Drosophila melanogaster

161 known processes

Dcr-1 (Dmel_CG4792)

Dicer-1

(Aliases: dicer,dcr 1,Dicer1,Dmel\CG4792,DCR1,dcr1,dicer-1,CG4792,Dcr1,dicer1,Dicer,cg4792,DICER,dcr-1,Dcr)

Dcr-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived oocyte fate determination GO:0007294 26 0.973
oocyte fate determination GO:0030716 27 0.924
germarium derived oocyte differentiation GO:0030706 29 0.904
germ line cyst formation GO:0048134 44 0.883
cell fate determination GO:0001709 91 0.809
axonogenesis GO:0007409 290 0.769
axon development GO:0061564 297 0.685
dendrite morphogenesis GO:0048813 199 0.677
establishment of localization in cell GO:0051649 402 0.623
negative regulation of response to stimulus GO:0048585 258 0.614
negative regulation of signaling GO:0023057 219 0.578
endocytosis GO:0006897 310 0.574
negative regulation of rna biosynthetic process GO:1902679 240 0.548
Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.531
Mouse
regulation of protein metabolic process GO:0051246 256 0.453
Mouse
regulation of cell development GO:0060284 215 0.438
Mouse
female germ line cyst formation GO:0048135 42 0.427
transcription from rna polymerase ii promoter GO:0006366 368 0.377
Mouse
wing disc morphogenesis GO:0007472 344 0.362
negative regulation of gene expression GO:0010629 387 0.355
cellular response to organic substance GO:0071310 132 0.344
taxis GO:0042330 304 0.323
positive regulation of cellular protein metabolic process GO:0032270 118 0.321
cellular response to chemical stimulus GO:0070887 199 0.317
negative regulation of biosynthetic process GO:0009890 277 0.316
Mouse Fly
germarium derived female germ line cyst formation GO:0030727 42 0.298
dendrite development GO:0016358 204 0.298
negative regulation of signal transduction GO:0009968 206 0.296
intracellular signal transduction GO:0035556 300 0.296
post embryonic appendage morphogenesis GO:0035120 385 0.283
regulation of cellular response to stress GO:0080135 89 0.281
negative regulation of cellular metabolic process GO:0031324 382 0.274
Mouse Fly
neuron projection guidance GO:0097485 241 0.271
production of mirnas involved in gene silencing by mirna GO:0035196 10 0.269
regulation of localization GO:0032879 275 0.262
immune system process GO:0002376 347 0.247
Mouse Fly
synapse organization GO:0050808 196 0.237
axon guidance GO:0007411 233 0.227
chemotaxis GO:0006935 249 0.222
single organism biosynthetic process GO:0044711 206 0.222
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.222
Mouse Worm
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.210
Mouse Fly
circadian rhythm GO:0007623 105 0.203
production of small rna involved in gene silencing by rna GO:0070918 15 0.202
oocyte microtubule cytoskeleton organization GO:0016325 35 0.194
regulation of cell death GO:0010941 173 0.193
Mouse
regulation of multicellular organismal development GO:2000026 414 0.192
Mouse
small gtpase mediated signal transduction GO:0007264 88 0.189
regulation of response to stress GO:0080134 200 0.188
Fly
muscle organ development GO:0007517 127 0.184
positive regulation of molecular function GO:0044093 136 0.179
positive regulation of rna metabolic process GO:0051254 271 0.178
Mouse Worm
appendage morphogenesis GO:0035107 397 0.177
Mouse
phosphorylation GO:0016310 294 0.176
Mouse
regulation of anatomical structure size GO:0090066 163 0.174
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.172
germarium derived egg chamber formation GO:0007293 101 0.172
positive regulation of protein metabolic process GO:0051247 128 0.170
negative regulation of cell communication GO:0010648 223 0.168
negative regulation of wnt signaling pathway GO:0030178 28 0.165
negative regulation of transcription dna templated GO:0045892 237 0.161
Mouse Fly
appendage development GO:0048736 401 0.161
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.161
Mouse
regulation of cell morphogenesis GO:0022604 163 0.157
ribonucleoprotein complex biogenesis GO:0022613 31 0.155
cell division GO:0051301 248 0.150
organophosphate metabolic process GO:0019637 195 0.149
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.145
Mouse
positive regulation of developmental growth GO:0048639 62 0.143
