Drosophila melanogaster

75 known processes

Letm1 (Dmel_CG4589)

CG4589 gene product from transcript CG4589-RB

(Aliases: CG4589,dLetm1,anon60Da,Dmel\CG4589,B4D,anon-60Da)

Letm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuromuscular junction development GO:0007528 149 0.741
oocyte axis specification GO:0007309 108 0.559
oocyte construction GO:0007308 112 0.425
regionalization GO:0003002 416 0.399
mitochondrion morphogenesis GO:0070584 8 0.356
sperm mitochondrion organization GO:0030382 7 0.348
locomotory behavior GO:0007626 176 0.346
regulation of multicellular organismal development GO:2000026 414 0.329
inorganic cation transmembrane transport GO:0098662 61 0.308
establishment of localization in cell GO:0051649 402 0.304
oocyte differentiation GO:0009994 145 0.303
synaptic transmission GO:0007268 288 0.242
death GO:0016265 284 0.237
cellular macromolecule localization GO:0070727 220 0.223
oxoacid metabolic process GO:0043436 103 0.222
regulation of localization GO:0032879 275 0.221
programmed cell death GO:0012501 257 0.217
intracellular transport GO:0046907 228 0.208
organic substance transport GO:0071702 257 0.206
regulation of nurse cell apoptotic process GO:0045477 9 0.202
positive regulation of mitochondrion organization GO:0010822 8 0.199
single organism cellular localization GO:1902580 180 0.192
single organism intracellular transport GO:1902582 207 0.189
synaptic growth at neuromuscular junction GO:0051124 119 0.186
mitochondrial fission GO:0000266 8 0.186
dna metabolic process GO:0006259 227 0.174
oocyte development GO:0048599 124 0.174
blastoderm segmentation GO:0007350 159 0.171
eye development GO:0001654 323 0.167
mitochondrial fusion GO:0008053 7 0.160
embryonic axis specification GO:0000578 107 0.156
positive regulation of signal transduction GO:0009967 223 0.155
endocytosis GO:0006897 310 0.149
segmentation GO:0035282 207 0.147
organic acid metabolic process GO:0006082 103 0.141
regulation of pole plasm oskar mrna localization GO:0007317 27 0.139
immune system process GO:0002376 347 0.137
protein localization GO:0008104 284 0.136
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.135
cellular catabolic process GO:0044248 372 0.134
nucleobase containing compound catabolic process GO:0034655 165 0.134
lipid metabolic process GO:0006629 121 0.133
cell death GO:0008219 279 0.124
mitochondrion organization GO:0007005 65 0.123
ion transmembrane transport GO:0034220 122 0.121
positive regulation of cell communication GO:0010647 250 0.119
regulation of cell death GO:0010941 173 0.118
lipid biosynthetic process GO:0008610 46 0.118
organic cyclic compound catabolic process GO:1901361 168 0.117
sensory perception GO:0007600 196 0.115
regulation of transport GO:0051049 181 0.115
compound eye development GO:0048749 307 0.112
cellular macromolecule catabolic process GO:0044265 136 0.111
carboxylic acid metabolic process GO:0019752 92 0.110
catabolic process GO:0009056 409 0.110
protein complex assembly GO:0006461 200 0.109
small molecule metabolic process GO:0044281 305 0.109
regulation of mitochondrion organization GO:0010821 12 0.108
axis specification GO:0009798 167 0.108
cellular lipid metabolic process GO:0044255 83 0.103
regulation of multi organism process GO:0043900 131 0.102
establishment or maintenance of cell polarity GO:0007163 167 0.102
lipid homeostasis GO:0055088 33 0.100
transmembrane transport GO:0055085 139 0.100
positive regulation of response to stimulus GO:0048584 323 0.099
regulation of mitochondrial fusion GO:0010635 5 0.098
protein modification process GO:0036211 438 0.096
camera type eye development GO:0043010 4 0.091
tripartite regional subdivision GO:0007351 103 0.091
vesicle mediated transport GO:0016192 381 0.089
organelle localization GO:0051640 148 0.089
cytoskeleton dependent intracellular transport GO:0030705 44 0.087
regulation of protein metabolic process GO:0051246 256 0.087
homeostatic process GO:0042592 199 0.087
positive regulation of apoptotic signaling pathway GO:2001235 4 0.085
anterior posterior pattern specification GO:0009952 136 0.085
oocyte anterior posterior axis specification GO:0007314 72 0.083
negative regulation of cell communication GO:0010648 223 0.082
cellular protein modification process GO:0006464 438 0.080
apoptotic process GO:0006915 159 0.077
neutral lipid biosynthetic process GO:0046460 2 0.075
organic substance catabolic process GO:1901575 308 0.074
establishment of mitochondrion localization GO:0051654 7 0.074
positive regulation of transport GO:0051050 92 0.072
organonitrogen compound metabolic process GO:1901564 318 0.072
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.070
transcription from rna polymerase ii promoter GO:0006366 368 0.069
single organism biosynthetic process GO:0044711 206 0.069
positive regulation of cell death GO:0010942 69 0.069
single organism membrane organization GO:0044802 93 0.069
organelle fission GO:0048285 340 0.067
