Drosophila melanogaster

11 known processes

Plc21C (Dmel_CG4574)

Phospholipase C at 21C

(Aliases: PLC21c,plc21,PLC-21,plcbeta21c,Dmel\CG4574,plc-21,Plcbeta21C,PLC,PLC-21C,PLC21C,PLC[[Beta]],CG4574,plc21C)

Plc21C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 256 0.712
Mouse
small molecule metabolic process GO:0044281 305 0.709
Human
negative regulation of cellular biosynthetic process GO:0031327 277 0.705
Mouse
g protein coupled receptor signaling pathway GO:0007186 136 0.662
Mouse Rat Fly
regulation of catabolic process GO:0009894 170 0.650
Human
regulation of multicellular organismal development GO:2000026 414 0.644
Mouse Fly
growth GO:0040007 359 0.592
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.560
Human
rna catabolic process GO:0006401 37 0.533
nucleobase containing small molecule metabolic process GO:0055086 174 0.507
Human
negative regulation of biosynthetic process GO:0009890 277 0.475
Mouse
cellular catabolic process GO:0044248 372 0.427
Human Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.418
Mouse
regulation of neurogenesis GO:0050767 158 0.404
negative regulation of cellular metabolic process GO:0031324 382 0.395
Mouse
negative regulation of gene expression GO:0010629 387 0.360
Mouse
regulation of molecular function GO:0065009 217 0.359
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.344
Mouse
synaptic transmission GO:0007268 288 0.336
camp metabolic process GO:0046058 19 0.331
cell growth GO:0016049 108 0.328
regulation of cellular protein metabolic process GO:0032268 243 0.315
regulation of catalytic activity GO:0050790 185 0.311
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.310
intracellular signal transduction GO:0035556 300 0.296
Human Rat
defense response GO:0006952 300 0.283
actin filament based process GO:0030029 220 0.277
negative regulation of developmental process GO:0051093 201 0.268
Fly
cardiovascular system development GO:0072358 82 0.256
appendage development GO:0048736 401 0.254
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.250
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.249
Human
organic cyclic compound catabolic process GO:1901361 168 0.249
Human
ribose phosphate biosynthetic process GO:0046390 28 0.247
nucleotide metabolic process GO:0009117 161 0.245
Human
organophosphate metabolic process GO:0019637 195 0.239
Human Rat Fly
heterocycle catabolic process GO:0046700 166 0.236
Human
regulation of phosphate metabolic process GO:0019220 210 0.234
Human
regulation of cellular localization GO:0060341 136 0.234
Mouse
regulation of peptide hormone secretion GO:0090276 5 0.232
protein modification process GO:0036211 438 0.230
appendage morphogenesis GO:0035107 397 0.225
negative regulation of cell development GO:0010721 62 0.224
Fly
phosphorylation GO:0016310 294 0.220
Human
organic substance catabolic process GO:1901575 308 0.220
Human Rat
regulation of vesicle mediated transport GO:0060627 59 0.219
Mouse
purine containing compound biosynthetic process GO:0072522 30 0.217
macromolecule catabolic process GO:0009057 161 0.217
regulation of anatomical structure morphogenesis GO:0022603 242 0.213
Fly
synaptic vesicle localization GO:0097479 53 0.212
immune system process GO:0002376 347 0.203
Mouse Fly
regulation of cell development GO:0060284 215 0.202
Mouse Fly
negative regulation of cellular component organization GO:0051129 108 0.202
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.201
Human Mouse
positive regulation of catabolic process GO:0009896 105 0.199
Human
regulation of cellular catabolic process GO:0031329 157 0.198
Human
phototransduction GO:0007602 52 0.197
Fly
purine containing compound metabolic process GO:0072521 155 0.194
Human
mrna catabolic process GO:0006402 33 0.194
rhythmic process GO:0048511 106 0.193
Fly
negative regulation of response to stimulus GO:0048585 258 0.193
negative regulation of signaling GO:0023057 219 0.190
imaginal disc derived appendage morphogenesis GO:0035114 395 0.187
