Drosophila melanogaster

180 known processes

usp (Dmel_CG4380)

ultraspiracle

(Aliases: EG:22E5.1,DmUsp,DmUSP,dmUSP,CF1/USP,2C,cf1,Dmel\CG4380,Usp,XR2C,USP,NR2B4,CG4380,l(1)2Cf,l(1)usp,CF1,dUSP,CF1/Usp,Cf1)

usp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell maturation GO:0048469 144 0.993
blastoderm segmentation GO:0007350 159 0.991
Fly
mushroom body development GO:0016319 70 0.986
axis specification GO:0009798 167 0.979
Fly
eye morphogenesis GO:0048592 260 0.970
epithelium migration GO:0090132 148 0.964
oocyte construction GO:0007308 112 0.963
epithelial cell differentiation GO:0030855 322 0.957
developmental maturation GO:0021700 172 0.955
oocyte development GO:0048599 124 0.953
localization of cell GO:0051674 257 0.951
embryonic pattern specification GO:0009880 174 0.948
Fly
response to abiotic stimulus GO:0009628 341 0.946
tissue morphogenesis GO:0048729 297 0.925
cell motility GO:0048870 251 0.903
ovarian follicle cell migration GO:0007297 121 0.897
border follicle cell migration GO:0007298 113 0.888
digestive tract morphogenesis GO:0048546 127 0.883
photoreceptor cell differentiation GO:0046530 170 0.880
epithelial cell development GO:0002064 274 0.876
oocyte differentiation GO:0009994 145 0.854
stem cell division GO:0017145 69 0.851
Fly
ameboidal type cell migration GO:0001667 151 0.845
oocyte axis specification GO:0007309 108 0.840
regulation of actin filament based process GO:0032970 42 0.826
tube morphogenesis GO:0035239 191 0.799
epithelial cell migration GO:0010631 148 0.793
response to sterol GO:0036314 34 0.792
muscle structure development GO:0061061 224 0.782
regulation of actin cytoskeleton organization GO:0032956 42 0.781
negative regulation of developmental process GO:0051093 201 0.773
response to wounding GO:0009611 94 0.771
Fly
locomotory behavior GO:0007626 176 0.767
Fly
single organism cellular localization GO:1902580 180 0.763
eye development GO:0001654 323 0.762
eye photoreceptor cell differentiation GO:0001754 145 0.748
cell migration GO:0016477 238 0.742
cell adhesion GO:0007155 136 0.735
regulation of apoptotic process GO:0042981 130 0.724
sensory organ morphogenesis GO:0090596 260 0.715
compound eye photoreceptor cell differentiation GO:0001751 140 0.715
cellular ketone metabolic process GO:0042180 24 0.705
regulation of cell development GO:0060284 215 0.702
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.699
cell substrate adhesion GO:0031589 10 0.698
regulation of cellular localization GO:0060341 136 0.691
tissue migration GO:0090130 155 0.677
actomyosin structure organization GO:0031032 56 0.666
actin filament based process GO:0030029 220 0.664
negative regulation of cell differentiation GO:0045596 143 0.656
regulation of anatomical structure morphogenesis GO:0022603 242 0.648
Fly
nuclear division GO:0000280 332 0.644
morphogenesis of an epithelium GO:0002009 276 0.637
stem cell proliferation GO:0072089 88 0.636
Fly
single organism behavior GO:0044708 391 0.628
Fly
establishment of localization in cell GO:0051649 402 0.622
Fly
head development GO:0060322 135 0.604
cellular macromolecule localization GO:0070727 220 0.585
nucleotide metabolic process GO:0009117 161 0.569
photoreceptor cell development GO:0042461 96 0.565
segmentation GO:0035282 207 0.561
Fly
digestive system development GO:0055123 149 0.558
apoptotic process GO:0006915 159 0.555
programmed cell death GO:0012501 257 0.545
cellular response to organic cyclic compound GO:0071407 32 0.537
ion transport GO:0006811 145 0.536
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.532
muscle cell development GO:0055001 50 0.515
aging GO:0007568 143 0.513
multicellular organismal aging GO:0010259 140 0.502
brain development GO:0007420 120 0.500
compound eye morphogenesis GO:0001745 249 0.498
