Drosophila melanogaster

96 known processes

Hsc70-4 (Dmel_CG4264)

Heat shock protein cognate 4

(Aliases: Hsc4p,HSC4,Hsc70,scd,Hsc-4,Hsp70,bs17d06.y1,l(3)L3929,HSC70,hsc70,Dmel\CG4264,dhsc70,hsp70,E(nd)195,hsc70-4,i190,l(3)03550,Hsc4,CG4264,BAP74,E(csp)1545,HSC-70,hsc4,anon-WO0118547.237,l(3)j7A4)

Hsc70-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression epigenetic GO:0040029 128 0.975
growth GO:0040007 359 0.906
Human Zebrafish
response to organic substance GO:0010033 284 0.819
gene silencing GO:0016458 138 0.796
embryonic morphogenesis GO:0048598 206 0.711
respiratory system development GO:0060541 213 0.684
negative regulation of cellular metabolic process GO:0031324 382 0.634
Human Rat
regulation of developmental growth GO:0048638 174 0.576
nuclear division GO:0000280 332 0.575
Mouse
head development GO:0060322 135 0.543
regulation of cellular protein metabolic process GO:0032268 243 0.540
Human Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.521
posttranscriptional regulation of gene expression GO:0010608 145 0.495
spermatid differentiation GO:0048515 114 0.490
Mouse
regulation of growth GO:0040008 233 0.477
Human
negative regulation of signaling GO:0023057 219 0.450
Human
taxis GO:0042330 304 0.421
negative regulation of cellular biosynthetic process GO:0031327 277 0.406
Human
heart development GO:0007507 82 0.396
eye development GO:0001654 323 0.392
intracellular signal transduction GO:0035556 300 0.385
sensory organ morphogenesis GO:0090596 260 0.376
cell migration GO:0016477 238 0.366
cell motility GO:0048870 251 0.364
protein modification process GO:0036211 438 0.357
Human Mouse
cellular protein modification process GO:0006464 438 0.354
Human Mouse
tube development GO:0035295 244 0.347
cellular macromolecule localization GO:0070727 220 0.324
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.316
Human Yeast Mouse Rat Worm
cell proliferation GO:0008283 299 0.316
Human
lateral inhibition GO:0046331 206 0.309
epithelial cell differentiation GO:0030855 322 0.304
negative regulation of cell communication GO:0010648 223 0.304
Human
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.296
male gamete generation GO:0048232 201 0.292
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.289
cellular macromolecule catabolic process GO:0044265 136 0.287
Human Yeast
digestive system development GO:0055123 149 0.286
apoptotic signaling pathway GO:0097190 27 0.285
Human
mitotic nuclear division GO:0007067 213 0.278
regulation of catabolic process GO:0009894 170 0.277
death GO:0016265 284 0.276
Human Rat Worm
cellular response to chemical stimulus GO:0070887 199 0.267
negative regulation of transcription dna templated GO:0045892 237 0.267
Human
regulation of cell differentiation GO:0045595 302 0.265
Human Rat
organic substance catabolic process GO:1901575 308 0.262
Human Yeast Mouse Rat Worm
spermatid development GO:0007286 98 0.260
Mouse
proteolysis GO:0006508 192 0.250
Yeast Rat
developmental programmed cell death GO:0010623 138 0.246
purine containing compound metabolic process GO:0072521 155 0.245
Human Yeast Mouse Rat Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.239
multicellular organismal aging GO:0010259 140 0.238
Worm
localization of cell GO:0051674 257 0.237
nucleotide metabolic process GO:0009117 161 0.235
Human Yeast Mouse Rat Worm
axon guidance GO:0007411 233 0.235
segmentation GO:0035282 207 0.234
macromolecular complex assembly GO:0065003 256 0.232
single organism intracellular transport GO:1902582 207 0.223
Yeast Worm
negative regulation of gene expression GO:0010629 387 0.223
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.222
Human
phosphorylation GO:0016310 294 0.205
Mouse
gland development GO:0048732 191 0.204
positive regulation of gene expression GO:0010628 290 0.197
Mouse
regulation of multicellular organismal development GO:2000026 414 0.188
