Drosophila melanogaster

165 known processes

ab (Dmel_CG4807)

abrupt

(Aliases: Ab,B2149,ptd,Dmel\CG4807,CG4807,clu,l(2)k02807)

ab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite morphogenesis GO:0048813 199 0.997
regulation of nervous system development GO:0051960 248 0.993
regulation of neurogenesis GO:0050767 158 0.991
dendrite development GO:0016358 204 0.986
axonogenesis GO:0007409 290 0.962
imaginal disc derived appendage morphogenesis GO:0035114 395 0.951
axon development GO:0061564 297 0.934
regulation of multicellular organismal development GO:2000026 414 0.925
appendage development GO:0048736 401 0.905
taxis GO:0042330 304 0.901
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.875
positive regulation of rna metabolic process GO:0051254 271 0.798
epithelial cell differentiation GO:0030855 322 0.782
chemotaxis GO:0006935 249 0.771
regulation of cell morphogenesis GO:0022604 163 0.765
regulation of cell differentiation GO:0045595 302 0.754
regulation of cell development GO:0060284 215 0.736
eye development GO:0001654 323 0.722
appendage morphogenesis GO:0035107 397 0.714
epithelial cell development GO:0002064 274 0.712
axon guidance GO:0007411 233 0.692
wing disc morphogenesis GO:0007472 344 0.684
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.664
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.622
positive regulation of transcription dna templated GO:0045893 266 0.608
positive regulation of nucleic acid templated transcription GO:1903508 266 0.596
negative regulation of cellular biosynthetic process GO:0031327 277 0.586
positive regulation of nervous system development GO:0051962 69 0.581
enzyme linked receptor protein signaling pathway GO:0007167 179 0.580
single organism intracellular transport GO:1902582 207 0.564
transcription from rna polymerase ii promoter GO:0006366 368 0.545
regulation of anatomical structure morphogenesis GO:0022603 242 0.543
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.540
establishment of localization in cell GO:0051649 402 0.539
neuron projection guidance GO:0097485 241 0.536
regionalization GO:0003002 416 0.536
regulation of dendrite morphogenesis GO:0048814 28 0.534
imaginal disc derived wing morphogenesis GO:0007476 337 0.531
negative regulation of developmental process GO:0051093 201 0.475
forebrain development GO:0030900 2 0.413
post embryonic appendage morphogenesis GO:0035120 385 0.412
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.411
eye antennal disc development GO:0035214 60 0.411
positive regulation of neurogenesis GO:0050769 41 0.399
negative regulation of cell differentiation GO:0045596 143 0.390
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.385
negative regulation of cell communication GO:0010648 223 0.384
eye morphogenesis GO:0048592 260 0.382
localization of cell GO:0051674 257 0.367
sensory organ morphogenesis GO:0090596 260 0.364
negative regulation of cell development GO:0010721 62 0.364
head development GO:0060322 135 0.354
positive regulation of rna biosynthetic process GO:1902680 266 0.347
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.340
regulation of localization GO:0032879 275 0.333
negative regulation of nervous system development GO:0051961 92 0.327
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.309
dendrite guidance GO:0070983 21 0.307
mushroom body development GO:0016319 70 0.304
cell cell signaling involved in cell fate commitment GO:0045168 210 0.302
brain development GO:0007420 120 0.298
negative regulation of signaling GO:0023057 219 0.295
positive regulation of cellular biosynthetic process GO:0031328 316 0.282
negative regulation of transcription dna templated GO:0045892 237 0.277
gtp catabolic process GO:0006184 72 0.258
ribonucleoside metabolic process GO:0009119 127 0.256
border follicle cell migration GO:0007298 113 0.244
oxoacid metabolic process GO:0043436 103 0.241
cell proliferation GO:0008283 299 0.240
negative regulation of signal transduction GO:0009968 206 0.233
negative regulation of cellular metabolic process GO:0031324 382 0.231
positive regulation of developmental process GO:0051094 143 0.226
positive regulation of cellular component organization GO:0051130 156 0.223
positive regulation of cell differentiation GO:0045597 64 0.222
negative regulation of response to stimulus GO:0048585 258 0.218
compound eye development GO:0048749 307 0.209
