Drosophila melanogaster

65 known processes

CG4857 (Dmel_CG4857)

CG4857 gene product from transcript CG4857-RD

(Aliases: EG:EG0007.4,Dmel\CG4857,EG:EG0007.12)

CG4857 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 0.989
circadian behavior GO:0048512 76 0.936
rhythmic process GO:0048511 106 0.894
regulation of circadian rhythm GO:0042752 49 0.749
negative regulation of gene expression GO:0010629 387 0.513
rhythmic behavior GO:0007622 76 0.499
locomotor rhythm GO:0045475 56 0.444
regulation of circadian sleep wake cycle GO:0042749 25 0.266
regulation of nervous system development GO:0051960 248 0.259
chromatin modification GO:0016568 147 0.223
chromatin organization GO:0006325 207 0.213
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.185
regulation of multicellular organismal development GO:2000026 414 0.177
cellular response to abiotic stimulus GO:0071214 58 0.170
locomotory behavior GO:0007626 176 0.146
organelle fission GO:0048285 340 0.137
chromatin assembly or disassembly GO:0006333 52 0.130
circadian sleep wake cycle GO:0042745 28 0.129
negative regulation of rna biosynthetic process GO:1902679 240 0.122
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.118
immune system process GO:0002376 347 0.118
circadian sleep wake cycle sleep GO:0050802 23 0.117
circadian sleep wake cycle process GO:0022410 24 0.116
entrainment of circadian clock GO:0009649 16 0.113
single organism behavior GO:0044708 391 0.105
negative regulation of nucleic acid templated transcription GO:1903507 240 0.104
positive regulation of rna biosynthetic process GO:1902680 266 0.101
male gamete generation GO:0048232 201 0.099
regulation of rna splicing GO:0043484 69 0.098
transcription from rna polymerase ii promoter GO:0006366 368 0.097
cellular macromolecule localization GO:0070727 220 0.097
protein modification process GO:0036211 438 0.097
regulation of catabolic process GO:0009894 170 0.095
regulation of behavior GO:0050795 75 0.093
compound eye morphogenesis GO:0001745 249 0.089
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.088
regulation of response to stress GO:0080134 200 0.085
regulation of cell differentiation GO:0045595 302 0.084
dna packaging GO:0006323 91 0.082
organic substance catabolic process GO:1901575 308 0.080
regulation of transport GO:0051049 181 0.079
spermatogenesis GO:0007283 200 0.078
covalent chromatin modification GO:0016569 106 0.077
macromolecular complex assembly GO:0065003 256 0.077
regulation of protein metabolic process GO:0051246 256 0.075
protein localization GO:0008104 284 0.074
eye development GO:0001654 323 0.073
cellular protein modification process GO:0006464 438 0.072
intracellular transport GO:0046907 228 0.072
negative regulation of rna metabolic process GO:0051253 251 0.070
regulation of photoreceptor cell differentiation GO:0046532 34 0.069
cellular response to radiation GO:0071478 52 0.067
positive regulation of gene expression GO:0010628 290 0.066
developmental growth GO:0048589 280 0.066
dna conformation change GO:0071103 105 0.066
columnar cuboidal epithelial cell development GO:0002066 249 0.066
regulation of neuron differentiation GO:0045664 103 0.065
cellular catabolic process GO:0044248 372 0.065
dna metabolic process GO:0006259 227 0.064
negative regulation of cellular metabolic process GO:0031324 382 0.061
signal release GO:0023061 49 0.061
nucleocytoplasmic transport GO:0006913 72 0.060
negative regulation of biosynthetic process GO:0009890 277 0.060
mrna metabolic process GO:0016071 124 0.058
macromolecule catabolic process GO:0009057 161 0.058
death GO:0016265 284 0.056
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.055
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.053
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.051
regulation of cell development GO:0060284 215 0.050
positive regulation of catabolic process GO:0009896 105 0.050
negative regulation of developmental process GO:0051093 201 0.050
cellular macromolecule catabolic process GO:0044265 136 0.049
nuclear division GO:0000280 332 0.048
chromosome organization GO:0051276 360 0.047
protein localization to nucleus GO:0034504 55 0.046
defense response GO:0006952 300 0.045
regulation of organelle organization GO:0033043 196 0.045
positive regulation of response to stimulus GO:0048584 323 0.045
negative regulation of cell communication GO:0010648 223 0.044
connective tissue development GO:0061448 3 0.044
compound eye development GO:0048749 307 0.043
negative regulation of signal transduction GO:0009968 206 0.043
regulation of mrna metabolic process GO:1903311 72 0.043
regulation of cellular localization GO:0060341 136 0.043
regulation of neurogenesis GO:0050767 158 0.043
regulation of mrna splicing via spliceosome GO:0048024 64 0.043
establishment of protein localization GO:0045184 163 0.043
regulation of molecular function GO:0065009 217 0.041
rna processing GO:0006396 147 0.040
single organism cellular localization GO:1902580 180 0.040
protein catabolic process GO:0030163 101 0.040
carbohydrate derivative metabolic process GO:1901135 217 0.040
protein complex biogenesis GO:0070271 201 0.040
gene silencing GO:0016458 138 0.040
cellular response to dna damage stimulus GO:0006974 223 0.040
carbohydrate derivative biosynthetic process GO:1901137 85 0.040
