Drosophila melanogaster

43 known processes

CG4673 (Dmel_CG4673)

CG4673 gene product from transcript CG4673-RB

(Aliases: dNp14,npl4,NPL4,Dmel\CG4673)

CG4673 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.569
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.339
modification dependent protein catabolic process GO:0019941 78 0.302
response to external biotic stimulus GO:0043207 293 0.253
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.240
response to other organism GO:0051707 293 0.235
modification dependent macromolecule catabolic process GO:0043632 79 0.229
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.221
cellular catabolic process GO:0044248 372 0.179
spindle organization GO:0007051 253 0.167
regulation of catabolic process GO:0009894 170 0.162
response to light stimulus GO:0009416 124 0.149
regulation of proteolysis GO:0030162 87 0.142
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.139
positive regulation of nucleic acid templated transcription GO:1903508 266 0.134
regulation of protein metabolic process GO:0051246 256 0.130
positive regulation of rna biosynthetic process GO:1902680 266 0.123
mitotic spindle organization GO:0007052 220 0.123
homeostatic process GO:0042592 199 0.123
ubiquitin dependent protein catabolic process GO:0006511 78 0.121
catabolic process GO:0009056 409 0.116
proteolysis GO:0006508 192 0.113
macromolecule catabolic process GO:0009057 161 0.111
proteasomal protein catabolic process GO:0010498 59 0.111
negative regulation of developmental process GO:0051093 201 0.109
positive regulation of transcription dna templated GO:0045893 266 0.106
positive regulation of cellular biosynthetic process GO:0031328 316 0.102
localization of cell GO:0051674 257 0.101
cellular response to dna damage stimulus GO:0006974 223 0.097
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.097
positive regulation of gene expression GO:0010628 290 0.095
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.095
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.091
regulation of cell cycle GO:0051726 291 0.091
positive regulation of proteolysis GO:0045862 52 0.088
regulation of cellular component biogenesis GO:0044087 201 0.088
positive regulation of cellular protein metabolic process GO:0032270 118 0.088
organic substance catabolic process GO:1901575 308 0.087
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.087
response to abiotic stimulus GO:0009628 341 0.084
response to biotic stimulus GO:0009607 294 0.084
organic substance transport GO:0071702 257 0.081
multicellular organismal aging GO:0010259 140 0.079
positive regulation of protein metabolic process GO:0051247 128 0.078
negative regulation of response to stimulus GO:0048585 258 0.078
regulation of cellular protein metabolic process GO:0032268 243 0.077
transcription from rna polymerase ii promoter GO:0006366 368 0.077
cellular macromolecule catabolic process GO:0044265 136 0.075
central nervous system development GO:0007417 201 0.074
regulation of cellular catabolic process GO:0031329 157 0.074
aging GO:0007568 143 0.071
single organism cellular localization GO:1902580 180 0.068
positive regulation of rna metabolic process GO:0051254 271 0.067
regulation of response to stress GO:0080134 200 0.065
single organism intracellular transport GO:1902582 207 0.064
protein localization GO:0008104 284 0.064
regulation of organelle organization GO:0033043 196 0.063
organonitrogen compound metabolic process GO:1901564 318 0.063
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.062
intracellular transport GO:0046907 228 0.061
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.061
positive regulation of developmental process GO:0051094 143 0.061
cell migration GO:0016477 238 0.059
vesicle mediated transport GO:0016192 381 0.057
regulation of proteasomal protein catabolic process GO:0061136 39 0.052
chromatin assembly or disassembly GO:0006333 52 0.052
dna metabolic process GO:0006259 227 0.048
protein catabolic process GO:0030163 101 0.047
posttranscriptional regulation of gene expression GO:0010608 145 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.046
forebrain development GO:0030900 2 0.045
response to virus GO:0009615 28 0.045
positive regulation of response to stimulus GO:0048584 323 0.045
cellular response to external stimulus GO:0071496 66 0.045