central nervous system development GO:0007417 201 0.208
negative regulation of gene expression GO:0010629 387 0.197
regulation of cell proliferation GO:0042127 163 0.196
negative regulation of biosynthetic process GO:0009890 277 0.196
regulation of neuron differentiation GO:0045664 103 0.195
regulation of growth GO:0040008 233 0.192
positive regulation of macromolecule metabolic process GO:0010604 405 0.190
epithelium migration GO:0090132 148 0.187
negative regulation of multicellular organismal process GO:0051241 142 0.185
small molecule metabolic process GO:0044281 305 0.185
positive regulation of gene expression GO:0010628 290 0.182
regulation of neuron projection development GO:0010975 69 0.179
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.172
neuroblast proliferation GO:0007405 74 0.170
positive regulation of cell development GO:0010720 61 0.147
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.146
tissue morphogenesis GO:0048729 297 0.146
cell migration GO:0016477 238 0.144
enteroendocrine cell differentiation GO:0035883 1 0.135
gliogenesis GO:0042063 80 0.135
molting cycle GO:0042303 56 0.128
immune system process GO:0002376 347 0.124
wnt signaling pathway GO:0016055 98 0.122
positive regulation of biosynthetic process GO:0009891 316 0.121
ovarian follicle cell development GO:0030707 248 0.115
neural precursor cell proliferation GO:0061351 75 0.109
stem cell division GO:0017145 69 0.108
tissue migration GO:0090130 155 0.108
heterocycle catabolic process GO:0046700 166 0.106
neuroblast division GO:0055057 35 0.104
columnar cuboidal epithelial cell development GO:0002066 249 0.100
regulation of imaginal disc derived wing size GO:0044719 20 0.099
stem cell maintenance GO:0019827 67 0.097
nucleoside metabolic process GO:0009116 127 0.096
developmental growth involved in morphogenesis GO:0060560 65 0.094
developmental maturation GO:0021700 172 0.092
telencephalon development GO:0021537 2 0.092
intracellular signal transduction GO:0035556 300 0.088
wing disc pattern formation GO:0035222 66 0.087
negative regulation of epithelial cell proliferation GO:0050680 4 0.086
positive regulation of axonogenesis GO:0050772 2 0.086
organonitrogen compound metabolic process GO:1901564 318 0.086
chaeta development GO:0022416 97 0.084
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.084
epithelial tube morphogenesis GO:0060562 88 0.083
vesicle mediated transport GO:0016192 381 0.083
regulation of dendrite development GO:0050773 37 0.082
eye photoreceptor cell differentiation GO:0001754 145 0.080
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.079
stem cell proliferation GO:0072089 88 0.079
glycosyl compound catabolic process GO:1901658 112 0.076
regulation of erbb signaling pathway GO:1901184 42 0.075
synapse assembly GO:0007416 143 0.074
spinal cord development GO:0021510 1 0.074
regulation of epithelial cell proliferation GO:0050678 4 0.069
negative regulation of cellular component organization GO:0051129 108 0.069
regulation of synapse organization GO:0050807 110 0.068
wing disc dorsal ventral pattern formation GO:0048190 47 0.068
negative regulation of neurogenesis GO:0050768 53 0.067
protein phosphorylation GO:0006468 169 0.066
lateral inhibition GO:0046331 206 0.066
guanosine containing compound catabolic process GO:1901069 74 0.065
regulation of cellular catabolic process GO:0031329 157 0.065
sex differentiation GO:0007548 81 0.064
camera type eye development GO:0043010 4 0.064
purine nucleotide catabolic process GO:0006195 109 0.060
purine ribonucleoside catabolic process GO:0046130 112 0.060
anterior posterior pattern specification GO:0009952 136 0.060
positive regulation of axon guidance GO:1902669 1 0.059
ribonucleoside catabolic process GO:0042454 112 0.059
salivary gland development GO:0007431 162 0.058
imaginal disc pattern formation GO:0007447 91 0.058
phagocytosis GO:0006909 215 0.056
gland development GO:0048732 191 0.055
instar larval development GO:0002168 55 0.055
positive regulation of neuron differentiation GO:0045666 26 0.054
negative regulation of cell death GO:0060548 81 0.054
negative regulation of growth GO:0045926 84 0.054
cellular response to organic substance GO:0071310 132 0.054
torso signaling pathway GO:0008293 21 0.054
photoreceptor cell axon guidance GO:0072499 23 0.054
cell death GO:0008219 279 0.054
camera type eye photoreceptor cell differentiation GO:0060219 2 0.053
