Drosophila melanogaster

62 known processes

inx2 (Dmel_CG4590)

innexin 2

(Aliases: l(1)G0035,Dmel\CG4590,Inx2,prp33,l(1)G0059,l(1)G0364,CG4590,Dm-inx,l(1)G0157,l(1)G0118,l(1)G0317,Dm-inx2,l(1)G0036,kropf,l(1)G0043,Ix2,inx-2,D-inx-2,INX-2)

inx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract development GO:0048565 149 0.914
digestive system development GO:0055123 149 0.802
g protein coupled receptor signaling pathway GO:0007186 136 0.779
positive regulation of transcription dna templated GO:0045893 266 0.671
morphogenesis of embryonic epithelium GO:0016331 94 0.646
tube development GO:0035295 244 0.626
epithelial cell migration GO:0010631 148 0.604
olfactory behavior GO:0042048 97 0.555
multi multicellular organism process GO:0044706 123 0.514
positive regulation of rna metabolic process GO:0051254 271 0.488
imaginal disc derived appendage morphogenesis GO:0035114 395 0.485
regulation of nervous system development GO:0051960 248 0.482
embryonic morphogenesis GO:0048598 206 0.436
branching involved in open tracheal system development GO:0060446 45 0.419
sensory perception of smell GO:0007608 80 0.409
cell projection assembly GO:0030031 94 0.393
digestive tract morphogenesis GO:0048546 127 0.372
positive regulation of gene expression GO:0010628 290 0.361
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.360
tube morphogenesis GO:0035239 191 0.341
embryonic development via the syncytial blastoderm GO:0001700 148 0.337
stem cell differentiation GO:0048863 117 0.330
positive regulation of signaling GO:0023056 243 0.327
mating GO:0007618 120 0.316
regulation of cell morphogenesis GO:0022604 163 0.306
positive regulation of rna biosynthetic process GO:1902680 266 0.294
multi organism behavior GO:0051705 175 0.293
associative learning GO:0008306 65 0.284
cognition GO:0050890 141 0.281
cell cell junction organization GO:0045216 55 0.280
Fly
axon development GO:0061564 297 0.274
regulation of cell differentiation GO:0045595 302 0.258
Worm
actin filament bundle organization GO:0061572 28 0.258
protein complex biogenesis GO:0070271 201 0.251
tissue migration GO:0090130 155 0.248
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.247
regulation of response to stress GO:0080134 200 0.245
memory GO:0007613 94 0.236
actin cytoskeleton organization GO:0030036 206 0.226
female germ line stem cell asymmetric division GO:0048132 14 0.210
dopamine biosynthetic process GO:0042416 3 0.203
detection of stimulus GO:0051606 156 0.202
Fly
chitin based cuticle sclerotization GO:0007593 19 0.185
wing disc morphogenesis GO:0007472 344 0.184
long term memory GO:0007616 62 0.181
germ line stem cell maintenance GO:0030718 50 0.179
chromosome organization GO:0051276 360 0.178
intercellular transport GO:0010496 2 0.176
multi organism reproductive behavior GO:0044705 121 0.176
tissue morphogenesis GO:0048729 297 0.165
cellular component assembly involved in morphogenesis GO:0010927 151 0.164
response to external biotic stimulus GO:0043207 293 0.163
regulation of multicellular organismal development GO:2000026 414 0.162
cuticle development GO:0042335 86 0.161
cell migration GO:0016477 238 0.157
head involution GO:0008258 35 0.156
locomotory behavior GO:0007626 176 0.154
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.142
positive regulation of nucleic acid templated transcription GO:1903508 266 0.138
homeostatic process GO:0042592 199 0.137
Fly
chemosensory behavior GO:0007635 106 0.136
post embryonic appendage morphogenesis GO:0035120 385 0.135
regulation of intracellular signal transduction GO:1902531 236 0.123
localization of cell GO:0051674 257 0.123
embryo development ending in birth or egg hatching GO:0009792 152 0.120
Worm
germarium derived female germ line cyst formation GO:0030727 42 0.120
chromatin organization GO:0006325 207 0.119
positive regulation of response to stimulus GO:0048584 323 0.117
epithelial cell differentiation GO:0030855 322 0.117
regulation of response to external stimulus GO:0032101 115 0.114
cellular protein modification process GO:0006464 438 0.113
epithelial cell cell adhesion GO:0090136 6 0.110