double strand break repair GO:0006302 26 0.045
mitochondrion organization GO:0007005 65 0.043
cellular protein catabolic process GO:0044257 83 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
negative regulation of rna metabolic process GO:0051253 251 0.041
negative regulation of transcription dna templated GO:0045892 237 0.040
regulation of mitotic cell cycle GO:0007346 190 0.040
lipid metabolic process GO:0006629 121 0.039
negative regulation of gene expression GO:0010629 387 0.039
negative regulation of rna biosynthetic process GO:1902679 240 0.039
appendage morphogenesis GO:0035107 397 0.039
epithelial cell differentiation GO:0030855 322 0.039
death GO:0016265 284 0.038
negative regulation of biosynthetic process GO:0009890 277 0.038
single organism catabolic process GO:0044712 228 0.038
regulation of defense response GO:0031347 102 0.037
protein modification by small protein conjugation or removal GO:0070647 106 0.037
determination of adult lifespan GO:0008340 137 0.037
negative regulation of nucleic acid templated transcription GO:1903507 240 0.036
wing disc morphogenesis GO:0007472 344 0.036
regulation of cell differentiation GO:0045595 302 0.035
neurological system process GO:0050877 358 0.035
brain development GO:0007420 120 0.035
protein deubiquitination GO:0016579 17 0.035
establishment of localization in cell GO:0051649 402 0.034
response to radiation GO:0009314 155 0.034
regulation of immune system process GO:0002682 176 0.034
regulation of cellular protein catabolic process GO:1903362 44 0.034
defense response GO:0006952 300 0.034
developmental maturation GO:0021700 172 0.034
autophagy GO:0006914 108 0.033
segmentation GO:0035282 207 0.033
eye morphogenesis GO:0048592 260 0.033
immune system process GO:0002376 347 0.033
regulation of cellular response to stress GO:0080135 89 0.032
translation GO:0006412 69 0.032
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
cell division GO:0051301 248 0.032
telencephalon development GO:0021537 2 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
positive regulation of cellular catabolic process GO:0031331 95 0.030
protein modification by small protein removal GO:0070646 28 0.030
positive regulation of signal transduction GO:0009967 223 0.030
protein transport GO:0015031 155 0.030
positive regulation of catabolic process GO:0009896 105 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
small molecule metabolic process GO:0044281 305 0.029
regulation of cell cycle process GO:0010564 181 0.029
cell proliferation GO:0008283 299 0.029
positive regulation of protein catabolic process GO:0045732 34 0.028
eye development GO:0001654 323 0.028
neutral lipid biosynthetic process GO:0046460 2 0.028
regulation of lipid metabolic process GO:0019216 15 0.027
defense response to bacterium GO:0042742 178 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
negative regulation of multicellular organismal process GO:0051241 142 0.027
endocytosis GO:0006897 310 0.027
protein depolymerization GO:0051261 31 0.027
skeletal muscle organ development GO:0060538 48 0.027
response to organic substance GO:0010033 284 0.027
negative regulation of signaling GO:0023057 219 0.026
cellular response to oxidative stress GO:0034599 28 0.026
protein modification process GO:0036211 438 0.026
positive regulation of lipid metabolic process GO:0045834 4 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
oocyte development GO:0048599 124 0.025
response to starvation GO:0042594 97 0.025
intracellular signal transduction GO:0035556 300 0.025
phosphorylation GO:0016310 294 0.025
gene silencing by rna GO:0031047 57 0.024
cellular lipid metabolic process GO:0044255 83 0.024
jak stat cascade GO:0007259 49 0.024
response to extracellular stimulus GO:0009991 116 0.024
negative regulation of cell communication GO:0010648 223 0.024
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.024
response to nutrient levels GO:0031667 114 0.023
defense response to other organism GO:0098542 225 0.023
chromosome organization GO:0051276 360 0.023
compound eye development GO:0048749 307 0.023
antimicrobial peptide production GO:0002775 46 0.023
regulation of cell death GO:0010941 173 0.023
regulation of autophagy GO:0010506 62 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
regulation of multi organism process GO:0043900 131 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
