Drosophila melanogaster

10 known processes

Hsp23 (Dmel_CG4463)

Heat shock protein 23

(Aliases: CG4463,23,hsp23,Hsp-23,HSP23/IAP,DmHsp23,HSP23,hsp23/22,hsp 23,hsp 23K,Dmel\CG4463,small hsp locus 67B,hsp 22K)

Hsp23 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 401 0.655
Fly
negative regulation of reactive oxygen species metabolic process GO:2000378 1 0.622
Rat
imaginal disc derived appendage development GO:0048737 399 0.548
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.546
Fly
wing disc morphogenesis GO:0007472 344 0.539
Fly
response to temperature stimulus GO:0009266 106 0.459
response to heat GO:0009408 63 0.370
Rat Fly
post embryonic appendage morphogenesis GO:0035120 385 0.327
Fly
response to hydrogen peroxide GO:0042542 11 0.326
Mouse Rat
appendage morphogenesis GO:0035107 397 0.317
Fly
apoptotic process involved in morphogenesis GO:0060561 3 0.294
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.253
Fly
glutathione metabolic process GO:0006749 37 0.209
defense response to bacterium GO:0042742 178 0.182
Fly
growth GO:0040007 359 0.179
Rat
defense response GO:0006952 300 0.168
Fly
response to fungus GO:0009620 50 0.161
Fly
epithelial cell differentiation GO:0030855 322 0.153
response to endogenous stimulus GO:0009719 119 0.146
Rat
response to bacterium GO:0009617 198 0.119
Fly
cellular response to ionizing radiation GO:0071479 15 0.119
heat shock mediated polytene chromosome puffing GO:0035080 7 0.115
response to other organism GO:0051707 293 0.112
Fly
cellular amide metabolic process GO:0043603 80 0.108
negative regulation of cellular metabolic process GO:0031324 382 0.107
Mouse Rat
defense response to other organism GO:0098542 225 0.106
Fly
response to extracellular stimulus GO:0009991 116 0.102
Fly
regulation of growth GO:0040008 233 0.097
Rat
cellular modified amino acid metabolic process GO:0006575 45 0.089
response to cold GO:0009409 13 0.088
negative regulation of biosynthetic process GO:0009890 277 0.086
response to abiotic stimulus GO:0009628 341 0.083
regulation of protein metabolic process GO:0051246 256 0.079
Mouse
response to reactive oxygen species GO:0000302 24 0.076
Mouse Rat
macromolecular complex assembly GO:0065003 256 0.075
Human Mouse
behavioral response to starvation GO:0042595 6 0.075
Fly
cold acclimation GO:0009631 8 0.074
chemotaxis GO:0006935 249 0.071
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.069
Mouse
cellular protein complex assembly GO:0043623 71 0.067
Mouse
intracellular signal transduction GO:0035556 300 0.067
Mouse Rat
peptide metabolic process GO:0006518 80 0.067
establishment of localization in cell GO:0051649 402 0.065
Human
taxis GO:0042330 304 0.065
actin cytoskeleton organization GO:0030036 206 0.063
camera type eye morphogenesis GO:0048593 2 0.063
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.062
camera type eye development GO:0043010 4 0.061
Mouse
sensory perception GO:0007600 196 0.061
Human
cellular response to gamma radiation GO:0071480 10 0.059
stress activated mapk cascade GO:0051403 52 0.058
Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.057
Mouse
regulation of response to external stimulus GO:0032101 115 0.056
intracellular transport GO:0046907 228 0.056
Human
response to nutrient levels GO:0031667 114 0.056
Fly
negative regulation of response to stimulus GO:0048585 258 0.055
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.055
transcription from rna polymerase ii promoter GO:0006366 368 0.055
regulation of cell death GO:0010941 173 0.055
Human Mouse Rat
negative regulation of endopeptidase activity GO:0010951 11 0.054
Mouse
detection of abiotic stimulus GO:0009582 66 0.054
positive regulation of cell motility GO:2000147 3 0.054
multicellular organismal aging GO:0010259 140 0.054
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.054
death GO:0016265 284 0.054
Human Mouse Rat
regulation of cellular protein metabolic process GO:0032268 243 0.053
Mouse
phosphorylation GO:0016310 294 0.053
Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.052
response to external biotic stimulus GO:0043207 293 0.051
Fly
response to radiation GO:0009314 155 0.051
regulation of cell growth GO:0001558 43 0.051
Rat
regulation of cysteine type endopeptidase activity GO:2000116 27 0.050
Mouse
regulation of programmed cell death GO:0043067 152 0.049
Human Mouse Rat
sulfur compound metabolic process GO:0006790 59 0.048
epithelial cell development GO:0002064 274 0.047
regulation of intracellular signal transduction GO:1902531 236 0.047
Mouse
cell growth GO:0016049 108 0.047
Rat
negative regulation of cellular response to oxidative stress GO:1900408 1 0.046
