Drosophila melanogaster

37 known processes

proPO-A1 (Dmel_CG42639)

prophenol oxidase A1

(Aliases: DoxA1,Mox,CG5779,pro-A,Dox-A1,Dmel_CG5779,Phox,DmePPOA1,proPO54,i12,A1,proPO,proPO A[[1]],A[[1]],CG42639,PO A1,PPO1,Dmel\CG42639,pro-POA[[1]],ProPO A1,pro-PO)

proPO-A1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
melanotic encapsulation of foreign target GO:0035011 30 1.000
melanin metabolic process GO:0006582 47 0.998
encapsulation of foreign target GO:0035010 38 0.992
secondary metabolic process GO:0019748 75 0.990
pigment metabolic process GO:0042440 84 0.981
defense response to fungus GO:0050832 48 0.979
intracellular protein transmembrane transport GO:0065002 4 0.969
response to fungus GO:0009620 50 0.923
melanization defense response GO:0035006 45 0.914
organic hydroxy compound metabolic process GO:1901615 83 0.856
defense response GO:0006952 300 0.856
neuron projection guidance GO:0097485 241 0.834
immune system process GO:0002376 347 0.834
immune response GO:0006955 246 0.795
innate immune response GO:0045087 144 0.784
immune effector process GO:0002252 98 0.772
cell recognition GO:0008037 102 0.718
intracellular protein transmembrane import GO:0044743 4 0.664
storage protein import into fat body GO:0015032 2 0.664
lateral inhibition GO:0046331 206 0.541
defense response to bacterium GO:0042742 178 0.451
axon development GO:0061564 297 0.443
chemotaxis GO:0006935 249 0.431
response to biotic stimulus GO:0009607 294 0.415
phenol containing compound metabolic process GO:0018958 57 0.397
catabolic process GO:0009056 409 0.384
response to external biotic stimulus GO:0043207 293 0.383
motor neuron axon guidance GO:0008045 58 0.379
protein import GO:0017038 55 0.374
axon guidance GO:0007411 233 0.356
defense response to other organism GO:0098542 225 0.336
protein transmembrane transport GO:0071806 4 0.322
hormone catabolic process GO:0042447 3 0.298
hemolymph coagulation GO:0042381 10 0.248
cellular catabolic process GO:0044248 372 0.231
taxis GO:0042330 304 0.214
protein localization GO:0008104 284 0.188
regulation of body fluid levels GO:0050878 14 0.174
humoral immune response GO:0006959 117 0.169
single organism catabolic process GO:0044712 228 0.165
wound healing GO:0042060 75 0.163
acetate ester metabolic process GO:1900619 2 0.159
single organism intracellular transport GO:1902582 207 0.156
small molecule metabolic process GO:0044281 305 0.143
response to oxygen containing compound GO:1901700 200 0.133
neuron recognition GO:0008038 101 0.131
imaginal disc derived appendage development GO:0048737 399 0.126
vesicle mediated transport GO:0016192 381 0.119
axonogenesis GO:0007409 290 0.114
acylglycerol catabolic process GO:0046464 3 0.108
organic substance catabolic process GO:1901575 308 0.107
establishment of localization in cell GO:0051649 402 0.106
phagocytosis GO:0006909 215 0.104
defense response to gram positive bacterium GO:0050830 41 0.102
cell cell signaling involved in cell fate commitment GO:0045168 210 0.101
appendage development GO:0048736 401 0.098
response to other organism GO:0051707 293 0.093
organic substance transport GO:0071702 257 0.091
courtship behavior GO:0007619 68 0.090
response to bacterium GO:0009617 198 0.089
multicellular organismal aging GO:0010259 140 0.088
negative chemotaxis GO:0050919 15 0.087
behavioral response to ethanol GO:0048149 49 0.087
organonitrogen compound metabolic process GO:1901564 318 0.082
mating GO:0007618 120 0.079
endocytosis GO:0006897 310 0.077
single organism behavior GO:0044708 391 0.077
male mating behavior GO:0060179 70 0.076
post embryonic appendage morphogenesis GO:0035120 385 0.075
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.072
multi multicellular organism process GO:0044706 123 0.072
multi organism reproductive behavior GO:0044705 121 0.071
ethanolamine containing compound metabolic process GO:0042439 4 0.069
mating behavior GO:0007617 106 0.066
response to organic substance GO:0010033 284 0.064
synaptic transmission GO:0007268 288 0.064
choline metabolic process GO:0019695 1 0.063
oxoacid metabolic process GO:0043436 103 0.062
lipid metabolic process GO:0006629 121 0.062
secondary metabolite biosynthetic process GO:0044550 24 0.062
neurotransmitter catabolic process GO:0042135 1 0.060
carboxylic acid metabolic process GO:0019752 92 0.059
lipid catabolic process GO:0016042 21 0.058
cellular lipid metabolic process GO:0044255 83 0.056
regionalization GO:0003002 416 0.055
imaginal disc derived wing morphogenesis GO:0007476 337 0.055
cellular amine metabolic process GO:0044106 12 0.053
cellular macromolecule localization GO:0070727 220 0.052
wing disc morphogenesis GO:0007472 344 0.052
adult behavior GO:0030534 137 0.052
reproductive behavior GO:0019098 122 0.052
innate immune response activating signal transduction GO:0002758 2 0.049
immune response regulating signaling pathway GO:0002764 2 0.049
intracellular transport GO:0046907 228 0.048
