Drosophila melanogaster

80 known processes

mp (Dmel_CG42543)

multiplexin

(Aliases: Dmel\CG42543,Dmp,CG33171,CG8647,CT14872,CG42543,CG14822,Dmel_CG33171,Dmel_CG8647,CG8645)

mp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron projection guidance GO:0097485 241 0.978
axon guidance GO:0007411 233 0.971
axon development GO:0061564 297 0.964
motor neuron axon guidance GO:0008045 58 0.953
axonogenesis GO:0007409 290 0.951
chemotaxis GO:0006935 249 0.920
forebrain development GO:0030900 2 0.890
taxis GO:0042330 304 0.855
locomotory behavior GO:0007626 176 0.739
dendrite morphogenesis GO:0048813 199 0.718
central nervous system development GO:0007417 201 0.672
compound eye photoreceptor cell differentiation GO:0001751 140 0.636
compound eye photoreceptor fate commitment GO:0001752 36 0.600
actin cytoskeleton organization GO:0030036 206 0.520
transcription from rna polymerase ii promoter GO:0006366 368 0.517
imaginal disc derived appendage development GO:0048737 399 0.516
metal ion transport GO:0030001 74 0.477
regulation of cell death GO:0010941 173 0.473
telencephalon development GO:0021537 2 0.449
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.447
eye development GO:0001654 323 0.403
eye photoreceptor cell fate commitment GO:0042706 37 0.385
photoreceptor cell fate commitment GO:0046552 41 0.353
brain development GO:0007420 120 0.326
imaginal disc derived appendage morphogenesis GO:0035114 395 0.316
death GO:0016265 284 0.301
metal ion homeostasis GO:0055065 44 0.290
heart process GO:0003015 37 0.271
regulation of multicellular organismal development GO:2000026 414 0.265
erbb signaling pathway GO:0038127 58 0.248
head development GO:0060322 135 0.248
single organism behavior GO:0044708 391 0.245
skin development GO:0043588 65 0.232
photoreceptor cell differentiation GO:0046530 170 0.230
neuron recognition GO:0008038 101 0.223
compound eye morphogenesis GO:0001745 249 0.215
positive regulation of nervous system development GO:0051962 69 0.213
regulation of localization GO:0032879 275 0.207
dendrite development GO:0016358 204 0.205
eye antennal disc development GO:0035214 60 0.185
sensory organ morphogenesis GO:0090596 260 0.182
cell migration GO:0016477 238 0.176
eye morphogenesis GO:0048592 260 0.176
cation transport GO:0006812 110 0.175
cell death GO:0008219 279 0.172
antennal development GO:0007469 25 0.169
cell fate specification GO:0001708 71 0.166
courtship behavior GO:0007619 68 0.160
appendage development GO:0048736 401 0.160
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.158
striated muscle cell differentiation GO:0051146 90 0.157
post embryonic appendage morphogenesis GO:0035120 385 0.155
regulation of dendrite morphogenesis GO:0048814 28 0.154
appendage morphogenesis GO:0035107 397 0.154
cell recognition GO:0008037 102 0.149
regulation of programmed cell death GO:0043067 152 0.143
positive regulation of response to stimulus GO:0048584 323 0.135
actomyosin structure organization GO:0031032 56 0.132
regionalization GO:0003002 416 0.130
enzyme linked receptor protein signaling pathway GO:0007167 179 0.128
epidermis development GO:0008544 65 0.128
multi organism behavior GO:0051705 175 0.122
positive regulation of developmental process GO:0051094 143 0.120
divalent inorganic cation homeostasis GO:0072507 29 0.117
camera type eye development GO:0043010 4 0.117
sensory perception of mechanical stimulus GO:0050954 72 0.114
regulation of immune system process GO:0002682 176 0.108
eye photoreceptor cell differentiation GO:0001754 145 0.107
regulation of nervous system development GO:0051960 248 0.106
exocrine system development GO:0035272 162 0.104
male courtship behavior GO:0008049 63 0.103
positive regulation of macromolecule metabolic process GO:0010604 405 0.102
cation transmembrane transport GO:0098655 88 0.101
camera type eye morphogenesis GO:0048593 2 0.099
programmed cell death GO:0012501 257 0.097
positive regulation of cell development GO:0010720 61 0.096
apoptotic process GO:0006915 159 0.095
neuron fate commitment GO:0048663 50 0.095
regulation of anatomical structure morphogenesis GO:0022603 242 0.094
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.094
striated muscle cell development GO:0055002 50 0.093
positive regulation of rna biosynthetic process GO:1902680 266 0.091
male mating behavior GO:0060179 70 0.090
homeostatic process GO:0042592 199 0.089
immune response GO:0006955 246 0.088
circulatory system process GO:0003013 37 0.086
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.084
muscle structure development GO:0061061 224 0.083
ion transmembrane transport GO:0034220 122 0.082
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.081
