Drosophila melanogaster

16 known processes

cbs (Dmel_CG4840)

centrosomin's beautiful sister

(Aliases: CG4840,dem,Dmel\CG4840)

cbs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellularization GO:0007349 90 0.908
centrosome cycle GO:0007098 137 0.869
gland morphogenesis GO:0022612 145 0.674
protein phosphorylation GO:0006468 169 0.464
phosphorylation GO:0016310 294 0.445
regulation of phosphate metabolic process GO:0019220 210 0.410
positive regulation of phosphate metabolic process GO:0045937 139 0.349
response to light stimulus GO:0009416 124 0.335
regulation of mapk cascade GO:0043408 92 0.323
regulation of phosphorylation GO:0042325 147 0.318
centrosome organization GO:0051297 163 0.261
negative regulation of developmental process GO:0051093 201 0.246
microtubule organizing center organization GO:0031023 168 0.240
determination of adult lifespan GO:0008340 137 0.239
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.227
regulation of phosphorus metabolic process GO:0051174 210 0.224
histolysis GO:0007559 102 0.217
signal transduction by phosphorylation GO:0023014 107 0.208
cellular protein modification process GO:0006464 438 0.206
positive regulation of response to stimulus GO:0048584 323 0.206
multicellular organismal aging GO:0010259 140 0.178
positive regulation of catalytic activity GO:0043085 118 0.169
negative regulation of cell cycle phase transition GO:1901988 103 0.160
mitotic spindle organization GO:0007052 220 0.155
positive regulation of phosphorylation GO:0042327 87 0.151
single organism behavior GO:0044708 391 0.149
negative regulation of cellular metabolic process GO:0031324 382 0.149
oocyte differentiation GO:0009994 145 0.147
mapk cascade GO:0000165 107 0.146
regulation of cellular protein metabolic process GO:0032268 243 0.142
death GO:0016265 284 0.137
cellular macromolecule localization GO:0070727 220 0.136
exocrine system development GO:0035272 162 0.134
protein modification process GO:0036211 438 0.133
regulation of multicellular organismal development GO:2000026 414 0.129
carbohydrate derivative metabolic process GO:1901135 217 0.126
nucleobase containing small molecule metabolic process GO:0055086 174 0.125
pole plasm rna localization GO:0007316 52 0.125
positive regulation of cellular protein metabolic process GO:0032270 118 0.121
positive regulation of phosphorus metabolic process GO:0010562 139 0.118
positive regulation of cellular biosynthetic process GO:0031328 316 0.118
ras protein signal transduction GO:0007265 88 0.113
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.112
regulation of catalytic activity GO:0050790 185 0.111
centrosome duplication GO:0051298 121 0.110
intracellular signal transduction GO:0035556 300 0.109
programmed cell death GO:0012501 257 0.109
aging GO:0007568 143 0.108
response to other organism GO:0051707 293 0.106
salivary gland morphogenesis GO:0007435 145 0.105
spindle organization GO:0007051 253 0.104
positive regulation of cell communication GO:0010647 250 0.103
organelle localization GO:0051640 148 0.103
positive regulation of macromolecule metabolic process GO:0010604 405 0.097
positive regulation of signaling GO:0023056 243 0.096
positive regulation of molecular function GO:0044093 136 0.090
catabolic process GO:0009056 409 0.090
salivary gland cell autophagic cell death GO:0035071 83 0.088
regulation of protein modification process GO:0031399 112 0.087
positive regulation of protein modification process GO:0031401 58 0.087
small molecule metabolic process GO:0044281 305 0.087
regulation of reproductive process GO:2000241 54 0.084
regulation of growth GO:0040008 233 0.077
negative regulation of developmental growth GO:0048640 64 0.075
salivary gland development GO:0007431 162 0.073
immune response GO:0006955 246 0.071
cellular nitrogen compound catabolic process GO:0044270 165 0.071
organic substance transport GO:0071702 257 0.070
positive regulation of signal transduction GO:0009967 223 0.068
regulation of intracellular signal transduction GO:1902531 236 0.068
developmental programmed cell death GO:0010623 138 0.068
organonitrogen compound metabolic process GO:1901564 318 0.067
tissue death GO:0016271 102 0.065
cellular protein localization GO:0034613 160 0.065
