Drosophila melanogaster

0 known processes

Tpr2 (Dmel_CG4599)

Tetratricopeptide repeat protein 2

(Aliases: EU3220,CG4599,Dmel\CG4599,BEST:LD24941,dtpr2,dtrpr2,tpr2,dTpr2,Trp2,dTPR2)

Tpr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.111
protein modification by small protein conjugation or removal GO:0070647 106 0.107
programmed cell death GO:0012501 257 0.100
nuclear division GO:0000280 332 0.097
regulation of cell cycle GO:0051726 291 0.094
protein transport GO:0015031 155 0.077
phosphorylation GO:0016310 294 0.076
death GO:0016265 284 0.076
cellular macromolecule localization GO:0070727 220 0.073
protein modification by small protein removal GO:0070646 28 0.073
transmembrane transport GO:0055085 139 0.072
protein localization GO:0008104 284 0.072
regulation of intracellular signal transduction GO:1902531 236 0.072
proteolysis GO:0006508 192 0.071
catabolic process GO:0009056 409 0.070
protein modification process GO:0036211 438 0.068
regulation of transport GO:0051049 181 0.067
regulation of cellular protein catabolic process GO:1903362 44 0.064
apoptotic process GO:0006915 159 0.063
cellular catabolic process GO:0044248 372 0.059
response to external biotic stimulus GO:0043207 293 0.057
regulation of localization GO:0032879 275 0.056
regulation of protein metabolic process GO:0051246 256 0.054
macromolecule catabolic process GO:0009057 161 0.054
cellular macromolecule catabolic process GO:0044265 136 0.053
establishment of localization in cell GO:0051649 402 0.051
organic substance transport GO:0071702 257 0.049
establishment of protein localization GO:0045184 163 0.049
microtubule organizing center organization GO:0031023 168 0.048
organic substance catabolic process GO:1901575 308 0.048
multicellular organismal aging GO:0010259 140 0.048
regulation of cell death GO:0010941 173 0.048
cell death GO:0008219 279 0.047
protein deubiquitination GO:0016579 17 0.047
cellular protein modification process GO:0006464 438 0.044
sperm individualization GO:0007291 48 0.044
intracellular transport GO:0046907 228 0.042
organelle fission GO:0048285 340 0.042
negative regulation of signaling GO:0023057 219 0.042
mitotic dna integrity checkpoint GO:0044774 75 0.042
growth GO:0040007 359 0.039
spermatogenesis GO:0007283 200 0.039
cell division GO:0051301 248 0.039
defense response to other organism GO:0098542 225 0.038
regulation of defense response GO:0031347 102 0.037
nucleocytoplasmic transport GO:0006913 72 0.036
regulation of programmed cell death GO:0043067 152 0.036
regulation of multi organism process GO:0043900 131 0.036
neurological system process GO:0050877 358 0.035
positive regulation of protein localization to nucleus GO:1900182 21 0.034
regulation of mitotic cell cycle GO:0007346 190 0.034
germarium derived egg chamber formation GO:0007293 101 0.033
single organism nuclear import GO:1902593 51 0.033
regulation of apoptotic process GO:0042981 130 0.033
regulation of meiosis GO:0040020 3 0.033
organophosphate metabolic process GO:0019637 195 0.033
protein localization to nucleus GO:0034504 55 0.033
determination of adult lifespan GO:0008340 137 0.032
signal transduction by phosphorylation GO:0023014 107 0.031
negative regulation of cell communication GO:0010648 223 0.030
chaeta development GO:0022416 97 0.030
protein modification by small protein conjugation GO:0032446 79 0.030
positive regulation of signaling GO:0023056 243 0.030
male gamete generation GO:0048232 201 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
regulation of growth GO:0040008 233 0.028
rna catabolic process GO:0006401 37 0.028
mitochondrion organization GO:0007005 65 0.028
activation of cysteine type endopeptidase activity GO:0097202 17 0.028
negative regulation of response to external stimulus GO:0032102 22 0.028
mapk cascade GO:0000165 107 0.027
protein targeting to nucleus GO:0044744 51 0.027
response to other organism GO:0051707 293 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
cellular protein catabolic process GO:0044257 83 0.027
protein ubiquitination GO:0016567 70 0.026
developmental growth GO:0048589 280 0.026
posttranscriptional regulation of gene expression GO:0010608 145 0.026
regulation of catabolic process GO:0009894 170 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
protein import GO:0017038 55 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
sleep GO:0030431 49 0.026
positive regulation of cell communication GO:0010647 250 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.025
