Drosophila melanogaster

143 known processes

Dp (Dmel_CG4654)

DP transcription factor

(Aliases: CG4654,Dmel\CG4654,dDp,l(2)vr10,Dp1,DP1,DmDP,dDP,dDP1,DDP1,TFPD2,49Fk,dp,vr10,DP,l(2)49Fk)

Dp biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.845
regulation of cell cycle g1 s phase transition GO:1902806 23 0.750
negative regulation of rna biosynthetic process GO:1902679 240 0.746
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.742
dna endoreduplication GO:0042023 22 0.727
negative regulation of nucleic acid templated transcription GO:1903507 240 0.697
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.678
cellular response to dna damage stimulus GO:0006974 223 0.632
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.621
negative regulation of rna metabolic process GO:0051253 251 0.606
negative regulation of cellular biosynthetic process GO:0031327 277 0.602
regionalization GO:0003002 416 0.597
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.589
dna damage checkpoint GO:0000077 78 0.575
negative regulation of biosynthetic process GO:0009890 277 0.561
negative regulation of transcription dna templated GO:0045892 237 0.554
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.552
appendage morphogenesis GO:0035107 397 0.541
imaginal disc derived appendage development GO:0048737 399 0.530
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.511
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.509
immune system process GO:0002376 347 0.476
wing disc morphogenesis GO:0007472 344 0.449
intracellular signal transduction GO:0035556 300 0.425
regulation of programmed cell death GO:0043067 152 0.371
tripartite regional subdivision GO:0007351 103 0.370
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.369
imaginal disc derived wing morphogenesis GO:0007476 337 0.362
imaginal disc derived appendage morphogenesis GO:0035114 395 0.351
cell proliferation GO:0008283 299 0.346
cell cycle dna replication GO:0044786 23 0.345
male gamete generation GO:0048232 201 0.344
nurse cell apoptotic process GO:0045476 17 0.342
programmed cell death GO:0012501 257 0.341
negative regulation of cellular metabolic process GO:0031324 382 0.323
oocyte anterior posterior axis specification GO:0007314 72 0.322
axis specification GO:0009798 167 0.317
dna replication GO:0006260 48 0.312
death GO:0016265 284 0.312
maternal determination of anterior posterior axis embryo GO:0008358 74 0.305
transcription from rna polymerase ii promoter GO:0006366 368 0.305
forebrain development GO:0030900 2 0.303
embryonic pattern specification GO:0009880 174 0.300
post embryonic appendage morphogenesis GO:0035120 385 0.298
segmentation GO:0035282 207 0.296
cell maturation GO:0048469 144 0.293
immune response GO:0006955 246 0.284
anterior posterior axis specification GO:0009948 109 0.284
oocyte axis specification GO:0007309 108 0.282
negative regulation of gene expression GO:0010629 387 0.277
central nervous system development GO:0007417 201 0.269
appendage development GO:0048736 401 0.251
single organism cellular localization GO:1902580 180 0.244
positive regulation of rna metabolic process GO:0051254 271 0.231
Mouse
intrinsic apoptotic signaling pathway GO:0097193 16 0.229
oocyte development GO:0048599 124 0.226
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.226
Mouse
oocyte differentiation GO:0009994 145 0.223
embryonic axis specification GO:0000578 107 0.221
regulation of multi organism process GO:0043900 131 0.212
spermatogenesis GO:0007283 200 0.211
g1 s transition of mitotic cell cycle GO:0000082 31 0.210
oocyte construction GO:0007308 112 0.209
regulation of cell proliferation GO:0042127 163 0.207
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 5 0.206
protein localization to chromatin GO:0071168 3 0.195
blastoderm segmentation GO:0007350 159 0.195
response to abiotic stimulus GO:0009628 341 0.190
cell death GO:0008219 279 0.182
cellular macromolecule localization GO:0070727 220 0.181
regulation of cell cycle GO:0051726 291 0.180
negative regulation of cell cycle phase transition GO:1901988 103 0.176
developmental maturation GO:0021700 172 0.173
apoptotic process GO:0006915 159 0.170
regulation of immune system process GO:0002682 176 0.167
positive regulation of macromolecule metabolic process GO:0010604 405 0.166
macromolecular complex assembly GO:0065003 256 0.165
apoptotic process involved in development GO:1902742 20 0.164
negative regulation of cell death GO:0060548 81 0.158
anterior posterior pattern specification GO:0009952 136 0.158
cell cycle checkpoint GO:0000075 95 0.157
organelle fission GO:0048285 340 0.150
regulation of reproductive process GO:2000241 54 0.149
apoptotic signaling pathway GO:0097190 27 0.141
antimicrobial humoral response GO:0019730 99 0.141