response to organic substance GO:0010033 284 0.142
chromosome localization GO:0050000 20 0.141
ncrna processing GO:0034470 30 0.135
regulation of programmed cell death GO:0043067 152 0.133
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.132
gliogenesis GO:0042063 80 0.130
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.127
Mouse
cellular macromolecular complex assembly GO:0034622 153 0.124
homeostatic process GO:0042592 199 0.124
defense response to other organism GO:0098542 225 0.122
Mouse Fly
response to nitrogen compound GO:1901698 90 0.122
regulation of response to gamma radiation GO:2001228 4 0.122
sister chromatid segregation GO:0000819 92 0.121
regulation of developmental growth GO:0048638 174 0.120
response to biotic stimulus GO:0009607 294 0.120
Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.119
Mouse Fly
posttranscriptional gene silencing GO:0016441 46 0.116
gene silencing by mirna GO:0035195 22 0.115
regulation of wnt signaling pathway GO:0030111 68 0.114
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.112
regulation of neuron projection development GO:0010975 69 0.106
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.106
organic cyclic compound catabolic process GO:1901361 168 0.105
Worm Fly
regulation of cellular component biogenesis GO:0044087 201 0.103
cell proliferation GO:0008283 299 0.103
embryo development ending in birth or egg hatching GO:0009792 152 0.100
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.099
Mouse Fly
posttranscriptional gene silencing by rna GO:0035194 45 0.098
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.097
Mouse
developmental growth GO:0048589 280 0.094
Mouse
organ growth GO:0035265 56 0.094
regulation of cellular protein metabolic process GO:0032268 243 0.093
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.092
response to oxygen containing compound GO:1901700 200 0.091
ncrna metabolic process GO:0034660 43 0.090
organonitrogen compound metabolic process GO:1901564 318 0.089
Fly
positive regulation of response to stimulus GO:0048584 323 0.088
Worm
positive regulation of phosphate metabolic process GO:0045937 139 0.085
wnt signaling pathway GO:0016055 98 0.083
carbohydrate derivative metabolic process GO:1901135 217 0.082
Fly
organic substance catabolic process GO:1901575 308 0.082
Worm Fly
protein complex assembly GO:0006461 200 0.081
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.080
Mouse
outflow tract morphogenesis GO:0003151 4 0.078
Mouse
protein modification process GO:0036211 438 0.077
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.076
Mouse
response to organonitrogen compound GO:0010243 75 0.076
nucleobase containing compound catabolic process GO:0034655 165 0.076
Worm Fly
protein localization GO:0008104 284 0.075
regulation of mitotic cell cycle GO:0007346 190 0.075
positive regulation of growth GO:0045927 75 0.075
nucleoside phosphate catabolic process GO:1901292 110 0.074
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.074
Mouse
camera type eye morphogenesis GO:0048593 2 0.074
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.074
Fly
biological adhesion GO:0022610 138 0.072
positive regulation of wnt signaling pathway GO:0030177 25 0.071
positive regulation of protein modification process GO:0031401 58 0.069
blastoderm segmentation GO:0007350 159 0.065
positive regulation of chromosome segregation GO:0051984 10 0.065
regulation of mitosis GO:0007088 56 0.064
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.064
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.063
regulation of cell projection organization GO:0031344 92 0.062
protein modification by small protein conjugation GO:0032446 79 0.061
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.061
regulation of neural precursor cell proliferation GO:2000177 35 0.061
heterocycle catabolic process GO:0046700 166 0.060
Worm Fly
regulation of kinase activity GO:0043549 53 0.060
cellular response to nitrogen compound GO:1901699 51 0.059
cardiovascular system development GO:0072358 82 0.059
Mouse
regulation of cellular catabolic process GO:0031329 157 0.057
response to external biotic stimulus GO:0043207 293 0.056
