Drosophila melanogaster

14 known processes

Tequila (Dmel_CG4821)

CG4821 gene product from transcript CG4821-RE

(Aliases: CG18403,BEST:CK00198,CG4948,CG4821,Dmel\CG4821,SP72,anon-EST:ParkEST161,CG18153,teq,Teq,BEST:GH18038,CK00198,graal)

Tequila biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 358 0.653
response to abiotic stimulus GO:0009628 341 0.633
regulation of localization GO:0032879 275 0.450
organic acid metabolic process GO:0006082 103 0.390
carboxylic acid metabolic process GO:0019752 92 0.377
lipid localization GO:0010876 54 0.369
single organism behavior GO:0044708 391 0.369
response to oxygen containing compound GO:1901700 200 0.343
response to organic substance GO:0010033 284 0.338
response to peptide hormone GO:0043434 29 0.294
secretion GO:0046903 109 0.287
organonitrogen compound metabolic process GO:1901564 318 0.274
response to glucose GO:0009749 2 0.273
imaginal disc derived appendage development GO:0048737 399 0.232
oxoacid metabolic process GO:0043436 103 0.229
small molecule metabolic process GO:0044281 305 0.220
neutral lipid biosynthetic process GO:0046460 2 0.213
response to organonitrogen compound GO:0010243 75 0.203
negative regulation of gene expression GO:0010629 387 0.198
chemical homeostasis GO:0048878 92 0.193
response to monosaccharide GO:0034284 4 0.193
appendage morphogenesis GO:0035107 397 0.190
imaginal disc derived appendage morphogenesis GO:0035114 395 0.187
response to endogenous stimulus GO:0009719 119 0.183
cognition GO:0050890 141 0.179
single organism biosynthetic process GO:0044711 206 0.179
memory GO:0007613 94 0.166
regulation of heart rate GO:0002027 11 0.166
glycerolipid metabolic process GO:0046486 34 0.163
blood circulation GO:0008015 26 0.158
apoptotic process GO:0006915 159 0.158
regulation of hormone levels GO:0010817 40 0.157
developmental growth GO:0048589 280 0.156
response to hypoxia GO:0001666 53 0.156
response to insulin GO:0032868 29 0.155
negative regulation of cellular biosynthetic process GO:0031327 277 0.154
growth GO:0040007 359 0.154
cellular response to chemical stimulus GO:0070887 199 0.152
rhythmic process GO:0048511 106 0.149
negative regulation of cellular metabolic process GO:0031324 382 0.147
monocarboxylic acid metabolic process GO:0032787 29 0.147
post embryonic appendage morphogenesis GO:0035120 385 0.146
positive regulation of multicellular organismal process GO:0051240 143 0.144
cellular amide metabolic process GO:0043603 80 0.143
regulation of transport GO:0051049 181 0.137
positive regulation of biosynthetic process GO:0009891 316 0.135
positive regulation of sequestering of triglyceride GO:0010890 1 0.134
response to decreased oxygen levels GO:0036293 58 0.130
chemosensory behavior GO:0007635 106 0.122
response to organic cyclic compound GO:0014070 89 0.121
response to peptide GO:1901652 29 0.120
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.120
ion homeostasis GO:0050801 55 0.119
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.119
acylglycerol biosynthetic process GO:0046463 2 0.116
cellular response to oxygen containing compound GO:1901701 79 0.112
response to nitrogen compound GO:1901698 90 0.109
response to oxygen levels GO:0070482 59 0.109
response to hexose GO:0009746 3 0.107
response to lipid GO:0033993 38 0.106
regulation of multicellular organismal development GO:2000026 414 0.100
cellular ion homeostasis GO:0006873 39 0.100
homeostatic process GO:0042592 199 0.100
positive regulation of developmental process GO:0051094 143 0.099
cellular amine metabolic process GO:0044106 12 0.099
appendage development GO:0048736 401 0.098
olfactory behavior GO:0042048 97 0.095
response to metal ion GO:0010038 23 0.090
imaginal disc derived wing morphogenesis GO:0007476 337 0.090
ethanolamine containing compound metabolic process GO:0042439 4 0.088
cellular response to organic substance GO:0071310 132 0.086
circulatory system process GO:0003013 37 0.086
cholesterol transport GO:0030301 2 0.085
regulation of cell differentiation GO:0045595 302 0.081
signal release GO:0023061 49 0.080
monocarboxylic acid transport GO:0015718 3 0.080
positive regulation of gene expression GO:0010628 290 0.077
