Drosophila melanogaster

60 known processes

BicC (Dmel_CG4824)

Bicaudal C

(Aliases: Bic-C,Dmel\CG4824,CG4824,BG:DS00913.2,Dromel_CG4824_FBtr0080804_bicc_mORF,l(2)br34,br34)

BicC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell development GO:0030707 248 0.727
chorion containing eggshell formation GO:0007304 105 0.686
segmentation GO:0035282 207 0.439
anterior posterior pattern specification GO:0009952 136 0.422
embryonic pattern specification GO:0009880 174 0.406
negative regulation of gene expression GO:0010629 387 0.322
cellular component assembly involved in morphogenesis GO:0010927 151 0.316
blastoderm segmentation GO:0007350 159 0.312
fertilization GO:0009566 26 0.290
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.274
eggshell chorion assembly GO:0007306 66 0.272
regulation of oocyte development GO:0060281 27 0.241
oocyte anterior posterior axis specification GO:0007314 72 0.235
oocyte development GO:0048599 124 0.227
oocyte construction GO:0007308 112 0.212
eggshell formation GO:0030703 105 0.208
regulation of pole plasm oskar mrna localization GO:0007317 27 0.200
dorsal appendage formation GO:0046843 47 0.196
cellular macromolecule localization GO:0070727 220 0.187
germarium derived egg chamber formation GO:0007293 101 0.184
tripartite regional subdivision GO:0007351 103 0.180
embryonic axis specification GO:0000578 107 0.173
rna processing GO:0006396 147 0.168
regionalization GO:0003002 416 0.161
dna conformation change GO:0071103 105 0.154
Fly
axis specification GO:0009798 167 0.154
morphogenesis of follicular epithelium GO:0016333 36 0.153
purine ribonucleoside metabolic process GO:0046128 127 0.149
epithelial cell differentiation GO:0030855 322 0.142
germarium derived oocyte fate determination GO:0007294 26 0.140
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.137
single organism cellular localization GO:1902580 180 0.136
negative regulation of cellular metabolic process GO:0031324 382 0.136
egg coat formation GO:0035803 11 0.135
maternal determination of anterior posterior axis embryo GO:0008358 74 0.130
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.123
vitelline membrane formation GO:0030704 11 0.123
anterior posterior axis specification GO:0009948 109 0.121
columnar cuboidal epithelial cell development GO:0002066 249 0.120
nucleobase containing compound catabolic process GO:0034655 165 0.115
regulation of organelle organization GO:0033043 196 0.115
oocyte microtubule cytoskeleton organization GO:0016325 35 0.112
oocyte differentiation GO:0009994 145 0.111
pole plasm mrna localization GO:0019094 49 0.110
cell division GO:0051301 248 0.104
pole plasm oskar mrna localization GO:0045451 46 0.096
extracellular structure organization GO:0043062 46 0.096
gene silencing GO:0016458 138 0.091
chromatin organization GO:0006325 207 0.091
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.090
single fertilization GO:0007338 24 0.090
aromatic compound catabolic process GO:0019439 166 0.083
posttranscriptional gene silencing by rna GO:0035194 45 0.082
actin filament based process GO:0030029 220 0.082
cellular catabolic process GO:0044248 372 0.081
negative regulation of cell communication GO:0010648 223 0.081
Human
regulation of multicellular organismal development GO:2000026 414 0.078
single organism intracellular transport GO:1902582 207 0.078
oocyte axis specification GO:0007309 108 0.078
organelle fusion GO:0048284 46 0.077
regulation of cellular protein metabolic process GO:0032268 243 0.076
Fly
terminal region determination GO:0007362 25 0.076
anterior posterior axis specification embryo GO:0008595 103 0.075
vitelline membrane formation involved in chorion containing eggshell formation GO:0007305 11 0.075
mitotic nuclear division GO:0007067 213 0.072
regulation of mrna metabolic process GO:1903311 72 0.071
rna catabolic process GO:0006401 37 0.071
long term memory GO:0007616 62 0.070
intracellular mrna localization GO:0008298 66 0.070
epithelial cell development GO:0002064 274 0.068
establishment or maintenance of cell polarity GO:0007163 167 0.066
negative regulation of biosynthetic process GO:0009890 277 0.066
cell motility GO:0048870 251 0.064
carbohydrate derivative metabolic process GO:1901135 217 0.062
regulation of cellular localization GO:0060341 136 0.059
response to other organism GO:0051707 293 0.057
macromolecule catabolic process GO:0009057 161 0.057
establishment of localization in cell GO:0051649 402 0.057
death GO:0016265 284 0.055