Human Rat
regulation of organelle organization GO:0033043 196 0.185
establishment of localization in cell GO:0051649 402 0.185
cellular catabolic process GO:0044248 372 0.183
Human Yeast Mouse Rat Worm
eye morphogenesis GO:0048592 260 0.179
regulation of intracellular signal transduction GO:1902531 236 0.177
organelle fission GO:0048285 340 0.177
Mouse
cell recognition GO:0008037 102 0.173
transcription from rna polymerase ii promoter GO:0006366 368 0.170
regulation of phosphate metabolic process GO:0019220 210 0.167
Mouse
regulation of protein metabolic process GO:0051246 256 0.166
Human Mouse Rat
positive regulation of multicellular organism growth GO:0040018 21 0.166
brain development GO:0007420 120 0.163
chromatin organization GO:0006325 207 0.162
cell division GO:0051301 248 0.161
open tracheal system development GO:0007424 204 0.161
negative regulation of cellular protein metabolic process GO:0032269 85 0.161
Human Rat
ribonucleoside catabolic process GO:0042454 112 0.158
Human Yeast Mouse Rat Worm
macromolecule catabolic process GO:0009057 161 0.157
Human Yeast
autophagy GO:0006914 108 0.153
cell death GO:0008219 279 0.151
Human Rat Worm
modification dependent macromolecule catabolic process GO:0043632 79 0.147
immune system process GO:0002376 347 0.144
Human Rat
regulation of epithelial cell proliferation GO:0050678 4 0.144
negative regulation of intracellular signal transduction GO:1902532 57 0.144
regulation of cellular response to stress GO:0080135 89 0.141
purine ribonucleoside catabolic process GO:0046130 112 0.141
Human Yeast Mouse Rat Worm
vesicle mediated transport GO:0016192 381 0.141
central nervous system development GO:0007417 201 0.140
protein maturation GO:0051604 71 0.139
Rat
positive regulation of nucleic acid templated transcription GO:1903508 266 0.136
endocytosis GO:0006897 310 0.135
Worm
digestive tract development GO:0048565 149 0.135
organic substance transport GO:0071702 257 0.133
Yeast
negative regulation of signal transduction GO:0009968 206 0.133
Human
negative regulation of phosphorylation GO:0042326 35 0.133
nucleoside triphosphate metabolic process GO:0009141 120 0.130
Human Yeast Mouse Rat Worm
determination of adult lifespan GO:0008340 137 0.127
Worm
positive regulation of signaling GO:0023056 243 0.126
negative regulation of cell cycle GO:0045786 116 0.126
Worm
single organism cellular localization GO:1902580 180 0.123
Yeast
cellular response to organic substance GO:0071310 132 0.122
catabolic process GO:0009056 409 0.120
Human Yeast Mouse Rat Worm
regulation of phosphorylation GO:0042325 147 0.120
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.120
regulation of localization GO:0032879 275 0.119
regulation of cell death GO:0010941 173 0.119
Human Rat
gene silencing by rna GO:0031047 57 0.115
regulation of proteolysis GO:0030162 87 0.114
Rat
developmental growth GO:0048589 280 0.114
Zebrafish
chromosome organization GO:0051276 360 0.114
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.114
body morphogenesis GO:0010171 2 0.112
Worm
posttranscriptional gene silencing by rna GO:0035194 45 0.112
translation GO:0006412 69 0.108
Yeast
ubiquitin dependent protein catabolic process GO:0006511 78 0.107
regulation of cellular catabolic process GO:0031329 157 0.106
protein localization GO:0008104 284 0.106
Yeast
response to oxygen containing compound GO:1901700 200 0.106
Rat
autophagic cell death GO:0048102 83 0.105
response to nitrogen compound GO:1901698 90 0.103
cellular protein catabolic process GO:0044257 83 0.101
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.100
Yeast
response to organonitrogen compound GO:0010243 75 0.100
regulation of cell cycle GO:0051726 291 0.099
Mouse Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.096
purine nucleoside metabolic process GO:0042278 127 0.095
Human Yeast Mouse Rat Worm
regulation of cell morphogenesis GO:0022604 163 0.094
