Drosophila melanogaster

37 known processes

Hsc70-3 (Dmel_CG4147)

Heat shock protein cognate 3

(Aliases: Hsc70,Hsc-70-3,Dmel\CG4147,CG1579,Hsc-3,l(1)G0466,BiP,l(1)G0407,hsc72,HSC70,hsc70,l(1)G0111,CG4147,dhsc70,hsc70-3,Bip,l(1)G0292,l(1)G0341,Hsc3p,HSC3,Grp78,bip,anon-WO0138581.7,Hsc3,l(1)G0102,dmHsc72,hsc3,HSC-70)

Hsc70-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 358 0.407
intracellular transport GO:0046907 228 0.345
Yeast
regulation of tube size GO:0035150 46 0.266
exocrine system development GO:0035272 162 0.228
cell death GO:0008219 279 0.210
Human
sensory perception of chemical stimulus GO:0007606 116 0.185
immune system process GO:0002376 347 0.171
organic substance transport GO:0071702 257 0.167
Yeast
taxis GO:0042330 304 0.153
sensory perception of smell GO:0007608 80 0.141
vesicle mediated transport GO:0016192 381 0.141
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.141
developmental programmed cell death GO:0010623 138 0.139
phagocytosis GO:0006909 215 0.137
programmed cell death GO:0012501 257 0.128
Human
developmental maturation GO:0021700 172 0.125
single organism intracellular transport GO:1902582 207 0.122
Yeast
compound eye development GO:0048749 307 0.121
spermatogenesis GO:0007283 200 0.117
negative regulation of cell communication GO:0010648 223 0.115
protein transport GO:0015031 155 0.115
Yeast
axis specification GO:0009798 167 0.109
male gamete generation GO:0048232 201 0.108
protein catabolic process GO:0030163 101 0.104
Yeast
eye development GO:0001654 323 0.103
organic substance catabolic process GO:1901575 308 0.102
Yeast
locomotory behavior GO:0007626 176 0.095
protein localization GO:0008104 284 0.093
Human Yeast
neuron remodeling GO:0016322 29 0.092
central nervous system development GO:0007417 201 0.091
Human
aging GO:0007568 143 0.089
death GO:0016265 284 0.088
Human
embryonic pattern specification GO:0009880 174 0.087
lateral inhibition GO:0046331 206 0.085
cation homeostasis GO:0055080 51 0.083
dorsal ventral pattern formation GO:0009953 133 0.083
cytoplasmic transport GO:0016482 130 0.080
Yeast
larval development GO:0002164 104 0.079
secretion by cell GO:0032940 101 0.079
catabolic process GO:0009056 409 0.079
Yeast
meiotic cell cycle process GO:1903046 132 0.078
transcription from rna polymerase ii promoter GO:0006366 368 0.078
spermatid differentiation GO:0048515 114 0.077
negative regulation of signaling GO:0023057 219 0.075
secretion GO:0046903 109 0.075
cellular response to dna damage stimulus GO:0006974 223 0.075
salivary gland development GO:0007431 162 0.075
microtubule based movement GO:0007018 51 0.074
endocytosis GO:0006897 310 0.074
positive regulation of wnt signaling pathway GO:0030177 25 0.073
copper ion homeostasis GO:0055070 7 0.072
gland morphogenesis GO:0022612 145 0.072
axon guidance GO:0007411 233 0.072
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.070
establishment of localization in cell GO:0051649 402 0.069
Yeast
detection of stimulus GO:0051606 156 0.069
sensory organ morphogenesis GO:0090596 260 0.068
positive regulation of axon guidance GO:1902669 1 0.067
regulation of localization GO:0032879 275 0.065
Human
gland development GO:0048732 191 0.063
tripartite regional subdivision GO:0007351 103 0.061
response to external biotic stimulus GO:0043207 293 0.061
tissue death GO:0016271 102 0.061
positive regulation of rna biosynthetic process GO:1902680 266 0.060
cellular chemical homeostasis GO:0055082 40 0.059
cellular protein localization GO:0034613 160 0.057
Human Yeast
salivary gland cell autophagic cell death GO:0035071 83 0.056
regulation of transport GO:0051049 181 0.056
organonitrogen compound metabolic process GO:1901564 318 0.056
Yeast
eye morphogenesis GO:0048592 260 0.056
molting cycle chitin based cuticle GO:0007591 56 0.054
response to nutrient levels GO:0031667 114 0.054
Human
response to anesthetic GO:0072347 9 0.052
posttranscriptional gene silencing by rna GO:0035194 45 0.052
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.052
Yeast
transition metal ion homeostasis GO:0055076 17 0.051
brain development GO:0007420 120 0.051
Human
dendrite morphogenesis GO:0048813 199 0.051
salivary gland histolysis GO:0035070 88 0.050
embryo development ending in birth or egg hatching GO:0009792 152 0.049
sensory perception GO:0007600 196 0.049
vesicle organization GO:0016050 44 0.048
negative regulation of signal transduction GO:0009968 206 0.048
histolysis GO:0007559 102 0.048
sensory perception of mechanical stimulus GO:0050954 72 0.047
posttranscriptional gene silencing GO:0016441 46 0.047
nucleobase containing compound catabolic process GO:0034655 165 0.047
Yeast
modification dependent macromolecule catabolic process GO:0043632 79 0.046
Yeast
epithelial cell differentiation GO:0030855 322 0.046
