Drosophila melanogaster

113 known processes

l(2)gd1 (Dmel_CG4713)

lethal (2) giant discs 1

(Aliases: l[[2]]gd,l(2)SH0495,Dmel\CG4713,lgd,l(2)gd,gd,SH495,CG4713,l(2)SH2 0495,l(2)giant disc)

l(2)gd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell communication GO:0010648 223 0.648
epithelial cell development GO:0002064 274 0.578
cell division GO:0051301 248 0.536
regulation of epithelial cell proliferation GO:0050678 4 0.484
axon development GO:0061564 297 0.373
developmental growth GO:0048589 280 0.358
appendage morphogenesis GO:0035107 397 0.338
cell maturation GO:0048469 144 0.324
embryonic pattern specification GO:0009880 174 0.277
negative regulation of response to stimulus GO:0048585 258 0.269
anterior posterior pattern specification GO:0009952 136 0.257
cell motility GO:0048870 251 0.244
negative regulation of transcription dna templated GO:0045892 237 0.242
stem cell development GO:0048864 79 0.214
segmentation GO:0035282 207 0.214
axonogenesis GO:0007409 290 0.194
post embryonic appendage morphogenesis GO:0035120 385 0.191
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.191
imaginal disc derived appendage morphogenesis GO:0035114 395 0.190
imaginal disc pattern formation GO:0007447 91 0.184
epithelial cell differentiation GO:0030855 322 0.183
endosomal transport GO:0016197 44 0.180
eye development GO:0001654 323 0.173
positive regulation of gene expression GO:0010628 290 0.171
compound eye photoreceptor cell differentiation GO:0001751 140 0.169
enzyme linked receptor protein signaling pathway GO:0007167 179 0.169
imaginal disc growth GO:0007446 37 0.165
negative regulation of cellular metabolic process GO:0031324 382 0.164
erbb signaling pathway GO:0038127 58 0.161
blastoderm segmentation GO:0007350 159 0.161
growth GO:0040007 359 0.158
protein modification process GO:0036211 438 0.152
vesicle mediated transport GO:0016192 381 0.148
negative regulation of signaling GO:0023057 219 0.148
negative regulation of biosynthetic process GO:0009890 277 0.137
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.137
cellular component assembly involved in morphogenesis GO:0010927 151 0.127
negative regulation of cellular biosynthetic process GO:0031327 277 0.127
mesenchymal cell differentiation GO:0048762 1 0.125
embryonic axis specification GO:0000578 107 0.123
localization of cell GO:0051674 257 0.119
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.118
positive regulation of rna metabolic process GO:0051254 271 0.114
negative regulation of signal transduction GO:0009968 206 0.108
regionalization GO:0003002 416 0.105
regulation of nervous system development GO:0051960 248 0.105
eye photoreceptor cell differentiation GO:0001754 145 0.104
anterior posterior axis specification GO:0009948 109 0.094
adult locomotory behavior GO:0008344 76 0.093
cellular protein modification process GO:0006464 438 0.091
appendage development GO:0048736 401 0.089
eye morphogenesis GO:0048592 260 0.089
compound eye morphogenesis GO:0001745 249 0.083
establishment or maintenance of cell polarity GO:0007163 167 0.082
tripartite regional subdivision GO:0007351 103 0.080
regulation of neuroblast proliferation GO:1902692 34 0.080
neuron fate commitment GO:0048663 50 0.078
organonitrogen compound metabolic process GO:1901564 318 0.077
eye photoreceptor cell fate commitment GO:0042706 37 0.074
ovarian follicle cell development GO:0030707 248 0.074
phosphorylation GO:0016310 294 0.072
epidermal growth factor receptor signaling pathway GO:0007173 58 0.067
tissue death GO:0016271 102 0.066
imaginal disc derived appendage development GO:0048737 399 0.063
negative regulation of rna biosynthetic process GO:1902679 240 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.060
wing disc morphogenesis GO:0007472 344 0.059
homeostatic process GO:0042592 199 0.058
tissue morphogenesis GO:0048729 297 0.058
mesenchymal cell development GO:0014031 1 0.057
negative regulation of gene expression GO:0010629 387 0.056
negative regulation of rna metabolic process GO:0051253 251 0.055
establishment of cell polarity GO:0030010 40 0.052
compound eye development GO:0048749 307 0.050
chemotaxis GO:0006935 249 0.050
regulation of reproductive process GO:2000241 54 0.049
lateral inhibition GO:0046331 206 0.048
segment polarity determination GO:0007367 25 0.048
mating behavior GO:0007617 106 0.048
wing disc pattern formation GO:0035222 66 0.047
regulation of imaginal disc growth GO:0045570 26 0.047
taxis GO:0042330 304 0.047
muscle fiber development GO:0048747 12 0.046
immune system process GO:0002376 347 0.046
dendrite morphogenesis GO:0048813 199 0.045
regulation of hemocyte proliferation GO:0035206 37 0.044
muscle organ development GO:0007517 127 0.043
regulation of multicellular organismal development GO:2000026 414 0.043
notch signaling pathway GO:0007219 120 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.041
rhythmic process GO:0048511 106 0.041
photoreceptor cell differentiation GO:0046530 170 0.041
feeding behavior GO:0007631 50 0.040
axon guidance GO:0007411 233 0.039
columnar cuboidal epithelial cell development GO:0002066 249 0.038
positive energy taxis GO:0052128 3 0.038
regulation of cell differentiation GO:0045595 302 0.037
smoothened signaling pathway GO:0007224 49 0.037
multi multicellular organism process GO:0044706 123 0.037
negative regulation of epithelial cell proliferation GO:0050680 4 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
embryonic development via the syncytial blastoderm GO:0001700 148 0.035
regulation of cell development GO:0060284 215 0.035
circulatory system process GO:0003013 37 0.035
