458
compound eye photoreceptor cell differentiation GO:0001751 140 0.453
Fly
axon guidance GO:0007411 233 0.443
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.439
establishment of ommatidial planar polarity GO:0042067 49 0.431
Fly
appendage morphogenesis GO:0035107 397 0.429
Fly
protein localization GO:0008104 284 0.428
myotube cell development GO:0014904 3 0.427
regulation of phosphorylation GO:0042325 147 0.416
Mouse
sensory organ morphogenesis GO:0090596 260 0.413
regulation of anatomical structure size GO:0090066 163 0.406
Mouse
regulation of cell fate specification GO:0042659 27 0.406
Fly
regulation of cell morphogenesis GO:0022604 163 0.402
Fly
positive regulation of cell development GO:0010720 61 0.401
muscle organ development GO:0007517 127 0.396
cellular protein localization GO:0034613 160 0.391
ovarian follicle cell development GO:0030707 248 0.390
Fly
neuron projection guidance GO:0097485 241 0.389
photoreceptor cell differentiation GO:0046530 170 0.389
Fly
immune response GO:0006955 246 0.383
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.383
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.376
regulation of myoblast fusion GO:1901739 6 0.375
Fly
stem cell proliferation GO:0072089 88 0.373
actin cytoskeleton organization GO:0030036 206 0.370
Mouse Fly
proteolysis GO:0006508 192 0.367
Fly
oocyte differentiation GO:0009994 145 0.352
dorsal closure GO:0007391 79 0.348
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.343
growth GO:0040007 359 0.332
Fly
single organism cell adhesion GO:0098602 47 0.330
Mouse Fly
single organismal cell cell adhesion GO:0016337 45 0.323
Mouse Fly
notch receptor processing GO:0007220 13 0.320
Fly
actin filament bundle organization GO:0061572 28 0.320
Fly
protein modification by small protein conjugation GO:0032446 79 0.317
negative regulation of multicellular organismal process GO:0051241 142 0.295
Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.289
Fly
regulation of protein metabolic process GO:0051246 256 0.285
Mouse Fly
lateral inhibition GO:0046331 206 0.284
kidney epithelium development GO:0072073 3 0.282
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 368 0.272
regulation of neurogenesis GO:0050767 158 0.264
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.263
Mouse
regulation of cellular component size GO:0032535 98 0.254
Mouse
axon development GO:0061564 297 0.254
taxis GO:0042330 304 0.254
regulation of immune system process GO:0002682 176 0.253
chorion containing eggshell formation GO:0007304 105 0.251
Fly
urogenital system development GO:0001655 72 0.248
Zebrafish Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.246
Fly
cell fate specification GO:0001708 71 0.246
Fly
regulation of neuron projection development GO:0010975 69 0.245
protein modification by small protein conjugation or removal GO:0070647 106 0.242
regulation of epithelial cell proliferation GO:0050678 4 0.241
nephron epithelium development GO:0072009 3 0.239
Zebrafish
dendrite morphogenesis GO:0048813 199 0.231
negative regulation of neurogenesis GO:0050768 53 0.228
Fly
muscle tissue development GO:0060537 30 0.219
epithelial cell differentiation GO:0030855 322 0.218
Zebrafish Fly
organ growth GO:0035265 56 0.212
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.212
Mouse
notch signaling pathway GO:0007219 120 0.209
Fly
cell proliferation GO:0008283 299 0.209
wing disc morphogenesis GO:0007472 344 0.203
Fly
intracellular signal transduction GO:0035556 300 0.202
Fly
skin development GO:0043588 65 0.200
striated muscle tissue development GO:0014706 27 0.200
regulation of proteolysis GO:0030162 87 0.197
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.197
Fly
tube development GO:0035295 244 0.197
Zebrafish Fly
spermatogenesis GO:0007283 200 0.195
Fly
protein ubiquitination GO:0016567 70 0.192
regulation of peptidase activity GO:0052547 39 0.186
Fly
