Drosophila melanogaster

26 known processes

Pitslre (Dmel_CG4268)

CG4268 gene product from transcript CG4268-RA

(Aliases: Gta,PITSLRE,Gat,cdk11,group 3,CG4268,Dmel\CG4268)

Pitslre biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.396
negative regulation of gene expression GO:0010629 387 0.215
negative regulation of transcription dna templated GO:0045892 237 0.112
regulation of rna splicing GO:0043484 69 0.104
organic substance catabolic process GO:1901575 308 0.100
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.095
appendage morphogenesis GO:0035107 397 0.086
regulation of cell morphogenesis GO:0022604 163 0.080
mrna metabolic process GO:0016071 124 0.080
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.079
negative regulation of biosynthetic process GO:0009890 277 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.073
organelle fission GO:0048285 340 0.072
Mouse
dendrite morphogenesis GO:0048813 199 0.069
taxis GO:0042330 304 0.069
negative regulation of cellular biosynthetic process GO:0031327 277 0.067
nucleobase containing compound catabolic process GO:0034655 165 0.057
organic cyclic compound catabolic process GO:1901361 168 0.054
negative regulation of rna biosynthetic process GO:1902679 240 0.052
transcription from rna polymerase ii promoter GO:0006366 368 0.051
imaginal disc derived appendage morphogenesis GO:0035114 395 0.051
regulation of mitotic cell cycle phase transition GO:1901990 130 0.051
regulation of cell cycle process GO:0010564 181 0.051
Mouse
mitotic cell cycle checkpoint GO:0007093 88 0.050
oocyte differentiation GO:0009994 145 0.050
regulation of molecular function GO:0065009 217 0.050
purine ribonucleoside metabolic process GO:0046128 127 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.049
germarium derived egg chamber formation GO:0007293 101 0.049
regulation of cell cycle phase transition GO:1901987 130 0.046
organonitrogen compound metabolic process GO:1901564 318 0.045
appendage development GO:0048736 401 0.043
purine ribonucleotide metabolic process GO:0009150 145 0.043
chemotaxis GO:0006935 249 0.043
cell cell signaling involved in cell fate commitment GO:0045168 210 0.042
negative regulation of nucleic acid templated transcription GO:1903507 240 0.042
negative regulation of rna metabolic process GO:0051253 251 0.042
glycosyl compound metabolic process GO:1901657 127 0.041
negative regulation of cellular metabolic process GO:0031324 382 0.041
small molecule metabolic process GO:0044281 305 0.041
response to light stimulus GO:0009416 124 0.041
purine containing compound catabolic process GO:0072523 112 0.040
axon guidance GO:0007411 233 0.040
dendrite development GO:0016358 204 0.040
heterocycle catabolic process GO:0046700 166 0.039
nucleoside phosphate catabolic process GO:1901292 110 0.039
purine containing compound metabolic process GO:0072521 155 0.039
cellular response to chemical stimulus GO:0070887 199 0.039
nuclear division GO:0000280 332 0.038
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.038
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.038
single organism catabolic process GO:0044712 228 0.038
ribonucleoside triphosphate catabolic process GO:0009203 108 0.038
body morphogenesis GO:0010171 2 0.037
regulation of catalytic activity GO:0050790 185 0.037
cellular catabolic process GO:0044248 372 0.037
negative regulation of cell cycle phase transition GO:1901988 103 0.037
dna damage checkpoint GO:0000077 78 0.036
regulation of mrna processing GO:0050684 71 0.036
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.036
negative regulation of cell cycle process GO:0010948 109 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
negative regulation of immune system process GO:0002683 50 0.034
purine nucleotide metabolic process GO:0006163 146 0.034
cell cycle phase transition GO:0044770 140 0.033
negative regulation of cell cycle GO:0045786 116 0.033
eye development GO:0001654 323 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
aromatic compound catabolic process GO:0019439 166 0.032
anatomical structure homeostasis GO:0060249 97 0.031
carbohydrate derivative catabolic process GO:1901136 118 0.031
cellular nitrogen compound catabolic process GO:0044270 165 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.030
regulation of mrna splicing via spliceosome GO:0048024 64 0.030
catabolic process GO:0009056 409 0.030
developmental growth GO:0048589 280 0.030
purine nucleoside metabolic process GO:0042278 127 0.029
ribonucleotide catabolic process GO:0009261 109 0.029
regulation of rho protein signal transduction GO:0035023 20 0.029
