Drosophila melanogaster

56 known processes

Got2 (Dmel_CG4233)

Glutamate oxaloacetate transaminase 2

(Aliases: 152801_at,CG4233,got2,Got,Got-2,Dmel\CG4233)

Got2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nicotinamide nucleotide metabolic process GO:0046496 2 0.767
small molecule metabolic process GO:0044281 305 0.708
pyridine containing compound metabolic process GO:0072524 3 0.687
oxidation reduction process GO:0055114 123 0.534
pyridine nucleotide metabolic process GO:0019362 2 0.521
organonitrogen compound biosynthetic process GO:1901566 117 0.424
carboxylic acid metabolic process GO:0019752 92 0.396
response to organic cyclic compound GO:0014070 89 0.390
monocarboxylic acid metabolic process GO:0032787 29 0.366
pyruvate metabolic process GO:0006090 7 0.359
oxidoreduction coenzyme metabolic process GO:0006733 2 0.326
organonitrogen compound metabolic process GO:1901564 318 0.260
single organism carbohydrate metabolic process GO:0044723 72 0.247
organic acid metabolic process GO:0006082 103 0.241
oxoacid metabolic process GO:0043436 103 0.218
nucleobase containing small molecule metabolic process GO:0055086 174 0.210
cellular polysaccharide metabolic process GO:0044264 11 0.202
carbohydrate metabolic process GO:0005975 82 0.201
negative regulation of biosynthetic process GO:0009890 277 0.200
nucleotide metabolic process GO:0009117 161 0.188
single organism biosynthetic process GO:0044711 206 0.174
organophosphate metabolic process GO:0019637 195 0.172
catabolic process GO:0009056 409 0.166
Human Mouse
response to extracellular stimulus GO:0009991 116 0.138
carbohydrate biosynthetic process GO:0016051 17 0.122
acetaldehyde metabolic process GO:0006117 5 0.112
single organism catabolic process GO:0044712 228 0.106
Human Mouse
nucleoside phosphate metabolic process GO:0006753 162 0.105
organic substance catabolic process GO:1901575 308 0.101
Human Mouse
carboxylic acid biosynthetic process GO:0046394 15 0.100
negative regulation of gene expression GO:0010629 387 0.099
response to nutrient levels GO:0031667 114 0.093
glutamate metabolic process GO:0006536 5 0.088
monocarboxylic acid biosynthetic process GO:0072330 7 0.078
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.076
cellular amino acid biosynthetic process GO:0008652 9 0.075
response to endogenous stimulus GO:0009719 119 0.074
negative regulation of cellular biosynthetic process GO:0031327 277 0.069
response to organic substance GO:0010033 284 0.067
Human
cellular aldehyde metabolic process GO:0006081 10 0.067
small molecule catabolic process GO:0044282 21 0.066
Human Mouse
response to oxygen containing compound GO:1901700 200 0.065
Human
response to metal ion GO:0010038 23 0.063
single organism carbohydrate catabolic process GO:0044724 7 0.061
cellular ketone metabolic process GO:0042180 24 0.060
cellular amino acid metabolic process GO:0006520 61 0.060
sulfur compound metabolic process GO:0006790 59 0.057
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.056
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.056
hexose metabolic process GO:0019318 8 0.050
polysaccharide biosynthetic process GO:0000271 7 0.050
cellular lipid metabolic process GO:0044255 83 0.050
negative regulation of cellular metabolic process GO:0031324 382 0.050
regulation of cellular ketone metabolic process GO:0010565 3 0.049
alpha amino acid metabolic process GO:1901605 20 0.048
regulation of cellular protein metabolic process GO:0032268 243 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.048
pentose metabolic process GO:0019321 1 0.046
lipid metabolic process GO:0006629 121 0.046
amine metabolic process GO:0009308 12 0.045
carbohydrate catabolic process GO:0016052 7 0.044
mushroom body development GO:0016319 70 0.044
response to organophosphorus GO:0046683 2 0.043
negative regulation of rna metabolic process GO:0051253 251 0.042
cellular amine metabolic process GO:0044106 12 0.040