mapk cascade GO:0000165 107 0.186
Human
immune response GO:0006955 246 0.186
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.185
Human
regulation of localization GO:0032879 275 0.179
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.176
Human
nucleoside phosphate metabolic process GO:0006753 162 0.175
Human
peptidyl amino acid modification GO:0018193 105 0.174
homeostatic process GO:0042592 199 0.173
Fly
regulation of response to stress GO:0080134 200 0.172
Human
ribonucleoside metabolic process GO:0009119 127 0.172
Human
negative regulation of transcription dna templated GO:0045892 237 0.172
Mouse
catabolic process GO:0009056 409 0.169
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 316 0.167
Mouse
regulation of cell proliferation GO:0042127 163 0.167
regulation of phosphorus metabolic process GO:0051174 210 0.165
Human
positive regulation of response to stimulus GO:0048584 323 0.162
Human
negative regulation of multicellular organismal process GO:0051241 142 0.161
Fly
regulation of cell differentiation GO:0045595 302 0.161
Mouse Fly
organophosphate biosynthetic process GO:0090407 46 0.157
positive regulation of signaling GO:0023056 243 0.157
Human
purine nucleotide metabolic process GO:0006163 146 0.156
Human
negative regulation of cell communication GO:0010648 223 0.153
cation homeostasis GO:0055080 51 0.153
ribose phosphate metabolic process GO:0019693 145 0.151
Human
cellular protein modification process GO:0006464 438 0.149
imaginal disc derived appendage development GO:0048737 399 0.148
positive regulation of molecular function GO:0044093 136 0.148
Human
ribonucleotide metabolic process GO:0009259 145 0.141
Human
positive regulation of phosphate metabolic process GO:0045937 139 0.141
Human
single organism biosynthetic process GO:0044711 206 0.141
positive regulation of protein metabolic process GO:0051247 128 0.140
Mouse
establishment of localization in cell GO:0051649 402 0.138
Mouse Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.138
Human
cell proliferation GO:0008283 299 0.133
organonitrogen compound metabolic process GO:1901564 318 0.131
Human
cell migration GO:0016477 238 0.130
Mouse
purine ribonucleotide metabolic process GO:0009150 145 0.129
Human
response to other organism GO:0051707 293 0.127
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.125
Human
actin cytoskeleton organization GO:0030036 206 0.123
phototransduction visible light GO:0007603 27 0.122
Fly
vesicle mediated transport GO:0016192 381 0.121
Mouse Rat
metal ion homeostasis GO:0055065 44 0.119
gtp catabolic process GO:0006184 72 0.116
Human
rhodopsin mediated signaling pathway GO:0016056 21 0.115
Fly
regulation of programmed cell death GO:0043067 152 0.115
Fly
regulation of insulin secretion GO:0050796 5 0.115
response to transforming growth factor beta GO:0071559 18 0.114
aromatic compound catabolic process GO:0019439 166 0.114
Human
mrna metabolic process GO:0016071 124 0.112
response to endogenous stimulus GO:0009719 119 0.112
Rat
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.112
Fly
regulation of camp metabolic process GO:0030814 12 0.110
regulation of phosphorylation GO:0042325 147 0.110
Human
response to bacterium GO:0009617 198 0.109
cellular response to chemical stimulus GO:0070887 199 0.109
Human
protein transport GO:0015031 155 0.108
cyclic purine nucleotide metabolic process GO:0052652 25 0.108
signal release GO:0023061 49 0.108
regulation of behavior GO:0050795 75 0.106
purine ribonucleoside metabolic process GO:0046128 127 0.106
Human
positive regulation of cellular protein metabolic process GO:0032270 118 0.105
multi organism reproductive behavior GO:0044705 121 0.104
nucleoside phosphate biosynthetic process GO:1901293 34 0.104
response to abiotic stimulus GO:0009628 341 0.102
Fly
cell death GO:0008219 279 0.102
Fly
protein phosphorylation GO:0006468 169 0.102
glycosyl compound metabolic process GO:1901657 127 0.102
Human
innate immune response GO:0045087 144 0.101