regulation of cellular component biogenesis GO:0044087 201 0.106
gliogenesis GO:0042063 80 0.105
ovarian follicle cell development GO:0030707 248 0.104
peptidyl amino acid modification GO:0018193 105 0.104
single organism behavior GO:0044708 391 0.104
organelle localization GO:0051640 148 0.102
molting cycle process GO:0022404 29 0.101
reproductive behavior GO:0019098 122 0.098
glial cell migration GO:0008347 31 0.096
regulation of immune response GO:0050776 118 0.095
foregut morphogenesis GO:0007440 10 0.092
negative regulation of cell differentiation GO:0045596 143 0.092
Worm
actin filament based process GO:0030029 220 0.091
cell motility GO:0048870 251 0.090
positive regulation of cell communication GO:0010647 250 0.089
cortical actin cytoskeleton organization GO:0030866 24 0.088
cell adhesion GO:0007155 136 0.087
actin filament bundle assembly GO:0051017 26 0.086
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.084
regulation of cell shape GO:0008360 113 0.083
molting cycle chitin based cuticle GO:0007591 56 0.081
reproductive system development GO:0061458 74 0.080
positive regulation of biosynthetic process GO:0009891 316 0.079
regulation of phosphorylation GO:0042325 147 0.079
macromolecular complex assembly GO:0065003 256 0.079
regulation of protein metabolic process GO:0051246 256 0.078
cuticle pigmentation GO:0048067 22 0.074
columnar cuboidal epithelial cell development GO:0002066 249 0.073
reproductive structure development GO:0048608 74 0.072
stem cell maintenance GO:0019827 67 0.072
positive regulation of cellular component biogenesis GO:0044089 80 0.071
organonitrogen compound metabolic process GO:1901564 318 0.070
ameboidal type cell migration GO:0001667 151 0.067
malpighian tubule morphogenesis GO:0007443 44 0.067
negative regulation of transcription dna templated GO:0045892 237 0.066
negative regulation of nervous system development GO:0051961 92 0.065
actin filament organization GO:0007015 126 0.065
regulation of membrane potential GO:0042391 35 0.064
Fly
regulation of cytoskeleton organization GO:0051493 89 0.064
protein modification process GO:0036211 438 0.063
detection of stimulus involved in sensory perception GO:0050906 92 0.061
regulation of anatomical structure morphogenesis GO:0022603 242 0.060
dorsal closure GO:0007391 79 0.060
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.060
initiation of dorsal closure GO:0007392 12 0.058
sensory perception of chemical stimulus GO:0007606 116 0.058
aromatic amino acid family metabolic process GO:0009072 3 0.056
neurological system process GO:0050877 358 0.055
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.055
ovarian follicle cell migration GO:0007297 121 0.054
open tracheal system development GO:0007424 204 0.054
forebrain development GO:0030900 2 0.053
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
germline stem cell asymmetric division GO:0098728 15 0.052
positive regulation of cell migration GO:0030335 2 0.052
central nervous system development GO:0007417 201 0.052
sensory perception GO:0007600 196 0.052
female germ line stem cell maintenance GO:0036099 8 0.051
male mating behavior GO:0060179 70 0.051
circulatory system development GO:0072359 82 0.051
cellular catabolic process GO:0044248 372 0.051
protein complex assembly GO:0006461 200 0.051
regulation of phosphorus metabolic process GO:0051174 210 0.050
hindgut morphogenesis GO:0007442 58 0.049
regulation of embryonic cell shape GO:0016476 30 0.049
axonogenesis GO:0007409 290 0.048
establishment of tissue polarity GO:0007164 87 0.048
periodic partitioning GO:0007365 29 0.048
sensory organ morphogenesis GO:0090596 260 0.048
organic substance catabolic process GO:1901575 308 0.048
striated muscle cell differentiation GO:0051146 90 0.048
photoreceptor cell differentiation GO:0046530 170 0.048
asymmetric cell division GO:0008356 37 0.048
intracellular signal transduction GO:0035556 300 0.048
mating behavior GO:0007617 106 0.047
female germ line cyst formation GO:0048135 42 0.047
gonad development GO:0008406 50 0.047
chromatin assembly GO:0031497 48 0.045