Mouse
response to biotic stimulus GO:0009607 294 0.045
Fly
actin filament based process GO:0030029 220 0.045
negative regulation of cell death GO:0060548 81 0.045
Human Mouse Rat
aging GO:0007568 143 0.043
Rat Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.043
sensory perception of light stimulus GO:0050953 12 0.043
Human
regulation of behavior GO:0050795 75 0.043
translation GO:0006412 69 0.042
apoptotic process GO:0006915 159 0.042
Human Mouse Rat
cellular response to radiation GO:0071478 52 0.041
programmed cell death GO:0012501 257 0.041
Human Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.041
regulation of response to stress GO:0080134 200 0.041
Mouse
positive regulation of response to external stimulus GO:0032103 44 0.041
detection of stimulus GO:0051606 156 0.041
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.041
Mouse
defense response to fungus GO:0050832 48 0.040
Fly
regulation of response to oxidative stress GO:1902882 4 0.040
Mouse
regulation of apoptotic process GO:0042981 130 0.040
Human Mouse Rat
negative regulation of cell communication GO:0010648 223 0.040
Mouse
regulation of multicellular organismal development GO:2000026 414 0.039
eye morphogenesis GO:0048592 260 0.039
response to ionizing radiation GO:0010212 32 0.038
cellular protein modification process GO:0006464 438 0.038
Mouse
negative regulation of peptidase activity GO:0010466 11 0.037
Mouse
positive regulation of cell migration GO:0030335 2 0.037
cellular response to heat GO:0034605 24 0.037
rna localization GO:0006403 115 0.037
detection of external stimulus GO:0009581 66 0.037
muscle system process GO:0003012 21 0.036
Rat
protein phosphorylation GO:0006468 169 0.036
Mouse
signal transduction by phosphorylation GO:0023014 107 0.035
Rat
protein complex assembly GO:0006461 200 0.035
Human Mouse
regulation of intracellular transport GO:0032386 64 0.034
Human
oxoacid metabolic process GO:0043436 103 0.033
negative regulation of apoptotic process GO:0043066 63 0.033
Human Mouse Rat
response to organic cyclic compound GO:0014070 89 0.033
Rat
dna damage checkpoint GO:0000077 78 0.033
tissue homeostasis GO:0001894 36 0.032
response to organic substance GO:0010033 284 0.032
Rat
cellular amino acid metabolic process GO:0006520 61 0.032
regulation of translation GO:0006417 56 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
Mouse
negative regulation of growth GO:0045926 84 0.032
Rat
response to oxygen containing compound GO:1901700 200 0.031
Mouse Rat
regulation of cellular response to stress GO:0080135 89 0.031
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.031
reactive oxygen species metabolic process GO:0072593 22 0.031
Rat
response to hypoxia GO:0001666 53 0.030
protein complex biogenesis GO:0070271 201 0.030
Human Mouse
muscle organ development GO:0007517 127 0.030
Mouse
microtubule polymerization or depolymerization GO:0031109 39 0.030
Rat
negative regulation of gene expression GO:0010629 387 0.030
Mouse
negative regulation of response to oxidative stress GO:1902883 1 0.029
Mouse
regulation of system process GO:0044057 36 0.029
Rat
muscle structure development GO:0061061 224 0.029
Mouse
regulation of transport GO:0051049 181 0.029
Human
response to oxidative stress GO:0006979 86 0.029
Mouse Rat Fly
negative regulation of transcription dna templated GO:0045892 237 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.028
stress activated protein kinase signaling cascade GO:0031098 55 0.028
Rat
regulation of cell differentiation GO:0045595 302 0.028
biological adhesion GO:0022610 138 0.028
response to alcohol GO:0097305 95 0.027
Rat
autophagy GO:0006914 108 0.027
cell cycle checkpoint GO:0000075 95 0.027
response to light stimulus GO:0009416 124 0.027
spermatogenesis GO:0007283 200 0.027
muscle contraction GO:0006936 13 0.027
Rat
male courtship behavior GO:0008049 63 0.026
rna processing GO:0006396 147 0.026
regulation of molecular function GO:0065009 217 0.026
Mouse
actin filament organization GO:0007015 126 0.026
negative regulation of signal transduction GO:0009968 206 0.025
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
visual perception GO:0007601 9 0.025
Human
response to nitrogen compound GO:1901698 90 0.025
anatomical structure homeostasis GO:0060249 97 0.025
response to starvation GO:0042594 97 0.024
Fly
mitotic dna integrity checkpoint GO:0044774 75 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
homeostatic process GO:0042592 199 0.023
multicellular organismal homeostasis GO:0048871 41 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
Mouse
determination of adult lifespan GO:0008340 137 0.023