negative regulation of cell differentiation GO:0045596 143 0.101
Fly
regulation of mitotic cell cycle GO:0007346 190 0.100
Mouse
negative regulation of insulin secretion GO:0046676 1 0.100
chemotaxis GO:0006935 249 0.099
carbohydrate derivative metabolic process GO:1901135 217 0.099
Human Mouse
deactivation of rhodopsin mediated signaling GO:0016059 17 0.098
Fly
single organism membrane organization GO:0044802 93 0.097
pathway restricted smad protein phosphorylation GO:0060389 1 0.097
compound eye morphogenesis GO:0001745 249 0.096
Fly
peptidyl threonine phosphorylation GO:0018107 2 0.095
single organism catabolic process GO:0044712 228 0.094
Human Rat
regulation of cell cycle process GO:0010564 181 0.094
Mouse
adult locomotory behavior GO:0008344 76 0.094
positive regulation of rna metabolic process GO:0051254 271 0.094
Mouse
positive regulation of signal transduction GO:0009967 223 0.094
Human
carboxylic acid metabolic process GO:0019752 92 0.094
regulation of cellular component biogenesis GO:0044087 201 0.093
cellular protein complex assembly GO:0043623 71 0.093
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.093
detection of light stimulus GO:0009583 58 0.092
Fly
regulation of mapk cascade GO:0043408 92 0.092
Human
hindbrain development GO:0030902 2 0.092
regulation of autophagy GO:0010506 62 0.091
wing disc morphogenesis GO:0007472 344 0.089
defense response to other organism GO:0098542 225 0.089
positive regulation of biosynthetic process GO:0009891 316 0.088
Mouse
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.088
purine nucleotide catabolic process GO:0006195 109 0.087
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.087
purine containing compound catabolic process GO:0072523 112 0.086
Human
cyclic nucleotide metabolic process GO:0009187 28 0.085
activation of protein kinase activity GO:0032147 12 0.083
cellular amino acid metabolic process GO:0006520 61 0.083
regulation of secretion by cell GO:1903530 39 0.083
Mouse
oxoacid metabolic process GO:0043436 103 0.083
organic substance transport GO:0071702 257 0.083
intracellular transport GO:0046907 228 0.082
Rat
post embryonic appendage morphogenesis GO:0035120 385 0.082
regulation of growth GO:0040008 233 0.081
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.081
Human Mouse
organonitrogen compound catabolic process GO:1901565 128 0.081
Human
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.078
Mouse
regulation of peptide secretion GO:0002791 6 0.077
negative regulation of rna metabolic process GO:0051253 251 0.077
Mouse
epithelial cell differentiation GO:0030855 322 0.077
cellular response to organic substance GO:0071310 132 0.077
Human
camera type eye development GO:0043010 4 0.077
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.077
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.077
Mouse
developmental growth GO:0048589 280 0.076
Mouse
cellular response to growth factor stimulus GO:0071363 30 0.076
response to oxidative stress GO:0006979 86 0.076
response to wounding GO:0009611 94 0.075
regulation of transport GO:0051049 181 0.075
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.075
Mouse
regulation of cell cycle GO:0051726 291 0.074
Mouse
cell division GO:0051301 248 0.073
Mouse
stem cell division GO:0017145 69 0.073
nucleotide biosynthetic process GO:0009165 34 0.073
ameboidal type cell migration GO:0001667 151 0.072
regulation of cell morphogenesis GO:0022604 163 0.072
extrinsic apoptotic signaling pathway GO:0097191 1 0.071
regulation of gtp catabolic process GO:0033124 44 0.071
Human
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.071
negative regulation of cell cycle phase transition GO:1901988 103 0.070
circulatory system development GO:0072359 82 0.070
body morphogenesis GO:0010171 2 0.069
negative regulation of autophagy GO:0010507 16 0.069
organophosphate catabolic process GO:0046434 112 0.069
Human Rat
positive regulation of phosphorylation GO:0042327 87 0.068
