Drosophila melanogaster

0 known processes

MED15 (Dmel_CG4184)

Mediator complex subunit 15

(Aliases: med15,BcDNA:GH03922,Arc105,dARC105,Med15,Dmel\CG4184,CG4184,Med9/ARC105)

MED15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.998
positive regulation of gene expression GO:0010628 290 0.988
positive regulation of rna metabolic process GO:0051254 271 0.973
transcription from rna polymerase ii promoter GO:0006366 368 0.970
positive regulation of cellular biosynthetic process GO:0031328 316 0.968
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.929
positive regulation of biosynthetic process GO:0009891 316 0.905
positive regulation of macromolecule metabolic process GO:0010604 405 0.873
positive regulation of rna biosynthetic process GO:1902680 266 0.845
positive regulation of transcription dna templated GO:0045893 266 0.800
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.754
positive regulation of nucleic acid templated transcription GO:1903508 266 0.713
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.629
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.518
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.518
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.499
negative regulation of gene expression GO:0010629 387 0.479
localization of cell GO:0051674 257 0.477
protein modification process GO:0036211 438 0.441
negative regulation of cellular biosynthetic process GO:0031327 277 0.434
embryo development ending in birth or egg hatching GO:0009792 152 0.424
negative regulation of rna metabolic process GO:0051253 251 0.369
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.365
negative regulation of biosynthetic process GO:0009890 277 0.334
regulation of cell cycle process GO:0010564 181 0.330
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.326
negative regulation of cell cycle GO:0045786 116 0.324
cellular macromolecule catabolic process GO:0044265 136 0.295
negative regulation of rna biosynthetic process GO:1902679 240 0.283
regulation of cell cycle GO:0051726 291 0.281
embryonic morphogenesis GO:0048598 206 0.278
negative regulation of cell proliferation GO:0008285 69 0.273
posttranscriptional gene silencing by rna GO:0035194 45 0.230
imaginal disc derived appendage development GO:0048737 399 0.224
positive regulation of signaling GO:0023056 243 0.222
antimicrobial humoral response GO:0019730 99 0.211
muscle structure development GO:0061061 224 0.204
protein complex assembly GO:0006461 200 0.200
macromolecule catabolic process GO:0009057 161 0.198
larval development GO:0002164 104 0.197
regionalization GO:0003002 416 0.193
chromatin modification GO:0016568 147 0.192
negative regulation of cell cycle process GO:0010948 109 0.190
organic substance catabolic process GO:1901575 308 0.182
regulation of programmed cell death GO:0043067 152 0.180
regulation of catabolic process GO:0009894 170 0.178
negative regulation of transcription dna templated GO:0045892 237 0.173
regulation of response to external stimulus GO:0032101 115 0.168
regulation of cellular protein metabolic process GO:0032268 243 0.164
regulation of nervous system development GO:0051960 248 0.158
meiotic cell cycle GO:0051321 171 0.155
response to other organism GO:0051707 293 0.154
cell migration GO:0016477 238 0.151
appendage development GO:0048736 401 0.150
negative regulation of cellular metabolic process GO:0031324 382 0.149
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.149
phosphorylation GO:0016310 294 0.147
regulation of cell proliferation GO:0042127 163 0.144
vesicle mediated transport GO:0016192 381 0.136
regulation of mitotic cell cycle GO:0007346 190 0.136
negative regulation of response to stimulus GO:0048585 258 0.136
cellular catabolic process GO:0044248 372 0.136
negative regulation of nucleic acid templated transcription GO:1903507 240 0.135
cell motility GO:0048870 251 0.130
positive regulation of cell communication GO:0010647 250 0.127
cell death GO:0008219 279 0.126
positive regulation of mrna metabolic process GO:1903313 5 0.121
catabolic process GO:0009056 409 0.120
gene silencing by rna GO:0031047 57 0.117
regulation of cell differentiation GO:0045595 302 0.115
chromatin organization GO:0006325 207 0.115
regulation of multi organism process GO:0043900 131 0.114
mitotic spindle organization GO:0007052 220 0.110
response to biotic stimulus GO:0009607 294 0.108
organelle fission GO:0048285 340 0.108
mitotic cell cycle phase transition GO:0044772 138 0.107