pattern recognition receptor signaling pathway GO:0002221 2 0.048
synaptic target recognition GO:0008039 45 0.048
acylglycerol biosynthetic process GO:0046463 2 0.047
multi organism behavior GO:0051705 175 0.047
response to lipopolysaccharide GO:0032496 4 0.047
glycerolipid catabolic process GO:0046503 3 0.046
neurotransmitter metabolic process GO:0042133 2 0.046
pheromone biosynthetic process GO:0042811 3 0.046
negative regulation of developmental process GO:0051093 201 0.045
triglyceride catabolic process GO:0019433 3 0.045
organophosphate metabolic process GO:0019637 195 0.044
appendage morphogenesis GO:0035107 397 0.044
cellular protein localization GO:0034613 160 0.043
amine metabolic process GO:0009308 12 0.043
ovarian follicle cell development GO:0030707 248 0.043
peptide metabolic process GO:0006518 80 0.042
organonitrogen compound catabolic process GO:1901565 128 0.041
nuclear division GO:0000280 332 0.040
determination of adult lifespan GO:0008340 137 0.040
organic acid metabolic process GO:0006082 103 0.040
cell migration GO:0016477 238 0.039
detection of monosaccharide stimulus GO:0034287 1 0.038
response to abiotic stimulus GO:0009628 341 0.037
protein modification process GO:0036211 438 0.037
protein transport GO:0015031 155 0.037
neutral lipid catabolic process GO:0046461 3 0.037
cellular response to lipopolysaccharide GO:0071222 3 0.037
regulation of response to external stimulus GO:0032101 115 0.036
cholesterol homeostasis GO:0042632 3 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
regulation of cellular response to stress GO:0080135 89 0.035
peptidoglycan catabolic process GO:0009253 3 0.035
transmembrane transport GO:0055085 139 0.035
response to glucose GO:0009749 2 0.034
immune response activating signal transduction GO:0002757 2 0.034
response to endogenous stimulus GO:0009719 119 0.034
cellular response to organic substance GO:0071310 132 0.034
response to organonitrogen compound GO:0010243 75 0.033
phosphorylation GO:0016310 294 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
regulation of multicellular organismal development GO:2000026 414 0.032
male gamete generation GO:0048232 201 0.031
positive regulation of biosynthetic process GO:0009891 316 0.031
neurological system process GO:0050877 358 0.031
cellular lipid catabolic process GO:0044242 16 0.031
heterocycle catabolic process GO:0046700 166 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
cellular modified amino acid metabolic process GO:0006575 45 0.030
regulation of transport GO:0051049 181 0.030
positive regulation of macromolecule metabolic process GO:0010604 405 0.030
macromolecule catabolic process GO:0009057 161 0.029
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.029
regulation of multi organism process GO:0043900 131 0.028
cellular response to molecule of bacterial origin GO:0071219 3 0.028
response to hexose GO:0009746 3 0.028
lipid storage GO:0019915 38 0.028
homeostatic process GO:0042592 199 0.028
negative regulation of nervous system development GO:0051961 92 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
proteolysis GO:0006508 192 0.027
ameboidal type cell migration GO:0001667 151 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
neutral lipid biosynthetic process GO:0046460 2 0.026
g protein coupled receptor signaling pathway GO:0007186 136 0.026
amine catabolic process GO:0009310 1 0.026
chemosensory behavior GO:0007635 106 0.026
response to nitrogen compound GO:1901698 90 0.026
circadian rhythm GO:0007623 105 0.025
single organism biosynthetic process GO:0044711 206 0.025
organelle fission GO:0048285 340 0.025
establishment of protein localization GO:0045184 163 0.025
purine ribonucleotide metabolic process GO:0009150 145 0.025
regulation of phosphate metabolic process GO:0019220 210 0.024
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.024
response to monosaccharide GO:0034284 4 0.024
apical junction assembly GO:0043297 32 0.024
cellular response to oxygen containing compound GO:1901701 79 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
response to heat GO:0009408 63 0.024
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.024
oxidation reduction process GO:0055114 123 0.024
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.023
phototaxis GO:0042331 21 0.023
gliogenesis GO:0042063 80 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
multicellular organismal reproductive behavior GO:0033057 110 0.023
regulation of cell cycle GO:0051726 291 0.023
phospholipid homeostasis GO:0055091 1 0.023
epithelial cell differentiation GO:0030855 322 0.022
carbohydrate metabolic process GO:0005975 82 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
compound eye morphogenesis GO:0001745 249 0.022
glycoprotein biosynthetic process GO:0009101 41 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
detection of glucose GO:0051594 1 0.021
