Drosophila melanogaster

218 known processes

XNP (Dmel_CG4548)

CG4548 gene product from transcript CG4548-RA

(Aliases: xnp,EP(3)0635,EP635,dATRX,Dmel\CG4548,dXNP,CG4548,xnp/atr-x,DATR-X,DATRX,ATR-X/XNP)

XNP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of gene expression epigenetic GO:0045814 77 0.992
chromosome organization GO:0051276 360 0.933
gene silencing GO:0016458 138 0.932
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.858
chromatin silencing GO:0006342 76 0.816
protein maturation GO:0051604 71 0.774
negative regulation of nucleic acid templated transcription GO:1903507 240 0.634
negative regulation of gene expression GO:0010629 387 0.629
intracellular signal transduction GO:0035556 300 0.625
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.617
negative regulation of cellular metabolic process GO:0031324 382 0.551
dendrite development GO:0016358 204 0.534
germarium derived egg chamber formation GO:0007293 101 0.513
regulation of intracellular signal transduction GO:1902531 236 0.474
purine ribonucleoside metabolic process GO:0046128 127 0.456
small gtpase mediated signal transduction GO:0007264 88 0.438
negative regulation of rna metabolic process GO:0051253 251 0.426
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.423
Human Mouse
positive regulation of hydrolase activity GO:0051345 78 0.412
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.400
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.396
Human Mouse
regulation of gene expression epigenetic GO:0040029 128 0.377
negative regulation of cellular biosynthetic process GO:0031327 277 0.371
regulation of cell cycle GO:0051726 291 0.323
Mouse
regulation of protein metabolic process GO:0051246 256 0.313
regulation of molecular function GO:0065009 217 0.312
purine nucleoside catabolic process GO:0006152 112 0.308
axon development GO:0061564 297 0.302
regulation of organelle organization GO:0033043 196 0.278
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 27 0.269
aromatic compound catabolic process GO:0019439 166 0.265
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.265
axon guidance GO:0007411 233 0.259
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.246
mushroom body development GO:0016319 70 0.243
protein processing GO:0016485 68 0.221
glycosyl compound catabolic process GO:1901658 112 0.218
catabolic process GO:0009056 409 0.215
positive regulation of endopeptidase activity GO:0010950 26 0.215
axonogenesis GO:0007409 290 0.203
ribonucleoside metabolic process GO:0009119 127 0.194
regulation of cellular catabolic process GO:0031329 157 0.191
regulation of proteolysis GO:0030162 87 0.190
regulation of hydrolase activity GO:0051336 97 0.188
programmed cell death GO:0012501 257 0.183
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.172
nucleoside catabolic process GO:0009164 112 0.171
chromatin modification GO:0016568 147 0.171
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.169
regulation of cellular protein metabolic process GO:0032268 243 0.167
regulation of endopeptidase activity GO:0052548 36 0.160
negative regulation of cell communication GO:0010648 223 0.147
positive regulation of molecular function GO:0044093 136 0.138
activation of cysteine type endopeptidase activity GO:0097202 17 0.137
dendrite morphogenesis GO:0048813 199 0.135
cellular nitrogen compound catabolic process GO:0044270 165 0.127
regulation of ras protein signal transduction GO:0046578 93 0.126
organic cyclic compound catabolic process GO:1901361 168 0.122
positive regulation of peptidase activity GO:0010952 29 0.120
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.118
Human Mouse
neuron projection guidance GO:0097485 241 0.114
regulation of phosphate metabolic process GO:0019220 210 0.112
regulation of peptidase activity GO:0052547 39 0.112
nucleoside metabolic process GO:0009116 127 0.110
oocyte differentiation GO:0009994 145 0.109
central nervous system development GO:0007417 201 0.108
Mouse
negative regulation of response to stimulus GO:0048585 258 0.106
positive regulation of transcription dna templated GO:0045893 266 0.105
Human Mouse
negative regulation of transcription dna templated GO:0045892 237 0.104