synapse assembly GO:0007416 143 0.067
peptide metabolic process GO:0006518 80 0.067
macromolecular complex assembly GO:0065003 256 0.067
posttranscriptional regulation of gene expression GO:0010608 145 0.065
adult locomotory behavior GO:0008344 76 0.064
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.064
imaginal disc derived appendage development GO:0048737 399 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.063
eye morphogenesis GO:0048592 260 0.062
apoptotic signaling pathway GO:0097190 27 0.062
dorsal ventral pattern formation GO:0009953 133 0.061
neuromuscular synaptic transmission GO:0007274 67 0.061
regulation of notch signaling pathway GO:0008593 100 0.061
developmental growth GO:0048589 280 0.060
synaptic vesicle endocytosis GO:0048488 28 0.060
mitochondrion localization GO:0051646 17 0.060
positive regulation of macromolecule metabolic process GO:0010604 405 0.058
negative regulation of signaling GO:0023057 219 0.058
neurological system process GO:0050877 358 0.058
heterocycle catabolic process GO:0046700 166 0.057
growth GO:0040007 359 0.057
nuclear division GO:0000280 332 0.056
establishment of organelle localization GO:0051656 122 0.056
anterior posterior axis specification GO:0009948 109 0.055
neurotransmitter transport GO:0006836 37 0.055
developmental maturation GO:0021700 172 0.054
negative regulation of signal transduction GO:0009968 206 0.054
cellular nitrogen compound catabolic process GO:0044270 165 0.053
epithelial cell development GO:0002064 274 0.053
regulation of cellular ketone metabolic process GO:0010565 3 0.053
cytokinesis GO:0000910 90 0.052
autophagy GO:0006914 108 0.052
macromolecule catabolic process GO:0009057 161 0.051
ion transport GO:0006811 145 0.051
aromatic compound catabolic process GO:0019439 166 0.051
ovarian follicle cell development GO:0030707 248 0.050
intracellular mrna localization GO:0008298 66 0.050
tube development GO:0035295 244 0.049
regulation of endocytosis GO:0030100 37 0.048
cellular macromolecular complex assembly GO:0034622 153 0.048
peptidyl amino acid modification GO:0018193 105 0.048
phagocytosis GO:0006909 215 0.047
chemical homeostasis GO:0048878 92 0.047
inorganic ion transmembrane transport GO:0098660 73 0.047
organonitrogen compound biosynthetic process GO:1901566 117 0.047
chromosome separation GO:0051304 42 0.047
intrinsic apoptotic signaling pathway GO:0097193 16 0.046
notch signaling pathway GO:0007219 120 0.046
regulation of developmental growth GO:0048638 174 0.045
sensory organ morphogenesis GO:0090596 260 0.045
modification dependent protein catabolic process GO:0019941 78 0.044
compound eye morphogenesis GO:0001745 249 0.044
regulation of reproductive process GO:2000241 54 0.043
cell proliferation GO:0008283 299 0.043
cellular protein localization GO:0034613 160 0.043
regulation of mitotic cell cycle GO:0007346 190 0.043
protein complex biogenesis GO:0070271 201 0.043
cellular amide metabolic process GO:0043603 80 0.042
body morphogenesis GO:0010171 2 0.042
cytoplasmic transport GO:0016482 130 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.041
purine nucleoside monophosphate metabolic process GO:0009126 50 0.041
ribonucleoside monophosphate metabolic process GO:0009161 51 0.041
pole plasm assembly GO:0007315 61 0.040
single organism behavior GO:0044708 391 0.040
monocarboxylic acid metabolic process GO:0032787 29 0.040
protein transport GO:0015031 155 0.040
cell motility GO:0048870 251 0.040
regulation of vesicle mediated transport GO:0060627 59 0.039
translation GO:0006412 69 0.039
atp metabolic process GO:0046034 49 0.039
cell maturation GO:0048469 144 0.039
mitotic cytokinesis GO:0000281 50 0.038
ribonucleoside monophosphate catabolic process GO:0009158 39 0.038
regulation of neural precursor cell proliferation GO:2000177 35 0.038
anatomical structure homeostasis GO:0060249 97 0.038
olfactory learning GO:0008355 56 0.038
rhythmic process GO:0048511 106 0.037
metal ion transport GO:0030001 74 0.037
membrane organization GO:0061024 112 0.037
protein localization to organelle GO:0033365 82 0.036
protein catabolic process GO:0030163 101 0.036
tube morphogenesis GO:0035239 191 0.036
extrinsic apoptotic signaling pathway GO:0097191 1 0.036
positive regulation of programmed cell death GO:0043068 62 0.036
organophosphate metabolic process GO:0019637 195 0.036
response to external biotic stimulus GO:0043207 293 0.036
apoptotic cell clearance GO:0043277 14 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.036
ribose phosphate metabolic process GO:0019693 145 0.035
epithelial cell differentiation GO:0030855 322 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
mitotic spindle organization GO:0007052 220 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.033
larval behavior GO:0030537 42 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
interspecies interaction between organisms GO:0044419 16 0.033