epithelial cell proliferation GO:0050673 15 0.185
establishment of localization in cell GO:0051649 402 0.181
germ band shortening GO:0007390 19 0.180
regulation of wnt signaling pathway GO:0030111 68 0.178
protein complex biogenesis GO:0070271 201 0.175
Mouse
regulation of myotube differentiation GO:0010830 6 0.173
Fly
renal system development GO:0072001 72 0.173
Zebrafish Mouse Fly
embryonic organ development GO:0048568 50 0.170
hemopoiesis GO:0030097 46 0.168
Mouse
regulation of photoreceptor cell differentiation GO:0046532 34 0.168
immune effector process GO:0002252 98 0.167
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8 0.166
Fly
regulation of response to external stimulus GO:0032101 115 0.164
regulation of catalytic activity GO:0050790 185 0.162
Fly
regionalization GO:0003002 416 0.161
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.160
Fly
dendrite development GO:0016358 204 0.158
neuron migration GO:0001764 5 0.157
Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.156
extracellular matrix organization GO:0030198 32 0.152
Zebrafish
morphogenesis of a branching structure GO:0001763 45 0.152
Worm Fly
embryonic pattern specification GO:0009880 174 0.151
negative regulation of epithelial cell proliferation GO:0050680 4 0.150
cell cell adhesion GO:0098609 26 0.149
cellular response to oxygen containing compound GO:1901701 79 0.147
contractile actin filament bundle assembly GO:0030038 1 0.147
Fly
positive regulation of signal transduction GO:0009967 223 0.145
Fly
neuron fate commitment GO:0048663 50 0.142
appendage development GO:0048736 401 0.140
Fly
apoptotic process GO:0006915 159 0.138
visceral muscle development GO:0007522 14 0.136
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.135
biological adhesion GO:0022610 138 0.134
positive regulation of response to stimulus GO:0048584 323 0.130
Fly
negative regulation of cell differentiation GO:0045596 143 0.130
Fly
regulation of actin cytoskeleton organization GO:0032956 42 0.130
Mouse Fly
salivary gland morphogenesis GO:0007435 145 0.127
imaginal disc derived appendage morphogenesis GO:0035114 395 0.127
Fly
regulation of actin filament based process GO:0032970 42 0.126
Mouse Fly
embryonic morphogenesis GO:0048598 206 0.126
Fly
positive regulation of cell projection organization GO:0031346 29 0.126
larval development GO:0002164 104 0.125
Fly
regulation of cell size GO:0008361 63 0.124
cuticle pattern formation GO:0035017 27 0.122
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.121
Mouse Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.121
Fly
regulation of cell fate commitment GO:0010453 29 0.121
Fly
wnt signaling pathway GO:0016055 98 0.121
regulation of actin polymerization or depolymerization GO:0008064 27 0.120
Mouse
death GO:0016265 284 0.119
camera type eye development GO:0043010 4 0.119
positive regulation of biosynthetic process GO:0009891 316 0.118
regulation of r7 cell differentiation GO:0045676 15 0.117
positive regulation of gene expression GO:0010628 290 0.116
positive regulation of cellular protein metabolic process GO:0032270 118 0.115
Fly
response to wounding GO:0009611 94 0.115
Fly
larval visceral muscle development GO:0007523 9 0.115
Fly
negative regulation of fusion cell fate specification GO:0035157 2 0.115
Fly
regulation of defense response GO:0031347 102 0.111
regulation of molecular function GO:0065009 217 0.111
Fly
regulation of apoptotic signaling pathway GO:2001233 10 0.111
regulation of protein localization GO:0032880 76 0.110
positive regulation of transcription dna templated GO:0045893 266 0.110
cell cell junction organization GO:0045216 55 0.109
Fly
specification of organ identity GO:0010092 3 0.108
hematopoietic or lymphoid organ development GO:0048534 57 0.108
Mouse
negative regulation of gene expression GO:0010629 387 0.107
compound eye photoreceptor fate commitment GO:0001752 36 0.107
negative regulation of cell development GO:0010721 62 0.106