macromolecular complex assembly GO:0065003 256 0.039
response to monosaccharide GO:0034284 4 0.039
head development GO:0060322 135 0.039
fatty acid metabolic process GO:0006631 20 0.038
acyl coa metabolic process GO:0006637 3 0.038
single organism behavior GO:0044708 391 0.038
telencephalon development GO:0021537 2 0.037
protein complex assembly GO:0006461 200 0.037
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
nucleoside metabolic process GO:0009116 127 0.034
development of primary female sexual characteristics GO:0046545 12 0.034
organic hydroxy compound metabolic process GO:1901615 83 0.033
cellular lipid catabolic process GO:0044242 16 0.033
regulation of rna splicing GO:0043484 69 0.033
organophosphate biosynthetic process GO:0090407 46 0.033
cofactor metabolic process GO:0051186 13 0.032
cellular polysaccharide biosynthetic process GO:0033692 7 0.032
female gonad development GO:0008585 12 0.032
response to ethanol GO:0045471 59 0.032
Human
negative regulation of nucleic acid templated transcription GO:1903507 240 0.031
glucose metabolic process GO:0006006 5 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
forebrain development GO:0030900 2 0.031
carbohydrate derivative biosynthetic process GO:1901137 85 0.031
lipid catabolic process GO:0016042 21 0.031
cellular response to chemical stimulus GO:0070887 199 0.030
response to abiotic stimulus GO:0009628 341 0.030
behavioral response to ethanol GO:0048149 49 0.030
rna processing GO:0006396 147 0.029
homeostatic process GO:0042592 199 0.029
tricarboxylic acid metabolic process GO:0072350 1 0.027
spermatogenesis GO:0007283 200 0.027
positive regulation of signaling GO:0023056 243 0.027
cellular response to organic substance GO:0071310 132 0.027
monosaccharide metabolic process GO:0005996 9 0.027
positive regulation of response to stimulus GO:0048584 323 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.025
cellular catabolic process GO:0044248 372 0.025
Human Mouse
organonitrogen compound catabolic process GO:1901565 128 0.025
Human Mouse
polysaccharide metabolic process GO:0005976 11 0.025
steroid catabolic process GO:0006706 1 0.025
response to hexose GO:0009746 3 0.025
establishment of localization in cell GO:0051649 402 0.025
appendage development GO:0048736 401 0.024
endocytosis GO:0006897 310 0.024
ribose phosphate biosynthetic process GO:0046390 28 0.024
protein complex biogenesis GO:0070271 201 0.024
response to glucose GO:0009749 2 0.024
female sex differentiation GO:0046660 20 0.023
protein targeting to nucleus GO:0044744 51 0.023
cellular biogenic amine catabolic process GO:0042402 1 0.023
alpha amino acid biosynthetic process GO:1901607 4 0.022
organelle assembly GO:0070925 198 0.022
proteolysis GO:0006508 192 0.021
generation of precursor metabolites and energy GO:0006091 42 0.021
regulation of apoptotic process GO:0042981 130 0.021
central nervous system development GO:0007417 201 0.021
regulation of catalytic activity GO:0050790 185 0.021
cell type specific apoptotic process GO:0097285 38 0.021
cell proliferation GO:0008283 299 0.021
nephron epithelium development GO:0072009 3 0.021
small molecule biosynthetic process GO:0044283 37 0.020
regulation of localization GO:0032879 275 0.020
wing disc morphogenesis GO:0007472 344 0.019
appendage morphogenesis GO:0035107 397 0.019
syncytium formation GO:0006949 43 0.019
regulation of programmed cell death GO:0043067 152 0.019
striated muscle myosin thick filament assembly GO:0071688 3 0.019
nucleoside phosphate biosynthetic process GO:1901293 34 0.019
vesicle mediated transport GO:0016192 381 0.019
purine nucleotide biosynthetic process GO:0006164 29 0.019
neurological system process GO:0050877 358 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
maintenance of location GO:0051235 73 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
response to lipid GO:0033993 38 0.018