Fly
negative regulation of programmed cell death GO:0043069 72 0.023
Human Mouse Rat
sensory organ morphogenesis GO:0090596 260 0.023
organic acid metabolic process GO:0006082 103 0.023
regulation of cell cycle process GO:0010564 181 0.023
posttranscriptional regulation of gene expression GO:0010608 145 0.022
g2 dna damage checkpoint GO:0031572 69 0.022
cell cycle phase transition GO:0044770 140 0.022
regulation of chemotaxis GO:0050920 12 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
Mouse
response to wounding GO:0009611 94 0.022
mitotic g2 dna damage checkpoint GO:0007095 69 0.022
jak stat cascade GO:0007259 49 0.021
mitotic g2 m transition checkpoint GO:0044818 70 0.021
cellular response to organic substance GO:0071310 132 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
Mouse
neurological system process GO:0050877 358 0.020
Human
regulation of reactive oxygen species metabolic process GO:2000377 8 0.020
Rat
regulation of epithelial cell migration GO:0010632 12 0.020
regulation of localization GO:0032879 275 0.020
Human
cellular response to oxidative stress GO:0034599 28 0.020
Mouse
polytene chromosome puffing GO:0035079 7 0.019
negative regulation of transferase activity GO:0051348 18 0.019
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
ameboidal type cell migration GO:0001667 151 0.019
regulation of defense response GO:0031347 102 0.019
amine metabolic process GO:0009308 12 0.019
response to gamma radiation GO:0010332 17 0.019
regionalization GO:0003002 416 0.019
mitotic nuclear division GO:0007067 213 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.018
cell maturation GO:0048469 144 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
negative regulation of cell cycle GO:0045786 116 0.018
positive regulation of signal transduction GO:0009967 223 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
cellular response to abiotic stimulus GO:0071214 58 0.018
single organism behavior GO:0044708 391 0.018
negative regulation of intracellular signal transduction GO:1902532 57 0.018
Mouse
cell adhesion GO:0007155 136 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
Mouse
regulation of transferase activity GO:0051338 58 0.017
Mouse
regulation of proteolysis GO:0030162 87 0.017
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.017
small molecule metabolic process GO:0044281 305 0.017
synapse organization GO:0050808 196 0.017
negative regulation of kinase activity GO:0033673 16 0.017
Mouse
pole plasm rna localization GO:0007316 52 0.017
dna integrity checkpoint GO:0031570 81 0.017
spermatid development GO:0007286 98 0.017
positive regulation of developmental process GO:0051094 143 0.017
positive regulation of signaling GO:0023056 243 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
single organismal cell cell adhesion GO:0016337 45 0.016
cellular amine metabolic process GO:0044106 12 0.016
oocyte axis specification GO:0007309 108 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
negative regulation of signaling GO:0023057 219 0.016
Mouse
developmental programmed cell death GO:0010623 138 0.016
Mouse
carboxylic acid metabolic process GO:0019752 92 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
mitotic dna damage checkpoint GO:0044773 74 0.016
somatic muscle development GO:0007525 66 0.016
histolysis GO:0007559 102 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
regulation of hydrolase activity GO:0051336 97 0.016
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.016
body morphogenesis GO:0010171 2 0.016
positive regulation of multi organism process GO:0043902 40 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
Mouse
embryonic morphogenesis GO:0048598 206 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
single organism cell adhesion GO:0098602 47 0.016
regulation of catalytic activity GO:0050790 185 0.015
Mouse
larval development GO:0002164 104 0.015
open tracheal system development GO:0007424 204 0.015
regulation of protein modification process GO:0031399 112 0.015
Mouse
mitotic cell cycle phase transition GO:0044772 138 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
Mouse
forebrain development GO:0030900 2 0.015
dorsal ventral pattern formation GO:0009953 133 0.014
negative regulation of phosphate metabolic process GO:0045936 45 0.014
Mouse
negative regulation of cell differentiation GO:0045596 143 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
embryonic pattern specification GO:0009880 174 0.014
response to lipopolysaccharide GO:0032496 4 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.014
cell death GO:0008219 279 0.014