phosphorylation GO:0016310 294 0.033
purine ribonucleotide catabolic process GO:0009154 109 0.033
mitotic nuclear division GO:0007067 213 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
spermatid development GO:0007286 98 0.032
response to biotic stimulus GO:0009607 294 0.032
purine containing compound metabolic process GO:0072521 155 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
cellular response to sterol depletion GO:0071501 3 0.032
developmental programmed cell death GO:0010623 138 0.031
nucleus organization GO:0006997 45 0.031
response to virus GO:0009615 28 0.031
wing disc morphogenesis GO:0007472 344 0.031
positive regulation of apoptotic process GO:0043065 47 0.031
cellular amine metabolic process GO:0044106 12 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.031
macroautophagy GO:0016236 42 0.031
negative regulation of protein depolymerization GO:1901880 23 0.031
organelle fusion GO:0048284 46 0.030
cellular ketone metabolic process GO:0042180 24 0.030
biological adhesion GO:0022610 138 0.030
regulation of cellular localization GO:0060341 136 0.030
maternal determination of anterior posterior axis embryo GO:0008358 74 0.030
triglyceride biosynthetic process GO:0019432 2 0.030
regulation of secretion GO:0051046 44 0.030
ubiquitin dependent protein catabolic process GO:0006511 78 0.029
purine ribonucleoside metabolic process GO:0046128 127 0.029
nucleoside catabolic process GO:0009164 112 0.029
protein ubiquitination GO:0016567 70 0.029
localization of cell GO:0051674 257 0.029
determination of adult lifespan GO:0008340 137 0.029
sensory perception of chemical stimulus GO:0007606 116 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.028
salivary gland cell autophagic cell death GO:0035071 83 0.028
dorsal ventral axis specification GO:0009950 66 0.028
forebrain development GO:0030900 2 0.028
chaeta development GO:0022416 97 0.028
regulation of secretion by cell GO:1903530 39 0.027
regulation of synaptic transmission GO:0050804 69 0.027
water homeostasis GO:0030104 3 0.027
eye photoreceptor cell differentiation GO:0001754 145 0.027
synapse organization GO:0050808 196 0.027
nucleoside monophosphate metabolic process GO:0009123 52 0.027
sulfur compound metabolic process GO:0006790 59 0.027
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.027
regulation of programmed cell death GO:0043067 152 0.026
atp catabolic process GO:0006200 38 0.026
cellular response to chemical stimulus GO:0070887 199 0.026
cardiovascular system development GO:0072358 82 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.026
microtubule organizing center organization GO:0031023 168 0.026
cellular homeostasis GO:0019725 80 0.026
imaginal disc derived wing vein specification GO:0007474 48 0.025
embryonic morphogenesis GO:0048598 206 0.025
digestive system development GO:0055123 149 0.025
cortical cytoskeleton organization GO:0030865 29 0.025
negative regulation of cell death GO:0060548 81 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
regulation of growth GO:0040008 233 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.025
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
positive regulation of cellular catabolic process GO:0031331 95 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
actin mediated cell contraction GO:0070252 21 0.024
detection of stimulus GO:0051606 156 0.024
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
metal ion homeostasis GO:0055065 44 0.024
taxis GO:0042330 304 0.024
proteolysis GO:0006508 192 0.024
cell cycle phase transition GO:0044770 140 0.024
nucleotide metabolic process GO:0009117 161 0.024
glutamate secretion GO:0014047 1 0.024
spindle organization GO:0007051 253 0.023
mitochondrion distribution GO:0048311 10 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
positive regulation of organelle organization GO:0010638 65 0.023
acylglycerol metabolic process GO:0006639 12 0.023
positive regulation of intracellular signal transduction GO:1902533 116 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
aging GO:0007568 143 0.022
larval development GO:0002164 104 0.022
establishment of spindle localization GO:0051293 22 0.022
regulation of anatomical structure size GO:0090066 163 0.022
centrosome organization GO:0051297 163 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.022
regulation of organelle organization GO:0033043 196 0.022
actin filament based process GO:0030029 220 0.021
microtubule based transport GO:0010970 42 0.021
pole plasm mrna localization GO:0019094 49 0.021
synaptic vesicle recycling GO:0036465 28 0.021
spermatogenesis GO:0007283 200 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
negative regulation of bmp signaling pathway GO:0030514 12 0.021
response to other organism GO:0051707 293 0.021
endosomal transport GO:0016197 44 0.021
regulation of apoptotic process GO:0042981 130 0.021
amine metabolic process GO:0009308 12 0.021