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.478
Fly
striated muscle cell development GO:0055002 50 0.468
organelle fission GO:0048285 340 0.468
regulation of actin filament length GO:0030832 27 0.467
anterior posterior pattern specification GO:0009952 136 0.466
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.463
Fly
positive regulation of developmental process GO:0051094 143 0.456
Fly
regulation of transport GO:0051049 181 0.441
eye photoreceptor cell development GO:0042462 81 0.429
camera type eye development GO:0043010 4 0.427
chemical homeostasis GO:0048878 92 0.425
regulation of cell adhesion GO:0030155 27 0.414
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.409
immune system process GO:0002376 347 0.408
Fly
regulation of mitotic cell cycle GO:0007346 190 0.407
body morphogenesis GO:0010171 2 0.407
urogenital system development GO:0001655 72 0.406
purine nucleoside catabolic process GO:0006152 112 0.400
regulation of programmed cell death GO:0043067 152 0.397
cell death GO:0008219 279 0.397
dendrite development GO:0016358 204 0.397
response to ecdysone GO:0035075 34 0.396
regulation of actin polymerization or depolymerization GO:0008064 27 0.392
ribonucleoside metabolic process GO:0009119 127 0.385
developmental growth GO:0048589 280 0.381
Fly
actin cytoskeleton organization GO:0030036 206 0.376
compound eye development GO:0048749 307 0.372
cellular response to organic substance GO:0071310 132 0.371
male gamete generation GO:0048232 201 0.366
growth GO:0040007 359 0.359
Fly
metal ion transport GO:0030001 74 0.353
maternal determination of anterior posterior axis embryo GO:0008358 74 0.349
regionalization GO:0003002 416 0.348
Fly
single organism intracellular transport GO:1902582 207 0.346
regulation of cytoskeleton organization GO:0051493 89 0.338
regulation of cell differentiation GO:0045595 302 0.337
Fly
dorsal ventral axis specification GO:0009950 66 0.321
regulation of organelle organization GO:0033043 196 0.318
open tracheal system development GO:0007424 204 0.316
regulation of protein transport GO:0051223 57 0.315
regulation of localization GO:0032879 275 0.314
Fly
response to endogenous stimulus GO:0009719 119 0.313
detection of stimulus GO:0051606 156 0.312
compound eye photoreceptor development GO:0042051 78 0.304
response to alcohol GO:0097305 95 0.304
cellular component assembly involved in morphogenesis GO:0010927 151 0.302
embryonic axis specification GO:0000578 107 0.298
Fly
oocyte dorsal ventral axis specification GO:0007310 34 0.295
cellular amine metabolic process GO:0044106 12 0.283
response to organic cyclic compound GO:0014070 89 0.280
secretion by cell GO:0032940 101 0.279
Fly
cellular response to oxygen containing compound GO:1901701 79 0.279
negative regulation of cell communication GO:0010648 223 0.275
actin polymerization or depolymerization GO:0008154 31 0.273
dorsal ventral pattern formation GO:0009953 133 0.271
renal system development GO:0072001 72 0.270
wing disc morphogenesis GO:0007472 344 0.267
Fly
muscle cell differentiation GO:0042692 103 0.266
embryo development ending in birth or egg hatching GO:0009792 152 0.261
negative regulation of response to stimulus GO:0048585 258 0.256
organic acid metabolic process GO:0006082 103 0.256
cellular response to ketone GO:1901655 17 0.255
ribose phosphate metabolic process GO:0019693 145 0.248
intracellular protein transport GO:0006886 104 0.239
digestive tract development GO:0048565 149 0.239
ovarian follicle cell development GO:0030707 248 0.237
lipid metabolic process GO:0006629 121 0.234
cholesterol homeostasis GO:0042632 3 0.233
anterior posterior axis specification embryo GO:0008595 103 0.232
Fly
homeostatic process GO:0042592 199 0.226
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.217
post embryonic appendage morphogenesis GO:0035120 385 0.215