Human Mouse Rat
positive regulation of multicellular organismal process GO:0051240 143 0.014
Mouse
response to organonitrogen compound GO:0010243 75 0.014
proteolysis GO:0006508 192 0.014
Mouse
response to methotrexate GO:0031427 11 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
axis specification GO:0009798 167 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
spinal cord development GO:0021510 1 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
wound healing GO:0042060 75 0.013
positive regulation of chemotaxis GO:0050921 2 0.013
oocyte differentiation GO:0009994 145 0.013
response to virus GO:0009615 28 0.013
regulation of cell cycle GO:0051726 291 0.013
detection of light stimulus GO:0009583 58 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
salivary gland histolysis GO:0035070 88 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
mapk cascade GO:0000165 107 0.013
Rat
limb development GO:0060173 1 0.012
cytoplasmic transport GO:0016482 130 0.012
regulation of multi organism process GO:0043900 131 0.012
chromosome organization GO:0051276 360 0.012
regulation of autophagy GO:0010506 62 0.012
protein processing GO:0016485 68 0.012
Mouse
negative regulation of mitotic cell cycle GO:0045930 109 0.012
response to uv GO:0009411 24 0.012
leg disc morphogenesis GO:0007478 80 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
organic substance transport GO:0071702 257 0.012
negative regulation of defense response GO:0031348 35 0.012
regulation of cell development GO:0060284 215 0.012
compound eye development GO:0048749 307 0.012
phosphatidylethanolamine metabolic process GO:0046337 1 0.012
tissue death GO:0016271 102 0.012
mushroom body development GO:0016319 70 0.012
regulation of phosphorylation GO:0042325 147 0.012
Mouse
pigment biosynthetic process GO:0046148 36 0.012
limb morphogenesis GO:0035108 1 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
response to organophosphorus GO:0046683 2 0.012
developmental maturation GO:0021700 172 0.011
cellular biogenic amine catabolic process GO:0042402 1 0.011
positive regulation of cell death GO:0010942 69 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
epithelium migration GO:0090132 148 0.011
macromolecule catabolic process GO:0009057 161 0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 2 0.011
Mouse
memory GO:0007613 94 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
cell cycle arrest GO:0007050 4 0.011
embryonic organ development GO:0048568 50 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
Mouse
positive regulation of cell communication GO:0010647 250 0.011
gtp metabolic process GO:0046039 72 0.011
positive regulation of melanization defense response GO:0035008 1 0.011
negative regulation of molecular function GO:0044092 51 0.011
Mouse
innate immune response GO:0045087 144 0.011
apoptotic signaling pathway GO:0097190 27 0.011
Mouse
catabolic process GO:0009056 409 0.011
pole plasm oskar mrna localization GO:0045451 46 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
response to growth factor GO:0070848 31 0.011
regulation of body fluid levels GO:0050878 14 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
response to endoplasmic reticulum stress GO:0034976 28 0.010
phagocytosis GO:0006909 215 0.010
regulation of defense response to bacterium GO:1900424 30 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
adult behavior GO:0030534 137 0.010
negative regulation of developmental process GO:0051093 201 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
salivary gland morphogenesis GO:0007435 145 0.010

Hsp23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
neuropathy DOID:870 0 0.529
Human
charcot marie tooth disease DOID:10595 0 0.529
Human
nervous system disease DOID:863 0 0.529
Human
disease of anatomical entity DOID:7 0 0.529
Human
charcot marie tooth disease type 2 DOID:0050539 0 0.529
Human
neuromuscular disease DOID:440 0 0.529
Human
central nervous system disease DOID:331 0 0.358
Human
motor neuron disease DOID:231 0 0.358
Human
neurodegenerative disease DOID:1289 0 0.358
Human
musculoskeletal system disease DOID:17 0 0.103
cardiovascular system disease DOID:1287 0 0.103
muscle tissue disease DOID:66 0 0.098
muscular disease DOID:0080000 0 0.098
cardiomyopathy DOID:0050700 0 0.067
heart disease DOID:114 0 0.067
intrinsic cardiomyopathy DOID:0060036 0 0.067
myopathy DOID:423 0 0.067
eye disease DOID:5614 0 0.066
eye and adnexa disease DOID:1492 0 0.066
sensory system disease DOID:0050155 0 0.066
dilated cardiomyopathy DOID:12930 0 0.025
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012