organelle fission GO:0048285 340 0.021
apoptotic process GO:0006915 159 0.021
positive regulation of cellular protein catabolic process GO:1903364 24 0.021
regulation of dna metabolic process GO:0051052 34 0.021
cellular macromolecule localization GO:0070727 220 0.021
protein localization to organelle GO:0033365 82 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.021
positive regulation of cell communication GO:0010647 250 0.020
ubiquitin homeostasis GO:0010992 1 0.020
regulation of neurogenesis GO:0050767 158 0.020
single organism behavior GO:0044708 391 0.020
phagocytosis GO:0006909 215 0.020
cell maturation GO:0048469 144 0.020
humoral immune response GO:0006959 117 0.020
compound eye photoreceptor development GO:0042051 78 0.020
stem cell differentiation GO:0048863 117 0.020
cell death GO:0008219 279 0.020
organic acid metabolic process GO:0006082 103 0.020
rhabdomere development GO:0042052 38 0.020
triglyceride catabolic process GO:0019433 3 0.019
programmed cell death GO:0012501 257 0.019
cytoplasmic transport GO:0016482 130 0.019
appendage development GO:0048736 401 0.019
head development GO:0060322 135 0.019
regulation of growth GO:0040008 233 0.019
monocarboxylic acid transport GO:0015718 3 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
establishment of protein localization GO:0045184 163 0.018
neutral lipid catabolic process GO:0046461 3 0.018
lipid localization GO:0010876 54 0.018
striated muscle tissue development GO:0014706 27 0.018
embryonic organ development GO:0048568 50 0.018
phosphatidylinositol mediated signaling GO:0048015 4 0.018
gene silencing GO:0016458 138 0.018
nuclear division GO:0000280 332 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.017
negative regulation of translation GO:0017148 28 0.017
carbohydrate metabolic process GO:0005975 82 0.017
response to heat GO:0009408 63 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
ovarian follicle cell development GO:0030707 248 0.017
cellular protein localization GO:0034613 160 0.017
antimicrobial humoral response GO:0019730 99 0.017
anatomical structure homeostasis GO:0060249 97 0.016
nitrogen compound transport GO:0071705 85 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
nucleotide catabolic process GO:0009166 109 0.016
negative regulation of growth GO:0045926 84 0.016
organophosphate metabolic process GO:0019637 195 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
negative regulation of endopeptidase activity GO:0010951 11 0.016
secretion GO:0046903 109 0.016
regulation of developmental growth GO:0048638 174 0.016
protein complex biogenesis GO:0070271 201 0.016
vesicle organization GO:0016050 44 0.016
chromatin modification GO:0016568 147 0.016
mitotic cytokinesis GO:0000281 50 0.016
protein complex disassembly GO:0043241 36 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
regulation of response to external stimulus GO:0032101 115 0.016
mitotic spindle elongation GO:0000022 81 0.016
regulation of transport GO:0051049 181 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
regulation of response to biotic stimulus GO:0002831 63 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
meiotic cell cycle GO:0051321 171 0.015
regulation of protein catabolic process GO:0042176 55 0.015
regulation of nervous system development GO:0051960 248 0.015
mesenchymal cell differentiation GO:0048762 1 0.015
associative learning GO:0008306 65 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
regulation of catalytic activity GO:0050790 185 0.015
immune effector process GO:0002252 98 0.015
positive regulation of catalytic activity GO:0043085 118 0.014
cellular response to nutrient levels GO:0031669 62 0.014
gliogenesis GO:0042063 80 0.014
regulation of cell development GO:0060284 215 0.014
cellularization GO:0007349 90 0.014
negative regulation of signal transduction GO:0009968 206 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
regulation of localization GO:0032879 275 0.014
regulation of response to oxidative stress GO:1902882 4 0.014
nucleotide metabolic process GO:0009117 161 0.014
dna repair GO:0006281 54 0.014
lipid homeostasis GO:0055088 33 0.014
developmental programmed cell death GO:0010623 138 0.014
chaeta development GO:0022416 97 0.014
response to bacterium GO:0009617 198 0.014