Fly
positive regulation of axonogenesis GO:0050772 2 0.212
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.209
Fly
vesicle mediated transport GO:0016192 381 0.204
regulation of cellular amino acid metabolic process GO:0006521 0 0.204
sterol homeostasis GO:0055092 4 0.204
response to organonitrogen compound GO:0010243 75 0.200
neuron maturation GO:0042551 31 0.194
axonogenesis GO:0007409 290 0.190
Fly
camera type eye morphogenesis GO:0048593 2 0.190
negative regulation of signaling GO:0023057 219 0.186
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.186
glycosyl compound catabolic process GO:1901658 112 0.182
stem cell maintenance GO:0019827 67 0.177
negative regulation of neural precursor cell proliferation GO:2000178 27 0.177
regulation of cellular protein metabolic process GO:0032268 243 0.177
small molecule metabolic process GO:0044281 305 0.177
regulation of hormone levels GO:0010817 40 0.177
nucleobase containing small molecule metabolic process GO:0055086 174 0.176
cellular amino acid metabolic process GO:0006520 61 0.175
negative regulation of programmed cell death GO:0043069 72 0.174
inter male aggressive behavior GO:0002121 60 0.171
Fly
establishment of protein localization to plasma membrane GO:0090002 9 0.170
organonitrogen compound metabolic process GO:1901564 318 0.168
regulation of cellular amine metabolic process GO:0033238 3 0.167
regulation of protein localization GO:0032880 76 0.166
purine containing compound metabolic process GO:0072521 155 0.161
cell migration involved in gastrulation GO:0042074 9 0.160
biological adhesion GO:0022610 138 0.156
regulation of vesicle mediated transport GO:0060627 59 0.155
positive regulation of multicellular organismal process GO:0051240 143 0.154
Fly
actin filament polymerization GO:0030041 27 0.154
nucleoside triphosphate catabolic process GO:0009143 108 0.152
skeletal muscle organ development GO:0060538 48 0.149
development of primary sexual characteristics GO:0045137 50 0.148
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.147
regulation of secretion by cell GO:1903530 39 0.147
death GO:0016265 284 0.145
regulation of intracellular protein transport GO:0033157 46 0.143
carboxylic acid metabolic process GO:0019752 92 0.143
carbohydrate derivative catabolic process GO:1901136 118 0.143
gastrulation GO:0007369 70 0.142
circadian rhythm GO:0007623 105 0.139
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.139
Fly
cell division GO:0051301 248 0.138
Fly
rhabdomere development GO:0042052 38 0.138
response to lipid GO:0033993 38 0.135
learning or memory GO:0007611 141 0.135
positive regulation of programmed cell death GO:0043068 62 0.133
negative regulation of cellular biosynthetic process GO:0031327 277 0.132
Fly
protein transport GO:0015031 155 0.132
actin filament organization GO:0007015 126 0.130
pupal development GO:0035209 11 0.127
stem cell differentiation GO:0048863 117 0.127
regulation of multicellular organismal development GO:2000026 414 0.125
Fly
cytoplasmic transport GO:0016482 130 0.124
positive regulation of developmental growth GO:0048639 62 0.124
Fly
cell type specific apoptotic process GO:0097285 38 0.123
reproductive structure development GO:0048608 74 0.121
maintenance of protein location GO:0045185 28 0.121
glycosyl compound metabolic process GO:1901657 127 0.121
regulation of cell morphogenesis GO:0022604 163 0.120
Fly
appendage morphogenesis GO:0035107 397 0.119
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.119
gastrulation with mouth forming first GO:0001703 36 0.118
response to nitrogen compound GO:1901698 90 0.116
regulation of cell cell adhesion GO:0022407 21 0.111
regulation of reproductive process GO:2000241 54 0.108
larval development GO:0002164 104 0.107