regulation of transport GO:0051049 181 0.091
regulation of cell division GO:0051302 72 0.091
morphogenesis of an epithelium GO:0002009 276 0.089
anterior posterior axis specification GO:0009948 109 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.089
Mouse
response to alcohol GO:0097305 95 0.088
Rat
organonitrogen compound catabolic process GO:1901565 128 0.088
Human Yeast Mouse Rat Worm
negative regulation of rna metabolic process GO:0051253 251 0.088
Human
signal transduction by phosphorylation GO:0023014 107 0.088
ovarian follicle cell development GO:0030707 248 0.087
gonad development GO:0008406 50 0.085
neuron projection guidance GO:0097485 241 0.085
positive regulation of cell communication GO:0010647 250 0.084
cell maturation GO:0048469 144 0.084
negative regulation of response to stimulus GO:0048585 258 0.082
Human
regulation of multicellular organism growth GO:0040014 40 0.082
glycosyl compound metabolic process GO:1901657 127 0.081
Human Yeast Mouse Rat Worm
regulation of phosphorus metabolic process GO:0051174 210 0.080
Mouse
response to endogenous stimulus GO:0009719 119 0.080
positive regulation of cellular protein metabolic process GO:0032270 118 0.079
Mouse
regulation of response to external stimulus GO:0032101 115 0.079
regulation of cellular localization GO:0060341 136 0.078
negative regulation of multicellular organismal process GO:0051241 142 0.078
Rat
positive regulation of signal transduction GO:0009967 223 0.078
negative regulation of biosynthetic process GO:0009890 277 0.077
Human
gastrulation GO:0007369 70 0.076
cognition GO:0050890 141 0.076
spermatogenesis GO:0007283 200 0.076
Mouse
protein transport GO:0015031 155 0.076
Yeast
circulatory system development GO:0072359 82 0.075
nucleobase containing small molecule metabolic process GO:0055086 174 0.074
Human Yeast Mouse Rat Worm
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.072
circadian rhythm GO:0007623 105 0.071
regulation of neurogenesis GO:0050767 158 0.070
Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.070
negative regulation of cell proliferation GO:0008285 69 0.069
Human
reproductive system development GO:0061458 74 0.068
lipid localization GO:0010876 54 0.067
mapk cascade GO:0000165 107 0.065
organonitrogen compound metabolic process GO:1901564 318 0.065
Human Yeast Mouse Rat Worm
regulation of response to stress GO:0080134 200 0.064
modification dependent protein catabolic process GO:0019941 78 0.064
imaginal disc derived appendage development GO:0048737 399 0.063
chromatin silencing GO:0006342 76 0.062
regulation of cellular component biogenesis GO:0044087 201 0.061
Human
eye antennal disc development GO:0035214 60 0.061
oocyte development GO:0048599 124 0.061
appendage development GO:0048736 401 0.061
negative regulation of developmental process GO:0051093 201 0.060
negative regulation of epithelial cell proliferation GO:0050680 4 0.060
tissue death GO:0016271 102 0.060
nucleoside metabolic process GO:0009116 127 0.059
Human Yeast Mouse Rat Worm
cellular component disassembly GO:0022411 46 0.057
Yeast Mouse
regulation of response to oxidative stress GO:1902882 4 0.057
sex differentiation GO:0007548 81 0.057
embryo development ending in birth or egg hatching GO:0009792 152 0.057
protein complex assembly GO:0006461 200 0.056
digestive tract morphogenesis GO:0048546 127 0.055
positive regulation of multicellular organismal process GO:0051240 143 0.055
Human Rat
ribonucleoside metabolic process GO:0009119 127 0.055
Human Yeast Mouse Rat Worm
rhythmic process GO:0048511 106 0.054
cellular response to oxygen containing compound GO:1901701 79 0.053
negative regulation of cell differentiation GO:0045596 143 0.053
regulation of wnt signaling pathway GO:0030111 68 0.053
secretion by cell GO:0032940 101 0.053
wnt signaling pathway GO:0016055 98 0.053
cardiovascular system development GO:0072358 82 0.052
