Drosophila melanogaster

40 known processes

c(2)M (Dmel_CG4249)

crossover suppressor on 2 of Manheim

(Aliases: c(2)m,C(2)M,Dmel\CG4249,BG:DS02740.10,DS02740.10,mei-910,MEI-910,CG4249)

c(2)M biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 332 0.140
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.106
negative regulation of cellular metabolic process GO:0031324 382 0.093
meiotic nuclear division GO:0007126 151 0.092
meiotic cell cycle GO:0051321 171 0.091
cellular catabolic process GO:0044248 372 0.090
organelle fission GO:0048285 340 0.087
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.084
catabolic process GO:0009056 409 0.079
cellular component assembly involved in morphogenesis GO:0010927 151 0.070
meiotic cell cycle process GO:1903046 132 0.066
positive regulation of nucleic acid templated transcription GO:1903508 266 0.060
epithelial cell differentiation GO:0030855 322 0.055
morphogenesis of an epithelium GO:0002009 276 0.055
organic substance catabolic process GO:1901575 308 0.053
heterocycle catabolic process GO:0046700 166 0.053
regulation of response to stress GO:0080134 200 0.053
salivary gland morphogenesis GO:0007435 145 0.051
positive regulation of biosynthetic process GO:0009891 316 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
chromosome separation GO:0051304 42 0.048
tissue morphogenesis GO:0048729 297 0.047
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.046
columnar cuboidal epithelial cell development GO:0002066 249 0.045
positive regulation of rna metabolic process GO:0051254 271 0.045
ovarian follicle cell development GO:0030707 248 0.043
small molecule metabolic process GO:0044281 305 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
organonitrogen compound metabolic process GO:1901564 318 0.041
gland morphogenesis GO:0022612 145 0.041
aromatic compound catabolic process GO:0019439 166 0.039
epithelial cell development GO:0002064 274 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.038
negative regulation of gene expression GO:0010629 387 0.038
gland development GO:0048732 191 0.037
reciprocal meiotic recombination GO:0007131 19 0.037
macromolecule catabolic process GO:0009057 161 0.037
male meiosis GO:0007140 52 0.037
meiosis i GO:0007127 59 0.037
nucleobase containing compound catabolic process GO:0034655 165 0.037
positive regulation of gene expression GO:0010628 290 0.036
single organism catabolic process GO:0044712 228 0.036
salivary gland development GO:0007431 162 0.035
regionalization GO:0003002 416 0.035
response to abiotic stimulus GO:0009628 341 0.035
protein localization GO:0008104 284 0.035
associative learning GO:0008306 65 0.034
oxoacid metabolic process GO:0043436 103 0.034
negative regulation of rna biosynthetic process GO:1902679 240 0.034
chromosome organization GO:0051276 360 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
neurological system process GO:0050877 358 0.033
male gamete generation GO:0048232 201 0.033
developmental programmed cell death GO:0010623 138 0.032
regulation of multicellular organismal development GO:2000026 414 0.032
eye morphogenesis GO:0048592 260 0.032
positive regulation of transcription dna templated GO:0045893 266 0.031
female meiotic division GO:0007143 70 0.031
dna recombination GO:0006310 32 0.030
organophosphate metabolic process GO:0019637 195 0.030
spermatogenesis GO:0007283 200 0.030
negative regulation of transcription dna templated GO:0045892 237 0.029
eggshell formation GO:0030703 105 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
establishment or maintenance of cell polarity GO:0007163 167 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.028
mitotic nuclear division GO:0007067 213 0.028
axis specification GO:0009798 167 0.028
ion transmembrane transport GO:0034220 122 0.028
exocrine system development GO:0035272 162 0.028
inter male aggressive behavior GO:0002121 60 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.027
regulation of cell differentiation GO:0045595 302 0.027
meiotic chromosome segregation GO:0045132 59 0.027
sensory organ morphogenesis GO:0090596 260 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
gene silencing GO:0016458 138 0.027
eye development GO:0001654 323 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
regulation of catabolic process GO:0009894 170 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.025
macromolecular complex assembly GO:0065003 256 0.025
eggshell chorion assembly GO:0007306 66 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
chemosensory behavior GO:0007635 106 0.025
establishment of localization in cell GO:0051649 402 0.025
anterior posterior axis specification embryo GO:0008595 103 0.024
transmembrane transport GO:0055085 139 0.024
cellular macromolecule localization GO:0070727 220 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
histolysis GO:0007559 102 0.024
appendage development GO:0048736 401 0.023
nucleoside catabolic process GO:0009164 112 0.023
ribonucleoside catabolic process GO:0042454 112 0.023
intracellular transport GO:0046907 228 0.023
chromatin organization GO:0006325 207 0.023
camera type eye development GO:0043010 4 0.023
salivary gland histolysis GO:0035070 88 0.023
chromatin silencing GO:0006342 76 0.022
open tracheal system development GO:0007424 204 0.022
response to biotic stimulus GO:0009607 294 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
protein modification process GO:0036211 438 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