positive regulation of rna metabolic process GO:0051254 271 0.055
gene silencing by rna GO:0031047 57 0.054
cellular macromolecule catabolic process GO:0044265 136 0.053
protein localization to organelle GO:0033365 82 0.053
programmed cell death GO:0012501 257 0.051
glycosyl compound metabolic process GO:1901657 127 0.050
oocyte dorsal ventral axis specification GO:0007310 34 0.050
phosphorylation GO:0016310 294 0.050
pole plasm rna localization GO:0007316 52 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.050
mrna processing GO:0006397 104 0.049
cellular nitrogen compound catabolic process GO:0044270 165 0.049
purine nucleoside triphosphate metabolic process GO:0009144 119 0.049
pole plasm assembly GO:0007315 61 0.048
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.048
vesicle mediated transport GO:0016192 381 0.047
periodic partitioning GO:0007365 29 0.047
chromosome organization GO:0051276 360 0.046
Fly
pole plasm protein localization GO:0007318 10 0.046
enzyme linked receptor protein signaling pathway GO:0007167 179 0.046
atp metabolic process GO:0046034 49 0.046
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.046
nucleus localization GO:0051647 34 0.045
phagocytosis GO:0006909 215 0.045
ameboidal type cell migration GO:0001667 151 0.045
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
heterocycle catabolic process GO:0046700 166 0.043
body morphogenesis GO:0010171 2 0.043
microtubule organizing center organization GO:0031023 168 0.043
negative regulation of rna metabolic process GO:0051253 251 0.042
neurological system process GO:0050877 358 0.042
rna localization GO:0006403 115 0.042
localization of cell GO:0051674 257 0.042
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.041
endocytosis GO:0006897 310 0.041
protein modification process GO:0036211 438 0.040
defense response to gram negative bacterium GO:0050829 94 0.040
mrna catabolic process GO:0006402 33 0.039
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.039
negative regulation of response to stimulus GO:0048585 258 0.039
Human
response to external biotic stimulus GO:0043207 293 0.039
regulation of translation GO:0006417 56 0.039
Fly
protein localization GO:0008104 284 0.038
regulation of meiosis GO:0040020 3 0.037
organic cyclic compound catabolic process GO:1901361 168 0.037
carbohydrate derivative biosynthetic process GO:1901137 85 0.036
posttranscriptional gene silencing GO:0016441 46 0.036
mitotic spindle organization GO:0007052 220 0.036
rna 3 end processing GO:0031123 45 0.036
cellular protein localization GO:0034613 160 0.036
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.035
centrosome organization GO:0051297 163 0.035
extracellular matrix assembly GO:0085029 13 0.035
chromosome condensation GO:0030261 41 0.034
Fly
regulation of gene expression epigenetic GO:0040029 128 0.034
cellular macromolecular complex assembly GO:0034622 153 0.034
developmental growth GO:0048589 280 0.033
regulation of cell division GO:0051302 72 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
positive regulation of transport GO:0051050 92 0.033
positive regulation of response to stimulus GO:0048584 323 0.032
organelle assembly GO:0070925 198 0.032
nucleotide metabolic process GO:0009117 161 0.032
negative regulation of rna biosynthetic process GO:1902679 240 0.031
torso signaling pathway GO:0008293 21 0.031
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.031
protein modification by small protein conjugation or removal GO:0070647 106 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.031
Fly
dna packaging GO:0006323 91 0.031
Fly
positive regulation of biosynthetic process GO:0009891 316 0.030
Fly
morphogenesis of an epithelium GO:0002009 276 0.030
appendage morphogenesis GO:0035107 397 0.030
synaptic transmission GO:0007268 288 0.029
nucleoside phosphate metabolic process GO:0006753 162 0.029
regulation of cell cycle GO:0051726 291 0.029
purine ribonucleotide metabolic process GO:0009150 145 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.029
tissue morphogenesis GO:0048729 297 0.029
cellular protein complex assembly GO:0043623 71 0.028
tube morphogenesis GO:0035239 191 0.028
response to bacterium GO:0009617 198 0.028
cytoplasmic translation GO:0002181 0 0.028
establishment of organelle localization GO:0051656 122 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
response to organonitrogen compound GO:0010243 75 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.027
cellular ketone metabolic process GO:0042180 24 0.027