retina development in camera type eye GO:0060041 4 0.077
positive regulation of rna metabolic process GO:0051254 271 0.077
positive regulation of biosynthetic process GO:0009891 316 0.077
regulation of locomotion GO:0040012 42 0.075
regulation of neuron differentiation GO:0045664 103 0.075
muscle cell development GO:0055001 50 0.075
regulation of neuron death GO:1901214 26 0.073
multicellular organismal reproductive behavior GO:0033057 110 0.072
biological adhesion GO:0022610 138 0.071
positive regulation of signaling GO:0023056 243 0.069
axon choice point recognition GO:0016198 26 0.069
positive regulation of nucleic acid templated transcription GO:1903508 266 0.068
chemical homeostasis GO:0048878 92 0.066
regulation of molecular function GO:0065009 217 0.065
mating GO:0007618 120 0.064
positive regulation of neurogenesis GO:0050769 41 0.064
salivary gland development GO:0007431 162 0.062
negative regulation of cellular metabolic process GO:0031324 382 0.058
striated muscle tissue development GO:0014706 27 0.057
muscle system process GO:0003012 21 0.057
actin filament based process GO:0030029 220 0.055
positive regulation of multicellular organismal process GO:0051240 143 0.055
multi organism reproductive behavior GO:0044705 121 0.055
transmembrane transport GO:0055085 139 0.053
regulation of neurogenesis GO:0050767 158 0.053
r7 cell differentiation GO:0045466 43 0.052
negative regulation of response to stimulus GO:0048585 258 0.052
regulation of metal ion transport GO:0010959 15 0.052
positive regulation of cell communication GO:0010647 250 0.052
regulation of intracellular signal transduction GO:1902531 236 0.049
response to oxygen containing compound GO:1901700 200 0.049
response to biotic stimulus GO:0009607 294 0.048
cognition GO:0050890 141 0.048
phosphorylation GO:0016310 294 0.048
cell motility GO:0048870 251 0.047
antennal morphogenesis GO:0048800 14 0.046
somatic muscle development GO:0007525 66 0.046
neurological system process GO:0050877 358 0.046
cellular response to chemical stimulus GO:0070887 199 0.046
positive regulation of cell differentiation GO:0045597 64 0.045
salivary gland morphogenesis GO:0007435 145 0.045
protein localization GO:0008104 284 0.043
neural retina development GO:0003407 4 0.043
blood circulation GO:0008015 26 0.041
positive regulation of cell death GO:0010942 69 0.041
regulation of apoptotic process GO:0042981 130 0.041
gland development GO:0048732 191 0.041
regulation of cell differentiation GO:0045595 302 0.040
negative regulation of signal transduction GO:0009968 206 0.040
compound eye development GO:0048749 307 0.040
cellular response to oxygen containing compound GO:1901701 79 0.039
regulation of phosphorus metabolic process GO:0051174 210 0.039
positive regulation of cellular component biogenesis GO:0044089 80 0.039
ion transport GO:0006811 145 0.038
sensory perception GO:0007600 196 0.038
negative regulation of cell communication GO:0010648 223 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.038
peripheral nervous system development GO:0007422 52 0.038
ion homeostasis GO:0050801 55 0.037
response to external biotic stimulus GO:0043207 293 0.037
heart contraction GO:0060047 26 0.036
negative regulation of gene expression GO:0010629 387 0.036
regulation of cell development GO:0060284 215 0.036
cation homeostasis GO:0055080 51 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
positive regulation of cell motility GO:2000147 3 0.034
positive regulation of gtpase activity GO:0043547 43 0.034
cellular response to endogenous stimulus GO:0071495 80 0.034
morphogenesis of an epithelium GO:0002009 276 0.034
response to organic substance GO:0010033 284 0.034
negative regulation of apoptotic process GO:0043066 63 0.033
regulation of mitotic cell cycle GO:0007346 190 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.032
cell type specific apoptotic process GO:0097285 38 0.032
intracellular signal transduction GO:0035556 300 0.032
muscle organ development GO:0007517 127 0.032
regulation of synaptic transmission GO:0050804 69 0.032
regulation of neuron apoptotic process GO:0043523 16 0.032
negative regulation of cellular biosynthetic process GO:0031327 277 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.030
cell adhesion GO:0007155 136 0.030
positive regulation of cellular catabolic process GO:0031331 95 0.029
regulation of neuron projection development GO:0010975 69 0.028
small molecule metabolic process GO:0044281 305 0.028
protein phosphorylation GO:0006468 169 0.028
synaptic transmission GO:0007268 288 0.027
regulation of cell shape GO:0008360 113 0.027
neuron death GO:0070997 27 0.027