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.076
cellular modified amino acid metabolic process GO:0006575 45 0.076
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.075
maintenance of location GO:0051235 73 0.075
regulation of sequestering of triglyceride GO:0010889 3 0.073
response to alcohol GO:0097305 95 0.073
response to hormone GO:0009725 45 0.073
response to temperature stimulus GO:0009266 106 0.073
kidney development GO:0001822 3 0.073
organic substance catabolic process GO:1901575 308 0.072
long term memory GO:0007616 62 0.072
phosphatidylethanolamine metabolic process GO:0046337 1 0.072
protein modification process GO:0036211 438 0.072
regulation of cellular localization GO:0060341 136 0.070
regulation of blood circulation GO:1903522 21 0.069
triglyceride biosynthetic process GO:0019432 2 0.068
dna metabolic process GO:0006259 227 0.068
peptide metabolic process GO:0006518 80 0.067
cell death GO:0008219 279 0.067
organic substance transport GO:0071702 257 0.066
response to ethanol GO:0045471 59 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.065
wing disc morphogenesis GO:0007472 344 0.065
cellular chemical homeostasis GO:0055082 40 0.065
triglyceride catabolic process GO:0019433 3 0.065
positive regulation of lipid storage GO:0010884 4 0.064
heart process GO:0003015 37 0.063
death GO:0016265 284 0.063
cellular lipid metabolic process GO:0044255 83 0.062
circadian rhythm GO:0007623 105 0.062
endocytosis GO:0006897 310 0.061
rhythmic behavior GO:0007622 76 0.060
phosphatidic acid metabolic process GO:0046473 1 0.060
regionalization GO:0003002 416 0.058
lipid biosynthetic process GO:0008610 46 0.058
lipid metabolic process GO:0006629 121 0.057
cellular amino acid metabolic process GO:0006520 61 0.057
regulation of growth GO:0040008 233 0.056
cellular response to hexose stimulus GO:0071331 1 0.055
lipid catabolic process GO:0016042 21 0.054
anion homeostasis GO:0055081 3 0.054
response to carbohydrate GO:0009743 15 0.053
regulation of heart contraction GO:0008016 21 0.052
vesicle mediated transport GO:0016192 381 0.052
lipid storage GO:0019915 38 0.051
response to inorganic substance GO:0010035 44 0.050
circadian behavior GO:0048512 76 0.050
amine metabolic process GO:0009308 12 0.050
regulation of system process GO:0044057 36 0.050
sleep GO:0030431 49 0.050
regulation of programmed cell death GO:0043067 152 0.049
secretion by cell GO:0032940 101 0.049
fatty acid metabolic process GO:0006631 20 0.049
positive regulation of response to stimulus GO:0048584 323 0.048
regulation of lipid storage GO:0010883 22 0.048
oxidation reduction process GO:0055114 123 0.048
cellular catabolic process GO:0044248 372 0.048
response to bacterium GO:0009617 198 0.047
metal ion transport GO:0030001 74 0.047
cell migration GO:0016477 238 0.046
cell proliferation GO:0008283 299 0.045
cation homeostasis GO:0055080 51 0.044
response to external biotic stimulus GO:0043207 293 0.043
associative learning GO:0008306 65 0.042
cellular response to dna damage stimulus GO:0006974 223 0.042
cellular response to hormone stimulus GO:0032870 44 0.042
single organism catabolic process GO:0044712 228 0.041
cellular response to endogenous stimulus GO:0071495 80 0.041
response to biotic stimulus GO:0009607 294 0.041
cell cycle checkpoint GO:0000075 95 0.041
organic hydroxy compound biosynthetic process GO:1901617 21 0.041
lipid homeostasis GO:0055088 33 0.040
nuclear division GO:0000280 332 0.040
response to light stimulus GO:0009416 124 0.040
olfactory learning GO:0008355 56 0.040
sulfur compound metabolic process GO:0006790 59 0.039
positive regulation of cell migration GO:0030335 2 0.038
cellular homeostasis GO:0019725 80 0.038
response to transition metal nanoparticle GO:1990267 9 0.038
positive regulation of signaling GO:0023056 243 0.038
positive regulation of secretion GO:0051047 22 0.037
positive regulation of cell communication GO:0010647 250 0.036
negative regulation of rna metabolic process GO:0051253 251 0.036
positive regulation of cell motility GO:2000147 3 0.036
negative regulation of signaling GO:0023057 219 0.035
macromolecular complex assembly GO:0065003 256 0.035