pronuclear fusion GO:0007344 4 0.027
germarium derived oocyte differentiation GO:0030706 29 0.027
mrna 3 end processing GO:0031124 28 0.027
purine nucleotide metabolic process GO:0006163 146 0.026
response to oxygen containing compound GO:1901700 200 0.026
organic substance catabolic process GO:1901575 308 0.026
positive regulation of signaling GO:0023056 243 0.026
catabolic process GO:0009056 409 0.025
regulation of notch signaling pathway GO:0008593 100 0.025
response to nitrogen compound GO:1901698 90 0.024
dna replication GO:0006260 48 0.024
organic substance transport GO:0071702 257 0.024
actin filament organization GO:0007015 126 0.024
cognition GO:0050890 141 0.024
cell migration GO:0016477 238 0.024
nucleotide catabolic process GO:0009166 109 0.024
sex differentiation GO:0007548 81 0.024
regulation of mrna processing GO:0050684 71 0.023
maintenance of location in cell GO:0051651 28 0.023
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
wing disc morphogenesis GO:0007472 344 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
positive regulation of cell communication GO:0010647 250 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
cellular protein modification process GO:0006464 438 0.022
regulation of protein complex disassembly GO:0043244 29 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
adult behavior GO:0030534 137 0.021
spindle organization GO:0007051 253 0.021
negative regulation of signal transduction GO:0009968 206 0.021
Human
positive regulation of organelle organization GO:0010638 65 0.021
negative regulation of oskar mrna translation GO:0007319 5 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
regulation of catabolic process GO:0009894 170 0.020
organophosphate metabolic process GO:0019637 195 0.020
protein localization to nucleus GO:0034504 55 0.020
digestive tract morphogenesis GO:0048546 127 0.020
male gamete generation GO:0048232 201 0.020
notch signaling pathway GO:0007219 120 0.020
regulation of rna splicing GO:0043484 69 0.020
ribonucleotide metabolic process GO:0009259 145 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
spermatogenesis GO:0007283 200 0.020
intracellular signal transduction GO:0035556 300 0.020
response to abiotic stimulus GO:0009628 341 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
negative regulation of signaling GO:0023057 219 0.019
Human
germ cell migration GO:0008354 43 0.019
positive regulation of mrna catabolic process GO:0061014 5 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
developmental maturation GO:0021700 172 0.019
ribonucleoprotein complex subunit organization GO:0071826 28 0.019
intracellular transport GO:0046907 228 0.019
positive regulation of developmental process GO:0051094 143 0.019
regulation of growth GO:0040008 233 0.019
defense response to bacterium GO:0042742 178 0.019
response to temperature stimulus GO:0009266 106 0.019
regulation of mitosis GO:0007088 56 0.018
cell proliferation GO:0008283 299 0.018
oxoacid metabolic process GO:0043436 103 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
nucleoside monophosphate metabolic process GO:0009123 52 0.018
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.018
mrna metabolic process GO:0016071 124 0.018
muscle structure development GO:0061061 224 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
centrosome duplication GO:0051298 121 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
macromolecular complex disassembly GO:0032984 37 0.017
negative regulation of phosphate metabolic process GO:0045936 45 0.017
regulation of cell proliferation GO:0042127 163 0.017
regulation of protein metabolic process GO:0051246 256 0.017
Fly
purine nucleoside metabolic process GO:0042278 127 0.016
peptidyl threonine phosphorylation GO:0018107 2 0.016
regulation of transport GO:0051049 181 0.016
myofibril assembly GO:0030239 36 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
regulation of cell maturation GO:1903429 27 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
learning or memory GO:0007611 141 0.016
sodium dependent phosphate transport GO:0044341 2 0.015
response to drug GO:0042493 17 0.015
rna interference GO:0016246 27 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
single organism catabolic process GO:0044712 228 0.015
nucleoside metabolic process GO:0009116 127 0.015
histone modification GO:0016570 106 0.015
regulation of catalytic activity GO:0050790 185 0.015
digestive tract development GO:0048565 149 0.015