positive regulation of lipid catabolic process GO:0050996 1 0.014
cellular response to extracellular stimulus GO:0031668 64 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
telomere organization GO:0032200 21 0.013
dna packaging GO:0006323 91 0.013
pole plasm assembly GO:0007315 61 0.013
protein complex assembly GO:0006461 200 0.013
intracellular protein transport GO:0006886 104 0.013
muscle tissue development GO:0060537 30 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
response to oxidative stress GO:0006979 86 0.013
oocyte anterior posterior axis specification GO:0007314 72 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
regulation of chromosome organization GO:0033044 64 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
macromolecular complex assembly GO:0065003 256 0.013
protein import into nucleus GO:0006606 51 0.013
regulation of immune response GO:0050776 118 0.013
single organism biosynthetic process GO:0044711 206 0.013
chromatin organization GO:0006325 207 0.013
membrane organization GO:0061024 112 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.013
response to hexose GO:0009746 3 0.013
chemosensory behavior GO:0007635 106 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
axon development GO:0061564 297 0.012
lipid modification GO:0030258 24 0.012
chemotaxis GO:0006935 249 0.012
organelle assembly GO:0070925 198 0.012
positive regulation of cell proliferation GO:0008284 47 0.012
cell motility GO:0048870 251 0.012
regulation of dna recombination GO:0000018 4 0.012
meiotic nuclear division GO:0007126 151 0.012
spermatogenesis GO:0007283 200 0.012
taxis GO:0042330 304 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
connective tissue development GO:0061448 3 0.012
cellular response to starvation GO:0009267 61 0.012
ion transport GO:0006811 145 0.012
immune response GO:0006955 246 0.012
instar larval development GO:0002168 55 0.012
regulation of protein modification process GO:0031399 112 0.012
biological adhesion GO:0022610 138 0.012
heterocycle catabolic process GO:0046700 166 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.012
larval development GO:0002164 104 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
neuron projection guidance GO:0097485 241 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
heart development GO:0007507 82 0.011
male gamete generation GO:0048232 201 0.011
histone modification GO:0016570 106 0.011
endomembrane system organization GO:0010256 119 0.011
inositol lipid mediated signaling GO:0048017 4 0.011
response to organophosphorus GO:0046683 2 0.011
regionalization GO:0003002 416 0.011
regulation of immune effector process GO:0002697 52 0.011
macroautophagy GO:0016236 42 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
protein targeting GO:0006605 64 0.011
negative regulation of notch signaling pathway GO:0045746 41 0.011
negative regulation of cell cycle GO:0045786 116 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
camera type eye development GO:0043010 4 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
cellular homeostasis GO:0019725 80 0.011
glycerolipid catabolic process GO:0046503 3 0.011
response to uv GO:0009411 24 0.011
reproductive system development GO:0061458 74 0.011
lipid biosynthetic process GO:0008610 46 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
maternal determination of anterior posterior axis embryo GO:0008358 74 0.010
regulation of anatomical structure size GO:0090066 163 0.010
nicotinamide nucleotide metabolic process GO:0046496 2 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
optokinetic behavior GO:0007634 3 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
dna conformation change GO:0071103 105 0.010
intracellular protein transmembrane transport GO:0065002 4 0.010
regulation of protein complex assembly GO:0043254 42 0.010
covalent chromatin modification GO:0016569 106 0.010
nuclear transport GO:0051169 72 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
ras protein signal transduction GO:0007265 88 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.010

CG4673 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.063
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
inherited metabolic disorder DOID:655 0 0.014
organ system cancer DOID:0050686 0 0.013
disease of anatomical entity DOID:7 0 0.011