cellular response to starvation GO:0009267 61 0.045
Human
blastoderm segmentation GO:0007350 159 0.045
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.045
embryonic morphogenesis GO:0048598 206 0.044
l amino acid import GO:0043092 2 0.043
regionalization GO:0003002 416 0.043
cellular homeostasis GO:0019725 80 0.043
proteolysis GO:0006508 192 0.043
Yeast
positive regulation of gene expression GO:0010628 290 0.042
aggressive behavior GO:0002118 63 0.041
lipid localization GO:0010876 54 0.041
autophagic cell death GO:0048102 83 0.041
multi organism behavior GO:0051705 175 0.040
regulation of mitotic cell cycle GO:0007346 190 0.040
terminal region determination GO:0007362 25 0.040
cellular catabolic process GO:0044248 372 0.039
Yeast
glutamine metabolic process GO:0006541 4 0.039
cellular macromolecule localization GO:0070727 220 0.039
Human Yeast
sodium dependent phosphate transport GO:0044341 2 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.038
carboxylic acid metabolic process GO:0019752 92 0.038
limb morphogenesis GO:0035108 1 0.037
appendage development GO:0048736 401 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
adult behavior GO:0030534 137 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.035
hindbrain development GO:0030902 2 0.035
gliogenesis GO:0042063 80 0.035
salivary gland morphogenesis GO:0007435 145 0.035
cellular nitrogen compound catabolic process GO:0044270 165 0.035
Yeast
notch signaling pathway GO:0007219 120 0.035
regulation of immune system process GO:0002682 176 0.034
forebrain development GO:0030900 2 0.034
eye photoreceptor cell differentiation GO:0001754 145 0.034
response to temperature stimulus GO:0009266 106 0.034
chemotaxis GO:0006935 249 0.033
membrane organization GO:0061024 112 0.033
Yeast
negative regulation of response to stimulus GO:0048585 258 0.033
cell cycle g1 s phase transition GO:0044843 31 0.033
dendrite development GO:0016358 204 0.032
regulation of cell cycle GO:0051726 291 0.032
anterior posterior axis specification embryo GO:0008595 103 0.032
cellularization GO:0007349 90 0.032
mitotic dna integrity checkpoint GO:0044774 75 0.031
axon cargo transport GO:0008088 29 0.031
defense response GO:0006952 300 0.030
tissue morphogenesis GO:0048729 297 0.030
positive regulation of response to external stimulus GO:0032103 44 0.030
signal release GO:0023061 49 0.030
molting cycle GO:0042303 56 0.030
regulation of tube length open tracheal system GO:0035159 24 0.030
wnt signaling pathway GO:0016055 98 0.030
protein acylation GO:0043543 42 0.029
developmental growth GO:0048589 280 0.029
small molecule metabolic process GO:0044281 305 0.029
Yeast
cell maturation GO:0048469 144 0.029
organic hydroxy compound metabolic process GO:1901615 83 0.029
amino acid transport GO:0006865 12 0.028
molting cycle process GO:0022404 29 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.028
Yeast
regulation of glial cell proliferation GO:0060251 11 0.028
microtubule based transport GO:0010970 42 0.027
positive regulation of rna metabolic process GO:0051254 271 0.027
stress activated protein kinase signaling cascade GO:0031098 55 0.027
positive regulation of execution phase of apoptosis GO:1900119 4 0.027
morphogenesis of embryonic epithelium GO:0016331 94 0.027
response to endogenous stimulus GO:0009719 119 0.027
aromatic compound catabolic process GO:0019439 166 0.027
Yeast
compound eye morphogenesis GO:0001745 249 0.027
gene silencing by rna GO:0031047 57 0.027
semaphorin plexin signaling pathway GO:0071526 4 0.026
response to starvation GO:0042594 97 0.026
Human
regulation of cellular response to stress GO:0080135 89 0.026
nucleotide catabolic process GO:0009166 109 0.026
Yeast
ubiquitin dependent protein catabolic process GO:0006511 78 0.025
Yeast
head development GO:0060322 135 0.025
Human
regulation of lipid storage GO:0010883 22 0.025
anterior posterior axis specification GO:0009948 109 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
response to monosaccharide GO:0034284 4 0.025
nitrogen compound transport GO:0071705 85 0.025
spermatid development GO:0007286 98 0.025
positive regulation of biosynthetic process GO:0009891 316 0.024
steroid biosynthetic process GO:0006694 16 0.024
regulation of notch signaling pathway GO:0008593 100 0.023
torso signaling pathway GO:0008293 21 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
response to bacterium GO:0009617 198 0.023
tube morphogenesis GO:0035239 191 0.023
regulation of tube architecture open tracheal system GO:0035152 68 0.023
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
glial cell proliferation GO:0014009 13 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
translation GO:0006412 69 0.022
regulation of protein transport GO:0051223 57 0.022
adult locomotory behavior GO:0008344 76 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