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.052
kidney development GO:0001822 3 0.051
locomotory behavior GO:0007626 176 0.051
proteasomal protein catabolic process GO:0010498 59 0.051
secretion GO:0046903 109 0.051
regulation of protein modification process GO:0031399 112 0.050
Human Mouse
positive regulation of protein metabolic process GO:0051247 128 0.050
Mouse
regulation of mitotic cell cycle GO:0007346 190 0.049
Worm
positive regulation of catabolic process GO:0009896 105 0.048
ribose phosphate metabolic process GO:0019693 145 0.048
Human Yeast Mouse Rat Worm
purine ribonucleotide metabolic process GO:0009150 145 0.048
Human Yeast Mouse Rat Worm
ribonucleoside triphosphate catabolic process GO:0009203 108 0.047
Human Yeast Mouse Rat Worm
jnk cascade GO:0007254 50 0.047
urogenital system development GO:0001655 72 0.046
carbohydrate derivative metabolic process GO:1901135 217 0.046
Human Yeast Mouse Rat Worm
multicellular organism growth GO:0035264 46 0.046
morphogenesis of a branching epithelium GO:0061138 45 0.045
purine ribonucleoside metabolic process GO:0046128 127 0.045
Human Yeast Mouse Rat Worm
gliogenesis GO:0042063 80 0.045
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.045
response to sterol GO:0036314 34 0.045
programmed cell death GO:0012501 257 0.045
Human Rat Worm
protein phosphorylation GO:0006468 169 0.044
Mouse
negative regulation of phosphorus metabolic process GO:0010563 45 0.044
positive regulation of catalytic activity GO:0043085 118 0.044
Mouse
neurological system process GO:0050877 358 0.044
sensory perception GO:0007600 196 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
organophosphate metabolic process GO:0019637 195 0.042
Human Yeast Mouse Rat Worm
organic cyclic compound catabolic process GO:1901361 168 0.041
Human Yeast Mouse Rat Worm
histolysis GO:0007559 102 0.041
negative regulation of cellular component organization GO:0051129 108 0.041
Human
apoptotic process GO:0006915 159 0.041
Human Rat Worm
regulation of apoptotic signaling pathway GO:2001233 10 0.039
Human
positive regulation of response to stimulus GO:0048584 323 0.039
Rat
positive regulation of growth GO:0045927 75 0.039
malpighian tubule development GO:0072002 64 0.039
response to hydrogen peroxide GO:0042542 11 0.039
establishment of protein localization GO:0045184 163 0.038
Yeast
purine nucleotide metabolic process GO:0006163 146 0.038
Human Yeast Mouse Rat Worm
oocyte anterior posterior axis specification GO:0007314 72 0.038
organelle assembly GO:0070925 198 0.037
epithelial cell migration GO:0010631 148 0.037
nucleoside monophosphate metabolic process GO:0009123 52 0.037
Human Yeast Mouse Rat Worm
cellular nitrogen compound catabolic process GO:0044270 165 0.036
Human Yeast Mouse Rat Worm
oxidation reduction process GO:0055114 123 0.036
regulation of cell proliferation GO:0042127 163 0.036
Human
purine nucleoside catabolic process GO:0006152 112 0.036
Human Yeast Mouse Rat Worm
trachea development GO:0060438 29 0.036
nucleoside triphosphate catabolic process GO:0009143 108 0.035
Human Yeast Mouse Rat Worm
cellular response to endogenous stimulus GO:0071495 80 0.035
post embryonic appendage morphogenesis GO:0035120 385 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.035
Human
dendrite development GO:0016358 204 0.035
covalent chromatin modification GO:0016569 106 0.035
dendrite morphogenesis GO:0048813 199 0.035
protein import into nucleus GO:0006606 51 0.034
Yeast
compound eye development GO:0048749 307 0.034
negative regulation of rna biosynthetic process GO:1902679 240 0.034
Human
autophagic vacuole assembly GO:0000045 2 0.034
induction of programmed cell death by ecdysone GO:0035078 12 0.034
glycosyl compound catabolic process GO:1901658 112 0.033
Human Yeast Mouse Rat Worm
nuclear body organization GO:0030575 6 0.033