Fly
organophosphate metabolic process GO:0019637 195 0.105
hindbrain development GO:0030902 2 0.104
positive regulation of developmental process GO:0051094 143 0.101
positive regulation of cell differentiation GO:0045597 64 0.101
epithelial cell type specification open tracheal system GO:0035153 11 0.101
Fly
positive regulation of hydrolase activity GO:0051345 78 0.099
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.098
secretion GO:0046903 109 0.097
regulation of cellular component biogenesis GO:0044087 201 0.097
Mouse
malpighian tubule morphogenesis GO:0007443 44 0.096
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.094
Fly
single organism catabolic process GO:0044712 228 0.093
regulation of cell death GO:0010941 173 0.093
compound eye retinal cell programmed cell death GO:0046667 23 0.093
synapse organization GO:0050808 196 0.093
Worm
chromosome organization GO:0051276 360 0.092
negative regulation of developmental process GO:0051093 201 0.092
Fly
positive regulation of cell death GO:0010942 69 0.092
actin filament polymerization GO:0030041 27 0.090
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.090
Mouse
mapk cascade GO:0000165 107 0.090
nucleobase containing small molecule metabolic process GO:0055086 174 0.090
positive regulation of programmed cell death GO:0043068 62 0.089
extrinsic apoptotic signaling pathway GO:0097191 1 0.087
cell death GO:0008219 279 0.087
regulation of muscle tissue development GO:1901861 5 0.087
peptidyl amino acid modification GO:0018193 105 0.085
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.085
cuticle development GO:0042335 86 0.084
Fly
negative regulation of protein phosphorylation GO:0001933 17 0.084
Mouse
secretion by cell GO:0032940 101 0.083
genital disc development GO:0035215 44 0.078
cellular protein modification process GO:0006464 438 0.078
Mouse
negative regulation of cell cycle process GO:0010948 109 0.077
hippo signaling GO:0035329 20 0.076
Fly
mushroom body development GO:0016319 70 0.075
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.075
Fly
regulation of actin filament polymerization GO:0030833 25 0.074
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.074
Fly
regulation of cysteine type endopeptidase activity GO:2000116 27 0.074
malpighian tubule development GO:0072002 64 0.073
Fly
stem cell maintenance GO:0019827 67 0.072
positive regulation of proteolysis GO:0045862 52 0.071
Fly
regulation of immune response GO:0050776 118 0.069
protein maturation GO:0051604 71 0.069
immune system process GO:0002376 347 0.069
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.069
protein complex assembly GO:0006461 200 0.068
Mouse
regulation of response to stress GO:0080134 200 0.068
eye photoreceptor cell fate commitment GO:0042706 37 0.068
response to nutrient levels GO:0031667 114 0.067
cellular protein complex assembly GO:0043623 71 0.067
Mouse
protein modification process GO:0036211 438 0.067
Mouse
telencephalon development GO:0021537 2 0.067
mesoderm development GO:0007498 78 0.066
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.066
regulation of protein phosphorylation GO:0001932 64 0.066
Mouse
aging GO:0007568 143 0.064
eggshell chorion assembly GO:0007306 66 0.064
Fly
regulation of cell cell adhesion GO:0022407 21 0.064
positive regulation of nucleic acid templated transcription GO:1903508 266 0.063
negative regulation of developmental growth GO:0048640 64 0.063
Fly
stress activated protein kinase signaling cascade GO:0031098 55 0.063
programmed cell death GO:0012501 257 0.063
posttranscriptional regulation of gene expression GO:0010608 145 0.063
forebrain development GO:0030900 2 0.063
positive regulation of neuron differentiation GO:0045666 26 0.062
maintenance of location GO:0051235 73 0.060
cell division GO:0051301 248 0.060
negative regulation of nucleic acid templated transcription GO:1903507 240 0.060