regulation of cellular component biogenesis GO:0044087 201 0.105
tripartite regional subdivision GO:0007351 103 0.105
Fly
muscle organ development GO:0007517 127 0.105
catabolic process GO:0009056 409 0.104
nucleoside catabolic process GO:0009164 112 0.104
determination of adult lifespan GO:0008340 137 0.104
negative regulation of cell adhesion GO:0007162 9 0.103
multicellular organismal homeostasis GO:0048871 41 0.102
regulation of cell substrate adhesion GO:0010810 2 0.101
spermatogenesis GO:0007283 200 0.101
nucleoside phosphate catabolic process GO:1901292 110 0.101
sleep GO:0030431 49 0.100
lipid catabolic process GO:0016042 21 0.100
intracellular transport GO:0046907 228 0.099
oxoacid metabolic process GO:0043436 103 0.099
cation transport GO:0006812 110 0.098
protein localization to plasma membrane GO:0072659 13 0.098
cell matrix adhesion GO:0007160 6 0.096
carbohydrate derivative metabolic process GO:1901135 217 0.096
regulation of cellular ketone metabolic process GO:0010565 3 0.095
purine ribonucleotide catabolic process GO:0009154 109 0.095
dendrite morphogenesis GO:0048813 199 0.094
negative regulation of signal transduction GO:0009968 206 0.094
negative regulation of gene expression GO:0010629 387 0.091
Fly
organic hydroxy compound metabolic process GO:1901615 83 0.089
enzyme linked receptor protein signaling pathway GO:0007167 179 0.089
Fly
response to peptide hormone GO:0043434 29 0.089
convergent extension involved in gastrulation GO:0060027 2 0.088
negative regulation of apoptotic process GO:0043066 63 0.088
response to oxygen containing compound GO:1901700 200 0.088
negative regulation of transcription dna templated GO:0045892 237 0.087
Fly
regulation of cellular catabolic process GO:0031329 157 0.087
sex differentiation GO:0007548 81 0.086
cellular response to endogenous stimulus GO:0071495 80 0.086
negative regulation of cell death GO:0060548 81 0.086
reproductive system development GO:0061458 74 0.085
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.085
detection of external stimulus GO:0009581 66 0.085
gonad development GO:0008406 50 0.085
oocyte anterior posterior axis specification GO:0007314 72 0.085
regulation of cellular component movement GO:0051270 42 0.082
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.082
Fly
oocyte microtubule cytoskeleton organization GO:0016325 35 0.081
neural precursor cell proliferation GO:0061351 75 0.081
Fly
kidney morphogenesis GO:0060993 3 0.080
negative regulation of cell cell adhesion GO:0022408 8 0.079
cellular homeostasis GO:0019725 80 0.079
organophosphate metabolic process GO:0019637 195 0.079
negative regulation of biosynthetic process GO:0009890 277 0.076
Fly
regulation of cell death GO:0010941 173 0.075
cytokinesis GO:0000910 90 0.074
regulation of metal ion transport GO:0010959 15 0.074
negative regulation of neuroblast proliferation GO:0007406 27 0.074
protein localization GO:0008104 284 0.073
multicellular organismal reproductive behavior GO:0033057 110 0.072
myofibril assembly GO:0030239 36 0.071
stress fiber assembly GO:0043149 6 0.071
mitotic spindle organization GO:0007052 220 0.071
kidney development GO:0001822 3 0.071
neuron remodeling GO:0016322 29 0.070
regulation of stem cell proliferation GO:0072091 40 0.070
negative regulation of rna metabolic process GO:0051253 251 0.069
Fly
response to hypoxia GO:0001666 53 0.069
intracellular mrna localization GO:0008298 66 0.069
cellular catabolic process GO:0044248 372 0.069
phagocytosis GO:0006909 215 0.068
cell junction organization GO:0034330 57 0.068
regulation of cell cycle process GO:0010564 181 0.068
convergent extension GO:0060026 2 0.067
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.066
Fly
male mating behavior GO:0060179 70 0.066
regulation of ion transport GO:0043269 39 0.066
proteolysis GO:0006508 192 0.066