cellular response to radiation GO:0071478 52 0.035
learning GO:0007612 75 0.035
triglyceride metabolic process GO:0006641 12 0.035
catabolic process GO:0009056 409 0.035
regulation of immune system process GO:0002682 176 0.033
regulation of secretion by cell GO:1903530 39 0.033
circadian sleep wake cycle process GO:0022410 24 0.033
cell motility GO:0048870 251 0.033
embryonic morphogenesis GO:0048598 206 0.033
negative regulation of biosynthetic process GO:0009890 277 0.033
single organism carbohydrate metabolic process GO:0044723 72 0.033
sulfur compound biosynthetic process GO:0044272 16 0.032
biological adhesion GO:0022610 138 0.032
negative regulation of rna biosynthetic process GO:1902679 240 0.032
positive regulation of transcription dna templated GO:0045893 266 0.031
enzyme linked receptor protein signaling pathway GO:0007167 179 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
circulatory system development GO:0072359 82 0.030
learning or memory GO:0007611 141 0.030
ion transport GO:0006811 145 0.030
negative regulation of cell differentiation GO:0045596 143 0.030
positive regulation of secretion by cell GO:1903532 20 0.030
synaptic transmission GO:0007268 288 0.030
protein complex biogenesis GO:0070271 201 0.029
regulation of cell death GO:0010941 173 0.029
regulation of secretion GO:0051046 44 0.029
sterol homeostasis GO:0055092 4 0.029
phagocytosis GO:0006909 215 0.029
small molecule biosynthetic process GO:0044283 37 0.029
dna damage checkpoint GO:0000077 78 0.028
negative regulation of cell communication GO:0010648 223 0.028
regulation of insulin secretion GO:0050796 5 0.028
regulation of protein transport GO:0051223 57 0.028
organophosphate metabolic process GO:0019637 195 0.027
regulation of establishment of protein localization GO:0070201 61 0.027
metal ion homeostasis GO:0055065 44 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
lipid transport GO:0006869 18 0.027
mitotic cell cycle checkpoint GO:0007093 88 0.026
positive regulation of behavior GO:0048520 19 0.026
alditol phosphate metabolic process GO:0052646 2 0.025
negative regulation of multicellular organismal process GO:0051241 142 0.025
regulation of apoptotic process GO:0042981 130 0.025
carbohydrate metabolic process GO:0005975 82 0.025
glutathione metabolic process GO:0006749 37 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
cellular metal ion homeostasis GO:0006875 31 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
regulation of protein metabolic process GO:0051246 256 0.024
spermatogenesis GO:0007283 200 0.024
cellular ketone metabolic process GO:0042180 24 0.024
spermatid differentiation GO:0048515 114 0.024
regulation of developmental growth GO:0048638 174 0.023
negative regulation of signal transduction GO:0009968 206 0.023
regulation of catabolic process GO:0009894 170 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
negative regulation of response to stimulus GO:0048585 258 0.023
proteolysis GO:0006508 192 0.023
cell growth GO:0016049 108 0.022
cardiovascular system development GO:0072358 82 0.022
cellular response to hypoxia GO:0071456 28 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
cellular cation homeostasis GO:0030003 38 0.022
cellular carbohydrate metabolic process GO:0044262 22 0.022
regulation of cell proliferation GO:0042127 163 0.022
response to organophosphorus GO:0046683 2 0.022
regulation of response to external stimulus GO:0032101 115 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of cell migration GO:0030334 22 0.022
regulation of peptide hormone secretion GO:0090276 5 0.022
positive regulation of rna metabolic process GO:0051254 271 0.021
regulation of peptide secretion GO:0002791 6 0.021
immune system process GO:0002376 347 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
cellular response to organonitrogen compound GO:0071417 36 0.021
lateral inhibition GO:0046331 206 0.021
circadian sleep wake cycle sleep GO:0050802 23 0.021
cellular response to nitrogen compound GO:1901699 51 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
cellular protein modification process GO:0006464 438 0.021
oxidoreduction coenzyme metabolic process GO:0006733 2 0.020