Mouse Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.056
Fly
response to endogenous stimulus GO:0009719 119 0.056
stem cell differentiation GO:0048863 117 0.055
Mouse
tissue morphogenesis GO:0048729 297 0.055
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.054
imaginal disc derived leg morphogenesis GO:0007480 80 0.054
imaginal disc derived appendage development GO:0048737 399 0.054
positive regulation of biosynthetic process GO:0009891 316 0.053
Mouse
cellular macromolecule localization GO:0070727 220 0.052
positive regulation of transcription dna templated GO:0045893 266 0.052
Mouse
cell cycle phase transition GO:0044770 140 0.052
protein ubiquitination GO:0016567 70 0.052
mushroom body development GO:0016319 70 0.051
sex differentiation GO:0007548 81 0.050
Worm
protein modification by small protein conjugation or removal GO:0070647 106 0.050
mitotic sister chromatid segregation GO:0000070 87 0.049
lamellipodium assembly GO:0030032 21 0.049
response to wounding GO:0009611 94 0.048
Mouse
gene silencing by rna GO:0031047 57 0.047
cellular nitrogen compound catabolic process GO:0044270 165 0.047
Worm Fly
peptidyl amino acid modification GO:0018193 105 0.046
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.046
negative regulation of developmental process GO:0051093 201 0.045
Mouse
catabolic process GO:0009056 409 0.045
Worm Fly
regulation of intracellular signal transduction GO:1902531 236 0.045
retinal ganglion cell axon guidance GO:0031290 12 0.045
positive regulation of signal transduction GO:0009967 223 0.044
development of primary sexual characteristics GO:0045137 50 0.044
Worm
regulation of protein modification process GO:0031399 112 0.044
Mouse
leg disc morphogenesis GO:0007478 80 0.044
vesicle organization GO:0016050 44 0.044
positive regulation of phosphorylation GO:0042327 87 0.043
muscle structure development GO:0061061 224 0.043
Mouse
adherens junction assembly GO:0034333 11 0.043
regulation of transferase activity GO:0051338 58 0.042
regulation of protein kinase activity GO:0045859 51 0.042
sensory organ morphogenesis GO:0090596 260 0.042
endosomal transport GO:0016197 44 0.042
regulation of phosphorylation GO:0042325 147 0.041
Mouse
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.041
purine ribonucleoside catabolic process GO:0046130 112 0.041
Fly
regionalization GO:0003002 416 0.041
response to extracellular stimulus GO:0009991 116 0.040
circulatory system development GO:0072359 82 0.040
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
regulation of cellular localization GO:0060341 136 0.039
regulation of cell differentiation GO:0045595 302 0.038
Mouse
response to abiotic stimulus GO:0009628 341 0.037
cell projection assembly GO:0030031 94 0.037
positive regulation of cellular component organization GO:0051130 156 0.036
morphogenesis of an epithelium GO:0002009 276 0.036
Mouse
cell growth GO:0016049 108 0.036
dna methylation or demethylation GO:0044728 4 0.036
negative regulation of nervous system development GO:0051961 92 0.035
Mouse
cellular protein modification process GO:0006464 438 0.035
Mouse
regulation of gliogenesis GO:0014013 11 0.035
Mouse
regulation of epidermal cell differentiation GO:0045604 3 0.035
purine nucleotide metabolic process GO:0006163 146 0.035
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.034
regulation of canonical wnt signaling pathway GO:0060828 15 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.034
Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.034
regulation of molecular function GO:0065009 217 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.033
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 93 0.033
positive regulation of gliogenesis GO:0014015 5 0.033
Mouse
regulation of dendrite development GO:0050773 37 0.033
regulation of cell shape GO:0008360 113 0.032
eye morphogenesis GO:0048592 260 0.032
eye photoreceptor cell differentiation GO:0001754 145 0.032
purine nucleoside catabolic process GO:0006152 112 0.032
Fly
larval development GO:0002164 104 0.032
Worm
regulation of protein phosphorylation GO:0001932 64 0.032
Mouse
regulation of stem cell proliferation GO:0072091 40 0.032