ribonucleoside biosynthetic process GO:0042455 3 0.018
regulation of protein metabolic process GO:0051246 256 0.017
sex differentiation GO:0007548 81 0.017
lipid oxidation GO:0034440 7 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
body morphogenesis GO:0010171 2 0.017
primary alcohol metabolic process GO:0034308 2 0.017
positive regulation of cell communication GO:0010647 250 0.016
nad metabolic process GO:0019674 1 0.016
programmed cell death GO:0012501 257 0.016
cellular modified amino acid metabolic process GO:0006575 45 0.016
response to starvation GO:0042594 97 0.016
glucan biosynthetic process GO:0009250 2 0.016
response to wounding GO:0009611 94 0.016
cognition GO:0050890 141 0.015
response to temperature stimulus GO:0009266 106 0.015
associative learning GO:0008306 65 0.015
positive regulation of cell death GO:0010942 69 0.015
lipid modification GO:0030258 24 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
positive regulation of molecular function GO:0044093 136 0.015
death GO:0016265 284 0.015
purine containing compound metabolic process GO:0072521 155 0.015
amine catabolic process GO:0009310 1 0.014
organic acid biosynthetic process GO:0016053 15 0.014
regulation of molecular function GO:0065009 217 0.014
protein modification process GO:0036211 438 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
anion transport GO:0006820 41 0.014
Human
immune system process GO:0002376 347 0.014
lateral inhibition GO:0046331 206 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
regulation of proteolysis GO:0030162 87 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
positive regulation of signal transduction GO:0009967 223 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
gene silencing GO:0016458 138 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
androgen metabolic process GO:0008209 1 0.013
protein localization GO:0008104 284 0.013
phagocytosis GO:0006909 215 0.013
epithelial cell differentiation GO:0030855 322 0.013
organic hydroxy compound catabolic process GO:1901616 4 0.013
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
cellular protein modification process GO:0006464 438 0.012
thioester biosynthetic process GO:0035384 2 0.012
mrna processing GO:0006397 104 0.012
response to calcium ion GO:0051592 1 0.012
cellular response to starvation GO:0009267 61 0.012
negative regulation of signaling GO:0023057 219 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
kidney development GO:0001822 3 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
transmembrane transport GO:0055085 139 0.011
chromatin modification GO:0016568 147 0.011
organic acid catabolic process GO:0016054 16 0.011
Human Mouse
regulation of transport GO:0051049 181 0.011
ion transport GO:0006811 145 0.011
Human
glycerolipid catabolic process GO:0046503 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
response to carbohydrate GO:0009743 15 0.011
cellular carbohydrate biosynthetic process GO:0034637 7 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
single organism cellular localization GO:1902580 180 0.010
nucleotide biosynthetic process GO:0009165 34 0.010
rna splicing GO:0008380 83 0.010
spindle organization GO:0007051 253 0.010
lipid localization GO:0010876 54 0.010
Human
wound healing GO:0042060 75 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
negative regulation of gene expression epigenetic GO:0045814 77 0.010
response to organonitrogen compound GO:0010243 75 0.010
purine nucleoside biosynthetic process GO:0042451 3 0.010
connective tissue development GO:0061448 3 0.010
adult behavior GO:0030534 137 0.010

Got2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.381
inherited metabolic disorder DOID:655 0 0.381
carbohydrate metabolism disease DOID:0050013 0 0.111
glucose metabolism disease DOID:4194 0 0.111
acquired metabolic disease DOID:0060158 0 0.111
disease of anatomical entity DOID:7 0 0.031