mesenchymal cell development GO:0014031 1 0.021
cell migration GO:0016477 238 0.021
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.020
synaptic transmission dopaminergic GO:0001963 2 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
response to organic substance GO:0010033 284 0.020
mrna metabolic process GO:0016071 124 0.020
striated muscle myosin thick filament assembly GO:0071688 3 0.020
appendage morphogenesis GO:0035107 397 0.020
regulation of cell cycle GO:0051726 291 0.020
secretion GO:0046903 109 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
gland morphogenesis GO:0022612 145 0.019
nuclear transcribed mrna catabolic process GO:0000956 24 0.019
positive regulation of developmental process GO:0051094 143 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
response to fungus GO:0009620 50 0.019
regulation of cellular response to stress GO:0080135 89 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
peripheral nervous system development GO:0007422 52 0.019
positive regulation of signaling GO:0023056 243 0.019
multicellular organism growth GO:0035264 46 0.019
mitotic sister chromatid segregation GO:0000070 87 0.019
appendage development GO:0048736 401 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
retina development in camera type eye GO:0060041 4 0.019
tissue morphogenesis GO:0048729 297 0.019
regulation of synapse structure and activity GO:0050803 128 0.018
negative regulation of cellular response to oxidative stress GO:1900408 1 0.018
protein phosphorylation GO:0006468 169 0.018
regulation of synapse organization GO:0050807 110 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
intracellular signal transduction GO:0035556 300 0.018
response to endoplasmic reticulum stress GO:0034976 28 0.018
positive regulation of phagocytosis engulfment GO:0060100 1 0.018
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.018
spermatid differentiation GO:0048515 114 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
establishment of protein localization GO:0045184 163 0.018
meiotic cytokinesis GO:0033206 33 0.018
cell division GO:0051301 248 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
negative regulation of cytoskeleton organization GO:0051494 30 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.018
mitotic sister chromatid separation GO:0051306 30 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
detection of chemical stimulus GO:0009593 93 0.017
negative regulation of erbb signaling pathway GO:1901185 29 0.017
negative regulation of organelle organization GO:0010639 56 0.017
kidney development GO:0001822 3 0.017
response to copper ion GO:0046688 4 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.017
negative regulation of growth GO:0045926 84 0.017
regulation of cell differentiation GO:0045595 302 0.017
negative regulation of gene expression GO:0010629 387 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
molting cycle chitin based cuticle GO:0007591 56 0.017
molting cycle GO:0042303 56 0.017
regulation of mitochondrial fission GO:0090140 7 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
response to abiotic stimulus GO:0009628 341 0.017
rna localization GO:0006403 115 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
response to nutrient levels GO:0031667 114 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
nucleoside metabolic process GO:0009116 127 0.016
response to temperature stimulus GO:0009266 106 0.016
regulation of response to oxidative stress GO:1902882 4 0.016
purine containing compound catabolic process GO:0072523 112 0.016
detection of stimulus involved in sensory perception GO:0050906 92 0.016
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
acylglycerol biosynthetic process GO:0046463 2 0.016
cytoplasm organization GO:0007028 64 0.016
macromolecular complex disassembly GO:0032984 37 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
respiratory system development GO:0060541 213 0.016
wound healing GO:0042060 75 0.016
centrosome duplication GO:0051298 121 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
eye pigment metabolic process GO:0042441 33 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.015
regulation of phosphorylation GO:0042325 147 0.015
membrane fusion GO:0061025 42 0.015
negative regulation of actin filament depolymerization GO:0030835 2 0.015
protein complex disassembly GO:0043241 36 0.015
epidermal growth factor receptor signaling pathway GO:0007173 58 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
dendrite morphogenesis GO:0048813 199 0.015
regulation of mitotic sister chromatid segregation GO:0033047 28 0.015
regulation of erbb signaling pathway GO:1901184 42 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
centrosome cycle GO:0007098 137 0.015
regulation of system process GO:0044057 36 0.015
cation transmembrane transport GO:0098655 88 0.015
negative regulation of response to oxidative stress GO:1902883 1 0.015