forebrain development GO:0030900 2 0.107
negative regulation of mitotic cell cycle GO:0045930 109 0.105
posttranscriptional regulation of gene expression GO:0010608 145 0.103
regulation of dna recombination GO:0000018 4 0.103
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.102
positive regulation of signal transduction GO:0009967 223 0.102
protein complex disassembly GO:0043241 36 0.102
histone h3 k4 methylation GO:0051568 16 0.101
response to external biotic stimulus GO:0043207 293 0.100
cell proliferation GO:0008283 299 0.098
enzyme linked receptor protein signaling pathway GO:0007167 179 0.097
nuclear division GO:0000280 332 0.096
cellular protein modification process GO:0006464 438 0.092
regulation of neurogenesis GO:0050767 158 0.092
protein phosphorylation GO:0006468 169 0.089
macromolecular complex assembly GO:0065003 256 0.089
protein complex biogenesis GO:0070271 201 0.088
body morphogenesis GO:0010171 2 0.088
regulation of immune response GO:0050776 118 0.086
death GO:0016265 284 0.083
immune system process GO:0002376 347 0.083
immune response GO:0006955 246 0.080
ameboidal type cell migration GO:0001667 151 0.080
ubiquitin dependent protein catabolic process GO:0006511 78 0.079
production of molecular mediator of immune response GO:0002440 46 0.079
regulation of multicellular organismal development GO:2000026 414 0.078
response to abiotic stimulus GO:0009628 341 0.077
endocytosis GO:0006897 310 0.076
negative regulation of apoptotic process GO:0043066 63 0.070
dna damage checkpoint GO:0000077 78 0.069
posttranscriptional gene silencing GO:0016441 46 0.069
regulation of protein modification process GO:0031399 112 0.069
stem cell differentiation GO:0048863 117 0.068
modification dependent protein catabolic process GO:0019941 78 0.067
single organism intracellular transport GO:1902582 207 0.066
protein catabolic process GO:0030163 101 0.064
positive regulation of response to stimulus GO:0048584 323 0.064
proteasomal protein catabolic process GO:0010498 59 0.063
regulation of immune system process GO:0002682 176 0.063
negative regulation of developmental process GO:0051093 201 0.063
head development GO:0060322 135 0.061
intracellular transport GO:0046907 228 0.061
negative regulation of multicellular organismal process GO:0051241 142 0.061
response to organic substance GO:0010033 284 0.060
regulation of secretion by cell GO:1903530 39 0.059
regulation of cellular localization GO:0060341 136 0.058
cell cycle checkpoint GO:0000075 95 0.057
regulation of cell cycle phase transition GO:1901987 130 0.055
proteolysis GO:0006508 192 0.054
camera type eye development GO:0043010 4 0.054
tissue morphogenesis GO:0048729 297 0.053
wnt signaling pathway GO:0016055 98 0.053
gene silencing GO:0016458 138 0.052
imaginal disc derived appendage morphogenesis GO:0035114 395 0.049
programmed cell death GO:0012501 257 0.048
apoptotic process GO:0006915 159 0.047
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.047
cell type specific apoptotic process GO:0097285 38 0.046
modification dependent macromolecule catabolic process GO:0043632 79 0.045
regulation of phosphorus metabolic process GO:0051174 210 0.044
response to radiation GO:0009314 155 0.043
oxoacid metabolic process GO:0043436 103 0.043
anterior posterior pattern specification GO:0009952 136 0.043
histone lysine demethylation GO:0070076 6 0.043
cell fate specification GO:0001708 71 0.043
establishment of localization in cell GO:0051649 402 0.043
positive regulation of cellular component organization GO:0051130 156 0.042
regulation of humoral immune response GO:0002920 51 0.040
regulation of cell projection organization GO:0031344 92 0.040
mitotic g2 dna damage checkpoint GO:0007095 69 0.040
spindle organization GO:0007051 253 0.039
erbb signaling pathway GO:0038127 58 0.039
regulation of erbb signaling pathway GO:1901184 42 0.039
regulation of response to stress GO:0080134 200 0.039
regulation of response to biotic stimulus GO:0002831 63 0.038
embryonic development via the syncytial blastoderm GO:0001700 148 0.037
positive regulation of catabolic process GO:0009896 105 0.037
notch signaling pathway GO:0007219 120 0.036
small molecule metabolic process GO:0044281 305 0.036
protein localization GO:0008104 284 0.036
regulation of defense response GO:0031347 102 0.035
negative regulation of cell cycle phase transition GO:1901988 103 0.035
organonitrogen compound metabolic process GO:1901564 318 0.035