small molecule metabolic process GO:0044281 305 0.033
Human Yeast Mouse Rat Worm
positive regulation of rna metabolic process GO:0051254 271 0.033
Mouse
centrosome organization GO:0051297 163 0.033
protein ubiquitination GO:0016567 70 0.032
Human
regulation of hydrolase activity GO:0051336 97 0.032
Rat
protein modification by small protein conjugation GO:0032446 79 0.032
Human
positive regulation of apoptotic signaling pathway GO:2001235 4 0.032
reproductive structure development GO:0048608 74 0.031
nucleotide catabolic process GO:0009166 109 0.031
Human Yeast Mouse Rat Worm
anterior posterior pattern specification GO:0009952 136 0.031
extracellular matrix disassembly GO:0022617 4 0.031
tube morphogenesis GO:0035239 191 0.031
purine nucleoside triphosphate catabolic process GO:0009146 108 0.031
Human Yeast Mouse Rat Worm
wing disc morphogenesis GO:0007472 344 0.031
protein catabolic process GO:0030163 101 0.031
Yeast
chromatin remodeling GO:0006338 72 0.031
response to peptide GO:1901652 29 0.031
oocyte construction GO:0007308 112 0.030
epithelial cell development GO:0002064 274 0.030
regulation of proteasomal protein catabolic process GO:0061136 39 0.030
pole plasm assembly GO:0007315 61 0.030
negative regulation of protein metabolic process GO:0051248 85 0.030
Human Rat
atp metabolic process GO:0046034 49 0.030
Human Yeast Mouse Rat Worm
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
regulation of cell cycle process GO:0010564 181 0.029
axis specification GO:0009798 167 0.029
purine nucleoside biosynthetic process GO:0042451 3 0.028
regulation of cellular component movement GO:0051270 42 0.028
embryonic development via the syncytial blastoderm GO:0001700 148 0.027
regulation of translation GO:0006417 56 0.027
positive regulation of cellular component organization GO:0051130 156 0.027
oxoacid metabolic process GO:0043436 103 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
Human Yeast Mouse Rat Worm
purine nucleoside triphosphate metabolic process GO:0009144 119 0.026
Human Yeast Mouse Rat Worm
stem cell development GO:0048864 79 0.026
asymmetric cell division GO:0008356 37 0.026
single organism biosynthetic process GO:0044711 206 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
cellular respiration GO:0045333 26 0.025
salivary gland cell autophagic cell death GO:0035071 83 0.025
renal system development GO:0072001 72 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
Human Yeast Mouse Rat Worm
negative regulation of growth GO:0045926 84 0.024
Human
purine nucleotide catabolic process GO:0006195 109 0.024
Human Yeast Mouse Rat Worm
oocyte axis specification GO:0007309 108 0.024
negative regulation of catalytic activity GO:0043086 42 0.024
Rat
chromatin modification GO:0016568 147 0.024
phagocytosis GO:0006909 215 0.024
maternal determination of anterior posterior axis embryo GO:0008358 74 0.024
purine containing compound catabolic process GO:0072523 112 0.024
Human Yeast Mouse Rat Worm
regulation of vesicle mediated transport GO:0060627 59 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
Human Yeast Mouse Rat Worm
stem cell division GO:0017145 69 0.024
response to external biotic stimulus GO:0043207 293 0.023
response to other organism GO:0051707 293 0.023
regulation of kinase activity GO:0043549 53 0.023
Mouse
maintenance of location GO:0051235 73 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
Human Yeast Mouse Rat Worm
negative regulation of mitotic cell cycle GO:0045930 109 0.023
Worm
posttranscriptional gene silencing GO:0016441 46 0.023
salivary gland histolysis GO:0035070 88 0.023
positive regulation of cell projection organization GO:0031346 29 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
Human Yeast Mouse Rat Worm
regulation of nervous system development GO:0051960 248 0.022
Rat
macroautophagy GO:0016236 42 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
Human