germarium derived female germ line cyst encapsulation GO:0030708 8 0.045
establishment of organelle localization GO:0051656 122 0.045
compound eye development GO:0048749 307 0.044
regulation of cellular protein metabolic process GO:0032268 243 0.044
cell growth GO:0016049 108 0.044
dorsal closure spreading of leading edge cells GO:0007395 4 0.043
apical junction assembly GO:0043297 32 0.043
cellular macromolecular complex assembly GO:0034622 153 0.043
phosphorylation GO:0016310 294 0.043
hindgut development GO:0061525 58 0.042
dopamine metabolic process GO:0042417 7 0.042
neuroblast division GO:0055057 35 0.042
positive regulation of signal transduction GO:0009967 223 0.041
appendage morphogenesis GO:0035107 397 0.041
morphogenesis of an epithelium GO:0002009 276 0.041
chorion containing eggshell formation GO:0007304 105 0.041
germ band extension GO:0007377 11 0.040
taxis GO:0042330 304 0.040
organelle fission GO:0048285 340 0.039
convergent extension involved in gastrulation GO:0060027 2 0.038
muscle attachment GO:0016203 36 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
morphogenesis of a polarized epithelium GO:0001738 93 0.038
multicellular organismal reproductive behavior GO:0033057 110 0.037
positive regulation of cell cycle GO:0045787 43 0.037
glial cell differentiation GO:0010001 35 0.037
segmentation GO:0035282 207 0.036
cellular protein complex assembly GO:0043623 71 0.036
epithelium migration GO:0090132 148 0.036
response to other organism GO:0051707 293 0.036
positive regulation of protein metabolic process GO:0051247 128 0.035
positive regulation of phosphate metabolic process GO:0045937 139 0.035
cell junction organization GO:0034330 57 0.035
Fly
regulation of cell development GO:0060284 215 0.035
Worm
tricarboxylic acid metabolic process GO:0072350 1 0.035
gastrulation involving germ band extension GO:0010004 36 0.034
actin filament based movement GO:0030048 26 0.034
epithelial tube morphogenesis GO:0060562 88 0.033
chromosome segregation GO:0007059 157 0.033
sex differentiation GO:0007548 81 0.033
regulation of wound healing GO:0061041 13 0.033
oocyte axis specification GO:0007309 108 0.032
imaginal disc derived appendage development GO:0048737 399 0.032
ubiquitin dependent protein catabolic process GO:0006511 78 0.032
neuroblast fate commitment GO:0014017 19 0.032
alpha amino acid metabolic process GO:1901605 20 0.031
response to abiotic stimulus GO:0009628 341 0.031
Fly
regulation of cell projection organization GO:0031344 92 0.031
regulation of catalytic activity GO:0050790 185 0.031
appendage development GO:0048736 401 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
serotonin metabolic process GO:0042428 2 0.030
oviposition GO:0018991 19 0.030
imaginal disc derived female genitalia development GO:0007486 6 0.030
macromolecule catabolic process GO:0009057 161 0.030
synapse assembly GO:0007416 143 0.029
cellular amide metabolic process GO:0043603 80 0.029
response to carbon dioxide GO:0010037 4 0.029
primary amino compound biosynthetic process GO:1901162 2 0.029
protein catabolic process GO:0030163 101 0.029
rhythmic process GO:0048511 106 0.029
striated muscle cell development GO:0055002 50 0.029
regulation of innate immune response GO:0045088 71 0.029
chemotaxis GO:0006935 249 0.029
cellular amine metabolic process GO:0044106 12 0.028
oocyte development GO:0048599 124 0.028
Worm
ventral cord development GO:0007419 16 0.028
cell cell junction assembly GO:0007043 38 0.028
Fly
cell migration involved in gastrulation GO:0042074 9 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.027
gastrulation with mouth forming first GO:0001703 36 0.027
germarium derived egg chamber formation GO:0007293 101 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
stem cell division GO:0017145 69 0.026
embryonic hindgut morphogenesis GO:0048619 48 0.026
genital disc development GO:0035215 44 0.026
developmental maturation GO:0021700 172 0.026
Worm
determination of adult lifespan GO:0008340 137 0.026
Worm
regulation of chitin based cuticle tanning GO:0007564 14 0.026