gland morphogenesis GO:0022612 145 0.027
response to salt stress GO:0009651 11 0.027
embryonic organ development GO:0048568 50 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
calcium ion transport GO:0006816 24 0.026
axon midline choice point recognition GO:0016199 26 0.026
locomotor rhythm GO:0045475 56 0.026
negative regulation of cell death GO:0060548 81 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
multi multicellular organism process GO:0044706 123 0.025
epithelial cell differentiation GO:0030855 322 0.025
leg disc morphogenesis GO:0007478 80 0.025
embryonic hindgut morphogenesis GO:0048619 48 0.025
regulation of catabolic process GO:0009894 170 0.024
wing disc morphogenesis GO:0007472 344 0.024
regulation of immune response GO:0050776 118 0.024
organic substance transport GO:0071702 257 0.024
gastrulation with mouth forming first GO:0001703 36 0.024
positive regulation of immune response GO:0050778 63 0.024
dephosphorylation GO:0016311 51 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
mesodermal cell fate commitment GO:0001710 7 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
nucleotide metabolic process GO:0009117 161 0.023
protein transport GO:0015031 155 0.023
photoreceptor cell axon guidance GO:0072499 23 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
purine ribonucleoside metabolic process GO:0046128 127 0.023
calcium ion homeostasis GO:0055074 23 0.022
positive regulation of protein complex assembly GO:0031334 22 0.022
epidermal cell differentiation GO:0009913 51 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
adult behavior GO:0030534 137 0.022
divalent inorganic cation transport GO:0072511 30 0.022
positive regulation of locomotion GO:0040017 8 0.022
immune response activating signal transduction GO:0002757 2 0.022
reproductive behavior GO:0019098 122 0.021
positive regulation of catabolic process GO:0009896 105 0.021
mesoderm development GO:0007498 78 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
axon extension involved in axon guidance GO:0048846 10 0.021
regulation of cell growth GO:0001558 43 0.021
formation of anatomical boundary GO:0048859 37 0.021
hair cell differentiation GO:0035315 47 0.020
response to other organism GO:0051707 293 0.020
rho protein signal transduction GO:0007266 14 0.020
response to abiotic stimulus GO:0009628 341 0.020
ras protein signal transduction GO:0007265 88 0.020
positive regulation of phosphorylation GO:0042327 87 0.020
cellular response to organic substance GO:0071310 132 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
regulation of organelle organization GO:0033043 196 0.020
gliogenesis GO:0042063 80 0.020
regulation of heart contraction GO:0008016 21 0.020
regulation of anatomical structure size GO:0090066 163 0.020
axon target recognition GO:0007412 16 0.020
endocytosis GO:0006897 310 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
regulation of rho protein signal transduction GO:0035023 20 0.019
regulation of response to stress GO:0080134 200 0.019
regulation of cellular component size GO:0032535 98 0.019
divalent metal ion transport GO:0070838 26 0.019
body morphogenesis GO:0010171 2 0.019
sarcomere organization GO:0045214 26 0.019
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.019
cellular protein complex assembly GO:0043623 71 0.018
open tracheal system development GO:0007424 204 0.018
regulation of phosphorylation GO:0042325 147 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of membrane potential GO:0042391 35 0.018
respiratory system development GO:0060541 213 0.018
inositol lipid mediated signaling GO:0048017 4 0.017
establishment of protein localization GO:0045184 163 0.017
neuron apoptotic process GO:0051402 17 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
actin filament organization GO:0007015 126 0.017
phototaxis GO:0042331 21 0.017
monovalent inorganic cation transport GO:0015672 40 0.017
olfactory bulb axon guidance GO:0071678 3 0.017
protein secretion GO:0009306 45 0.017
regulation of axon extension involved in axon guidance GO:0048841 4 0.016
regulation of catalytic activity GO:0050790 185 0.016
cell growth GO:0016049 108 0.016
sensory organ boundary specification GO:0008052 22 0.016
developmental programmed cell death GO:0010623 138 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
regulation of cellular localization GO:0060341 136 0.016
immune system process GO:0002376 347 0.016
circadian rhythm GO:0007623 105 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.016
peptidyl amino acid modification GO:0018193 105 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
positive regulation of signal transduction GO:0009967 223 0.016