Human
secretion by cell GO:0032940 101 0.068
Mouse
cell type specific apoptotic process GO:0097285 38 0.067
nucleoside catabolic process GO:0009164 112 0.067
Human
response to organic substance GO:0010033 284 0.066
Human Rat
ion homeostasis GO:0050801 55 0.066
guanosine containing compound catabolic process GO:1901069 74 0.065
Human
secretion GO:0046903 109 0.065
Mouse
response to starvation GO:0042594 97 0.065
purine ribonucleotide catabolic process GO:0009154 109 0.064
Human
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.064
negative regulation of purine nucleotide biosynthetic process GO:1900372 3 0.063
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.063
nucleoside metabolic process GO:0009116 127 0.063
Human
purine nucleoside metabolic process GO:0042278 127 0.063
Human
regulation of protein kinase activity GO:0045859 51 0.062
regulation of apoptotic process GO:0042981 130 0.062
neurological system process GO:0050877 358 0.062
Mouse Rat Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.061
Mouse
response to oxygen containing compound GO:1901700 200 0.061
Rat
negative regulation of phosphorus metabolic process GO:0010563 45 0.061
synaptic vesicle endocytosis GO:0048488 28 0.060
purine nucleoside triphosphate catabolic process GO:0009146 108 0.060
Human
regulation of purine nucleotide metabolic process GO:1900542 62 0.060
Human
positive regulation of cellular catabolic process GO:0031331 95 0.060
Human
cellular macromolecule localization GO:0070727 220 0.060
regulation of purine nucleotide catabolic process GO:0033121 48 0.059
Human
negative regulation of nucleic acid templated transcription GO:1903507 240 0.058
Mouse
peptidyl lysine modification GO:0018205 57 0.058
regulation of nervous system development GO:0051960 248 0.058
locomotor rhythm GO:0045475 56 0.058
sensory organ morphogenesis GO:0090596 260 0.058
Fly
oocyte development GO:0048599 124 0.057
developmental maturation GO:0021700 172 0.057
negative regulation of signal transduction GO:0009968 206 0.057
positive regulation of cellular component organization GO:0051130 156 0.057
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 93 0.056
cellular macromolecule catabolic process GO:0044265 136 0.056
positive regulation of mapk cascade GO:0043410 63 0.056
Human
response to biotic stimulus GO:0009607 294 0.056
tissue migration GO:0090130 155 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.054
circadian behavior GO:0048512 76 0.054
regulation of epithelial cell proliferation GO:0050678 4 0.054
positive regulation of phosphorus metabolic process GO:0010562 139 0.054
Human
response to external biotic stimulus GO:0043207 293 0.053
regulation of protein modification process GO:0031399 112 0.053
protein acylation GO:0043543 42 0.053
regulation of neuron differentiation GO:0045664 103 0.053
detection of visible light GO:0009584 38 0.052
Fly
response to organic cyclic compound GO:0014070 89 0.052
regulation of cell size GO:0008361 63 0.052
response to growth factor GO:0070848 31 0.052
lipid modification GO:0030258 24 0.052
response to nutrient levels GO:0031667 114 0.051
reproductive behavior GO:0019098 122 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.050
organic hydroxy compound metabolic process GO:1901615 83 0.050
regulation of cellular ketone metabolic process GO:0010565 3 0.050
membrane organization GO:0061024 112 0.050
macromolecular complex assembly GO:0065003 256 0.050
tube development GO:0035295 244 0.050
positive regulation of hydrolase activity GO:0051345 78 0.050
Human
carbohydrate derivative catabolic process GO:1901136 118 0.049
Human
dna metabolic process GO:0006259 227 0.049
positive regulation of programmed cell death GO:0043068 62 0.049
phagocytosis GO:0006909 215 0.049
regulation of steroid metabolic process GO:0019218 2 0.049
regulation of neurotransmitter secretion GO:0046928 14 0.048
male mating behavior GO:0060179 70 0.048
regulation of neuron projection development GO:0010975 69 0.048