mesenchymal cell differentiation GO:0048762 1 0.025
response to abiotic stimulus GO:0009628 341 0.025
immune system process GO:0002376 347 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
response to bacterium GO:0009617 198 0.025
regulation of nucleocytoplasmic transport GO:0046822 35 0.024
protein maturation GO:0051604 71 0.024
protein processing GO:0016485 68 0.024
cytokinesis GO:0000910 90 0.024
eye development GO:0001654 323 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.023
mrna catabolic process GO:0006402 33 0.023
modification dependent protein catabolic process GO:0019941 78 0.023
aging GO:0007568 143 0.023
chromosome organization GO:0051276 360 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
nucleus organization GO:0006997 45 0.022
intracellular protein transport GO:0006886 104 0.022
regulation of molecular function GO:0065009 217 0.022
intracellular signal transduction GO:0035556 300 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
regulation of protein import into nucleus GO:0042306 28 0.021
regulation of cell division GO:0051302 72 0.021
mrna processing GO:0006397 104 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
single organism catabolic process GO:0044712 228 0.021
centrosome organization GO:0051297 163 0.020
regulation of protein localization to nucleus GO:1900180 29 0.020
nuclear import GO:0051170 51 0.020
synaptic transmission GO:0007268 288 0.020
positive regulation of signal transduction GO:0009967 223 0.020
positive regulation of protein transport GO:0051222 37 0.020
regulation of developmental growth GO:0048638 174 0.020
response to biotic stimulus GO:0009607 294 0.020
regulation of protein catabolic process GO:0042176 55 0.020
endocytosis GO:0006897 310 0.020
g2 dna damage checkpoint GO:0031572 69 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
regulation of protein localization GO:0032880 76 0.019
negative regulation of signal transduction GO:0009968 206 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
kidney development GO:0001822 3 0.019
appendage morphogenesis GO:0035107 397 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
protein catabolic process GO:0030163 101 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
defense response to gram negative bacterium GO:0050829 94 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
peripheral nervous system development GO:0007422 52 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
spermatid differentiation GO:0048515 114 0.018
aromatic compound catabolic process GO:0019439 166 0.018
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.018
single organism biosynthetic process GO:0044711 206 0.018
regulation of notch signaling pathway GO:0008593 100 0.018
regulation of endopeptidase activity GO:0052548 36 0.018
synapse organization GO:0050808 196 0.018
small molecule metabolic process GO:0044281 305 0.017
protein targeting GO:0006605 64 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
nucleotide metabolic process GO:0009117 161 0.017
mitotic cytokinesis GO:0000281 50 0.017
negative regulation of gene expression GO:0010629 387 0.017
oxoacid metabolic process GO:0043436 103 0.017
hindgut morphogenesis GO:0007442 58 0.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.017
cellular protein localization GO:0034613 160 0.017
dna metabolic process GO:0006259 227 0.017
regulation of mapk cascade GO:0043408 92 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
regulation of cellular response to stress GO:0080135 89 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
response to organic substance GO:0010033 284 0.016
vesicle mediated transport GO:0016192 381 0.016
positive regulation of protein import into nucleus GO:0042307 21 0.016
nucleotide excision repair GO:0006289 8 0.016
negative regulation of transcription dna templated GO:0045892 237 0.016
cell cycle phase transition GO:0044770 140 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
regulation of cellular localization GO:0060341 136 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
regulation of establishment of protein localization GO:0070201 61 0.015
regulation of intracellular protein transport GO:0033157 46 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
female gonad development GO:0008585 12 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
rna processing GO:0006396 147 0.015
organic acid metabolic process GO:0006082 103 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