regulation of protein kinase activity GO:0045859 51 0.060
negative regulation of cell death GO:0060548 81 0.060
inter male aggressive behavior GO:0002121 60 0.059
Mouse Fly
regulation of transferase activity GO:0051338 58 0.059
regulation of cytoskeleton organization GO:0051493 89 0.057
Mouse Fly
negative regulation of cellular protein metabolic process GO:0032269 85 0.057
Mouse
regulation of synapse structure and activity GO:0050803 128 0.056
regulation of hydrolase activity GO:0051336 97 0.056
Fly
inositol lipid mediated signaling GO:0048017 4 0.056
multi organism behavior GO:0051705 175 0.055
Mouse Fly
substrate dependent cell migration GO:0006929 3 0.054
eye photoreceptor cell development GO:0042462 81 0.053
chaeta development GO:0022416 97 0.052
regulation of growth GO:0040008 233 0.052
Fly
centrosome duplication GO:0051298 121 0.052
anterior posterior pattern specification GO:0009952 136 0.051
regulation of localization GO:0032879 275 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.051
positive regulation of immune system process GO:0002684 68 0.051
digestive tract morphogenesis GO:0048546 127 0.050
negative regulation of signaling GO:0023057 219 0.050
Fly
positive regulation of neuron apoptotic process GO:0043525 1 0.050
negative regulation of rna biosynthetic process GO:1902679 240 0.049
establishment or maintenance of cell polarity GO:0007163 167 0.049
Fly
response to organic substance GO:0010033 284 0.049
regulation of striated muscle tissue development GO:0016202 5 0.049
regulation of dendrite morphogenesis GO:0048814 28 0.049
endodermal cell fate commitment GO:0001711 3 0.048
defense response GO:0006952 300 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.047
positive regulation of developmental growth GO:0048639 62 0.047
compound eye photoreceptor development GO:0042051 78 0.047
pigmentation GO:0043473 75 0.046
glutamate secretion GO:0014047 1 0.046
cellular catabolic process GO:0044248 372 0.046
purine containing compound metabolic process GO:0072521 155 0.045
chemotaxis GO:0006935 249 0.045
regulation of smoothened signaling pathway GO:0008589 28 0.045
positive regulation of cell communication GO:0010647 250 0.044
Fly
regulation of erbb signaling pathway GO:1901184 42 0.044
Fly
protein processing GO:0016485 68 0.044
cell maturation GO:0048469 144 0.044
regulation of muscle organ development GO:0048634 13 0.043
axis specification GO:0009798 167 0.043
innate immune response GO:0045087 144 0.043
camera type eye morphogenesis GO:0048593 2 0.043
membrane organization GO:0061024 112 0.043
developmental growth GO:0048589 280 0.042
Fly
salivary gland development GO:0007431 162 0.042
positive regulation of cellular biosynthetic process GO:0031328 316 0.042
compound eye cone cell differentiation GO:0042675 13 0.042
blastoderm segmentation GO:0007350 159 0.042
circadian rhythm GO:0007623 105 0.042
epithelial cell development GO:0002064 274 0.042
Zebrafish Fly
heart development GO:0007507 82 0.042
regulation of cell cycle process GO:0010564 181 0.041
vesicle mediated transport GO:0016192 381 0.041
regulation of cellular ketone metabolic process GO:0010565 3 0.041
regulation of apoptotic process GO:0042981 130 0.040
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.039
positive regulation of cell migration GO:0030335 2 0.039
regulation of cell adhesion GO:0030155 27 0.039
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.039
positive regulation of cell motility GO:2000147 3 0.039
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.039
Fly
organonitrogen compound metabolic process GO:1901564 318 0.039
skeletal muscle organ development GO:0060538 48 0.039
cell cycle phase transition GO:0044770 140 0.038
negative regulation of biosynthetic process GO:0009890 277 0.038
endocytosis GO:0006897 310 0.038
developmental maturation GO:0021700 172 0.038
stem cell development GO:0048864 79 0.038
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.037