hormone biosynthetic process GO:0042446 20 0.048
positive regulation of rna biosynthetic process GO:1902680 266 0.048
Mouse
protein complex biogenesis GO:0070271 201 0.047
regulation of hormone levels GO:0010817 40 0.047
rhythmic behavior GO:0007622 76 0.047
establishment of synaptic vesicle localization GO:0097480 50 0.047
regulation of cell death GO:0010941 173 0.047
Fly
oocyte differentiation GO:0009994 145 0.046
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.046
Human
multicellular organismal reproductive behavior GO:0033057 110 0.046
cellular metal ion homeostasis GO:0006875 31 0.046
regulation of synapse structure and activity GO:0050803 128 0.046
regulation of gtpase activity GO:0043087 44 0.045
Human
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.045
translation GO:0006412 69 0.044
guanosine containing compound metabolic process GO:1901068 74 0.044
Human
oocyte axis specification GO:0007309 108 0.044
axon guidance GO:0007411 233 0.044
single organism behavior GO:0044708 391 0.044
protein localization to plasma membrane GO:0072659 13 0.044
negative regulation of peptide hormone secretion GO:0090278 1 0.044
cellular response to light stimulus GO:0071482 37 0.044
Fly
chemical homeostasis GO:0048878 92 0.044
regulation of epithelial cell differentiation GO:0030856 4 0.043
cellular ketone metabolic process GO:0042180 24 0.043
regulation of nucleotide metabolic process GO:0006140 62 0.043
Human
cellular homeostasis GO:0019725 80 0.043
regulation of organ morphogenesis GO:2000027 78 0.043
Fly
cyclic nucleotide biosynthetic process GO:0009190 25 0.043
positive regulation of nucleotide metabolic process GO:0045981 55 0.042
Human
alcohol metabolic process GO:0006066 25 0.042
hormone secretion GO:0046879 7 0.042
embryonic development via the syncytial blastoderm GO:0001700 148 0.042
cellular response to endogenous stimulus GO:0071495 80 0.042
cell cycle phase transition GO:0044770 140 0.042
Mouse
establishment of organelle localization GO:0051656 122 0.042
cell adhesion GO:0007155 136 0.042
regulation of cell cycle phase transition GO:1901987 130 0.041
Mouse
regulation of nucleoside metabolic process GO:0009118 50 0.041
Human
negative regulation of epithelial cell proliferation GO:0050680 4 0.041
response to extracellular stimulus GO:0009991 116 0.041
positive regulation of catalytic activity GO:0043085 118 0.040
Human
spermatogenesis GO:0007283 200 0.040
positive regulation of cell motility GO:2000147 3 0.040
establishment of vesicle localization GO:0051650 51 0.039
cell recognition GO:0008037 102 0.039
mating GO:0007618 120 0.039
sleep GO:0030431 49 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
regulation of protein phosphorylation GO:0001932 64 0.038
regulation of translation GO:0006417 56 0.038
male gamete generation GO:0048232 201 0.037
epithelial cell development GO:0002064 274 0.037
positive regulation of nucleoside metabolic process GO:0045979 47 0.037
Human
defense response to bacterium GO:0042742 178 0.037
organelle fission GO:0048285 340 0.037
Mouse
regulation of organelle organization GO:0033043 196 0.037
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.036
neuron projection guidance GO:0097485 241 0.036
positive regulation of intracellular signal transduction GO:1902533 116 0.036
Human
digestive system development GO:0055123 149 0.036
protein modification by small protein conjugation or removal GO:0070647 106 0.036
protein acetylation GO:0006473 39 0.035
epidermis development GO:0008544 65 0.035
protein catabolic process GO:0030163 101 0.035
divalent metal ion transport GO:0070838 26 0.035
cation transport GO:0006812 110 0.035
negative regulation of programmed cell death GO:0043069 72 0.035
Fly
mitotic nuclear division GO:0007067 213 0.034
signal transduction by phosphorylation GO:0023014 107 0.034
Human
ras protein signal transduction GO:0007265 88 0.034
chromosome organization GO:0051276 360 0.034
mesenchymal cell differentiation GO:0048762 1 0.034