polysaccharide metabolic process GO:0005976 11 0.064
nucleotide metabolic process GO:0009117 161 0.064
purine ribonucleoside metabolic process GO:0046128 127 0.063
immune system process GO:0002376 347 0.063
cellular response to chemical stimulus GO:0070887 199 0.062
regulation of cellular catabolic process GO:0031329 157 0.061
cell death GO:0008219 279 0.060
regulation of small gtpase mediated signal transduction GO:0051056 93 0.060
regulation of protein kinase activity GO:0045859 51 0.060
aromatic compound catabolic process GO:0019439 166 0.059
regulation of molecular function GO:0065009 217 0.059
segmentation GO:0035282 207 0.059
regulation of protein metabolic process GO:0051246 256 0.057
regulation of transferase activity GO:0051338 58 0.057
positive regulation of intracellular signal transduction GO:1902533 116 0.057
salivary gland histolysis GO:0035070 88 0.056
stress activated mapk cascade GO:0051403 52 0.056
positive regulation of kinase activity GO:0033674 25 0.055
response to biotic stimulus GO:0009607 294 0.055
guanosine containing compound catabolic process GO:1901069 74 0.055
positive regulation of mapk cascade GO:0043410 63 0.054
nucleoside triphosphate catabolic process GO:0009143 108 0.054
regionalization GO:0003002 416 0.054
regulation of localization GO:0032879 275 0.052
protein localization to nucleus GO:0034504 55 0.052
localization of cell GO:0051674 257 0.052
response to abiotic stimulus GO:0009628 341 0.051
macromolecular complex assembly GO:0065003 256 0.051
protein localization GO:0008104 284 0.051
organic hydroxy compound metabolic process GO:1901615 83 0.050
carbohydrate derivative catabolic process GO:1901136 118 0.050
positive regulation of biosynthetic process GO:0009891 316 0.050
response to high light intensity GO:0009644 1 0.048
protein complex biogenesis GO:0070271 201 0.047
nitrogen compound transport GO:0071705 85 0.047
nuclear division GO:0000280 332 0.047
nucleoside triphosphate metabolic process GO:0009141 120 0.047
purine nucleotide metabolic process GO:0006163 146 0.046
cell motility GO:0048870 251 0.046
activation of protein kinase activity GO:0032147 12 0.045
regulation of protein phosphorylation GO:0001932 64 0.044
regulation of multi organism process GO:0043900 131 0.044
organic substance catabolic process GO:1901575 308 0.044
negative regulation of autophagy GO:0010507 16 0.044
negative regulation of cell differentiation GO:0045596 143 0.044
response to radiation GO:0009314 155 0.043
organonitrogen compound catabolic process GO:1901565 128 0.043
compound eye development GO:0048749 307 0.042
small gtpase mediated signal transduction GO:0007264 88 0.041
ribonucleoside metabolic process GO:0009119 127 0.040
positive regulation of transferase activity GO:0051347 26 0.040
embryonic development via the syncytial blastoderm GO:0001700 148 0.039
ribonucleoside triphosphate metabolic process GO:0009199 119 0.039
gtp metabolic process GO:0046039 72 0.039
intracellular mrna localization GO:0008298 66 0.039
vesicle mediated transport GO:0016192 381 0.039
spermatid development GO:0007286 98 0.037
establishment of protein localization GO:0045184 163 0.037
hemopoiesis GO:0030097 46 0.036
secondary metabolic process GO:0019748 75 0.036
purine nucleoside catabolic process GO:0006152 112 0.036
negative regulation of cellular biosynthetic process GO:0031327 277 0.035
organelle fission GO:0048285 340 0.035
stress activated protein kinase signaling cascade GO:0031098 55 0.035
spindle assembly involved in mitosis GO:0090307 50 0.034
response to organic substance GO:0010033 284 0.034
purine ribonucleotide metabolic process GO:0009150 145 0.033
growth GO:0040007 359 0.033
regulation of cell differentiation GO:0045595 302 0.033
nucleoside phosphate metabolic process GO:0006753 162 0.033
negative regulation of protein metabolic process GO:0051248 85 0.033
regulation of transport GO:0051049 181 0.033
purine nucleoside metabolic process GO:0042278 127 0.032
pole plasm assembly GO:0007315 61 0.032
pattern recognition receptor signaling pathway GO:0002221 2 0.032
regulation of kinase activity GO:0043549 53 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.032
regulation of antimicrobial peptide production GO:0002784 44 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