regulation of epithelial cell differentiation GO:0030856 4 0.034
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.034
anterior posterior axis specification embryo GO:0008595 103 0.034
regulation of erbb signaling pathway GO:1901184 42 0.034
catabolic process GO:0009056 409 0.033
macromolecule catabolic process GO:0009057 161 0.033
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
protein modification by small protein conjugation GO:0032446 79 0.032
eggshell chorion assembly GO:0007306 66 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
cell migration GO:0016477 238 0.031
wing disc dorsal ventral pattern formation GO:0048190 47 0.031
cell death GO:0008219 279 0.031
response to extracellular stimulus GO:0009991 116 0.031
locomotory behavior GO:0007626 176 0.031
phagocytosis GO:0006909 215 0.030
protein ubiquitination GO:0016567 70 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
stem cell differentiation GO:0048863 117 0.029
axis specification GO:0009798 167 0.028
chaeta development GO:0022416 97 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.027
regulation of viral genome replication GO:0045069 4 0.027
regulation of cell proliferation GO:0042127 163 0.026
imaginal disc derived leg morphogenesis GO:0007480 80 0.026
connective tissue development GO:0061448 3 0.026
cell fate determination GO:0001709 91 0.026
developmental maturation GO:0021700 172 0.025
response to organic substance GO:0010033 284 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
positive regulation of nucleic acid templated transcription GO:1903508 266 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.024
sensory organ morphogenesis GO:0090596 260 0.024
regulation of multi organism process GO:0043900 131 0.023
programmed cell death GO:0012501 257 0.023
dorsal ventral pattern formation GO:0009953 133 0.022
oocyte microtubule cytoskeleton organization GO:0016325 35 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.021
stem cell maintenance GO:0019827 67 0.021
organic substance catabolic process GO:1901575 308 0.020
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.020
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.019
pupal development GO:0035209 11 0.018
epidermal cell differentiation GO:0009913 51 0.018
chorion containing eggshell formation GO:0007304 105 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
leg disc morphogenesis GO:0007478 80 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.017
cellular lipid metabolic process GO:0044255 83 0.017
regulation of programmed cell death GO:0043067 152 0.016
cellular amine metabolic process GO:0044106 12 0.016
cellular response to growth factor stimulus GO:0071363 30 0.016
embryonic morphogenesis GO:0048598 206 0.016
morphogenesis of follicular epithelium GO:0016333 36 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
camera type eye development GO:0043010 4 0.015
neuroblast differentiation GO:0014016 29 0.015
regulation of neurogenesis GO:0050767 158 0.015
chaeta morphogenesis GO:0008407 42 0.015
regulation of developmental growth GO:0048638 174 0.014
regulation of cell death GO:0010941 173 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
cell proliferation GO:0008283 299 0.014
adult behavior GO:0030534 137 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.014
cellular protein catabolic process GO:0044257 83 0.014
negative regulation of developmental process GO:0051093 201 0.013
regulation of neuron differentiation GO:0045664 103 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
oocyte anterior posterior axis specification GO:0007314 72 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
positive regulation of signal transduction GO:0009967 223 0.013
regulation of growth GO:0040008 233 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
dorsal appendage formation GO:0046843 47 0.012
regulation of cell cycle process GO:0010564 181 0.012
intracellular signal transduction GO:0035556 300 0.012
histolysis GO:0007559 102 0.012
regulation of phosphorylation GO:0042325 147 0.012
epidermis development GO:0008544 65 0.012
renal tubule development GO:0061326 64 0.012
amine metabolic process GO:0009308 12 0.012
multicellular organismal aging GO:0010259 140 0.012
head development GO:0060322 135 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
negative regulation of cell differentiation GO:0045596 143 0.011
synaptic vesicle localization GO:0097479 53 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
organic acid metabolic process GO:0006082 103 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
positive regulation of binding GO:0051099 4 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
digestive tract morphogenesis GO:0048546 127 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
autophagy GO:0006914 108 0.011
regulation of apoptotic process GO:0042981 130 0.011
neurological system process GO:0050877 358 0.011
mesoderm development GO:0007498 78 0.011
aging GO:0007568 143 0.011
oxoacid metabolic process GO:0043436 103 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
ameboidal type cell migration GO:0001667 151 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
cellular response to organic substance GO:0071310 132 0.010
determination of adult lifespan GO:0008340 137 0.010
regulation of timing of cell differentiation GO:0048505 1 0.010
stem cell proliferation GO:0072089 88 0.010
reproductive system development GO:0061458 74 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
death GO:0016265 284 0.010

l(2)gd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049