regulation of cell cycle process GO:0010564 181 0.132
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.131
anterior posterior axis specification embryo GO:0008595 103 0.130
dendrite development GO:0016358 204 0.129
phosphorylation GO:0016310 294 0.125
response to other organism GO:0051707 293 0.125
response to organic substance GO:0010033 284 0.121
regulation of mitotic cell cycle GO:0007346 190 0.120
negative regulation of programmed cell death GO:0043069 72 0.118
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.115
posttranscriptional regulation of gene expression GO:0010608 145 0.112
dna integrity checkpoint GO:0031570 81 0.111
protein localization to organelle GO:0033365 82 0.111
mitotic nuclear division GO:0007067 213 0.110
positive regulation of programmed cell death GO:0043068 62 0.104
negative regulation of cell cycle process GO:0010948 109 0.104
dna metabolic process GO:0006259 227 0.104
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.103
response to external biotic stimulus GO:0043207 293 0.103
regulation of apoptotic process GO:0042981 130 0.103
nuclear division GO:0000280 332 0.102
regulation of mitotic cell cycle phase transition GO:1901990 130 0.101
regulation of cell death GO:0010941 173 0.099
response to oxygen containing compound GO:1901700 200 0.099
positive regulation of multi organism process GO:0043902 40 0.099
lipid metabolic process GO:0006629 121 0.098
positive regulation of gene expression GO:0010628 290 0.097
brain development GO:0007420 120 0.095
protein modification process GO:0036211 438 0.094
dendrite morphogenesis GO:0048813 199 0.094
cell cycle phase transition GO:0044770 140 0.092
positive regulation of cell differentiation GO:0045597 64 0.089
rna processing GO:0006396 147 0.089
cellular protein modification process GO:0006464 438 0.088
single organism biosynthetic process GO:0044711 206 0.086
positive regulation of cell death GO:0010942 69 0.086
ovarian follicle cell development GO:0030707 248 0.084
response to endogenous stimulus GO:0009719 119 0.084
positive regulation of developmental process GO:0051094 143 0.082
protein complex biogenesis GO:0070271 201 0.082
carbohydrate derivative biosynthetic process GO:1901137 85 0.082
dorsal ventral axis specification GO:0009950 66 0.081
dorsal ventral pattern formation GO:0009953 133 0.080
regulation of dna replication GO:0006275 13 0.075
mitotic g2 m transition checkpoint GO:0044818 70 0.072
negative regulation of apoptotic process GO:0043066 63 0.070
positive regulation of cell proliferation GO:0008284 47 0.069
negative regulation of cell cycle GO:0045786 116 0.067
negative regulation of response to stimulus GO:0048585 258 0.066
regulation of cell differentiation GO:0045595 302 0.066
mitotic cell cycle phase transition GO:0044772 138 0.066
cell type specific apoptotic process GO:0097285 38 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.065
Mouse
protein complex assembly GO:0006461 200 0.065
oocyte dorsal ventral axis specification GO:0007310 34 0.064
cell cycle g1 s phase transition GO:0044843 31 0.064
response to biotic stimulus GO:0009607 294 0.064
mitotic dna integrity checkpoint GO:0044774 75 0.064
cell motility GO:0048870 251 0.063
protein localization GO:0008104 284 0.062
negative regulation of mitotic cell cycle GO:0045930 109 0.060
cellular protein localization GO:0034613 160 0.060
body morphogenesis GO:0010171 2 0.059
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.057
epithelial cell differentiation GO:0030855 322 0.056
organophosphate metabolic process GO:0019637 195 0.056
positive regulation of apoptotic process GO:0043065 47 0.056
axon development GO:0061564 297 0.055
response to decreased oxygen levels GO:0036293 58 0.054
mitotic g2 dna damage checkpoint GO:0007095 69 0.053
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.053
g2 dna damage checkpoint GO:0031572 69 0.053
mitotic dna damage checkpoint GO:0044773 74 0.053
columnar cuboidal epithelial cell development GO:0002066 249 0.052
chromosome organization GO:0051276 360 0.052
regulation of phosphate metabolic process GO:0019220 210 0.052
positive regulation of biosynthetic process GO:0009891 316 0.051
Mouse
pole plasm oskar mrna localization GO:0045451 46 0.051
regulation of growth GO:0040008 233 0.050
response to growth factor GO:0070848 31 0.050
microtubule organizing center organization GO:0031023 168 0.049
positive regulation of nucleic acid templated transcription GO:1903508 266 0.049
Mouse
growth GO:0040007 359 0.047
positive regulation of response to stimulus GO:0048584 323 0.046
rna localization GO:0006403 115 0.046
negative regulation of signaling GO:0023057 219 0.046
axon guidance GO:0007411 233 0.043
pole plasm mrna localization GO:0019094 49 0.043