positive regulation of gene expression GO:0010628 290 0.034
Mouse
positive regulation of developmental process GO:0051094 143 0.034
Mouse
heart process GO:0003015 37 0.033
ribonucleotide catabolic process GO:0009261 109 0.033
Human
response to nitrogen compound GO:1901698 90 0.033
Rat
cellular response to oxygen containing compound GO:1901701 79 0.033
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.033
peptide hormone secretion GO:0030072 5 0.033
response to decreased oxygen levels GO:0036293 58 0.033
somatic stem cell division GO:0048103 37 0.032
regulation of developmental growth GO:0048638 174 0.032
Mouse
regulation of dna metabolic process GO:0051052 34 0.032
nitrogen compound transport GO:0071705 85 0.032
response to hypoxia GO:0001666 53 0.032
learning or memory GO:0007611 141 0.032
Mouse Rat
morphogenesis of an epithelium GO:0002009 276 0.032
regulation of microtubule cytoskeleton organization GO:0070507 41 0.032
organelle localization GO:0051640 148 0.032
nucleoside triphosphate catabolic process GO:0009143 108 0.031
Human
negative regulation of catalytic activity GO:0043086 42 0.031
apoptotic process GO:0006915 159 0.031
regulation of secretion GO:0051046 44 0.031
Mouse
regulation of response to external stimulus GO:0032101 115 0.031
Fly
regulation of embryonic development GO:0045995 68 0.031
Mouse
peptide transport GO:0015833 10 0.031
multi organism behavior GO:0051705 175 0.030
protein complex assembly GO:0006461 200 0.030
cellular response to hormone stimulus GO:0032870 44 0.030
organic acid metabolic process GO:0006082 103 0.030
enteroendocrine cell differentiation GO:0035883 1 0.030
amide transport GO:0042886 10 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
tube morphogenesis GO:0035239 191 0.030
regulation of nucleotide catabolic process GO:0030811 48 0.030
Human
axonogenesis GO:0007409 290 0.030
negative regulation of organelle organization GO:0010639 56 0.030
endocytosis GO:0006897 310 0.030
regulation of cellular response to stress GO:0080135 89 0.030
Human
biological adhesion GO:0022610 138 0.029
endomembrane system organization GO:0010256 119 0.029
regulation of transcription regulatory region dna binding GO:2000677 3 0.029
tripartite regional subdivision GO:0007351 103 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.029
Mouse
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.029
localization of cell GO:0051674 257 0.029
Mouse
neurotransmitter metabolic process GO:0042133 2 0.029
steroid biosynthetic process GO:0006694 16 0.029
mushroom body development GO:0016319 70 0.029
positive regulation of organelle organization GO:0010638 65 0.029
Mouse
purine ribonucleotide biosynthetic process GO:0009152 28 0.029
regulation of neuron death GO:1901214 26 0.029
cell maturation GO:0048469 144 0.028
neuron death GO:0070997 27 0.028
cellular chemical homeostasis GO:0055082 40 0.028
determination of adult lifespan GO:0008340 137 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.028
Human
response to oxygen levels GO:0070482 59 0.028
synaptic vesicle transport GO:0048489 50 0.028
camera type eye morphogenesis GO:0048593 2 0.028
regulation of peptidase activity GO:0052547 39 0.028
positive regulation of protein phosphorylation GO:0001934 34 0.028
nuclear transcribed mrna catabolic process GO:0000956 24 0.028
negative regulation of mitotic cell cycle GO:0045930 109 0.027
covalent chromatin modification GO:0016569 106 0.027
regulation of hydrolase activity GO:0051336 97 0.027
Human
regulation of mitosis GO:0007088 56 0.027
positive regulation of nucleotide catabolic process GO:0030813 46 0.027
Human
positive regulation of epithelial cell differentiation GO:0030858 1 0.027
eye development GO:0001654 323 0.027
Fly
feeding behavior GO:0007631 50 0.027
cellular response to oxidative stress GO:0034599 28 0.027
purine ribonucleoside catabolic process GO:0046130 112 0.026
Human
positive regulation of cell death GO:0010942 69 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