ion transport GO:0006811 145 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
proteolysis GO:0006508 192 0.021
response to other organism GO:0051707 293 0.021
spindle organization GO:0007051 253 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
organophosphate catabolic process GO:0046434 112 0.021
taxis GO:0042330 304 0.021
regulation of mitotic cell cycle GO:0007346 190 0.020
developmental maturation GO:0021700 172 0.020
purine containing compound catabolic process GO:0072523 112 0.020
organic acid metabolic process GO:0006082 103 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
single organism behavior GO:0044708 391 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
olfactory learning GO:0008355 56 0.020
positive regulation of signal transduction GO:0009967 223 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
chorion containing eggshell formation GO:0007304 105 0.020
locomotory behavior GO:0007626 176 0.020
dna repair GO:0006281 54 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
response to temperature stimulus GO:0009266 106 0.020
regulation of embryonic development GO:0045995 68 0.020
phagocytosis GO:0006909 215 0.020
segmentation GO:0035282 207 0.019
synaptic transmission GO:0007268 288 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
dna metabolic process GO:0006259 227 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.019
respiratory system development GO:0060541 213 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
protein catabolic process GO:0030163 101 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
cell recognition GO:0008037 102 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
endocytosis GO:0006897 310 0.018
negative regulation of cell communication GO:0010648 223 0.018
autophagic cell death GO:0048102 83 0.018
tissue death GO:0016271 102 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
immune system process GO:0002376 347 0.018
positive regulation of cell communication GO:0010647 250 0.018
negative regulation of gene expression epigenetic GO:0045814 77 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
cellular protein modification process GO:0006464 438 0.018
protein complex assembly GO:0006461 200 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
positive regulation of molecular function GO:0044093 136 0.018
purine containing compound metabolic process GO:0072521 155 0.017
nucleoside metabolic process GO:0009116 127 0.017
regulation of chromatin silencing GO:0031935 36 0.017
aggressive behavior GO:0002118 63 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
cell division GO:0051301 248 0.017
compound eye development GO:0048749 307 0.017
cell maturation GO:0048469 144 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
autophagy GO:0006914 108 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
chromosome segregation GO:0007059 157 0.017
response to external biotic stimulus GO:0043207 293 0.017
response to organic substance GO:0010033 284 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.016
organelle assembly GO:0070925 198 0.016
regulation of immune system process GO:0002682 176 0.016
egg activation GO:0007343 9 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
cellular protein complex assembly GO:0043623 71 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of anatomical structure size GO:0090066 163 0.016
organic substance transport GO:0071702 257 0.016
establishment of planar polarity GO:0001736 87 0.016
nucleotide catabolic process GO:0009166 109 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of cell cycle GO:0051726 291 0.015
dendrite development GO:0016358 204 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
dendrite morphogenesis GO:0048813 199 0.015
cellular protein catabolic process GO:0044257 83 0.015
negative regulation of developmental process GO:0051093 201 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
regulation of immune response GO:0050776 118 0.015
regulation of catalytic activity GO:0050790 185 0.015
appendage morphogenesis GO:0035107 397 0.015
embryonic pattern specification GO:0009880 174 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
regulation of cell cycle process GO:0010564 181 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
regulation of nervous system development GO:0051960 248 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
mitotic sister chromatid segregation GO:0000070 87 0.015
olfactory behavior GO:0042048 97 0.015
regulation of mrna processing GO:0050684 71 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
cellular amine metabolic process GO:0044106 12 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
maintenance of location GO:0051235 73 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
dorsal appendage formation GO:0046843 47 0.015
programmed cell death GO:0012501 257 0.015
establishment of cell polarity GO:0030010 40 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cation transport GO:0006812 110 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
compound eye photoreceptor development GO:0042051 78 0.014
regulation of protein metabolic process GO:0051246 256 0.014
spindle assembly GO:0051225 80 0.014
response to oxygen containing compound GO:1901700 200 0.014
mrna processing GO:0006397 104 0.014
single organism cellular localization GO:1902580 180 0.014
actin cytoskeleton organization GO:0030036 206 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