positive regulation of cell death GO:0010942 69 0.066
purine nucleotide catabolic process GO:0006195 109 0.064
cellular component disassembly GO:0022411 46 0.064
regulation of actin filament polymerization GO:0030833 25 0.063
retina development in camera type eye GO:0060041 4 0.062
establishment of protein localization to membrane GO:0090150 11 0.062
positive regulation of phosphate metabolic process GO:0045937 139 0.061
macromolecular complex assembly GO:0065003 256 0.060
response to decreased oxygen levels GO:0036293 58 0.060
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.060
positive regulation of apoptotic process GO:0043065 47 0.060
imaginal disc derived appendage morphogenesis GO:0035114 395 0.059
Fly
neurological system process GO:0050877 358 0.059
cellular chemical homeostasis GO:0055082 40 0.059
ribonucleotide catabolic process GO:0009261 109 0.059
response to inorganic substance GO:0010035 44 0.058
peptidyl amino acid modification GO:0018193 105 0.058
respiratory system development GO:0060541 213 0.058
response to ketone GO:1901654 34 0.058
organic substance transport GO:0071702 257 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.056
positive regulation of dendrite morphogenesis GO:0050775 9 0.055
regulation of secretion GO:0051046 44 0.054
positive regulation of cell projection organization GO:0031346 29 0.054
Fly
striated muscle cell differentiation GO:0051146 90 0.054
purine nucleoside metabolic process GO:0042278 127 0.053
multi organism reproductive behavior GO:0044705 121 0.052
regulation of cell cycle GO:0051726 291 0.052
Fly
taxis GO:0042330 304 0.052
Fly
germ cell migration GO:0008354 43 0.052
pole plasm oskar mrna localization GO:0045451 46 0.051
nucleoside metabolic process GO:0009116 127 0.051
regulation of neural precursor cell proliferation GO:2000177 35 0.051
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.051
detection of light stimulus GO:0009583 58 0.051
regulation of intracellular transport GO:0032386 64 0.050
negative regulation of cellular component organization GO:0051129 108 0.050
maintenance of protein location in cell GO:0032507 26 0.050
organic substance catabolic process GO:1901575 308 0.050
nuclear export GO:0051168 24 0.049
negative regulation of molecular function GO:0044092 51 0.049
endocytosis GO:0006897 310 0.049
organophosphate catabolic process GO:0046434 112 0.049
positive regulation of cell differentiation GO:0045597 64 0.048
Fly
positive regulation of secretion GO:0051047 22 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
Fly
amine metabolic process GO:0009308 12 0.048
purine nucleotide metabolic process GO:0006163 146 0.048
humoral immune response GO:0006959 117 0.048
cognition GO:0050890 141 0.048
aromatic compound catabolic process GO:0019439 166 0.048
hindgut development GO:0061525 58 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.046
cellular response to nitrogen compound GO:1901699 51 0.046
nucleoside phosphate metabolic process GO:0006753 162 0.046
positive regulation of organelle organization GO:0010638 65 0.045
regulation of cytoplasmic transport GO:1903649 47 0.045
cell fate determination GO:0001709 91 0.044
secretion GO:0046903 109 0.044
Fly
nucleotide catabolic process GO:0009166 109 0.044
actin filament bundle organization GO:0061572 28 0.044
nuclear import GO:0051170 51 0.044
protein complex assembly GO:0006461 200 0.043
regulation of lipid metabolic process GO:0019216 15 0.043
regulation of embryonic development GO:0045995 68 0.043
maintenance of location GO:0051235 73 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.042
negative regulation of cell development GO:0010721 62 0.042
regulation of establishment of protein localization to plasma membrane GO:0090003 7 0.042
nuclear transport GO:0051169 72 0.042