protein phosphorylation GO:0006468 169 0.041
enzyme linked receptor protein signaling pathway GO:0007167 179 0.041
cellular response to endogenous stimulus GO:0071495 80 0.040
cell migration GO:0016477 238 0.040
positive regulation of reproductive process GO:2000243 7 0.040
vesicle mediated transport GO:0016192 381 0.040
cellular lipid metabolic process GO:0044255 83 0.039
localization of cell GO:0051674 257 0.039
negative regulation of dna metabolic process GO:0051053 12 0.039
regulation of phosphorylation GO:0042325 147 0.038
cellular response to chemical stimulus GO:0070887 199 0.037
cellular protein complex assembly GO:0043623 71 0.037
cellular macromolecular complex assembly GO:0034622 153 0.036
digestive tract morphogenesis GO:0048546 127 0.035
regulation of developmental growth GO:0048638 174 0.035
neuron projection guidance GO:0097485 241 0.035
cell division GO:0051301 248 0.035
regulation of transferase activity GO:0051338 58 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.034
positive regulation of signaling GO:0023056 243 0.034
regulation of catalytic activity GO:0050790 185 0.033
regulation of molecular function GO:0065009 217 0.033
pole plasm assembly GO:0007315 61 0.033
negative regulation of dna replication GO:0008156 7 0.033
epithelial cell development GO:0002064 274 0.033
positive regulation of cellular component organization GO:0051130 156 0.032
organelle assembly GO:0070925 198 0.032
axonogenesis GO:0007409 290 0.032
carbohydrate derivative metabolic process GO:1901135 217 0.032
response to radiation GO:0009314 155 0.032
eggshell formation GO:0030703 105 0.032
digestive system development GO:0055123 149 0.031
positive regulation of multicellular organismal process GO:0051240 143 0.031
covalent chromatin modification GO:0016569 106 0.030
spindle organization GO:0007051 253 0.030
cytoplasm organization GO:0007028 64 0.030
embryo development ending in birth or egg hatching GO:0009792 152 0.030
mitotic spindle organization GO:0007052 220 0.030
regulation of localization GO:0032879 275 0.030
chromatin modification GO:0016568 147 0.029
digestive tract development GO:0048565 149 0.029
rna splicing GO:0008380 83 0.029
chromosome segregation GO:0007059 157 0.028
taxis GO:0042330 304 0.028
organic hydroxy compound metabolic process GO:1901615 83 0.028
mitotic sister chromatid segregation GO:0000070 87 0.028
compound eye morphogenesis GO:0001745 249 0.028
pole plasm rna localization GO:0007316 52 0.028
regulation of protein localization GO:0032880 76 0.027
organophosphate biosynthetic process GO:0090407 46 0.027
eggshell chorion assembly GO:0007306 66 0.026
response to acid chemical GO:0001101 25 0.025
tube development GO:0035295 244 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
epidermal growth factor receptor signaling pathway GO:0007173 58 0.025
positive regulation of signal transduction GO:0009967 223 0.024
muscle tissue development GO:0060537 30 0.024
spindle assembly GO:0051225 80 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
Mouse
negative regulation of immune system process GO:0002683 50 0.024
negative regulation of cell communication GO:0010648 223 0.023
cellular response to oxygen containing compound GO:1901701 79 0.023
determination of adult lifespan GO:0008340 137 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
regulation of gene expression epigenetic GO:0040029 128 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
ras protein signal transduction GO:0007265 88 0.023
small molecule metabolic process GO:0044281 305 0.023
mrna metabolic process GO:0016071 124 0.023
eye development GO:0001654 323 0.022
innate immune response GO:0045087 144 0.022
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.021
histone modification GO:0016570 106 0.021
regulation of cell development GO:0060284 215 0.021
cellular response to decreased oxygen levels GO:0036294 30 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
regulation of response to external stimulus GO:0032101 115 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
regulation of cellular localization GO:0060341 136 0.020
response to alcohol GO:0097305 95 0.020
phagocytosis GO:0006909 215 0.020
reproductive structure development GO:0048608 74 0.019
chorion containing eggshell formation GO:0007304 105 0.019
negative regulation of signal transduction GO:0009968 206 0.019
regulation of response to stress GO:0080134 200 0.019
response to oxygen levels GO:0070482 59 0.019
intracellular mrna localization GO:0008298 66 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
Mouse
peptidyl lysine acetylation GO:0018394 39 0.018
organic substance catabolic process GO:1901575 308 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
cellular response to organic substance GO:0071310 132 0.018