response to organonitrogen compound GO:0010243 75 0.026
Rat
phenol containing compound metabolic process GO:0018958 57 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.026
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
Mouse
regulation of reproductive process GO:2000241 54 0.026
Mouse
single organism cellular localization GO:1902580 180 0.026
negative regulation of growth GO:0045926 84 0.026
regulation of protein catabolic process GO:0042176 55 0.025
head development GO:0060322 135 0.025
Mouse
cell motility GO:0048870 251 0.025
Mouse
positive regulation of apoptotic process GO:0043065 47 0.025
kidney epithelium development GO:0072073 3 0.025
chromatin organization GO:0006325 207 0.025
negative regulation of nervous system development GO:0051961 92 0.025
eye antennal disc development GO:0035214 60 0.025
regulation of immune response GO:0050776 118 0.025
eye morphogenesis GO:0048592 260 0.024
Fly
plasma membrane organization GO:0007009 26 0.024
negative regulation of neurogenesis GO:0050768 53 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
Mouse
maintenance of location GO:0051235 73 0.024
cellular ion homeostasis GO:0006873 39 0.024
synapse assembly GO:0007416 143 0.024
compound eye development GO:0048749 307 0.024
Fly
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
Human
stem cell proliferation GO:0072089 88 0.023
positive regulation of gtp catabolic process GO:0033126 43 0.023
Human
small gtpase mediated signal transduction GO:0007264 88 0.023
regulation of proteolysis GO:0030162 87 0.023
response to hexose GO:0009746 3 0.023
amine metabolic process GO:0009308 12 0.023
imaginal disc pattern formation GO:0007447 91 0.023
carbohydrate derivative biosynthetic process GO:1901137 85 0.023
Mouse
positive regulation of growth GO:0045927 75 0.023
Mouse
response to glucose GO:0009749 2 0.023
response to temperature stimulus GO:0009266 106 0.023
Fly
protein targeting to nucleus GO:0044744 51 0.023
regionalization GO:0003002 416 0.022
chitin based cuticle development GO:0040003 49 0.022
oocyte construction GO:0007308 112 0.022
glycosyl compound catabolic process GO:1901658 112 0.022
Human
response to radiation GO:0009314 155 0.022
Fly
immune response regulating signaling pathway GO:0002764 2 0.022
response to lipid GO:0033993 38 0.022
regulation of kinase activity GO:0043549 53 0.022
regulation of cell shape GO:0008360 113 0.022
negative regulation of cell cycle GO:0045786 116 0.022
microtubule polymerization or depolymerization GO:0031109 39 0.021
cellular cation homeostasis GO:0030003 38 0.021
response to trehalose GO:0010353 3 0.021
regulation of ion transport GO:0043269 39 0.021
axon development GO:0061564 297 0.021
chromosome condensation GO:0030261 41 0.021
positive regulation of cell development GO:0010720 61 0.021
cellular response to abiotic stimulus GO:0071214 58 0.021
Fly
organ growth GO:0035265 56 0.021
autophagy GO:0006914 108 0.021
cellular response to radiation GO:0071478 52 0.021
Fly
kidney development GO:0001822 3 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
Human
positive regulation of cellular component biogenesis GO:0044089 80 0.021
courtship behavior GO:0007619 68 0.021
neuron remodeling GO:0016322 29 0.021
regulation of notch signaling pathway GO:0008593 100 0.021
programmed cell death GO:0012501 257 0.021
Fly
positive regulation of protein modification process GO:0031401 58 0.021
negative regulation of catabolic process GO:0009895 36 0.021
regulation of neurotransmitter transport GO:0051588 14 0.021
histone modification GO:0016570 106 0.020
taxis GO:0042330 304 0.020
Fly
maternal determination of anterior posterior axis embryo GO:0008358 74 0.020

Plc21C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
central nervous system disease DOID:331 0 0.029
Human
disease of anatomical entity DOID:7 0 0.029
Human
neurodegenerative disease DOID:1289 0 0.029
nervous system disease DOID:863 0 0.029
Human