nucleosome positioning GO:0016584 3 0.031
cellular lipid metabolic process GO:0044255 83 0.031
protein phosphorylation GO:0006468 169 0.031
Mouse
rhythmic process GO:0048511 106 0.031
camera type eye development GO:0043010 4 0.031
secretion GO:0046903 109 0.031
cell death GO:0008219 279 0.031
Mouse Worm
positive regulation of signaling GO:0023056 243 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
Mouse
establishment of rna localization GO:0051236 47 0.030
stem cell proliferation GO:0072089 88 0.030
reproductive system development GO:0061458 74 0.030
Mouse Worm
defense response to bacterium GO:0042742 178 0.030
ribonucleotide metabolic process GO:0009259 145 0.030
Fly
regulation of nucleotide metabolic process GO:0006140 62 0.030
wound healing GO:0042060 75 0.029
Mouse
heart development GO:0007507 82 0.029
Mouse
developmental maturation GO:0021700 172 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.029
organic substance transport GO:0071702 257 0.029
cellular response to dsrna GO:0071359 15 0.029
negative regulation of neurogenesis GO:0050768 53 0.028
Mouse
cellular amine metabolic process GO:0044106 12 0.028
cellular response to endogenous stimulus GO:0071495 80 0.028
purine nucleoside metabolic process GO:0042278 127 0.028
Fly
vesicle mediated transport GO:0016192 381 0.028
gene silencing GO:0016458 138 0.028
ubiquitin dependent protein catabolic process GO:0006511 78 0.028
regulation of growth GO:0040008 233 0.028
positive regulation of cell communication GO:0010647 250 0.027
positive regulation of cell cycle GO:0045787 43 0.027
ras protein signal transduction GO:0007265 88 0.026
single organism catabolic process GO:0044712 228 0.026
Fly
cuticle development GO:0042335 86 0.026
negative regulation of apoptotic process GO:0043066 63 0.026
multicellular organismal reproductive behavior GO:0033057 110 0.026
Worm
rna processing GO:0006396 147 0.026
negative regulation of developmental growth GO:0048640 64 0.025
regulation of system process GO:0044057 36 0.025
Mouse
purine nucleotide catabolic process GO:0006195 109 0.025
Fly
molting cycle chitin based cuticle GO:0007591 56 0.025
apoptotic process GO:0006915 159 0.025
Mouse Worm
hematopoietic or lymphoid organ development GO:0048534 57 0.024
Mouse
signal transduction by phosphorylation GO:0023014 107 0.024
regulation of cellular component size GO:0032535 98 0.024
positive regulation of cell cycle process GO:0090068 28 0.024
negative regulation of cell cycle phase transition GO:1901988 103 0.024
growth GO:0040007 359 0.024
Mouse
glial cell differentiation GO:0010001 35 0.023
Mouse
defense response GO:0006952 300 0.023
Mouse Worm Fly
ribonucleoprotein complex subunit organization GO:0071826 28 0.023
retina development in camera type eye GO:0060041 4 0.023
negative regulation of gene expression epigenetic GO:0045814 77 0.023
Fly
aromatic compound catabolic process GO:0019439 166 0.023
Worm Fly
positive regulation of rho gtpase activity GO:0032321 19 0.023
regulation of cell growth GO:0001558 43 0.023
regulation of cell size GO:0008361 63 0.022
modification dependent macromolecule catabolic process GO:0043632 79 0.022
regulation of catalytic activity GO:0050790 185 0.022
immune response GO:0006955 246 0.022
cellular catabolic process GO:0044248 372 0.022
Worm Fly
actin filament organization GO:0007015 126 0.022
response to other organism GO:0051707 293 0.022
Mouse Fly
multi multicellular organism process GO:0044706 123 0.022
Worm
regulation of cell cycle phase transition GO:1901987 130 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
positive regulation of nucleotide catabolic process GO:0030813 46 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
Fly
positive regulation of developmental process GO:0051094 143 0.021
Mouse
dna methylation GO:0006306 4 0.021
protein complex biogenesis GO:0070271 201 0.021
Mouse
regulation of protein stability GO:0031647 43 0.020
phagocytosis GO:0006909 215 0.020
regulation of ras protein signal transduction GO:0046578 93 0.020
macromolecule catabolic process GO:0009057 161 0.020
Worm
embryonic pattern specification GO:0009880 174 0.020
cystoblast division GO:0007282 10 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.020