muscle organ development GO:0007517 127 0.028
purine ribonucleotide catabolic process GO:0009154 109 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
nucleoside catabolic process GO:0009164 112 0.028
cell cycle checkpoint GO:0000075 95 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.027
embryonic pattern specification GO:0009880 174 0.027
response to organic substance GO:0010033 284 0.027
vesicle mediated transport GO:0016192 381 0.027
macromolecule catabolic process GO:0009057 161 0.027
regulation of protein metabolic process GO:0051246 256 0.027
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.027
post embryonic appendage morphogenesis GO:0035120 385 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.026
protein complex biogenesis GO:0070271 201 0.026
nucleoside metabolic process GO:0009116 127 0.026
ribonucleoside catabolic process GO:0042454 112 0.026
muscle structure development GO:0061061 224 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
glycosyl compound catabolic process GO:1901658 112 0.025
wing disc morphogenesis GO:0007472 344 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
posttranscriptional regulation of gene expression GO:0010608 145 0.025
compound eye development GO:0048749 307 0.025
immune system process GO:0002376 347 0.025
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
ribose phosphate metabolic process GO:0019693 145 0.025
purine nucleoside triphosphate catabolic process GO:0009146 108 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
nucleotide metabolic process GO:0009117 161 0.024
positive regulation of cellular component biogenesis GO:0044089 80 0.023
regulation of organelle organization GO:0033043 196 0.023
Mouse
mitotic dna integrity checkpoint GO:0044774 75 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
mitotic nuclear division GO:0007067 213 0.023
Mouse
growth GO:0040007 359 0.023
Human
negative regulation of mitotic cell cycle GO:0045930 109 0.023
regulation of mrna metabolic process GO:1903311 72 0.023
Human
protein dna complex subunit organization GO:0071824 86 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
response to external biotic stimulus GO:0043207 293 0.022
neuron projection guidance GO:0097485 241 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
protein complex assembly GO:0006461 200 0.022
regulation of localization GO:0032879 275 0.022
regulation of immune system process GO:0002682 176 0.021
nucleotide catabolic process GO:0009166 109 0.021
cellular response to organic substance GO:0071310 132 0.021
mitotic cell cycle phase transition GO:0044772 138 0.021
mitotic dna damage checkpoint GO:0044773 74 0.021
ribonucleotide metabolic process GO:0009259 145 0.020
rna splicing GO:0008380 83 0.020
cellular protein modification process GO:0006464 438 0.020
Human
mrna splicing via spliceosome GO:0000398 73 0.020
ras protein signal transduction GO:0007265 88 0.020
macromolecular complex assembly GO:0065003 256 0.019
regulation of cell shape GO:0008360 113 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.019
regulation of translation GO:0006417 56 0.019
response to abiotic stimulus GO:0009628 341 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.019
organophosphate catabolic process GO:0046434 112 0.018
positive regulation of multi organism process GO:0043902 40 0.018
protein dna complex assembly GO:0065004 63 0.018
response to lipopolysaccharide GO:0032496 4 0.018
response to other organism GO:0051707 293 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
rna catabolic process GO:0006401 37 0.018
regulation of cell proliferation GO:0042127 163 0.018
maintenance of location GO:0051235 73 0.018
positive regulation of cell communication GO:0010647 250 0.018
segmentation GO:0035282 207 0.018
mitotic g2 dna damage checkpoint GO:0007095 69 0.018
adult behavior GO:0030534 137 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
lateral inhibition GO:0046331 206 0.017
mrna processing GO:0006397 104 0.017
Human
small gtpase mediated signal transduction GO:0007264 88 0.017
organophosphate metabolic process GO:0019637 195 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.017
blastoderm segmentation GO:0007350 159 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
regulation of growth GO:0040008 233 0.017
Human
rna transport GO:0050658 46 0.017
imaginal disc derived appendage development GO:0048737 399 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
dna templated transcription elongation GO:0006354 18 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
regionalization GO:0003002 416 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