transition metal ion transport GO:0000041 16 0.015
cellular protein catabolic process GO:0044257 83 0.015
oocyte dorsal ventral axis specification GO:0007310 34 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
cellular protein complex assembly GO:0043623 71 0.015
regulation of microtubule based process GO:0032886 49 0.015
digestive tract development GO:0048565 149 0.015
small rna loading onto risc GO:0070922 6 0.015
secretion by cell GO:0032940 101 0.014
positive regulation of calcium ion transport GO:0051928 4 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of catabolic process GO:0009894 170 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
response to extracellular stimulus GO:0009991 116 0.014
regulation of membrane potential GO:0042391 35 0.014
detection of external stimulus GO:0009581 66 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
positive regulation of cytoskeleton organization GO:0051495 21 0.014
glial cell development GO:0021782 27 0.014
positive regulation of catabolic process GO:0009896 105 0.014
maintenance of protein location in cell GO:0032507 26 0.014
neuroblast proliferation GO:0007405 74 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
establishment of cell polarity GO:0030010 40 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
response to light stimulus GO:0009416 124 0.014
acid secretion GO:0046717 1 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
cellular response to mechanical stimulus GO:0071260 2 0.014
regulation of mitotic sister chromatid separation GO:0010965 28 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.014
neural precursor cell proliferation GO:0061351 75 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
cation transport GO:0006812 110 0.014
multicellular organismal aging GO:0010259 140 0.013
regulation of response to stress GO:0080134 200 0.013
exocytosis GO:0006887 28 0.013
regulation of autophagy GO:0010506 62 0.013
chromosome segregation GO:0007059 157 0.013
adult behavior GO:0030534 137 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
establishment of mitochondrion localization microtubule mediated GO:0034643 6 0.013
instar larval development GO:0002168 55 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
steroid biosynthetic process GO:0006694 16 0.012
cation homeostasis GO:0055080 51 0.012
chromosome organization GO:0051276 360 0.012
cellular component disassembly GO:0022411 46 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
spindle localization GO:0051653 22 0.012
larval locomotory behavior GO:0008345 27 0.012
calcium ion transport GO:0006816 24 0.012
regulation of nuclear division GO:0051783 58 0.012
lysosomal transport GO:0007041 13 0.012
metaphase anaphase transition of cell cycle GO:0044784 28 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
positive regulation of protein phosphorylation GO:0001934 34 0.012
pole cell formation GO:0007279 19 0.012
protein targeting GO:0006605 64 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
axon development GO:0061564 297 0.012
imaginal disc pattern formation GO:0007447 91 0.012
positive regulation of multicellular organism growth GO:0040018 21 0.012
response to organonitrogen compound GO:0010243 75 0.012
single organism catabolic process GO:0044712 228 0.011
regulation of cell cycle process GO:0010564 181 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
cell aging GO:0007569 2 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of protein localization GO:0032880 76 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
positive regulation of phagocytosis GO:0050766 3 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
positive regulation of lipid biosynthetic process GO:0046889 3 0.011
response to nitrogen compound GO:1901698 90 0.011
nucleotide catabolic process GO:0009166 109 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
mapk cascade GO:0000165 107 0.011
humoral immune response GO:0006959 117 0.011
erbb signaling pathway GO:0038127 58 0.011
glial cell differentiation GO:0010001 35 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
germarium derived oocyte differentiation GO:0030706 29 0.011
regulation of cell maturation GO:1903429 27 0.011
detection of abiotic stimulus GO:0009582 66 0.011
purine nucleoside monophosphate catabolic process GO:0009128 38 0.011

Letm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.172
cardiovascular system disease DOID:1287 0 0.024
central nervous system disease DOID:331 0 0.023
neurodegenerative disease DOID:1289 0 0.023
nervous system disease DOID:863 0 0.023
muscular disease DOID:0080000 0 0.017
musculoskeletal system disease DOID:17 0 0.017
renal tubular transport disease DOID:447 0 0.016
kidney disease DOID:557 0 0.016
urinary system disease DOID:18 0 0.016
parkinson s disease DOID:14330 0 0.014
synucleinopathy DOID:0050890 0 0.014
motor neuron disease DOID:231 0 0.011