regulation of mapk cascade GO:0043408 92 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
Human Yeast Mouse Rat Worm
negative regulation of kinase activity GO:0033673 16 0.022
single organism nuclear import GO:1902593 51 0.021
Yeast
protein localization to organelle GO:0033365 82 0.021
Yeast
jak stat cascade GO:0007259 49 0.021
molting cycle GO:0042303 56 0.021
developmental maturation GO:0021700 172 0.021
salivary gland morphogenesis GO:0007435 145 0.021
neuron recognition GO:0008038 101 0.021
regulation of catalytic activity GO:0050790 185 0.021
Mouse Rat
cellular amide metabolic process GO:0043603 80 0.021
response to biotic stimulus GO:0009607 294 0.021
stem cell differentiation GO:0048863 117 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
Human Yeast Mouse Rat Worm
inter male aggressive behavior GO:0002121 60 0.020
regulation of cellular response to oxidative stress GO:1900407 4 0.020
microtubule organizing center organization GO:0031023 168 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
peptidyl amino acid modification GO:0018193 105 0.020
positive regulation of response to external stimulus GO:0032103 44 0.020
negative regulation of gene expression epigenetic GO:0045814 77 0.019
columnar cuboidal epithelial cell development GO:0002066 249 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
Human Yeast Mouse Rat Worm
response to hypoxia GO:0001666 53 0.019
development of primary sexual characteristics GO:0045137 50 0.019
appendage morphogenesis GO:0035107 397 0.019
negative regulation of phosphate metabolic process GO:0045936 45 0.019
peripheral nervous system development GO:0007422 52 0.019
regulation of protein catabolic process GO:0042176 55 0.019
eye antennal disc morphogenesis GO:0007455 34 0.019
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
oocyte differentiation GO:0009994 145 0.019
learning or memory GO:0007611 141 0.019
neural precursor cell proliferation GO:0061351 75 0.019
protein heterooligomerization GO:0051291 4 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
Mouse
anterior posterior axis specification embryo GO:0008595 103 0.018
regulation of notch signaling pathway GO:0008593 100 0.018
salivary gland development GO:0007431 162 0.018
regulation of protein ubiquitination GO:0031396 22 0.018
Human
dna metabolic process GO:0006259 227 0.018
protein complex biogenesis GO:0070271 201 0.018
regulation of cell shape GO:0008360 113 0.017
stem cell proliferation GO:0072089 88 0.017
purine nucleoside monophosphate metabolic process GO:0009126 50 0.017
Human Yeast Mouse Rat Worm
chromosome segregation GO:0007059 157 0.017
cell type specific apoptotic process GO:0097285 38 0.017
Rat
forebrain development GO:0030900 2 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
Human Rat
regulation of protein localization GO:0032880 76 0.017
positive regulation of molecular function GO:0044093 136 0.017
Mouse
positive regulation of gtp catabolic process GO:0033126 43 0.017
single organism catabolic process GO:0044712 228 0.017
Human Yeast Mouse Rat Worm
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
Mouse
energy derivation by oxidation of organic compounds GO:0015980 32 0.016
epithelial cell migration open tracheal system GO:0007427 32 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
Yeast
tissue migration GO:0090130 155 0.016
wound healing GO:0042060 75 0.016
Zebrafish
tissue morphogenesis GO:0048729 297 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
negative regulation of mapk cascade GO:0043409 23 0.016
epithelium migration GO:0090132 148 0.016
cytoplasmic transport GO:0016482 130 0.016
Yeast
negative regulation of cellular response to oxidative stress GO:1900408 1 0.016
response to wounding GO:0009611 94 0.016
Zebrafish
regulation of protein kinase activity GO:0045859 51 0.015
Mouse
negative regulation of cell death GO:0060548 81 0.015
Human Rat