intracellular protein transport GO:0006886 104 0.022
Yeast
organic acid metabolic process GO:0006082 103 0.021
protein maturation GO:0051604 71 0.021
negative regulation of gene expression GO:0010629 387 0.021
response to lipid GO:0033993 38 0.021
protein modification process GO:0036211 438 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
cell proliferation GO:0008283 299 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
ion transport GO:0006811 145 0.021
response to other organism GO:0051707 293 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.021
Yeast
positive regulation of developmental process GO:0051094 143 0.021
positive regulation of apoptotic signaling pathway GO:2001235 4 0.021
nucleoside triphosphate catabolic process GO:0009143 108 0.021
Yeast
macromolecular complex assembly GO:0065003 256 0.020
positive regulation of signaling GO:0023056 243 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
chemical homeostasis GO:0048878 92 0.020
photoreceptor cell differentiation GO:0046530 170 0.020
embryonic axis specification GO:0000578 107 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
Yeast
axonogenesis GO:0007409 290 0.020
antimicrobial peptide production GO:0002775 46 0.020
mesenchymal cell differentiation GO:0048762 1 0.020
regulation of cell cycle g1 s phase transition GO:1902806 23 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
multicellular organismal reproductive behavior GO:0033057 110 0.019
organic anion transport GO:0015711 28 0.019
mesenchymal cell development GO:0014031 1 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
Human
oxoacid metabolic process GO:0043436 103 0.019
regulation of execution phase of apoptosis GO:1900117 5 0.019
cell cycle phase transition GO:0044770 140 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.018
response to biotic stimulus GO:0009607 294 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
nuclear transport GO:0051169 72 0.018
determination of adult lifespan GO:0008340 137 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.018
cell cycle checkpoint GO:0000075 95 0.018
peripheral nervous system development GO:0007422 52 0.018
actin filament based process GO:0030029 220 0.018
l glutamate import GO:0051938 1 0.018
actin filament based movement GO:0030048 26 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
neuron maturation GO:0042551 31 0.018
negative regulation of notch signaling pathway GO:0045746 41 0.017
apoptotic process GO:0006915 159 0.017
Human
modification dependent protein catabolic process GO:0019941 78 0.017
Yeast
transmembrane transport GO:0055085 139 0.017
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
cilium morphogenesis GO:0060271 39 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
lipid storage GO:0019915 38 0.017
protein ubiquitination GO:0016567 70 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.016
regulation of secretion GO:0051046 44 0.016
response to inorganic substance GO:0010035 44 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
multicellular organismal aging GO:0010259 140 0.016
regulation of cell proliferation GO:0042127 163 0.016
response to organic substance GO:0010033 284 0.016
Yeast
negative regulation of mitotic cell cycle GO:0045930 109 0.015
regulation of cytoplasmic transport GO:1903649 47 0.015
homeostatic process GO:0042592 199 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
response to abiotic stimulus GO:0009628 341 0.015
outflow tract morphogenesis GO:0003151 4 0.015
metal ion homeostasis GO:0055065 44 0.015
dorsal ventral axis specification GO:0009950 66 0.015
regulation of anatomical structure size GO:0090066 163 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
cellular response to nutrient levels GO:0031669 62 0.015
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.015
female sex differentiation GO:0046660 20 0.015
heterocycle catabolic process GO:0046700 166 0.015
Yeast
response to hypoxia GO:0001666 53 0.015
golgi organization GO:0007030 66 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
carboxylic acid transport GO:0046942 18 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
Yeast
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
olfactory behavior GO:0042048 97 0.014
regulation of peptidase activity GO:0052547 39 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
maintenance of location in cell GO:0051651 28 0.014
Human
regulation of production of molecular mediator of immune response GO:0002700 44 0.014
camera type eye development GO:0043010 4 0.014
regulation of apoptotic process GO:0042981 130 0.014
Human
proteasomal protein catabolic process GO:0010498 59 0.014
Yeast
segmentation GO:0035282 207 0.014
maintenance of protein location in cell GO:0032507 26 0.014
Human