negative regulation of signaling GO:0023057 219 0.034
positive regulation of immune response GO:0050778 63 0.034
protein acylation GO:0043543 42 0.034
regulation of phosphorylation GO:0042325 147 0.034
rna 3 end processing GO:0031123 45 0.033
negative regulation of programmed cell death GO:0043069 72 0.033
regulation of notch signaling pathway GO:0008593 100 0.033
cellular amino acid metabolic process GO:0006520 61 0.032
intracellular signal transduction GO:0035556 300 0.031
organonitrogen compound biosynthetic process GO:1901566 117 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.031
secondary metabolic process GO:0019748 75 0.031
regulation of cellular catabolic process GO:0031329 157 0.031
regulation of localization GO:0032879 275 0.031
secretion by cell GO:0032940 101 0.030
carboxylic acid metabolic process GO:0019752 92 0.030
cellular component disassembly GO:0022411 46 0.030
imaginal disc derived leg morphogenesis GO:0007480 80 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
mrna 3 end processing GO:0031124 28 0.029
phagocytosis GO:0006909 215 0.029
mitotic g2 m transition checkpoint GO:0044818 70 0.029
cell cycle phase transition GO:0044770 140 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.028
negative regulation of cell differentiation GO:0045596 143 0.028
imaginal disc derived leg segmentation GO:0036011 26 0.028
cellular protein catabolic process GO:0044257 83 0.028
regulation of protein metabolic process GO:0051246 256 0.028
development of primary sexual characteristics GO:0045137 50 0.028
antimicrobial peptide production GO:0002775 46 0.028
positive regulation of developmental process GO:0051094 143 0.027
wing disc morphogenesis GO:0007472 344 0.027
growth GO:0040007 359 0.027
protein modification by small protein removal GO:0070646 28 0.027
regulation of protein catabolic process GO:0042176 55 0.027
regulation of cell development GO:0060284 215 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
epithelial cell development GO:0002064 274 0.027
inositol lipid mediated signaling GO:0048017 4 0.026
protein modification by small protein conjugation GO:0032446 79 0.026
translation GO:0006412 69 0.026
regulation of secretion GO:0051046 44 0.026
protein import into nucleus GO:0006606 51 0.025
regulation of production of molecular mediator of immune response GO:0002700 44 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
reproductive system development GO:0061458 74 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.025
regulation of protein phosphorylation GO:0001932 64 0.025
signal transduction by phosphorylation GO:0023014 107 0.024
rna interference GO:0016246 27 0.024
chemotaxis GO:0006935 249 0.024
cytoplasmic transport GO:0016482 130 0.024
cellular protein localization GO:0034613 160 0.024
regulation of antimicrobial humoral response GO:0002759 50 0.023
regulation of locomotion GO:0040012 42 0.023
mitotic nuclear division GO:0007067 213 0.023
chromatin assembly or disassembly GO:0006333 52 0.023
cellular response to chemical stimulus GO:0070887 199 0.022
positive regulation of multi organism process GO:0043902 40 0.022
immune effector process GO:0002252 98 0.022
regulation of cellular component movement GO:0051270 42 0.021
regulation of antimicrobial peptide production GO:0002784 44 0.021
sex differentiation GO:0007548 81 0.021
signal release GO:0023061 49 0.021
gonad development GO:0008406 50 0.021
amine metabolic process GO:0009308 12 0.021
cellular macromolecular complex assembly GO:0034622 153 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
tube development GO:0035295 244 0.021
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.020
mitotic dna damage checkpoint GO:0044773 74 0.020
mitotic dna integrity checkpoint GO:0044774 75 0.020
apoptotic cell clearance GO:0043277 14 0.020
regulation of immune effector process GO:0002697 52 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
synaptic transmission GO:0007268 288 0.020
macromolecular complex disassembly GO:0032984 37 0.020
intracellular protein transport GO:0006886 104 0.020
centrosome organization GO:0051297 163 0.020
organic acid metabolic process GO:0006082 103 0.019
cellular ketone metabolic process GO:0042180 24 0.019
chaeta development GO:0022416 97 0.019
mrna processing GO:0006397 104 0.019
g2 dna damage checkpoint GO:0031572 69 0.018
establishment of protein localization GO:0045184 163 0.018
regulation of molecular function GO:0065009 217 0.018