regulation of response to stress GO:0080134 200 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
heterocycle catabolic process GO:0046700 166 0.014
positive regulation of gene expression GO:0010628 290 0.014
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
innate immune response GO:0045087 144 0.014
ion transport GO:0006811 145 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
autophagy GO:0006914 108 0.013
oocyte differentiation GO:0009994 145 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
segmentation GO:0035282 207 0.013
protein localization to organelle GO:0033365 82 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
regulation of phosphorylation GO:0042325 147 0.013
negative regulation of molecular function GO:0044092 51 0.013
rhythmic behavior GO:0007622 76 0.013
protein import into nucleus GO:0006606 51 0.013
regulation of protein transport GO:0051223 57 0.013
negative regulation of developmental process GO:0051093 201 0.013
cell cycle checkpoint GO:0000075 95 0.013
regulation of nuclear division GO:0051783 58 0.013
mitotic spindle organization GO:0007052 220 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
eye morphogenesis GO:0048592 260 0.013
organelle localization GO:0051640 148 0.013
positive regulation of cell death GO:0010942 69 0.013
nephron development GO:0072006 3 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
positive regulation of intracellular protein transport GO:0090316 30 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
protein transmembrane transport GO:0071806 4 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
spindle assembly GO:0051225 80 0.012
response to oxidative stress GO:0006979 86 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
defense response to bacterium GO:0042742 178 0.012
regulation of protein targeting GO:1903533 29 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
response to oxygen containing compound GO:1901700 200 0.012
protein complex biogenesis GO:0070271 201 0.012
dna conformation change GO:0071103 105 0.012
cell proliferation GO:0008283 299 0.012
sensory perception GO:0007600 196 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
negative regulation of cell death GO:0060548 81 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
centrosome duplication GO:0051298 121 0.011
intracellular protein transmembrane transport GO:0065002 4 0.011
spindle organization GO:0007051 253 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of ras protein signal transduction GO:0046579 43 0.011
ras protein signal transduction GO:0007265 88 0.011
erk1 and erk2 cascade GO:0070371 39 0.011
reproductive structure development GO:0048608 74 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
muscle system process GO:0003012 21 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
rna localization GO:0006403 115 0.011
protein phosphorylation GO:0006468 169 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
gland development GO:0048732 191 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
compound eye morphogenesis GO:0001745 249 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of proteolysis GO:0045862 52 0.011
notch signaling pathway GO:0007219 120 0.011
inorganic cation transmembrane transport GO:0098662 61 0.011
ion transmembrane transport GO:0034220 122 0.011
regulation of synapse assembly GO:0051963 94 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
mitochondrial fission GO:0000266 8 0.011
cytoplasmic transport GO:0016482 130 0.011
positive regulation of growth GO:0045927 75 0.011
ubiquitin homeostasis GO:0010992 1 0.011
single organism behavior GO:0044708 391 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
mitotic nuclear division GO:0007067 213 0.011
cellularization GO:0007349 90 0.011
development of primary sexual characteristics GO:0045137 50 0.010
detection of stimulus GO:0051606 156 0.010
response to nutrient levels GO:0031667 114 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
negative regulation of catabolic process GO:0009895 36 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
embryonic pattern specification GO:0009880 174 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
positive regulation of cell cycle GO:0045787 43 0.010

Tpr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 0 0.030
kidney disease DOID:557 0 0.030
disease of anatomical entity DOID:7 0 0.030
urinary system disease DOID:18 0 0.030
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.013