camera type eye morphogenesis GO:0048593 2 0.014
establishment of ommatidial planar polarity GO:0042067 49 0.014
establishment of tissue polarity GO:0007164 87 0.014
gene silencing by rna GO:0031047 57 0.014
long term memory GO:0007616 62 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
regulation of molecular function GO:0065009 217 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
single organism intracellular transport GO:1902582 207 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
compound eye morphogenesis GO:0001745 249 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
protein ubiquitination GO:0016567 70 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
cellular protein localization GO:0034613 160 0.014
regulation of multi organism process GO:0043900 131 0.014
cytoskeleton dependent cytokinesis GO:0061640 81 0.014
glycosyl compound catabolic process GO:1901658 112 0.013
regulation of cell shape GO:0008360 113 0.013
regulation of mrna metabolic process GO:1903311 72 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cell proliferation GO:0008283 299 0.013
mitotic cell cycle embryonic GO:0045448 38 0.013
protein maturation GO:0051604 71 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
establishment of organelle localization GO:0051656 122 0.013
learning GO:0007612 75 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
immune response GO:0006955 246 0.013
learning or memory GO:0007611 141 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
protein complex biogenesis GO:0070271 201 0.013
single organism biosynthetic process GO:0044711 206 0.013
response to organophosphorus GO:0046683 2 0.013
nucleotide metabolic process GO:0009117 161 0.013
regulation of organ morphogenesis GO:2000027 78 0.013
protein phosphorylation GO:0006468 169 0.013
negative regulation of cell cycle GO:0045786 116 0.013
homeostatic process GO:0042592 199 0.013
regulation of localization GO:0032879 275 0.013
sterol homeostasis GO:0055092 4 0.013
regulation of phosphorylation GO:0042325 147 0.013
vesicle mediated transport GO:0016192 381 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
mitotic spindle organization GO:0007052 220 0.013
positive regulation of catabolic process GO:0009896 105 0.013
cholesterol homeostasis GO:0042632 3 0.013
positive regulation of signaling GO:0023056 243 0.012
ribonucleoside monophosphate catabolic process GO:0009158 39 0.012
neuron recognition GO:0008038 101 0.012
protein localization to peroxisome GO:0072662 2 0.012
tripartite regional subdivision GO:0007351 103 0.012
amine metabolic process GO:0009308 12 0.012
response to lipopolysaccharide GO:0032496 4 0.012
regulation of gene silencing GO:0060968 63 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
sulfur compound metabolic process GO:0006790 59 0.012
cellular ketone metabolic process GO:0042180 24 0.012
establishment of protein localization GO:0045184 163 0.012
cognition GO:0050890 141 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
anterior posterior axis specification GO:0009948 109 0.012
mrna metabolic process GO:0016071 124 0.012
kidney development GO:0001822 3 0.012
stem cell differentiation GO:0048863 117 0.012
death GO:0016265 284 0.012
oocyte construction GO:0007308 112 0.012
regulation of dna metabolic process GO:0051052 34 0.012
positive regulation of cell motility GO:2000147 3 0.012
telencephalon development GO:0021537 2 0.012
defense response to bacterium GO:0042742 178 0.011
glutathione metabolic process GO:0006749 37 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of proteolysis GO:0030162 87 0.011
cell fate determination GO:0001709 91 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
protein transport GO:0015031 155 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
cell death GO:0008219 279 0.011
protein polymerization GO:0051258 42 0.011
metal ion transport GO:0030001 74 0.011
regulation of cell development GO:0060284 215 0.011
cellular amide metabolic process GO:0043603 80 0.011
spindle assembly involved in meiosis GO:0090306 20 0.011
retina development in camera type eye GO:0060041 4 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
actin filament based process GO:0030029 220 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
protein processing GO:0016485 68 0.011
protein targeting to peroxisome GO:0006625 2 0.011
cell fate specification GO:0001708 71 0.011
regulation of organelle organization GO:0033043 196 0.011
cytoplasm organization GO:0007028 64 0.011
cellular homeostasis GO:0019725 80 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
phosphorylation GO:0016310 294 0.011
response to pain GO:0048265 3 0.010
cell cycle phase transition GO:0044770 140 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
microtubule organizing center organization GO:0031023 168 0.010
developmental growth GO:0048589 280 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
dorsal closure GO:0007391 79 0.010
spermatid development GO:0007286 98 0.010
regulation of cellular response to stress GO:0080135 89 0.010
cellular response to starvation GO:0009267 61 0.010
cell cycle checkpoint GO:0000075 95 0.010
establishment of protein localization to peroxisome GO:0072663 2 0.010
dna damage checkpoint GO:0000077 78 0.010
cation homeostasis GO:0055080 51 0.010
response to copper ion GO:0046688 4 0.010
photoreceptor cell development GO:0042461 96 0.010

c(2)M disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
nervous system disease DOID:863 0 0.010