protein localization GO:0008104 284 0.053
carbohydrate derivative catabolic process GO:1901136 118 0.053
negative regulation of wnt signaling pathway GO:0030178 28 0.052
stem cell differentiation GO:0048863 117 0.052
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.052
positive regulation of multicellular organismal process GO:0051240 143 0.052
epithelial cell migration GO:0010631 148 0.052
axis specification GO:0009798 167 0.051
cardiovascular system development GO:0072358 82 0.050
morphogenesis of an epithelium GO:0002009 276 0.049
muscle structure development GO:0061061 224 0.049
cellular amino acid metabolic process GO:0006520 61 0.049
purine containing compound catabolic process GO:0072523 112 0.048
imaginal disc derived appendage development GO:0048737 399 0.048
gtp metabolic process GO:0046039 72 0.047
purine nucleoside catabolic process GO:0006152 112 0.047
regulation of cellular amino acid metabolic process GO:0006521 0 0.045
intracellular transport GO:0046907 228 0.045
morphogenesis of a branching epithelium GO:0061138 45 0.044
regulation of glial cell differentiation GO:0045685 1 0.044
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.043
neuron remodeling GO:0016322 29 0.043
hematopoietic or lymphoid organ development GO:0048534 57 0.042
dorsal ventral pattern formation GO:0009953 133 0.042
regulation of molecular function GO:0065009 217 0.041
purine ribonucleotide catabolic process GO:0009154 109 0.041
regulation of catabolic process GO:0009894 170 0.041
regulation of protein modification process GO:0031399 112 0.041
neuron maturation GO:0042551 31 0.041
mesenchymal cell differentiation GO:0048762 1 0.040
antennal development GO:0007469 25 0.040
organic acid metabolic process GO:0006082 103 0.040
compound eye morphogenesis GO:0001745 249 0.039
actin filament based process GO:0030029 220 0.039
response to transforming growth factor beta GO:0071559 18 0.038
nucleoside catabolic process GO:0009164 112 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.038
regulation of anatomical structure size GO:0090066 163 0.037
regulation of synapse structure and activity GO:0050803 128 0.037
positive regulation of axon extension GO:0045773 2 0.037
cell fate commitment involved in pattern specification GO:0060581 31 0.036
nucleoside triphosphate catabolic process GO:0009143 108 0.035
photoreceptor cell differentiation GO:0046530 170 0.035
cell fate determination GO:0001709 91 0.035
bolwig s organ development GO:0055034 8 0.034
death GO:0016265 284 0.034
actin filament organization GO:0007015 126 0.034
actin filament bundle organization GO:0061572 28 0.034
regulation of cell size GO:0008361 63 0.033
purine nucleoside triphosphate catabolic process GO:0009146 108 0.033
organic substance transport GO:0071702 257 0.033
molting cycle chitin based cuticle GO:0007591 56 0.033
regulation of synapse assembly GO:0051963 94 0.033
catabolic process GO:0009056 409 0.033
protein ubiquitination GO:0016567 70 0.033
eye photoreceptor cell development GO:0042462 81 0.032
open tracheal system development GO:0007424 204 0.032
notum cell fate specification GO:0035310 5 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.031
cellular nitrogen compound catabolic process GO:0044270 165 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
regulation of cell death GO:0010941 173 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
regulation of cellular ketone metabolic process GO:0010565 3 0.030
regulation of axonogenesis GO:0050770 32 0.029
actin filament bundle assembly GO:0051017 26 0.029
nucleotide catabolic process GO:0009166 109 0.029
larval development GO:0002164 104 0.029
equator specification GO:0045317 4 0.029
branching morphogenesis of an epithelial tube GO:0048754 45 0.028
endocytosis GO:0006897 310 0.028
regulation of catalytic activity GO:0050790 185 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
embryonic hemopoiesis GO:0035162 26 0.028
developmental growth GO:0048589 280 0.028
programmed cell death GO:0012501 257 0.028
sensory perception of mechanical stimulus GO:0050954 72 0.028
protein transport GO:0015031 155 0.027
ribonucleotide catabolic process GO:0009261 109 0.027
formation of anatomical boundary GO:0048859 37 0.027
organic substance catabolic process GO:1901575 308 0.027
regulation of cellular amine metabolic process GO:0033238 3 0.027