hormone metabolic process GO:0042445 33 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
locomotory behavior GO:0007626 176 0.020
cellular response to insulin stimulus GO:0032869 28 0.020
protein maturation GO:0051604 71 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
response to extracellular stimulus GO:0009991 116 0.020
regulation of behavior GO:0050795 75 0.019
regulation of cell development GO:0060284 215 0.019
response to drug GO:0042493 17 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
cellular divalent inorganic cation homeostasis GO:0072503 23 0.019
cholesterol homeostasis GO:0042632 3 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
negative regulation of developmental process GO:0051093 201 0.019
organonitrogen compound catabolic process GO:1901565 128 0.018
protein processing GO:0016485 68 0.018
regulation of catalytic activity GO:0050790 185 0.018
calcium ion homeostasis GO:0055074 23 0.018
male gamete generation GO:0048232 201 0.018
regulation of vesicle mediated transport GO:0060627 59 0.018
response to nutrient levels GO:0031667 114 0.018
regulation of sterol transport GO:0032371 1 0.018
regulation of nervous system development GO:0051960 248 0.018
regulation of response to wounding GO:1903034 19 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
meiotic cell cycle GO:0051321 171 0.018
mitotic dna integrity checkpoint GO:0044774 75 0.018
heart contraction GO:0060047 26 0.018
response to ecdysone GO:0035075 34 0.018
chemotaxis GO:0006935 249 0.017
positive regulation of signal transduction GO:0009967 223 0.017
internal protein amino acid acetylation GO:0006475 38 0.017
hormone catabolic process GO:0042447 3 0.017
cellular response to decreased oxygen levels GO:0036294 30 0.017
gland development GO:0048732 191 0.017
neurotransmitter catabolic process GO:0042135 1 0.017
dna integrity checkpoint GO:0031570 81 0.017
response to lipopolysaccharide GO:0032496 4 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
defense response to bacterium GO:0042742 178 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.017
regulation of reproductive process GO:2000241 54 0.017
tube development GO:0035295 244 0.017
establishment of localization in cell GO:0051649 402 0.017
regulation of transferase activity GO:0051338 58 0.017
glycoprotein metabolic process GO:0009100 41 0.016
negative regulation of cell death GO:0060548 81 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
alcohol metabolic process GO:0006066 25 0.016
feeding behavior GO:0007631 50 0.016
response to sterol GO:0036314 34 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
neutral lipid catabolic process GO:0046461 3 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
negative regulation of proteolysis GO:0045861 31 0.016
long chain fatty acid metabolic process GO:0001676 3 0.016
skeletal muscle fiber development GO:0048741 3 0.016
cellular response to external stimulus GO:0071496 66 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
pyridine nucleotide metabolic process GO:0019362 2 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
negative regulation of homeostatic process GO:0032845 2 0.015
localization of cell GO:0051674 257 0.015
cellular response to peptide GO:1901653 28 0.015
renal system development GO:0072001 72 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
regulation of locomotion GO:0040012 42 0.014
programmed cell death GO:0012501 257 0.014
urogenital system development GO:0001655 72 0.014
retina development in camera type eye GO:0060041 4 0.014
divalent inorganic cation homeostasis GO:0072507 29 0.014
cell division GO:0051301 248 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
developmental programmed cell death GO:0010623 138 0.014
mitotic g2 m transition checkpoint GO:0044818 70 0.014
protein phosphorylation GO:0006468 169 0.014
regulation of molecular function GO:0065009 217 0.014
antimicrobial humoral response GO:0019730 99 0.014
heart development GO:0007507 82 0.014
establishment of protein localization GO:0045184 163 0.013
regulation of lipid transport GO:0032368 3 0.013
neuron projection guidance GO:0097485 241 0.013
cellular response to monosaccharide stimulus GO:0071326 2 0.013