organelle fission GO:0048285 340 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
extracellular matrix organization GO:0030198 32 0.015
polarity specification of dorsal ventral axis GO:0009951 6 0.015
gland development GO:0048732 191 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
positive regulation of protein transport GO:0051222 37 0.015
establishment of protein localization GO:0045184 163 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
positive regulation of mrna metabolic process GO:1903313 5 0.014
purine containing compound metabolic process GO:0072521 155 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
organelle localization GO:0051640 148 0.014
regulation of nuclear division GO:0051783 58 0.014
chaeta morphogenesis GO:0008407 42 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
maintenance of protein location in cell GO:0032507 26 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
defense response to other organism GO:0098542 225 0.013
positive regulation of intracellular protein transport GO:0090316 30 0.013
appendage development GO:0048736 401 0.013
regulation of developmental growth GO:0048638 174 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
cell maturation GO:0048469 144 0.013
regulation of anatomical structure size GO:0090066 163 0.013
lysosomal transport GO:0007041 13 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
Fly
single organism biosynthetic process GO:0044711 206 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
cell fate determination GO:0001709 91 0.012
regulation of protein catabolic process GO:0042176 55 0.012
regulation of intracellular transport GO:0032386 64 0.012
positive regulation of multicellular organism growth GO:0040018 21 0.012
translation GO:0006412 69 0.012
Fly
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.012
negative regulation of developmental process GO:0051093 201 0.012
purine containing compound catabolic process GO:0072523 112 0.012
pigmentation GO:0043473 75 0.012
cell death GO:0008219 279 0.012
defense response to gram positive bacterium GO:0050830 41 0.012
organic acid metabolic process GO:0006082 103 0.012
eye morphogenesis GO:0048592 260 0.012
oocyte fate determination GO:0030716 27 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
cytoplasm organization GO:0007028 64 0.011
camera type eye development GO:0043010 4 0.011
regulation of protein import into nucleus GO:0042306 28 0.011
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.011
protein import GO:0017038 55 0.011
protein import into nucleus GO:0006606 51 0.011
regulation of sterol transport GO:0032371 1 0.011
learning GO:0007612 75 0.011
membrane organization GO:0061024 112 0.011
regulation of oskar mrna translation GO:0046011 8 0.011
multicellular organismal aging GO:0010259 140 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.011
peptidyl amino acid modification GO:0018193 105 0.011
regulation of cardioblast differentiation GO:0051890 9 0.011
nephron tubule development GO:0072080 3 0.011
stress activated mapk cascade GO:0051403 52 0.011
embryonic morphogenesis GO:0048598 206 0.011
response to hypoxia GO:0001666 53 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
chromatin remodeling GO:0006338 72 0.011
Fly
regulation of apoptotic process GO:0042981 130 0.011
single organism behavior GO:0044708 391 0.011
organonitrogen compound metabolic process GO:1901564 318 0.011
nucleoside catabolic process GO:0009164 112 0.011
regulation of nervous system development GO:0051960 248 0.011
developmental pigmentation GO:0048066 68 0.011
transmembrane transport GO:0055085 139 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
small molecule metabolic process GO:0044281 305 0.011
regulation of locomotion GO:0040012 42 0.011
amine metabolic process GO:0009308 12 0.011
oocyte maturation GO:0001556 3 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
cytoplasmic transport GO:0016482 130 0.010
nucleus organization GO:0006997 45 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of proteolysis GO:0030162 87 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
positive regulation of protein import into nucleus GO:0042307 21 0.010
purine nucleoside monophosphate catabolic process GO:0009128 38 0.010
stem cell differentiation GO:0048863 117 0.010
meiosis i GO:0007127 59 0.010

BicC disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
disease of anatomical entity DOID:7 0 0.024
cardiovascular system disease DOID:1287 0 0.024
organ system cancer DOID:0050686 0 0.019