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.019
nucleotide metabolic process GO:0009117 161 0.019
Fly
specification of symmetry GO:0009799 13 0.019
forebrain development GO:0030900 2 0.019
Mouse
positive regulation of cell development GO:0010720 61 0.019
Mouse
regulation of catabolic process GO:0009894 170 0.019
regulation of mitotic sister chromatid segregation GO:0033047 28 0.019
positive regulation of nervous system development GO:0051962 69 0.019
Mouse
chromosome separation GO:0051304 42 0.019
response to dsrna GO:0043331 15 0.019
regulation of cellular response to insulin stimulus GO:1900076 17 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
Mouse Fly
positive regulation of nucleotide metabolic process GO:0045981 55 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
gonad development GO:0008406 50 0.019
Worm
cell cycle g1 s phase transition GO:0044843 31 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.018
body morphogenesis GO:0010171 2 0.018
molting cycle GO:0042303 56 0.018
Mouse
connective tissue development GO:0061448 3 0.018
Mouse
multicellular organismal aging GO:0010259 140 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
positive regulation of protein phosphorylation GO:0001934 34 0.018
retina morphogenesis in camera type eye GO:0060042 2 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
Fly
neuroblast proliferation GO:0007405 74 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
respiratory system development GO:0060541 213 0.018
Mouse
tube development GO:0035295 244 0.017
Mouse
rna phosphodiester bond hydrolysis GO:0090501 17 0.017
oocyte development GO:0048599 124 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
purine containing compound metabolic process GO:0072521 155 0.017
Fly
positive regulation of transport GO:0051050 92 0.017
small molecule metabolic process GO:0044281 305 0.017
Fly
stem cell maintenance GO:0019827 67 0.017
Mouse
negative regulation of response to gamma radiation GO:2001229 4 0.017
canonical wnt signaling pathway GO:0060070 21 0.017
response to ionizing radiation GO:0010212 32 0.017
embryonic morphogenesis GO:0048598 206 0.017
Mouse
cellular macromolecule catabolic process GO:0044265 136 0.017
Worm
embryonic organ development GO:0048568 50 0.017
regulation of cell cycle g1 s phase transition GO:1902806 23 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
Fly
regulation of transport GO:0051049 181 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
actin cytoskeleton organization GO:0030036 206 0.016
regulation of dendrite morphogenesis GO:0048814 28 0.016
pole cell development GO:0007277 26 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
epidermal cell differentiation GO:0009913 51 0.016
neural precursor cell proliferation GO:0061351 75 0.016
negative regulation of programmed cell death GO:0043069 72 0.016
stem cell division GO:0017145 69 0.016
hindbrain development GO:0030902 2 0.016
proteasomal protein catabolic process GO:0010498 59 0.016
pharynx development GO:0060465 1 0.016
positive regulation of kinase activity GO:0033674 25 0.016
histone ubiquitination GO:0016574 4 0.016
cell aging GO:0007569 2 0.016
regulation of cell proliferation GO:0042127 163 0.016
Mouse
anterior posterior pattern specification GO:0009952 136 0.016
cellular response to peptide GO:1901653 28 0.015
single organism behavior GO:0044708 391 0.015
Worm
cellular response to organic cyclic compound GO:0071407 32 0.015
primary mirna processing GO:0031053 5 0.015
Worm
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
determination of bilateral symmetry GO:0009855 13 0.015
cell adhesion GO:0007155 136 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
Fly
regulation of translation GO:0006417 56 0.015
mitotic sister chromatid cohesion GO:0007064 6 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
anatomical structure homeostasis GO:0060249 97 0.015
pigmentation GO:0043473 75 0.015
negative regulation of cell death GO:0060548 81 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
negative regulation of dendrite morphogenesis GO:0050774 2 0.014
eye photoreceptor cell development GO:0042462 81 0.014