axis specification GO:0009798 167 0.032
protein transport GO:0015031 155 0.031
regulation of ras protein signal transduction GO:0046578 93 0.031
circadian sleep wake cycle process GO:0022410 24 0.031
ribose phosphate metabolic process GO:0019693 145 0.031
mitotic g2 dna damage checkpoint GO:0007095 69 0.030
protein localization to organelle GO:0033365 82 0.030
single organism cellular localization GO:1902580 180 0.029
mitotic dna integrity checkpoint GO:0044774 75 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.028
gland development GO:0048732 191 0.028
purine containing compound metabolic process GO:0072521 155 0.028
cell junction organization GO:0034330 57 0.028
heterocycle catabolic process GO:0046700 166 0.028
cellular catabolic process GO:0044248 372 0.028
regulation of behavior GO:0050795 75 0.027
muscle structure development GO:0061061 224 0.027
regulation of catabolic process GO:0009894 170 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
oocyte development GO:0048599 124 0.027
forebrain development GO:0030900 2 0.027
organonitrogen compound biosynthetic process GO:1901566 117 0.026
cell division GO:0051301 248 0.026
mitotic cell cycle checkpoint GO:0007093 88 0.026
rna transport GO:0050658 46 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
regulation of cell development GO:0060284 215 0.025
cellular response to light intensity GO:0071484 1 0.025
lateral inhibition GO:0046331 206 0.025
regulation of stress activated mapk cascade GO:0032872 41 0.025
nucleotide catabolic process GO:0009166 109 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
glycosyl compound catabolic process GO:1901658 112 0.025
pole plasm oskar mrna localization GO:0045451 46 0.025
jnk cascade GO:0007254 50 0.024
oocyte anterior posterior axis specification GO:0007314 72 0.024
regulation of hydrolase activity GO:0051336 97 0.024
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
cellular response to organic substance GO:0071310 132 0.024
positive regulation of gene expression GO:0010628 290 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
spindle assembly GO:0051225 80 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.024
developmental maturation GO:0021700 172 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
protein import into nucleus GO:0006606 51 0.023
nuclear import GO:0051170 51 0.023
feeding behavior GO:0007631 50 0.023
negative regulation of multicellular organismal process GO:0051241 142 0.023
regulation of cytoskeleton organization GO:0051493 89 0.023
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.023
single organism catabolic process GO:0044712 228 0.023
nucleoside phosphate catabolic process GO:1901292 110 0.022
dorsal closure GO:0007391 79 0.022
telencephalon development GO:0021537 2 0.022
purine containing compound catabolic process GO:0072523 112 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
regulation of nucleotide metabolic process GO:0006140 62 0.022
dendrite development GO:0016358 204 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
glycosaminoglycan catabolic process GO:0006027 3 0.022
cytoplasmic transport GO:0016482 130 0.022
interspecies interaction between organisms GO:0044419 16 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
response to external biotic stimulus GO:0043207 293 0.021
mitotic nuclear division GO:0007067 213 0.021
maintenance of location GO:0051235 73 0.021
mitotic cell cycle phase transition GO:0044772 138 0.021
purine nucleotide catabolic process GO:0006195 109 0.020
rna localization GO:0006403 115 0.020
macromolecule catabolic process GO:0009057 161 0.020
leg disc development GO:0035218 92 0.020
innate immune response activating signal transduction GO:0002758 2 0.020
regulation of immune system process GO:0002682 176 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.020
male gamete generation GO:0048232 201 0.020
oocyte construction GO:0007308 112 0.020
regulation of immune response GO:0050776 118 0.020
cellular amine metabolic process GO:0044106 12 0.020
organelle assembly GO:0070925 198 0.020
negative regulation of phosphorus metabolic process GO:0010563 45 0.020
pigment metabolic process GO:0042440 84 0.020