cell division GO:0051301 248 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
convergent extension GO:0060026 2 0.018
endomembrane system organization GO:0010256 119 0.018
positive regulation of secretion by cell GO:1903532 20 0.018
regulation of transport GO:0051049 181 0.018
membrane organization GO:0061024 112 0.018
single organism cellular localization GO:1902580 180 0.018
protein transport GO:0015031 155 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
innate immune response GO:0045087 144 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
response to extracellular stimulus GO:0009991 116 0.017
negative regulation of stem cell proliferation GO:2000647 30 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
response to light stimulus GO:0009416 124 0.016
neuron projection guidance GO:0097485 241 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
protein maturation GO:0051604 71 0.016
regulation of apoptotic process GO:0042981 130 0.016
asymmetric cell division GO:0008356 37 0.016
spermatid differentiation GO:0048515 114 0.016
response to wounding GO:0009611 94 0.016
response to oxygen containing compound GO:1901700 200 0.016
covalent chromatin modification GO:0016569 106 0.015
histone modification GO:0016570 106 0.015
positive regulation of transport GO:0051050 92 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
positive regulation of mrna processing GO:0050685 4 0.015
cell cycle arrest GO:0007050 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
response to organic cyclic compound GO:0014070 89 0.015
regulation of cell motility GO:2000145 23 0.015
centrosome duplication GO:0051298 121 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
positive regulation of molecular function GO:0044093 136 0.014
glial cell differentiation GO:0010001 35 0.014
peptide biosynthetic process GO:0043043 42 0.014
organic substance transport GO:0071702 257 0.014
negative regulation of signal transduction GO:0009968 206 0.014
regulation of cell death GO:0010941 173 0.014
regulation of mapk cascade GO:0043408 92 0.014
gland morphogenesis GO:0022612 145 0.014
multicellular organismal homeostasis GO:0048871 41 0.014
negative regulation of cell communication GO:0010648 223 0.014
positive regulation of cell differentiation GO:0045597 64 0.013
neural precursor cell proliferation GO:0061351 75 0.013
response to nutrient levels GO:0031667 114 0.013
secretion GO:0046903 109 0.013
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.013
salivary gland morphogenesis GO:0007435 145 0.013
dna integrity checkpoint GO:0031570 81 0.013
defense response to other organism GO:0098542 225 0.013
regulation of protein localization GO:0032880 76 0.013
regulation of mrna 3 end processing GO:0031440 7 0.013
centrosome cycle GO:0007098 137 0.012
organelle assembly GO:0070925 198 0.012
histone lysine methylation GO:0034968 32 0.012
appendage morphogenesis GO:0035107 397 0.012
negative regulation of cell death GO:0060548 81 0.012
rna processing GO:0006396 147 0.012
regulation of transferase activity GO:0051338 58 0.012
dorsal ventral axis specification GO:0009950 66 0.012
chromosome organization GO:0051276 360 0.012
regulation of kinase activity GO:0043549 53 0.011
cellular protein complex assembly GO:0043623 71 0.011
aromatic compound catabolic process GO:0019439 166 0.011
head involution GO:0008258 35 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
central nervous system development GO:0007417 201 0.011
axon development GO:0061564 297 0.011
gland development GO:0048732 191 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
connective tissue development GO:0061448 3 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
microtubule organizing center organization GO:0031023 168 0.011
spinal cord development GO:0021510 1 0.011
chromosome segregation GO:0007059 157 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
positive regulation of cell migration GO:0030335 2 0.011
response to dsrna GO:0043331 15 0.011
regulation of proteasomal protein catabolic process GO:0061136 39 0.011
nuclear import GO:0051170 51 0.011
methylation GO:0032259 47 0.011
axis specification GO:0009798 167 0.010
regulation of cell migration GO:0030334 22 0.010
protein ubiquitination GO:0016567 70 0.010
spermatid development GO:0007286 98 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
dorsal closure GO:0007391 79 0.010

MED15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019