heterocycle catabolic process GO:0046700 166 0.101
negative regulation of signal transduction GO:0009968 206 0.099
nucleotide metabolic process GO:0009117 161 0.099
nucleoside triphosphate metabolic process GO:0009141 120 0.098
positive regulation of catalytic activity GO:0043085 118 0.095
proteolysis GO:0006508 192 0.094
ras protein signal transduction GO:0007265 88 0.092
response to abiotic stimulus GO:0009628 341 0.092
heterochromatin organization GO:0070828 25 0.092
protein complex assembly GO:0006461 200 0.091
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.088
chemotaxis GO:0006935 249 0.088
cellular protein modification process GO:0006464 438 0.086
stem cell division GO:0017145 69 0.084
purine ribonucleoside catabolic process GO:0046130 112 0.084
nucleobase containing compound catabolic process GO:0034655 165 0.084
single organism catabolic process GO:0044712 228 0.083
apoptotic signaling pathway GO:0097190 27 0.083
positive regulation of cellular catabolic process GO:0031331 95 0.082
camera type eye morphogenesis GO:0048593 2 0.080
dna metabolic process GO:0006259 227 0.080
nucleobase containing small molecule metabolic process GO:0055086 174 0.079
chromatin organization GO:0006325 207 0.079
organonitrogen compound catabolic process GO:1901565 128 0.078
regulation of nucleotide catabolic process GO:0030811 48 0.076
negative regulation of cell differentiation GO:0045596 143 0.075
purine containing compound metabolic process GO:0072521 155 0.075
negative regulation of biosynthetic process GO:0009890 277 0.075
regulation of actin filament based process GO:0032970 42 0.074
carbohydrate derivative metabolic process GO:1901135 217 0.072
purine nucleoside metabolic process GO:0042278 127 0.071
negative regulation of signaling GO:0023057 219 0.070
appendage morphogenesis GO:0035107 397 0.068
regulation of small gtpase mediated signal transduction GO:0051056 93 0.068
regulation of catalytic activity GO:0050790 185 0.066
organonitrogen compound metabolic process GO:1901564 318 0.066
zymogen activation GO:0031638 20 0.066
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.065
axon midline choice point recognition GO:0016199 26 0.064
regulation of mitotic cell cycle phase transition GO:1901990 130 0.064
regulation of cell cycle process GO:0010564 181 0.064
Mouse
actin filament based process GO:0030029 220 0.064
positive regulation of cellular component organization GO:0051130 156 0.063
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.063
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.062
Human Mouse
organic substance catabolic process GO:1901575 308 0.062
negative regulation of protein metabolic process GO:0051248 85 0.061
dna conformation change GO:0071103 105 0.058
chromosome segregation GO:0007059 157 0.057
purine nucleoside triphosphate catabolic process GO:0009146 108 0.056
regulation of cellular amine metabolic process GO:0033238 3 0.056
chromosome condensation GO:0030261 41 0.055
retina morphogenesis in camera type eye GO:0060042 2 0.054
purine containing compound catabolic process GO:0072523 112 0.054
regulation of protein deacetylation GO:0090311 2 0.054
negative regulation of rna biosynthetic process GO:1902679 240 0.054
positive regulation of nucleotide metabolic process GO:0045981 55 0.053
regulation of cell death GO:0010941 173 0.053
gland development GO:0048732 191 0.053
protein modification process GO:0036211 438 0.051
regulation of phosphorylation GO:0042325 147 0.051
cellular amine metabolic process GO:0044106 12 0.050
sister chromatid segregation GO:0000819 92 0.050
purine nucleotide catabolic process GO:0006195 109 0.048
positive regulation of proteolysis GO:0045862 52 0.048
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.047
endocytosis GO:0006897 310 0.047
regulation of gene silencing GO:0060968 63 0.046
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.045
positive regulation of nucleoside metabolic process GO:0045979 47 0.045
positive regulation of phosphate metabolic process GO:0045937 139 0.045
regulation of cellular component biogenesis GO:0044087 201 0.045
regulation of chromatin silencing GO:0031935 36 0.045