Fly
organic substance transport GO:0071702 257 0.037
phosphorylation GO:0016310 294 0.037
Mouse
cellular macromolecular complex assembly GO:0034622 153 0.037
Mouse
response to abiotic stimulus GO:0009628 341 0.037
regulation of intracellular signal transduction GO:1902531 236 0.036
Fly
negative regulation of programmed cell death GO:0043069 72 0.036
leg disc morphogenesis GO:0007478 80 0.036
retina development in camera type eye GO:0060041 4 0.036
regulation of striated muscle cell differentiation GO:0051153 8 0.036
Fly
cell junction assembly GO:0034329 42 0.035
Fly
negative regulation of cell cell adhesion GO:0022408 8 0.035
regulation of cellular amine metabolic process GO:0033238 3 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
regulation of mitotic cell cycle phase transition GO:1901990 130 0.035
positive regulation of protein kinase activity GO:0045860 25 0.035
regulation of cell shape GO:0008360 113 0.035
Fly
catabolic process GO:0009056 409 0.035
positive regulation of nervous system development GO:0051962 69 0.034
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.034
microtubule organizing center organization GO:0031023 168 0.034
positive regulation of phosphorus metabolic process GO:0010562 139 0.034
regulation of circadian rhythm GO:0042752 49 0.034
canonical wnt signaling pathway GO:0060070 21 0.034
imaginal disc derived wing vein specification GO:0007474 48 0.033
cell cell junction assembly GO:0007043 38 0.033
Fly
regulation of developmental growth GO:0048638 174 0.033
Fly
nephrocyte differentiation GO:0061319 12 0.033
Fly
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.033
determination of adult lifespan GO:0008340 137 0.033
branching involved in open tracheal system development GO:0060446 45 0.033
Fly
organic substance catabolic process GO:1901575 308 0.033
regulation of protein transport GO:0051223 57 0.032
negative regulation of catalytic activity GO:0043086 42 0.032
immune system development GO:0002520 57 0.032
Mouse
regeneration GO:0031099 16 0.032
ribonucleoside metabolic process GO:0009119 127 0.032
positive regulation of apoptotic process GO:0043065 47 0.032
endomembrane system organization GO:0010256 119 0.032
kidney morphogenesis GO:0060993 3 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.032
positive regulation of cellular component biogenesis GO:0044089 80 0.032
Mouse
cellular response to dna damage stimulus GO:0006974 223 0.032
nucleoside metabolic process GO:0009116 127 0.031
negative regulation of growth GO:0045926 84 0.031
Fly
positive regulation of protein complex assembly GO:0031334 22 0.031
Mouse
positive regulation of muscle organ development GO:0048636 6 0.031
regulation of eye photoreceptor cell development GO:0042478 13 0.031
regulation of cell cycle phase transition GO:1901987 130 0.031
eye antennal disc development GO:0035214 60 0.031
jnk cascade GO:0007254 50 0.030
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.030
positive regulation of protein modification process GO:0031401 58 0.030
regulation of cellular component movement GO:0051270 42 0.030
protein localization to organelle GO:0033365 82 0.030
renal filtration GO:0097205 7 0.030
Fly
regulation of compound eye photoreceptor development GO:0045314 12 0.029
regulation of imaginal disc growth GO:0045570 26 0.029
nuclear division GO:0000280 332 0.029
cell fate determination GO:0001709 91 0.029
reproductive structure development GO:0048608 74 0.029
regulation of cell motility GO:2000145 23 0.029
regulation of canonical wnt signaling pathway GO:0060828 15 0.029
germarium derived egg chamber formation GO:0007293 101 0.029
regulation of muscle cell differentiation GO:0051147 8 0.029
Fly
stress activated mapk cascade GO:0051403 52 0.028
amine metabolic process GO:0009308 12 0.028
intracellular transport GO:0046907 228 0.028
nucleus localization GO:0051647 34 0.028
phosphatidylinositol mediated signaling GO:0048015 4 0.028