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
stem cell development GO:0048864 79 0.027
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.027
kidney morphogenesis GO:0060993 3 0.027
cell fate specification involved in pattern specification GO:0060573 8 0.027
circulatory system development GO:0072359 82 0.026
leg disc development GO:0035218 92 0.026
cell maturation GO:0048469 144 0.026
terminal region determination GO:0007362 25 0.026
cellular response to chemical stimulus GO:0070887 199 0.026
cell fate specification GO:0001708 71 0.025
negative regulation of cell proliferation GO:0008285 69 0.025
r7 cell differentiation GO:0045466 43 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
response to organic substance GO:0010033 284 0.024
determination of dorsal ventral asymmetry GO:0048262 3 0.024
establishment of planar polarity GO:0001736 87 0.024
immune system development GO:0002520 57 0.024
positive regulation of cell communication GO:0010647 250 0.023
regulation of neural precursor cell proliferation GO:2000177 35 0.023
imaginal disc derived wing vein specification GO:0007474 48 0.023
retina development in camera type eye GO:0060041 4 0.023
regulation of stem cell proliferation GO:0072091 40 0.023
aromatic compound catabolic process GO:0019439 166 0.023
positive regulation of stem cell differentiation GO:2000738 3 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.022
cellular macromolecule localization GO:0070727 220 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
amine metabolic process GO:0009308 12 0.022
positive regulation of cell migration GO:0030335 2 0.022
limb morphogenesis GO:0035108 1 0.022
embryonic morphogenesis GO:0048598 206 0.022
ovarian follicle cell migration GO:0007297 121 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
purine nucleoside metabolic process GO:0042278 127 0.021
protein import GO:0017038 55 0.021
cellular response to organic cyclic compound GO:0071407 32 0.021
regulation of cell growth GO:0001558 43 0.021
response to abiotic stimulus GO:0009628 341 0.021
protein maturation GO:0051604 71 0.021
embryonic development via the syncytial blastoderm GO:0001700 148 0.021
regulation of wnt signaling pathway GO:0030111 68 0.021
retinal cone cell differentiation GO:0042670 2 0.021
substrate dependent cell migration GO:0006929 3 0.020
axon extension GO:0048675 32 0.020
morphogenesis of a branching structure GO:0001763 45 0.020
camera type eye morphogenesis GO:0048593 2 0.020
cellular catabolic process GO:0044248 372 0.020
neuron projection extension GO:1990138 32 0.020
regulation of protein deacetylation GO:0090311 2 0.019
cardiocyte differentiation GO:0035051 29 0.019
neural retina development GO:0003407 4 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
regulation of cellular component size GO:0032535 98 0.019
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.019
cellular ketone metabolic process GO:0042180 24 0.018
single organism nuclear import GO:1902593 51 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
positive regulation of protein deacetylation GO:0090312 2 0.018
response to alcohol GO:0097305 95 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
negative regulation of erbb signaling pathway GO:1901185 29 0.018
regulation of bmp signaling pathway GO:0030510 23 0.018
morphogenesis of embryonic epithelium GO:0016331 94 0.018
motor neuron axon guidance GO:0008045 58 0.018
response to sterol GO:0036314 34 0.018
respiratory system development GO:0060541 213 0.018
muscle organ development GO:0007517 127 0.018
reproductive structure development GO:0048608 74 0.017
exocrine system development GO:0035272 162 0.017
antennal morphogenesis GO:0048800 14 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
cellular protein modification process GO:0006464 438 0.017
nerve development GO:0021675 6 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
morphogenesis of follicular epithelium GO:0016333 36 0.017
positive regulation of developmental growth GO:0048639 62 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
regulation of cell projection organization GO:0031344 92 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
protein localization to organelle GO:0033365 82 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
chaeta morphogenesis GO:0008407 42 0.016
response to lipopolysaccharide GO:0032496 4 0.016