cellular response to hydrogen peroxide GO:0070301 7 0.044
positive regulation of response to stimulus GO:0048584 323 0.044
phagocytosis GO:0006909 215 0.043
ribonucleotide metabolic process GO:0009259 145 0.042
organelle inheritance GO:0048308 2 0.042
actin cytoskeleton organization GO:0030036 206 0.041
purine ribonucleotide metabolic process GO:0009150 145 0.040
purine nucleotide metabolic process GO:0006163 146 0.039
regulation of anatomical structure morphogenesis GO:0022603 242 0.038
gonad development GO:0008406 50 0.038
Mouse Worm
small molecule metabolic process GO:0044281 305 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
Human Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.036
glycosyl compound metabolic process GO:1901657 127 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.035
mitotic cell cycle phase transition GO:0044772 138 0.034
cellular catabolic process GO:0044248 372 0.033
mitotic sister chromatid segregation GO:0000070 87 0.033
protein complex biogenesis GO:0070271 201 0.033
organelle fission GO:0048285 340 0.033
positive regulation of protein metabolic process GO:0051247 128 0.032
regulation of transcription by chromatin organization GO:0034401 3 0.032
nuclear division GO:0000280 332 0.032
hindbrain development GO:0030902 2 0.031
germarium derived female germ line cyst formation GO:0030727 42 0.031
cellular response to oxygen containing compound GO:1901701 79 0.030
regionalization GO:0003002 416 0.029
regulation of programmed cell death GO:0043067 152 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
Human Mouse
phosphorylation GO:0016310 294 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
positive regulation of cell communication GO:0010647 250 0.028
nucleotide catabolic process GO:0009166 109 0.028
localization of cell GO:0051674 257 0.028
peptidyl amino acid modification GO:0018193 105 0.028
camera type eye development GO:0043010 4 0.028
positive regulation of developmental process GO:0051094 143 0.028
organophosphate metabolic process GO:0019637 195 0.027
regulation of protein complex assembly GO:0043254 42 0.027
positive regulation of signaling GO:0023056 243 0.027
nucleoside phosphate catabolic process GO:1901292 110 0.027
cell cycle checkpoint GO:0000075 95 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
regulation of ras gtpase activity GO:0032318 38 0.026
ribonucleoside triphosphate catabolic process GO:0009203 108 0.026
regulation of cell shape GO:0008360 113 0.026
eggshell chorion assembly GO:0007306 66 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
anterior posterior pattern specification GO:0009952 136 0.026
carbohydrate derivative catabolic process GO:1901136 118 0.025
larval development GO:0002164 104 0.025
Worm
cell motility GO:0048870 251 0.025
protein phosphorylation GO:0006468 169 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
Mouse
peptidyl lysine trimethylation GO:0018023 6 0.025
gliogenesis GO:0042063 80 0.024
guanosine containing compound catabolic process GO:1901069 74 0.024
cellular response to reactive oxygen species GO:0034614 14 0.024
axon choice point recognition GO:0016198 26 0.024
regulation of catabolic process GO:0009894 170 0.024
regulation of meiosis GO:0040020 3 0.024
cell death GO:0008219 279 0.023
vesicle mediated transport GO:0016192 381 0.023
epithelial cell development GO:0002064 274 0.023
Mouse
regulation of apoptotic signaling pathway GO:2001233 10 0.022
positive regulation of signal transduction GO:0009967 223 0.022
organic substance transport GO:0071702 257 0.022
head development GO:0060322 135 0.022
Mouse
cellular response to organic substance GO:0071310 132 0.021
cell migration GO:0016477 238 0.021
regulation of mapk cascade GO:0043408 92 0.021
response to organic cyclic compound GO:0014070 89 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.020
regulation of protein modification process GO:0031399 112 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
female germ line cyst formation GO:0048135 42 0.020
dna methylation or demethylation GO:0044728 4 0.020
positive regulation of developmental growth GO:0048639 62 0.020
death GO:0016265 284 0.019
positive regulation of rac gtpase activity GO:0032855 8 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