organophosphate metabolic process GO:0019637 195 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.019
immune response activating signal transduction GO:0002757 2 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
establishment of protein localization to organelle GO:0072594 62 0.019
establishment of organelle localization GO:0051656 122 0.019
regulation of jnk cascade GO:0046328 40 0.019
regulation of cell death GO:0010941 173 0.019
mitotic cell cycle embryonic GO:0045448 38 0.019
regulation of cell size GO:0008361 63 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
oocyte axis specification GO:0007309 108 0.019
guanosine containing compound metabolic process GO:1901068 74 0.019
centrosome localization GO:0051642 14 0.019
cell cycle arrest GO:0007050 4 0.018
negative regulation of gene expression GO:0010629 387 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
regulation of lipid metabolic process GO:0019216 15 0.018
positive regulation of protein phosphorylation GO:0001934 34 0.018
spermatid differentiation GO:0048515 114 0.018
organophosphate catabolic process GO:0046434 112 0.018
immune system development GO:0002520 57 0.018
defense response to other organism GO:0098542 225 0.018
gliogenesis GO:0042063 80 0.018
negative regulation of epithelial cell proliferation GO:0050680 4 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
positive regulation of catabolic process GO:0009896 105 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
response to bacterium GO:0009617 198 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
regulation of protein transport GO:0051223 57 0.017
regulation of response to nutrient levels GO:0032107 18 0.017
single organism biosynthetic process GO:0044711 206 0.017
wnt signaling pathway GO:0016055 98 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
regulation of circadian sleep wake cycle GO:0042749 25 0.017
regulation of programmed cell death GO:0043067 152 0.016
single organism intracellular transport GO:1902582 207 0.016
regulation of circadian rhythm GO:0042752 49 0.016
dna metabolic process GO:0006259 227 0.016
sodium ion transport GO:0006814 22 0.016
generation of precursor metabolites and energy GO:0006091 42 0.016
negative regulation of signal transduction GO:0009968 206 0.016
regulation of cellular component size GO:0032535 98 0.016
rho protein signal transduction GO:0007266 14 0.016
regulation of cellular amide metabolic process GO:0034248 39 0.016
glycogen metabolic process GO:0005977 6 0.016
regulation of defense response GO:0031347 102 0.016
defense response GO:0006952 300 0.015
regulation of neuron differentiation GO:0045664 103 0.015
compound eye morphogenesis GO:0001745 249 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
carbohydrate metabolic process GO:0005975 82 0.015
circadian behavior GO:0048512 76 0.015
detection of stimulus GO:0051606 156 0.015
response to virus GO:0009615 28 0.015
chromosome organization GO:0051276 360 0.015
phagocytosis GO:0006909 215 0.015
plasma membrane organization GO:0007009 26 0.015
regulation of response to external stimulus GO:0032101 115 0.015
negative regulation of growth GO:0045926 84 0.015
monocarboxylic acid transport GO:0015718 3 0.015
myotube cell development GO:0014904 3 0.014
positive regulation of immune response GO:0050778 63 0.014
regulation of cell division GO:0051302 72 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
mitotic g2 m transition checkpoint GO:0044818 70 0.014
positive regulation of organelle organization GO:0010638 65 0.014
cellular response to oxidative stress GO:0034599 28 0.014
succinate transport GO:0015744 2 0.014
antibacterial peptide biosynthetic process GO:0002780 22 0.014
dendrite morphogenesis GO:0048813 199 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
establishment of localization in cell GO:0051649 402 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
protein dna complex assembly GO:0065004 63 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.014
antibacterial humoral response GO:0019731 44 0.014
regulation of feeding behavior GO:0060259 16 0.014
regulation of production of molecular mediator of immune response GO:0002700 44 0.014