protein targeting GO:0006605 64 0.016
cell cell adhesion GO:0098609 26 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.015
response to growth factor GO:0070848 31 0.015
secretion by cell GO:0032940 101 0.015
protein complex assembly GO:0006461 200 0.015
larval somatic muscle development GO:0007526 19 0.015
single organism cell adhesion GO:0098602 47 0.015
muscle tissue development GO:0060537 30 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
embryonic organ development GO:0048568 50 0.015
jak stat cascade GO:0007259 49 0.015
organelle localization GO:0051640 148 0.015
nucleotide metabolic process GO:0009117 161 0.015
positive regulation of growth GO:0045927 75 0.015
bmp signaling pathway GO:0030509 27 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of neuroblast proliferation GO:0007406 27 0.014
apoptotic process GO:0006915 159 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
spinal cord patterning GO:0021511 1 0.014
positive regulation of protein modification process GO:0031401 58 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
cellular amine metabolic process GO:0044106 12 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
regulation of developmental growth GO:0048638 174 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
connective tissue development GO:0061448 3 0.014
imaginal disc derived leg segmentation GO:0036011 26 0.014
single organismal cell cell adhesion GO:0016337 45 0.014
cytoplasmic transport GO:0016482 130 0.014
regulation of axon extension GO:0030516 8 0.014
regulation of organelle organization GO:0033043 196 0.014
response to ecdysone GO:0035075 34 0.014
neuron recognition GO:0008038 101 0.014
positive regulation of catabolic process GO:0009896 105 0.013
cellular response to growth factor stimulus GO:0071363 30 0.013
growth GO:0040007 359 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
tube development GO:0035295 244 0.013
single organism cellular localization GO:1902580 180 0.013
male genitalia development GO:0030539 19 0.013
positive regulation of signal transduction GO:0009967 223 0.013
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.013
cell motility GO:0048870 251 0.013
limb development GO:0060173 1 0.013
establishment of protein localization GO:0045184 163 0.013
regulation of axon extension involved in axon guidance GO:0048841 4 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
regulation of cellular component movement GO:0051270 42 0.013
positive regulation of signaling GO:0023056 243 0.013
regulation of histone deacetylation GO:0031063 2 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.012
organ formation GO:0048645 39 0.012
positive regulation of gtp catabolic process GO:0033126 43 0.012
wing and notum subfield formation GO:0035309 13 0.012
cellular protein localization GO:0034613 160 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.012
negative regulation of molecular function GO:0044092 51 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
nuclear import GO:0051170 51 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
muscle attachment GO:0016203 36 0.012
regulation of cell motility GO:2000145 23 0.011
nitrogen compound transport GO:0071705 85 0.011
regulation of protein metabolic process GO:0051246 256 0.011
negative regulation of stem cell proliferation GO:2000647 30 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
maintenance of location GO:0051235 73 0.011
axon choice point recognition GO:0016198 26 0.011
eye antennal disc morphogenesis GO:0007455 34 0.011
retinal ganglion cell axon guidance GO:0031290 12 0.011
positive regulation of neuron projection development GO:0010976 14 0.011
regulation of programmed cell death GO:0043067 152 0.011
single organism catabolic process GO:0044712 228 0.011
phosphorylation GO:0016310 294 0.010
kidney development GO:0001822 3 0.010
regulation of organ formation GO:0003156 3 0.010
mesenchymal cell development GO:0014031 1 0.010
skeletal muscle fiber development GO:0048741 3 0.010
regulation of protein processing GO:0070613 32 0.010

ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.095
nervous system disease DOID:863 0 0.025
auditory system disease DOID:2742 0 0.024
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.024
nonsyndromic deafness DOID:0050563 0 0.024
sensory system disease DOID:0050155 0 0.024
disease of cellular proliferation DOID:14566 0 0.013