positive regulation of phosphate metabolic process GO:0045937 139 0.015
Mouse
aromatic compound catabolic process GO:0019439 166 0.015
Human Yeast Mouse Rat Worm
positive regulation of developmental process GO:0051094 143 0.015
Human Rat
regulation of hemocyte proliferation GO:0035206 37 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
Human Yeast Mouse Rat Worm
epithelial tube morphogenesis GO:0060562 88 0.015
response to temperature stimulus GO:0009266 106 0.015
Human Yeast Worm
response to ketone GO:1901654 34 0.015
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.015
ameboidal type cell migration GO:0001667 151 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.015
Human Yeast Mouse Rat Worm
pole plasm rna localization GO:0007316 52 0.014
protein localization to nucleus GO:0034504 55 0.014
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 39 0.014
Human Yeast Mouse Rat Worm
response to decreased oxygen levels GO:0036293 58 0.014
glial cell development GO:0021782 27 0.014
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
Mouse
embryonic organ development GO:0048568 50 0.014
axonogenesis GO:0007409 290 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.014
regulation of protein processing GO:0070613 32 0.014
Rat
immune system development GO:0002520 57 0.013
Human
negative regulation of protein phosphorylation GO:0001933 17 0.013
regulation of molecular function GO:0065009 217 0.013
Mouse Rat
positive regulation of proteolysis GO:0045862 52 0.013
retina development in camera type eye GO:0060041 4 0.013
genitalia development GO:0048806 26 0.013
negative regulation of neuron death GO:1901215 18 0.013
negative regulation of organelle organization GO:0010639 56 0.013
organic acid metabolic process GO:0006082 103 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
intracellular protein transport GO:0006886 104 0.013
Yeast
negative regulation of transferase activity GO:0051348 18 0.012
regulation of imaginal disc growth GO:0045570 26 0.012
cellular protein localization GO:0034613 160 0.012
Yeast
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
Human
positive regulation of developmental growth GO:0048639 62 0.012
camera type eye morphogenesis GO:0048593 2 0.012
neuroblast proliferation GO:0007405 74 0.012
regulation of protein complex assembly GO:0043254 42 0.012
limb morphogenesis GO:0035108 1 0.012
regulation of autophagy GO:0010506 62 0.012
embryonic pattern specification GO:0009880 174 0.012
response to ecdysone GO:0035075 34 0.012
protein processing GO:0016485 68 0.012
Rat
negative regulation of protein modification process GO:0031400 29 0.011
Human
single organism behavior GO:0044708 391 0.011
positive regulation of nucleotide catabolic process GO:0030813 46 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
response to organic cyclic compound GO:0014070 89 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
response to endoplasmic reticulum stress GO:0034976 28 0.011
regulation of apoptotic process GO:0042981 130 0.011
Human Rat
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
aging GO:0007568 143 0.011
Worm
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
Human
negative regulation of response to oxidative stress GO:1902883 1 0.011
pole plasm mrna localization GO:0019094 49 0.011
endosomal transport GO:0016197 44 0.011
Worm
nuclear transport GO:0051169 72 0.011
Yeast
regulation of intracellular transport GO:0032386 64 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.010
single organism membrane organization GO:0044802 93 0.010
Yeast
defense response GO:0006952 300 0.010
Rat
gtp metabolic process GO:0046039 72 0.010
heterocycle catabolic process GO:0046700 166 0.010
Human Yeast Mouse Rat Worm
olfactory behavior GO:0042048 97 0.010
response to lipopolysaccharide GO:0032496 4 0.010

Hsc70-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.033