regulation of intracellular transport GO:0032386 64 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
regulation of proteolysis GO:0030162 87 0.013
regulation of intracellular protein transport GO:0033157 46 0.013
detection of chemical stimulus GO:0009593 93 0.013
steroid catabolic process GO:0006706 1 0.013
neutral lipid metabolic process GO:0006638 12 0.013
mitotic nuclear division GO:0007067 213 0.013
nadh metabolic process GO:0006734 1 0.013
response to wounding GO:0009611 94 0.013
carbohydrate biosynthetic process GO:0016051 17 0.013
antibacterial humoral response GO:0019731 44 0.013
negative regulation of protein processing GO:0010955 31 0.013
synapse organization GO:0050808 196 0.013
organic acid biosynthetic process GO:0016053 15 0.013
cellular response to peptide hormone stimulus GO:0071375 28 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
multicellular organism growth GO:0035264 46 0.013
regulation of neurogenesis GO:0050767 158 0.013
aging GO:0007568 143 0.013
nucleus organization GO:0006997 45 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
digestive tract development GO:0048565 149 0.012
glycerolipid catabolic process GO:0046503 3 0.012
negative regulation of growth GO:0045926 84 0.012
protein complex assembly GO:0006461 200 0.012
positive regulation of protein modification process GO:0031401 58 0.012
segmentation GO:0035282 207 0.012
regulation of response to stress GO:0080134 200 0.012
toxin metabolic process GO:0009404 2 0.012
regulation of cell division GO:0051302 72 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
acylglycerol metabolic process GO:0006639 12 0.012
response to calcium ion GO:0051592 1 0.012
positive regulation of transport GO:0051050 92 0.012
epithelial cell differentiation GO:0030855 322 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
nitrogen compound transport GO:0071705 85 0.012
regulation of protein processing GO:0070613 32 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
skeletal muscle organ development GO:0060538 48 0.011
cell adhesion GO:0007155 136 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
striated muscle tissue development GO:0014706 27 0.011
regulation of kinase activity GO:0043549 53 0.011
pigmentation GO:0043473 75 0.011
adult behavior GO:0030534 137 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
open tracheal system development GO:0007424 204 0.011
organelle localization GO:0051640 148 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
negative regulation of protein maturation GO:1903318 31 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of circadian rhythm GO:0042752 49 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
oligosaccharide transport GO:0015772 2 0.011
nicotinamide nucleotide metabolic process GO:0046496 2 0.011
organic anion transport GO:0015711 28 0.011
negative regulation of peptide hormone secretion GO:0090278 1 0.011
xenobiotic catabolic process GO:0042178 1 0.011
taxis GO:0042330 304 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
response to copper ion GO:0046688 4 0.010
organelle fission GO:0048285 340 0.010
axonogenesis GO:0007409 290 0.010
spermatid development GO:0007286 98 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
axon guidance GO:0007411 233 0.010
intracellular signal transduction GO:0035556 300 0.010
positive regulation of lipid metabolic process GO:0045834 4 0.010
regulation of cellular component movement GO:0051270 42 0.010
phosphatidylcholine metabolic process GO:0046470 3 0.010

Tequila disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.177
disease of metabolism DOID:0014667 0 0.084
familial hyperlipidemia DOID:1168 0 0.084
lipid metabolism disorder DOID:3146 0 0.084
inherited metabolic disorder DOID:655 0 0.084
familial combined hyperlipidemia DOID:13809 0 0.050
hair disease DOID:421 0 0.023
integumentary system disease DOID:16 0 0.023
nervous system disease DOID:863 0 0.021
cardiovascular system disease DOID:1287 0 0.020
familial lipoprotein lipase deficiency DOID:14118 0 0.020
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
diabetes mellitus DOID:9351 0 0.011
type 2 diabetes mellitus DOID:9352 0 0.011