regulation of epithelial cell differentiation GO:0030856 4 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
Fly
positive regulation of cell death GO:0010942 69 0.014
asymmetric protein localization GO:0008105 33 0.014
protein catabolic process GO:0030163 101 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
cellular protein catabolic process GO:0044257 83 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
Mouse
positive regulation of ras gtpase activity GO:0032320 36 0.014
positive regulation of catabolic process GO:0009896 105 0.014
compound eye development GO:0048749 307 0.014
cell substrate adhesion GO:0031589 10 0.014
regulation of axonogenesis GO:0050770 32 0.014
regulation of nervous system development GO:0051960 248 0.014
Mouse
jak stat cascade GO:0007259 49 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.013
mitotic nuclear division GO:0007067 213 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.013
neuron remodeling GO:0016322 29 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
Fly
regulation of ras gtpase activity GO:0032318 38 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
Fly
regulation of neuroblast proliferation GO:1902692 34 0.013
macromolecular complex assembly GO:0065003 256 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
learning or memory GO:0007611 141 0.013
Worm
digestive tract development GO:0048565 149 0.013
Mouse
response to peptide GO:1901652 29 0.013
oocyte differentiation GO:0009994 145 0.013
chromosome organization GO:0051276 360 0.013
Fly
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.013
eye development GO:0001654 323 0.012
regulation of dna templated transcription elongation GO:0032784 17 0.012
regulation of apoptotic process GO:0042981 130 0.012
Mouse
larval midgut histolysis GO:0035069 22 0.012
positive regulation of gtp catabolic process GO:0033126 43 0.012
activation of jun kinase activity GO:0007257 3 0.012
regulation of neurogenesis GO:0050767 158 0.012
Mouse
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.012
positive regulation of organelle organization GO:0010638 65 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
Fly
dendrite guidance GO:0070983 21 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
stem cell development GO:0048864 79 0.012
Mouse
regulation of nucleoside metabolic process GO:0009118 50 0.012
limb morphogenesis GO:0035108 1 0.012
Mouse
negative regulation of cell proliferation GO:0008285 69 0.011
Mouse
g1 s transition of mitotic cell cycle GO:0000082 31 0.011
regulation of cell cycle process GO:0010564 181 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
Mouse Worm
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of organelle organization GO:0033043 196 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
regulation of cellular response to hypoxia GO:1900037 3 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
Fly
rna splicing GO:0008380 83 0.011
dna alkylation GO:0006305 4 0.011
establishment of epithelial cell apical basal polarity GO:0045198 10 0.011
regulation of mitotic sister chromatid separation GO:0010965 28 0.011
regulation of protein complex assembly GO:0043254 42 0.011
intracellular transport GO:0046907 228 0.011
protein transport GO:0015031 155 0.011
dsrna fragmentation GO:0031050 15 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
ribonucleoprotein complex assembly GO:0022618 23 0.010
oxoacid metabolic process GO:0043436 103 0.010
metaphase anaphase transition of cell cycle GO:0044784 28 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
mesoderm development GO:0007498 78 0.010
pole plasm mrna localization GO:0019094 49 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of protein serine threonine kinase activity GO:0071900 25 0.010
chaeta development GO:0022416 97 0.010
regulation of hydrolase activity GO:0051336 97 0.010
dna templated transcription elongation GO:0006354 18 0.010
neurological system process GO:0050877 358 0.010
Mouse Worm
regulation of hippo signaling GO:0035330 14 0.010
regulation of multi organism process GO:0043900 131 0.010
Mouse Fly

Dcr-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
Human
cancer DOID:162 0 0.013
Human