organelle membrane fusion GO:0090174 16 0.014
intracellular protein transmembrane transport GO:0065002 4 0.014
Yeast
axon regeneration GO:0031103 8 0.014
male courtship behavior GO:0008049 63 0.014
negative regulation of cell cycle GO:0045786 116 0.014
dorsal closure GO:0007391 79 0.014
regulation of neuron differentiation GO:0045664 103 0.014
single organism catabolic process GO:0044712 228 0.013
Yeast
cellular hormone metabolic process GO:0034754 23 0.013
regulation of proteolysis GO:0030162 87 0.013
amine metabolic process GO:0009308 12 0.013
response to hexose GO:0009746 3 0.013
apoptotic process involved in morphogenesis GO:0060561 3 0.013
positive regulation of cell cycle GO:0045787 43 0.013
maintenance of location GO:0051235 73 0.013
Human
regulation of cellular amine metabolic process GO:0033238 3 0.013
spindle organization GO:0007051 253 0.013
ventral cord development GO:0007419 16 0.013
intracellular mrna localization GO:0008298 66 0.013
eye pigmentation GO:0048069 43 0.013
centrosome duplication GO:0051298 121 0.013
regulation of catabolic process GO:0009894 170 0.013
spinal cord development GO:0021510 1 0.013
camera type eye morphogenesis GO:0048593 2 0.013
cytokinesis GO:0000910 90 0.013
male mating behavior GO:0060179 70 0.013
endomembrane system organization GO:0010256 119 0.013
cellular response to extracellular stimulus GO:0031668 64 0.013
Human
g1 s transition of mitotic cell cycle GO:0000082 31 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
cellular response to organic substance GO:0071310 132 0.012
regulation of chitin based cuticle tanning GO:0007564 14 0.012
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
regulation of growth GO:0040008 233 0.012
mitochondrion organization GO:0007005 65 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
limb development GO:0060173 1 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
response to lipopolysaccharide GO:0032496 4 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
cellular protein catabolic process GO:0044257 83 0.012
Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of programmed cell death GO:0043067 152 0.012
Human
cellular ion homeostasis GO:0006873 39 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
Yeast
regulation of protein catabolic process GO:0042176 55 0.012
axon development GO:0061564 297 0.012
neuron projection guidance GO:0097485 241 0.012
nephron epithelium morphogenesis GO:0072088 3 0.011
imaginal disc eversion GO:0007561 4 0.011
anterior posterior pattern specification GO:0009952 136 0.011
positive regulation of retinal cell programmed cell death GO:0046670 9 0.011
mitotic dna damage checkpoint GO:0044773 74 0.011
reproductive behavior GO:0019098 122 0.011
regulation of lipid transport GO:0032368 3 0.011
rna interference GO:0016246 27 0.011
nucleoside catabolic process GO:0009164 112 0.011
Yeast
wing disc morphogenesis GO:0007472 344 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
positive regulation of peptidase activity GO:0010952 29 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
pigmentation GO:0043473 75 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
Yeast
response to decreased oxygen levels GO:0036293 58 0.011
cellular response to sterol depletion GO:0071501 3 0.011
cell adhesion GO:0007155 136 0.011
respiratory system development GO:0060541 213 0.011
golgi vesicle transport GO:0048193 27 0.011
instar larval development GO:0002168 55 0.011
mitotic spindle organization GO:0007052 220 0.011
positive regulation of immune system process GO:0002684 68 0.011
positive regulation of transport GO:0051050 92 0.011
response to alcohol GO:0097305 95 0.011
antennal morphogenesis GO:0048800 14 0.011
pigment metabolic process GO:0042440 84 0.011
apoptotic process involved in development GO:1902742 20 0.011
retina development in camera type eye GO:0060041 4 0.011
negative regulation of decapentaplegic signaling pathway GO:0090099 4 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
Yeast
regulation of catalytic activity GO:0050790 185 0.010
Yeast
cellular ketone metabolic process GO:0042180 24 0.010
chemosensory behavior GO:0007635 106 0.010
inter male aggressive behavior GO:0002121 60 0.010
chromatin organization GO:0006325 207 0.010
polyol biosynthetic process GO:0046173 3 0.010
negative regulation of transcription regulatory region dna binding GO:2000678 3 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
Yeast
retrograde transport endosome to golgi GO:0042147 3 0.010
positive regulation of neuron apoptotic process GO:0043525 1 0.010

Hsc70-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.014
disease of anatomical entity DOID:7 0 0.014
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.010
auditory system disease DOID:2742 0 0.010
nervous system disease DOID:863 0 0.010