mitotic nuclear division GO:0007067 213 0.042
cellular macromolecular complex assembly GO:0034622 153 0.042
circadian behavior GO:0048512 76 0.041
Fly
regulation of axon extension GO:0030516 8 0.041
Fly
nitrogen compound transport GO:0071705 85 0.040
regulation of cell matrix adhesion GO:0001952 1 0.040
positive regulation of cellular biosynthetic process GO:0031328 316 0.040
receptor mediated endocytosis GO:0006898 21 0.040
cellular response to chemical stimulus GO:0070887 199 0.040
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.040
protein localization to organelle GO:0033365 82 0.040
collateral sprouting GO:0048668 3 0.039
muscle tissue development GO:0060537 30 0.039
phosphatidylinositol mediated signaling GO:0048015 4 0.039
regulation of immune system process GO:0002682 176 0.039
Fly
regulation of nervous system development GO:0051960 248 0.039
Fly
single organism catabolic process GO:0044712 228 0.039
response to organic substance GO:0010033 284 0.039
response to monosaccharide GO:0034284 4 0.039
regulation of lamellipodium organization GO:1902743 15 0.038
actin filament based movement GO:0030048 26 0.038
regulation of locomotion GO:0040012 42 0.038
Fly
regulation of cellular component size GO:0032535 98 0.037
Fly
regulation of response to external stimulus GO:0032101 115 0.037
Fly
heterocycle catabolic process GO:0046700 166 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.037
cytoplasm organization GO:0007028 64 0.037
positive regulation of secretion by cell GO:1903532 20 0.037
regulation of hydrolase activity GO:0051336 97 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
ribonucleoside triphosphate catabolic process GO:0009203 108 0.035
ion homeostasis GO:0050801 55 0.035
cellular response to dna damage stimulus GO:0006974 223 0.035
cellular response to peptide GO:1901653 28 0.035
regulation of protein depolymerization GO:1901879 27 0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.034
purine ribonucleotide metabolic process GO:0009150 145 0.033
steroid metabolic process GO:0008202 20 0.033
regulation of synaptic plasticity GO:0048167 14 0.033
intracellular receptor signaling pathway GO:0030522 19 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.033
organic cyclic compound catabolic process GO:1901361 168 0.033
negative regulation of sequestering of calcium ion GO:0051283 2 0.033
response to nutrient levels GO:0031667 114 0.033
ribonucleoside triphosphate metabolic process GO:0009199 119 0.032
regulation of nucleocytoplasmic transport GO:0046822 35 0.032
regulation of developmental growth GO:0048638 174 0.032
Fly
response to temperature stimulus GO:0009266 106 0.032
response to oxygen levels GO:0070482 59 0.032
ecdysone receptor mediated signaling pathway GO:0035076 11 0.032
extrinsic apoptotic signaling pathway GO:0097191 1 0.032
positive regulation of cell migration GO:0030335 2 0.032
antimicrobial humoral response GO:0019730 99 0.031
anterior posterior axis specification GO:0009948 109 0.031
Fly
positive regulation of protein transport GO:0051222 37 0.031
rhythmic process GO:0048511 106 0.031
Fly
cellular response to abiotic stimulus GO:0071214 58 0.031
cellular protein complex assembly GO:0043623 71 0.031
regulation of cell shape GO:0008360 113 0.030
organonitrogen compound catabolic process GO:1901565 128 0.030
connective tissue development GO:0061448 3 0.030
pole plasm assembly GO:0007315 61 0.030
larval behavior GO:0030537 42 0.030
response to radiation GO:0009314 155 0.030
regulation of cell motility GO:2000145 23 0.030
regulation of hemocyte proliferation GO:0035206 37 0.030
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
regulation of anatomical structure size GO:0090066 163 0.029
Fly
organelle assembly GO:0070925 198 0.029
regulation of dna binding GO:0051101 10 0.029