negative regulation of intracellular signal transduction GO:1902532 57 0.019
ribonucleoside catabolic process GO:0042454 112 0.019
genitalia development GO:0048806 26 0.019
Worm
regulation of dna templated transcription in response to stress GO:0043620 4 0.019
macromolecular complex assembly GO:0065003 256 0.019
response to external biotic stimulus GO:0043207 293 0.019
regulation of cytoskeleton organization GO:0051493 89 0.018
meiotic cell cycle GO:0051321 171 0.018
response to dsrna GO:0043331 15 0.018
organophosphate catabolic process GO:0046434 112 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
Human Mouse
cell cycle dna replication GO:0044786 23 0.018
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
regulation of nucleoside metabolic process GO:0009118 50 0.017
actin filament organization GO:0007015 126 0.017
body morphogenesis GO:0010171 2 0.017
regulation of phosphatase activity GO:0010921 3 0.017
regulation of neuron differentiation GO:0045664 103 0.017
small rna loading onto risc GO:0070922 6 0.017
nucleosome mobilization GO:0042766 9 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
Human Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.016
intracellular transport GO:0046907 228 0.016
rho protein signal transduction GO:0007266 14 0.016
regulation of chromatin organization GO:1902275 32 0.016
forebrain development GO:0030900 2 0.016
Mouse
nucleocytoplasmic transport GO:0006913 72 0.016
regulation of localization GO:0032879 275 0.015
dna integrity checkpoint GO:0031570 81 0.015
cellular protein complex assembly GO:0043623 71 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.015
regulation of hemocyte proliferation GO:0035206 37 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.014
Worm
cell proliferation GO:0008283 299 0.014
regulation of gtp catabolic process GO:0033124 44 0.014
response to organic substance GO:0010033 284 0.014
Mouse
negative regulation of transcription factor import into nucleus GO:0042992 4 0.014
homeostatic process GO:0042592 199 0.014
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.014
mitotic dna damage checkpoint GO:0044773 74 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
positive regulation of cell differentiation GO:0045597 64 0.013
gene silencing by rna GO:0031047 57 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
amine metabolic process GO:0009308 12 0.013
positive regulation of organelle organization GO:0010638 65 0.013
Mouse
intracellular mrna localization GO:0008298 66 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
regulation of chromosome organization GO:0033044 64 0.013
Mouse
ovarian follicle cell development GO:0030707 248 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.012
negative regulation of organelle organization GO:0010639 56 0.012
regulation of nuclear division GO:0051783 58 0.012
neural precursor cell proliferation GO:0061351 75 0.012
positive regulation of catabolic process GO:0009896 105 0.012
rna interference GO:0016246 27 0.012
positive regulation of neurogenesis GO:0050769 41 0.012
ribonucleoside monophosphate catabolic process GO:0009158 39 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
regulation of immune system process GO:0002682 176 0.012
negative regulation of cell cycle GO:0045786 116 0.012
regulation of neurogenesis GO:0050767 158 0.011
response to ecdysone GO:0035075 34 0.011
sex differentiation GO:0007548 81 0.011
Mouse Worm
columnar cuboidal epithelial cell development GO:0002066 249 0.011
organic acid metabolic process GO:0006082 103 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
Worm
spindle organization GO:0007051 253 0.011
leg disc morphogenesis GO:0007478 80 0.011
asymmetric stem cell division GO:0098722 49 0.011
gtp catabolic process GO:0006184 72 0.011
retina development in camera type eye GO:0060041 4 0.011
response to temperature stimulus GO:0009266 106 0.010
negative regulation of protein processing GO:0010955 31 0.010
positive regulation of gene expression GO:0010628 290 0.010
Human Mouse
mitotic dna integrity checkpoint GO:0044774 75 0.010

XNP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org