response to light stimulus GO:0009416 124 0.018
sex differentiation GO:0007548 81 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
regulation of organelle organization GO:0033043 196 0.018
regulation of kinase activity GO:0043549 53 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
internal peptidyl lysine acetylation GO:0018393 38 0.017
meiotic cell cycle GO:0051321 171 0.017
establishment of protein localization GO:0045184 163 0.017
nucleosome organization GO:0034728 59 0.016
chemotaxis GO:0006935 249 0.016
endocytosis GO:0006897 310 0.016
response to temperature stimulus GO:0009266 106 0.016
mrna splicing via spliceosome GO:0000398 73 0.016
open tracheal system development GO:0007424 204 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
Mouse
positive regulation of cell communication GO:0010647 250 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
synaptic transmission GO:0007268 288 0.016
chromatin organization GO:0006325 207 0.016
peptidyl lysine modification GO:0018205 57 0.016
response to oxidative stress GO:0006979 86 0.015
response to lipid GO:0033993 38 0.015
ameboidal type cell migration GO:0001667 151 0.015
sensory organ morphogenesis GO:0090596 260 0.015
endomembrane system organization GO:0010256 119 0.015
gene silencing by rna GO:0031047 57 0.015
oxoacid metabolic process GO:0043436 103 0.015
sister chromatid segregation GO:0000819 92 0.015
positive regulation of molecular function GO:0044093 136 0.015
male sex differentiation GO:0046661 25 0.015
protein acylation GO:0043543 42 0.015
regulation of cellular component size GO:0032535 98 0.015
cellular catabolic process GO:0044248 372 0.015
negative regulation of developmental process GO:0051093 201 0.014
rna splicing via transesterification reactions GO:0000375 73 0.014
development of primary sexual characteristics GO:0045137 50 0.014
erbb signaling pathway GO:0038127 58 0.014
regulation of defense response GO:0031347 102 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
cellular carbohydrate metabolic process GO:0044262 22 0.014
regulation of protein modification process GO:0031399 112 0.014
response to organic cyclic compound GO:0014070 89 0.014
telencephalon development GO:0021537 2 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
cilium morphogenesis GO:0060271 39 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
Mouse
mrna processing GO:0006397 104 0.013
larval development GO:0002164 104 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
developmental programmed cell death GO:0010623 138 0.013
cellular response to oxygen levels GO:0071453 30 0.012
muscle structure development GO:0061061 224 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
regulation of chromosome organization GO:0033044 64 0.012
single organism behavior GO:0044708 391 0.012
mapk cascade GO:0000165 107 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
regulation of nervous system development GO:0051960 248 0.012
regulation of immune response GO:0050776 118 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
peptidyl amino acid modification GO:0018193 105 0.012
embryonic morphogenesis GO:0048598 206 0.012
establishment of localization in cell GO:0051649 402 0.012
negative regulation of growth GO:0045926 84 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
internal protein amino acid acetylation GO:0006475 38 0.012
response to lipopolysaccharide GO:0032496 4 0.012
nuclear transport GO:0051169 72 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
regulation of protein metabolic process GO:0051246 256 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
tube morphogenesis GO:0035239 191 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
cellular response to hypoxia GO:0071456 28 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
cellular response to acid chemical GO:0071229 8 0.011
defense response to other organism GO:0098542 225 0.011
protein dna complex subunit organization GO:0071824 86 0.011
chromatin remodeling GO:0006338 72 0.011
nuclear import GO:0051170 51 0.011
chemosensory behavior GO:0007635 106 0.011
rrna processing GO:0006364 3 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
regulation of chromosome segregation GO:0051983 32 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
spermatid differentiation GO:0048515 114 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
cilium organization GO:0044782 41 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
protein transport GO:0015031 155 0.010
membrane organization GO:0061024 112 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
cell growth GO:0016049 108 0.010
erk1 and erk2 cascade GO:0070371 39 0.010

Dp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.011