triglyceride biosynthetic process GO:0019432 2 0.021
acetaldehyde metabolic process GO:0006117 5 0.021
epithelial cell development GO:0002064 274 0.021
response to alcohol GO:0097305 95 0.021
aromatic compound catabolic process GO:0019439 166 0.021
cell motility GO:0048870 251 0.021
acetylcholine catabolic process GO:0006581 1 0.021
purine nucleoside metabolic process GO:0042278 127 0.021
regulation of response to stress GO:0080134 200 0.021
cellular ketone metabolic process GO:0042180 24 0.020
chromosome segregation GO:0007059 157 0.020
nad metabolic process GO:0019674 1 0.020
regulation of localization GO:0032879 275 0.020
intracellular signal transduction GO:0035556 300 0.020
regulation of lipid transport GO:0032368 3 0.020
regulation of sterol transport GO:0032371 1 0.020
sensory organ morphogenesis GO:0090596 260 0.020
response to lipid GO:0033993 38 0.020
nucleoside metabolic process GO:0009116 127 0.020
cellular protein modification process GO:0006464 438 0.020
heart development GO:0007507 82 0.019
cellular biogenic amine catabolic process GO:0042402 1 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
sensory perception GO:0007600 196 0.019
regulation of response to biotic stimulus GO:0002831 63 0.019
steroid catabolic process GO:0006706 1 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
cellular response to endogenous stimulus GO:0071495 80 0.018
antimicrobial humoral response GO:0019730 99 0.018
border follicle cell migration GO:0007298 113 0.018
regulation of phosphorylation GO:0042325 147 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
cellular response to biotic stimulus GO:0071216 4 0.018
developmental growth GO:0048589 280 0.018
hemostasis GO:0007599 10 0.018
regulation of nervous system development GO:0051960 248 0.018
response to peptidoglycan GO:0032494 2 0.018
response to extracellular stimulus GO:0009991 116 0.018
acetylcholine metabolic process GO:0008291 2 0.018
negative regulation of signal transduction GO:0009968 206 0.018
anion homeostasis GO:0055081 3 0.017
anatomical structure homeostasis GO:0060249 97 0.017
regulation of anatomical structure size GO:0090066 163 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
eye morphogenesis GO:0048592 260 0.017
sleep GO:0030431 49 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
response to temperature stimulus GO:0009266 106 0.017
body morphogenesis GO:0010171 2 0.017
lipid localization GO:0010876 54 0.017
open tracheal system development GO:0007424 204 0.017
response to organophosphorus GO:0046683 2 0.017
maintenance of location GO:0051235 73 0.016
compound eye development GO:0048749 307 0.016
tissue migration GO:0090130 155 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
ovarian follicle cell migration GO:0007297 121 0.016
cellular amide metabolic process GO:0043603 80 0.016
spermatogenesis GO:0007283 200 0.016
protein complex assembly GO:0006461 200 0.016
camera type eye development GO:0043010 4 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
meiotic cell cycle process GO:1903046 132 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
cholesterol transport GO:0030301 2 0.015
primary alcohol metabolic process GO:0034308 2 0.015
forebrain development GO:0030900 2 0.015
regulation of lipid storage GO:0010883 22 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
macromolecular complex assembly GO:0065003 256 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
rhythmic behavior GO:0007622 76 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
positive regulation of transport GO:0051050 92 0.014
carbohydrate derivative biosynthetic process GO:1901137 85 0.014
death GO:0016265 284 0.014
epithelium migration GO:0090132 148 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
regulation of defense response GO:0031347 102 0.014
localization of cell GO:0051674 257 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
cellular response to ethanol GO:0071361 4 0.014
cellular biogenic amine metabolic process GO:0006576 9 0.014
regulation of circadian rhythm GO:0042752 49 0.014
respiratory system development GO:0060541 213 0.014
mapk cascade GO:0000165 107 0.014
dna metabolic process GO:0006259 227 0.014
monocarboxylic acid metabolic process GO:0032787 29 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
small molecule catabolic process GO:0044282 21 0.013
positive regulation of cell communication GO:0010647 250 0.013
hair cell differentiation GO:0035315 47 0.013
positive regulation of response to external stimulus GO:0032103 44 0.013
organic hydroxy compound catabolic process GO:1901616 4 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
positive regulation of defense response GO:0031349 59 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
regulation of cholesterol transport GO:0032374 1 0.013
regulation of catalytic activity GO:0050790 185 0.013
positive regulation of signaling GO:0023056 243 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