defense response to other organism GO:0098542 225 0.016
response to radiation GO:0009314 155 0.016
multi organism behavior GO:0051705 175 0.016
phosphorylation GO:0016310 294 0.016
Human
dna metabolic process GO:0006259 227 0.016
rna splicing via transesterification reactions GO:0000375 73 0.015
cell maturation GO:0048469 144 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
negative regulation of developmental process GO:0051093 201 0.015
organic substance transport GO:0071702 257 0.015
positive regulation of signal transduction GO:0009967 223 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
chromatin silencing GO:0006342 76 0.015
regulation of purine nucleotide catabolic process GO:0033121 48 0.015
establishment of rna localization GO:0051236 47 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.015
nucleobase containing compound transport GO:0015931 56 0.014
chorion containing eggshell formation GO:0007304 105 0.014
ribonucleoside monophosphate metabolic process GO:0009161 51 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
rna processing GO:0006396 147 0.014
Human
regulation of cellular protein metabolic process GO:0032268 243 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
phagocytosis GO:0006909 215 0.014
alternative mrna splicing via spliceosome GO:0000380 60 0.014
detection of stimulus GO:0051606 156 0.014
response to biotic stimulus GO:0009607 294 0.014
regulation of hydrolase activity GO:0051336 97 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
nuclear transcribed mrna catabolic process GO:0000956 24 0.014
cell fate determination GO:0001709 91 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
actin filament organization GO:0007015 126 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
death GO:0016265 284 0.013
Mouse
gene silencing GO:0016458 138 0.013
sister chromatid segregation GO:0000819 92 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
cell division GO:0051301 248 0.013
Mouse
oocyte development GO:0048599 124 0.013
dna integrity checkpoint GO:0031570 81 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
response to oxidative stress GO:0006979 86 0.013
embryonic axis specification GO:0000578 107 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
Mouse Worm
innate immune response GO:0045087 144 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
oxoacid metabolic process GO:0043436 103 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
programmed cell death GO:0012501 257 0.012
Mouse
establishment of localization in cell GO:0051649 402 0.012
eggshell formation GO:0030703 105 0.012
extracellular matrix organization GO:0030198 32 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
regulation of cell development GO:0060284 215 0.012
camera type eye development GO:0043010 4 0.012
response to nutrient levels GO:0031667 114 0.012
intracellular signal transduction GO:0035556 300 0.012
regulation of response to biotic stimulus GO:0002831 63 0.011
regulation of meiosis GO:0040020 3 0.011
central nervous system development GO:0007417 201 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
chromosome organization GO:0051276 360 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
chromatin organization GO:0006325 207 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
autophagic cell death GO:0048102 83 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
translation GO:0006412 69 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
rna localization GO:0006403 115 0.011
defense response GO:0006952 300 0.011
aggressive behavior GO:0002118 63 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.011
multicellular organismal homeostasis GO:0048871 41 0.011
defense response to bacterium GO:0042742 178 0.011
mushroom body development GO:0016319 70 0.011
mitotic spindle organization GO:0007052 220 0.010
positive regulation of catabolic process GO:0009896 105 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
response to oxygen containing compound GO:1901700 200 0.010
immune response GO:0006955 246 0.010
organic acid metabolic process GO:0006082 103 0.010
jak stat cascade GO:0007259 49 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
germ line stem cell maintenance GO:0030718 50 0.010
gtp metabolic process GO:0046039 72 0.010
organelle assembly GO:0070925 198 0.010
nitrogen compound transport GO:0071705 85 0.010
compound eye morphogenesis GO:0001745 249 0.010
atp metabolic process GO:0046034 49 0.010
developmental maturation GO:0021700 172 0.010

Pitslre disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.010