regulation of epithelial cell proliferation GO:0050678 4 0.025
stem cell development GO:0048864 79 0.025
epithelial cell migration open tracheal system GO:0007427 32 0.025
segment polarity determination GO:0007367 25 0.025
gastrulation GO:0007369 70 0.025
carboxylic acid metabolic process GO:0019752 92 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.024
axon extension GO:0048675 32 0.024
eggshell chorion assembly GO:0007306 66 0.024
detection of light stimulus GO:0009583 58 0.024
Fly
catabolic process GO:0009056 409 0.024
regulation of organelle organization GO:0033043 196 0.024
positive regulation of defense response GO:0031349 59 0.024
regulation of developmental pigmentation GO:0048070 24 0.023
amine metabolic process GO:0009308 12 0.023
regulation of gene expression epigenetic GO:0040029 128 0.023
eye morphogenesis GO:0048592 260 0.023
regulation of behavior GO:0050795 75 0.022
development of primary sexual characteristics GO:0045137 50 0.022
learning or memory GO:0007611 141 0.022
cell proliferation GO:0008283 299 0.022
growth GO:0040007 359 0.022
positive regulation of gtp catabolic process GO:0033126 43 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
rna processing GO:0006396 147 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
spermatogenesis GO:0007283 200 0.021
dorsal closure elongation of leading edge cells GO:0007394 10 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
aging GO:0007568 143 0.021
Worm
regulation of malpighian tubule diameter GO:0035297 3 0.020
mitotic sister chromatid separation GO:0051306 30 0.020
oocyte construction GO:0007308 112 0.020
defense response to gram negative bacterium GO:0050829 94 0.020
establishment of vesicle localization GO:0051650 51 0.020
heterocycle catabolic process GO:0046700 166 0.020
response to wounding GO:0009611 94 0.020
blastoderm segmentation GO:0007350 159 0.020
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.020
apical constriction involved in gastrulation GO:0003384 7 0.020
motor neuron axon guidance GO:0008045 58 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
adherens junction organization GO:0034332 27 0.019
branch fusion open tracheal system GO:0035147 17 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
mrna metabolic process GO:0016071 124 0.019
nuclear division GO:0000280 332 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
dorsal appendage formation GO:0046843 47 0.018
positive regulation of kinase activity GO:0033674 25 0.018
nucleotide catabolic process GO:0009166 109 0.018
axon choice point recognition GO:0016198 26 0.018
asymmetric stem cell division GO:0098722 49 0.018
apical constriction GO:0003383 18 0.018
protein phosphorylation GO:0006468 169 0.017
germ line cyst formation GO:0048134 44 0.017
circadian behavior GO:0048512 76 0.017
chromatin modification GO:0016568 147 0.017
embryonic pattern specification GO:0009880 174 0.016
establishment of spindle orientation GO:0051294 18 0.016
actomyosin structure organization GO:0031032 56 0.016
meiotic cell cycle GO:0051321 171 0.016
regulation of locomotion GO:0040012 42 0.016
cell junction assembly GO:0034329 42 0.016
Fly
chromatin assembly or disassembly GO:0006333 52 0.016
regulation of neuron differentiation GO:0045664 103 0.016
regulation of membrane depolarization GO:0003254 1 0.016
Fly
regulation of defense response GO:0031347 102 0.016
regulation of molecular function GO:0065009 217 0.016
negative regulation of epithelial cell proliferation GO:0050680 4 0.016
branching morphogenesis of an epithelial tube GO:0048754 45 0.015
positive regulation of response to wounding GO:1903036 15 0.015
programmed cell death GO:0012501 257 0.015
Worm
response to ethanol GO:0045471 59 0.015
oxoacid metabolic process GO:0043436 103 0.015
positive regulation of molecular function GO:0044093 136 0.015
cell fate determination GO:0001709 91 0.015
death GO:0016265 284 0.015
Worm
neuron recognition GO:0008038 101 0.015
regulation of anatomical structure size GO:0090066 163 0.015
cell maturation GO:0048469 144 0.015
Worm
regulation of cell cycle GO:0051726 291 0.015