autophagic cell death GO:0048102 83 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
carbohydrate biosynthetic process GO:0016051 17 0.014
protein complex assembly GO:0006461 200 0.014
protein polymerization GO:0051258 42 0.014
cellular response to high light intensity GO:0071486 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
anterior posterior axis specification GO:0009948 109 0.014
phenol containing compound metabolic process GO:0018958 57 0.013
single organism nuclear import GO:1902593 51 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
regulation of cellular response to stress GO:0080135 89 0.013
cellular response to insulin stimulus GO:0032869 28 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
protein targeting to nucleus GO:0044744 51 0.013
regulation of organelle organization GO:0033043 196 0.013
regulation of embryonic development GO:0045995 68 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
germarium derived oocyte differentiation GO:0030706 29 0.013
muscle cell differentiation GO:0042692 103 0.013
glycosaminoglycan metabolic process GO:0030203 11 0.013
cellular homeostasis GO:0019725 80 0.013
negative regulation of cell cycle GO:0045786 116 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
aminoglycan catabolic process GO:0006026 6 0.013
dna integrity checkpoint GO:0031570 81 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
membrane organization GO:0061024 112 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
anterior posterior pattern specification GO:0009952 136 0.012
cell activation GO:0001775 9 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.012
cytoplasm organization GO:0007028 64 0.012
response to lipopolysaccharide GO:0032496 4 0.012
regulation of rho gtpase activity GO:0032319 20 0.012
cellular polysaccharide metabolic process GO:0044264 11 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
autophagy GO:0006914 108 0.012
nucleoside catabolic process GO:0009164 112 0.012
production of molecular mediator of immune response GO:0002440 46 0.012
negative regulation of cell communication GO:0010648 223 0.012
endocytosis GO:0006897 310 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
brain development GO:0007420 120 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.012
muscle organ development GO:0007517 127 0.012
ribonucleotide biosynthetic process GO:0009260 28 0.011
response to peptide GO:1901652 29 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
stem cell proliferation GO:0072089 88 0.011
regulation of mitosis GO:0007088 56 0.011
peptidyl amino acid modification GO:0018193 105 0.011
immune effector process GO:0002252 98 0.011
cellular carbohydrate biosynthetic process GO:0034637 7 0.011
cellular cation homeostasis GO:0030003 38 0.011
organic acid metabolic process GO:0006082 103 0.011
nucleoside metabolic process GO:0009116 127 0.011
energy derivation by oxidation of organic compounds GO:0015980 32 0.011
protein kinase b signaling GO:0043491 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
positive regulation of cell motility GO:2000147 3 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
peptidyl tyrosine phosphorylation GO:0018108 24 0.011
positive regulation of antimicrobial humoral response GO:0002760 28 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
nucleobase containing compound transport GO:0015931 56 0.011
carboxylic acid transport GO:0046942 18 0.011
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
germ cell migration GO:0008354 43 0.011
cellular response to lipid GO:0071396 20 0.011
embryonic axis specification GO:0000578 107 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
response to nitrogen compound GO:1901698 90 0.011
nucleus organization GO:0006997 45 0.010
hindbrain development GO:0030902 2 0.010
negative regulation of response to external stimulus GO:0032102 22 0.010
chemical homeostasis GO:0048878 92 0.010
striated muscle cell development GO:0055002 50 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of gtpase activity GO:0043087 44 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
establishment of rna localization GO:0051236 47 0.010
response to endogenous stimulus GO:0009719 119 0.010

cbs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031