cellular response to organic substance GO:0071310 132 0.028
cell growth GO:0016049 108 0.028
wing disc pattern formation GO:0035222 66 0.028
wound healing GO:0042060 75 0.028
Fly
regulation of protein modification process GO:0031399 112 0.028
Mouse
smoothened signaling pathway GO:0007224 49 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.028
regulation of syncytium formation by plasma membrane fusion GO:0060142 6 0.028
Fly
positive regulation of protein phosphorylation GO:0001934 34 0.028
positive regulation of kinase activity GO:0033674 25 0.028
negative regulation of phosphate metabolic process GO:0045936 45 0.028
Mouse
regulation of secretion GO:0051046 44 0.027
dna metabolic process GO:0006259 227 0.027
regulation of axonogenesis GO:0050770 32 0.027
protein catabolic process GO:0030163 101 0.026
regulation of actin filament length GO:0030832 27 0.026
Mouse
negative regulation of hippo signaling GO:0035331 5 0.026
Fly
regulation of cellular response to growth factor stimulus GO:0090287 13 0.026
cellular response to endogenous stimulus GO:0071495 80 0.026
regulation of mitosis GO:0007088 56 0.025
positive regulation of transferase activity GO:0051347 26 0.025
regulation of chemotaxis GO:0050920 12 0.025
single organism membrane organization GO:0044802 93 0.025
regulation of cell cycle GO:0051726 291 0.025
positive regulation of neuron projection development GO:0010976 14 0.025
establishment of protein localization GO:0045184 163 0.025
monocarboxylic acid transport GO:0015718 3 0.025
endodermal cell differentiation GO:0035987 3 0.024
macromolecule catabolic process GO:0009057 161 0.024
tripartite regional subdivision GO:0007351 103 0.024
branch fusion open tracheal system GO:0035147 17 0.024
Fly
cell projection assembly GO:0030031 94 0.024
oxoacid metabolic process GO:0043436 103 0.024
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
sensory perception of mechanical stimulus GO:0050954 72 0.023
regulation of cell migration GO:0030334 22 0.023
leg disc development GO:0035218 92 0.023
renal tubule morphogenesis GO:0061333 44 0.023
cellular protein catabolic process GO:0044257 83 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
cell type specific apoptotic process GO:0097285 38 0.023
protein phosphorylation GO:0006468 169 0.023
Mouse
regulation of dendrite development GO:0050773 37 0.023
positive regulation of neurogenesis GO:0050769 41 0.023
mitotic cell cycle phase transition GO:0044772 138 0.023
negative regulation of cellular component organization GO:0051129 108 0.022
digestive system development GO:0055123 149 0.022
cellular amide metabolic process GO:0043603 80 0.022
protein polymerization GO:0051258 42 0.022
Mouse
mitotic sister chromatid segregation GO:0000070 87 0.022
actin polymerization or depolymerization GO:0008154 31 0.022
Mouse
regulation of cellular localization GO:0060341 136 0.022
regulation of catabolic process GO:0009894 170 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
Fly
homeostatic process GO:0042592 199 0.022
cellular response to chemical stimulus GO:0070887 199 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
Fly
axon extension GO:0048675 32 0.021
negative regulation of apoptotic process GO:0043066 63 0.021
positive regulation of r7 cell differentiation GO:0045678 7 0.021
positive regulation of mapk cascade GO:0043410 63 0.021
negative regulation of wnt signaling pathway GO:0030178 28 0.021
regulation of cell growth GO:0001558 43 0.021
organic acid metabolic process GO:0006082 103 0.021
regulation of autophagy GO:0010506 62 0.021
positive regulation of response to external stimulus GO:0032103 44 0.021
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.021
cell aging GO:0007569 2 0.021

rst disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.098
cardiovascular system disease DOID:1287 0 0.029
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027