male courtship behavior veined wing generated song production GO:0045433 20 0.016
immune effector process GO:0002252 98 0.016
protein modification process GO:0036211 438 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
catabolic process GO:0009056 409 0.016
malpighian tubule morphogenesis GO:0007443 44 0.016
cell fate determination GO:0001709 91 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
mapk cascade GO:0000165 107 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.015
regulation of cell projection organization GO:0031344 92 0.015
cell proliferation GO:0008283 299 0.015
response to alcohol GO:0097305 95 0.015
long term memory GO:0007616 62 0.015
antimicrobial humoral response GO:0019730 99 0.015
cellular amine metabolic process GO:0044106 12 0.015
gastrulation involving germ band extension GO:0010004 36 0.015
regulation of cell proliferation GO:0042127 163 0.014
mating behavior GO:0007617 106 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
regulation of mapk cascade GO:0043408 92 0.014
purine nucleoside biosynthetic process GO:0042451 3 0.014
cellular protein localization GO:0034613 160 0.014
muscle contraction GO:0006936 13 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
glial cell differentiation GO:0010001 35 0.014
positive regulation of nucleoside metabolic process GO:0045979 47 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
cellular ion homeostasis GO:0006873 39 0.014
amine metabolic process GO:0009308 12 0.013
response to decreased oxygen levels GO:0036293 58 0.013
sensory perception of sound GO:0007605 56 0.013
regulation of response to external stimulus GO:0032101 115 0.013
regulation of neuronal synaptic plasticity GO:0048168 8 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
r8 cell differentiation GO:0045465 13 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
secretion by cell GO:0032940 101 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
regulation of hydrolase activity GO:0051336 97 0.013
circadian behavior GO:0048512 76 0.013
regulation of protein localization GO:0032880 76 0.013
regulation of protein metabolic process GO:0051246 256 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
positive regulation of neuron apoptotic process GO:0043525 1 0.013
mitotic cell cycle embryonic GO:0045448 38 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
response to endogenous stimulus GO:0009719 119 0.013
organic substance catabolic process GO:1901575 308 0.012
dna packaging GO:0006323 91 0.012
inorganic cation transmembrane transport GO:0098662 61 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
regulation of ion transport GO:0043269 39 0.012
lateral inhibition GO:0046331 206 0.012
positive regulation of gene expression GO:0010628 290 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
response to copper ion GO:0046688 4 0.012
larval behavior GO:0030537 42 0.012
positive regulation of molecular function GO:0044093 136 0.012
heart development GO:0007507 82 0.012
hindbrain development GO:0030902 2 0.012
learning or memory GO:0007611 141 0.012
male courtship behavior veined wing vibration GO:0016545 21 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
hindgut morphogenesis GO:0007442 58 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
response to oxygen levels GO:0070482 59 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
synapse organization GO:0050808 196 0.012
ribonucleotide catabolic process GO:0009261 109 0.011
negative regulation of signaling GO:0023057 219 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
skeletal muscle organ development GO:0060538 48 0.011
tube morphogenesis GO:0035239 191 0.011
eye antennal disc morphogenesis GO:0007455 34 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
cardiovascular system development GO:0072358 82 0.011
regulation of cell size GO:0008361 63 0.011
renal tubule development GO:0061326 64 0.011
localization of cell GO:0051674 257 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
intracellular protein transport GO:0006886 104 0.011
necrotic cell death GO:0070265 1 0.011
regulation of behavior GO:0050795 75 0.011
circulatory system development GO:0072359 82 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
regulation of purine nucleotide catabolic process GO:0033121 48 0.010
negative regulation of phosphate metabolic process GO:0045936 45 0.010
salivary gland histolysis GO:0035070 88 0.010
cellular response to oxygen levels GO:0071453 30 0.010

mp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.094
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
nervous system disease DOID:863 0 0.010