molting cycle GO:0042303 56 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
citrate metabolic process GO:0006101 0 0.014
mitotic nuclear division GO:0007067 213 0.014
female germ line cyst encapsulation GO:0048139 8 0.014
aromatic compound catabolic process GO:0019439 166 0.014
fusome organization GO:0045478 13 0.014
cardiocyte differentiation GO:0035051 29 0.014
r7 cell fate commitment GO:0007465 12 0.014
small molecule metabolic process GO:0044281 305 0.014
filopodium assembly GO:0046847 33 0.014
epithelial cell development GO:0002064 274 0.013
vesicle localization GO:0051648 55 0.013
histone modification GO:0016570 106 0.013
regulation of tube diameter GO:0035296 14 0.013
regulation of immune system process GO:0002682 176 0.013
genitalia development GO:0048806 26 0.013
determination of digestive tract left right asymmetry GO:0071907 6 0.013
wound healing GO:0042060 75 0.013
indole containing compound biosynthetic process GO:0042435 4 0.013
oocyte differentiation GO:0009994 145 0.013
Worm
germ line cyst encapsulation GO:0048138 8 0.013
nucleus organization GO:0006997 45 0.013
neurotransmitter transport GO:0006836 37 0.013
morphogenesis of follicular epithelium GO:0016333 36 0.012
cardiovascular system development GO:0072358 82 0.012
skeletal muscle organ development GO:0060538 48 0.012
negative regulation of protein processing GO:0010955 31 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
body morphogenesis GO:0010171 2 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
border follicle cell migration GO:0007298 113 0.012
regulation of cell growth GO:0001558 43 0.012
compound eye retinal cell programmed cell death GO:0046667 23 0.012
eye development GO:0001654 323 0.012
cell substrate adhesion GO:0031589 10 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of tube size open tracheal system GO:0035151 43 0.012
regulation of actin filament based process GO:0032970 42 0.012
eye photoreceptor cell fate commitment GO:0042706 37 0.012
rho protein signal transduction GO:0007266 14 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
regulation of actin cytoskeleton organization GO:0032956 42 0.011
germarium derived oocyte fate determination GO:0007294 26 0.011
establishment of planar polarity GO:0001736 87 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.011
morphogenesis of a branching epithelium GO:0061138 45 0.011
neuroblast development GO:0014019 13 0.011
feeding behavior GO:0007631 50 0.011
apoptotic process GO:0006915 159 0.011
Worm
negative regulation of cell development GO:0010721 62 0.011
Worm
response to nutrient levels GO:0031667 114 0.011
meiotic cell cycle phase transition GO:0044771 4 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
neuron projection guidance GO:0097485 241 0.011
catechol containing compound metabolic process GO:0009712 10 0.011
rna splicing GO:0008380 83 0.011
biological adhesion GO:0022610 138 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
regulation of reproductive process GO:2000241 54 0.011
Worm
response to organic cyclic compound GO:0014070 89 0.011
regulation of hydrolase activity GO:0051336 97 0.011
genitalia morphogenesis GO:0035112 16 0.011
negative regulation of gene expression GO:0010629 387 0.011
dna endoreduplication GO:0042023 22 0.011
response to light stimulus GO:0009416 124 0.011
Fly
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
multicellular organismal aging GO:0010259 140 0.011
Worm
asymmetric neuroblast division GO:0055059 33 0.011
signal transduction by phosphorylation GO:0023014 107 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
circadian rhythm GO:0007623 105 0.010
regulation of mapk cascade GO:0043408 92 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
spiracle morphogenesis open tracheal system GO:0035277 22 0.010
detection of external stimulus GO:0009581 66 0.010
Fly
axis elongation GO:0003401 3 0.010
intracellular receptor signaling pathway GO:0030522 19 0.010
imaginal disc derived wing vein specification GO:0007474 48 0.010

inx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org