establishment of protein localization GO:0045184 163 0.029
actin filament depolymerization GO:0030042 5 0.029
cellular response to ecdysone GO:0071390 17 0.028
regulation of cell division GO:0051302 72 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
mating GO:0007618 120 0.028
regulation of circadian rhythm GO:0042752 49 0.028
protein targeting GO:0006605 64 0.028
regulation of catalytic activity GO:0050790 185 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
Fly
regulation of protein localization to plasma membrane GO:1903076 7 0.027
guanosine containing compound catabolic process GO:1901069 74 0.027
positive regulation of cell motility GO:2000147 3 0.027
tissue homeostasis GO:0001894 36 0.027
rho protein signal transduction GO:0007266 14 0.027
plasma membrane organization GO:0007009 26 0.027
carbohydrate metabolic process GO:0005975 82 0.027
response to virus GO:0009615 28 0.026
gtp catabolic process GO:0006184 72 0.026
dna integrity checkpoint GO:0031570 81 0.026
regulation of purine nucleotide metabolic process GO:1900542 62 0.026
apoptotic signaling pathway GO:0097190 27 0.026
regulation of molecular function GO:0065009 217 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
stem cell development GO:0048864 79 0.025
ribonucleotide metabolic process GO:0009259 145 0.025
regulation of establishment of protein localization GO:0070201 61 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
regulation of behavior GO:0050795 75 0.025
Fly
morphogenesis of a polarized epithelium GO:0001738 93 0.025
salivary gland development GO:0007431 162 0.025
regulation of peptide hormone secretion GO:0090276 5 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
negative regulation of cellular protein metabolic process GO:0032269 85 0.025
synaptic transmission GO:0007268 288 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
Fly
regulation of blood circulation GO:1903522 21 0.024
single organism carbohydrate metabolic process GO:0044723 72 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.024
positive regulation of signaling GO:0023056 243 0.024
central nervous system development GO:0007417 201 0.024
single organism membrane organization GO:0044802 93 0.024
regulation of proteolysis GO:0030162 87 0.023
phosphorylation GO:0016310 294 0.023
neuroblast proliferation GO:0007405 74 0.023
Fly
regulation of neuroblast proliferation GO:1902692 34 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
immune system development GO:0002520 57 0.022
retina morphogenesis in camera type eye GO:0060042 2 0.022
olfactory behavior GO:0042048 97 0.022
cellular protein localization GO:0034613 160 0.022
nucleocytoplasmic transport GO:0006913 72 0.022
regulation of actin filament depolymerization GO:0030834 3 0.022
nucleoside monophosphate catabolic process GO:0009125 39 0.022
developmental programmed cell death GO:0010623 138 0.021
exocrine system development GO:0035272 162 0.021
macromolecule catabolic process GO:0009057 161 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
regulation of synaptic transmission GO:0050804 69 0.021
maintenance of location in cell GO:0051651 28 0.021
negative regulation of peptide secretion GO:0002792 1 0.021
axon guidance GO:0007411 233 0.021
Fly
rhythmic behavior GO:0007622 76 0.021
Fly
regulation of protein metabolic process GO:0051246 256 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.020
gland morphogenesis GO:0022612 145 0.020
lipid localization GO:0010876 54 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
atp metabolic process GO:0046034 49 0.020
golgi to plasma membrane transport GO:0006893 8 0.020
positive regulation of transport GO:0051050 92 0.020
mitotic cell cycle phase transition GO:0044772 138 0.019

usp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.020