response to ethanol GO:0045471 59 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
cellular component disassembly GO:0022411 46 0.013
amide biosynthetic process GO:0043604 42 0.013
protein complex biogenesis GO:0070271 201 0.013
energy taxis GO:0009453 21 0.013
positive regulation of catabolic process GO:0009896 105 0.012
phosphatidylethanolamine metabolic process GO:0046337 1 0.012
leg disc morphogenesis GO:0007478 80 0.012
nucleotide catabolic process GO:0009166 109 0.012
acid secretion GO:0046717 1 0.012
regulation of behavior GO:0050795 75 0.012
nitrogen compound transport GO:0071705 85 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
peptidyl amino acid modification GO:0018193 105 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of cell proliferation GO:0042127 163 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.012
regulation of stress activated mapk cascade GO:0032872 41 0.012
aging GO:0007568 143 0.012
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.012
actin filament based process GO:0030029 220 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.012
cellular hormone metabolic process GO:0034754 23 0.012
hormone metabolic process GO:0042445 33 0.012
regulation of mapk cascade GO:0043408 92 0.012
epidermis development GO:0008544 65 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
signal release GO:0023061 49 0.012
eggshell chorion assembly GO:0007306 66 0.012
positive regulation of molecular function GO:0044093 136 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.011
purine containing compound metabolic process GO:0072521 155 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
negative regulation of cell cycle GO:0045786 116 0.011
response to copper ion GO:0046688 4 0.011
cell adhesion GO:0007155 136 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
toxin metabolic process GO:0009404 2 0.011
response to growth factor GO:0070848 31 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
detection of stimulus GO:0051606 156 0.011
wnt signaling pathway GO:0016055 98 0.011
regulation of catabolic process GO:0009894 170 0.011
segmentation GO:0035282 207 0.011
drinking behavior GO:0042756 2 0.011
organelle assembly GO:0070925 198 0.011
juvenile hormone metabolic process GO:0006716 3 0.011
nucleoside catabolic process GO:0009164 112 0.011
kidney development GO:0001822 3 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
synaptic target inhibition GO:0016201 11 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
regulation of humoral immune response GO:0002920 51 0.011
chorion containing eggshell formation GO:0007304 105 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
oxidoreduction coenzyme metabolic process GO:0006733 2 0.011
response to organic cyclic compound GO:0014070 89 0.011
cell death GO:0008219 279 0.011
proximal distal pattern formation GO:0009954 15 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.010
monocarboxylic acid transport GO:0015718 3 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
gtp catabolic process GO:0006184 72 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
positive regulation of nucleoside metabolic process GO:0045979 47 0.010
circadian sleep wake cycle process GO:0022410 24 0.010
secretion GO:0046903 109 0.010
stress activated protein kinase signaling cascade GO:0031098 55 0.010
secretion by cell GO:0032940 101 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
positive regulation of immune response GO:0050778 63 0.010
telencephalon development GO:0021537 2 0.010
regulation of transferase activity GO:0051338 58 0.010
positive regulation of cell motility GO:2000147 3 0.010
regulation of cellular amide metabolic process GO:0034248 39 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
eggshell formation GO:0030703 105 0.010
alditol phosphate metabolic process GO:0052646 2 0.010

proPO-A1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hair disease DOID:421 0 0.211
disease of anatomical entity DOID:7 0 0.211
integumentary system disease DOID:16 0 0.211
hypotrichosis DOID:4535 0 0.211
disease of metabolism DOID:0014667 0 0.147
familial hypertriglyceridemia DOID:0050527 0 0.147
lipid metabolism disorder DOID:3146 0 0.147
inherited metabolic disorder DOID:655 0 0.147
diabetes mellitus DOID:9351 0 0.059
carbohydrate metabolism disease DOID:0050013 0 0.059
glucose metabolism disease DOID:4194 0 0.059
acquired metabolic disease DOID:0060158 0 0.059
type 2 diabetes mellitus DOID:9352 0 0.024
familial lipoprotein lipase deficiency DOID:14118 0 0.024
familial hyperlipidemia DOID:1168 0 0.024
nervous system disease DOID:863 0 0.020
familial combined hyperlipidemia DOID:13809 0 0.017
central nervous system disease DOID:331 0 0.014
artery disease DOID:0050828 0 0.010
vascular disease DOID:178 0 0.010
cardiovascular system disease DOID:1287 0 0.010
neurodegenerative disease DOID:1289 0 0.010