growth GO:0040007 359 0.039
organelle assembly GO:0070925 198 0.039
circadian regulation of gene expression GO:0032922 5 0.039
neurological system process GO:0050877 358 0.038
regulation of secretion by cell GO:1903530 39 0.038
small molecule metabolic process GO:0044281 305 0.038
catabolic process GO:0009056 409 0.038
dna integrity checkpoint GO:0031570 81 0.037
response to glucose GO:0009749 2 0.036
cellular macromolecular complex assembly GO:0034622 153 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.035
protein targeting GO:0006605 64 0.035
taxis GO:0042330 304 0.034
positive regulation of rna metabolic process GO:0051254 271 0.034
eye morphogenesis GO:0048592 260 0.034
ras protein signal transduction GO:0007265 88 0.034
cytoplasmic transport GO:0016482 130 0.034
sleep GO:0030431 49 0.034
anterior posterior pattern specification GO:0009952 136 0.034
response to radiation GO:0009314 155 0.033
rna splicing via transesterification reactions GO:0000375 73 0.032
innate immune response GO:0045087 144 0.032
epithelial cell development GO:0002064 274 0.032
single organism intracellular transport GO:1902582 207 0.031
cell death GO:0008219 279 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
determination of adult lifespan GO:0008340 137 0.030
regulation of cellular response to stress GO:0080135 89 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
purine nucleotide metabolic process GO:0006163 146 0.030
secretion GO:0046903 109 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
organonitrogen compound metabolic process GO:1901564 318 0.029
negative regulation of cellular biosynthetic process GO:0031327 277 0.029
cell cycle checkpoint GO:0000075 95 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.028
negative regulation of cellular protein metabolic process GO:0032269 85 0.028
developmental maturation GO:0021700 172 0.028
rna splicing GO:0008380 83 0.027
regulation of mrna processing GO:0050684 71 0.027
glial cell migration GO:0008347 31 0.027
meiotic cell cycle process GO:1903046 132 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
regulation of response to external stimulus GO:0032101 115 0.027
protein transport GO:0015031 155 0.027
response to nitrogen compound GO:1901698 90 0.027
negative regulation of response to stimulus GO:0048585 258 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
organic substance transport GO:0071702 257 0.026
cell proliferation GO:0008283 299 0.026
dna repair GO:0006281 54 0.026
compound eye photoreceptor cell differentiation GO:0001751 140 0.025
regulation of localization GO:0032879 275 0.025
oocyte axis specification GO:0007309 108 0.025
gene silencing by rna GO:0031047 57 0.025
rna localization GO:0006403 115 0.025
dendrite development GO:0016358 204 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.025
intracellular receptor signaling pathway GO:0030522 19 0.024
regulation of developmental growth GO:0048638 174 0.024
cellular amine metabolic process GO:0044106 12 0.024
aging GO:0007568 143 0.024
regulation of epithelial cell differentiation GO:0030856 4 0.024
segmentation GO:0035282 207 0.024
cellular response to light stimulus GO:0071482 37 0.024
modification dependent protein catabolic process GO:0019941 78 0.024
establishment of localization in cell GO:0051649 402 0.024
regionalization GO:0003002 416 0.024
positive regulation of biosynthetic process GO:0009891 316 0.023
lipid localization GO:0010876 54 0.023
histone modification GO:0016570 106 0.023
regulation of dendrite development GO:0050773 37 0.023
posttranscriptional gene silencing GO:0016441 46 0.023
learning or memory GO:0007611 141 0.022
positive regulation of proteolysis GO:0045862 52 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
protein targeting to nucleus GO:0044744 51 0.022
tissue morphogenesis GO:0048729 297 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
detection of stimulus GO:0051606 156 0.022
appendage morphogenesis GO:0035107 397 0.022
amine metabolic process GO:0009308 12 0.022
regulation of embryonic development GO:0045995 68 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
positive regulation of endopeptidase activity GO:0010950 26 0.021
multicellular organismal aging GO:0010259 140 0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.021
regulation of catalytic activity GO:0050790 185 0.021
purine containing compound metabolic process GO:0072521 155 0.021
glycoprotein metabolic process GO:0009100 41 0.021
alternative mrna splicing via spliceosome GO:0000380 60 0.021
negative regulation of signaling GO:0023057 219 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.021
purine containing compound biosynthetic process GO:0072522 30 0.021
mrna processing GO:0006397 104 0.020
regulation of cysteine type endopeptidase activity GO:2000116 27 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
single organism catabolic process GO:0044712 228 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
glycoprotein biosynthetic process GO:0009101 41 0.020
protein acetylation GO:0006473 39 0.020
immune response GO:0006955 246 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
heterocycle catabolic process GO:0046700 166 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.020
organic acid metabolic process GO:0006082 103 0.019
programmed cell death GO:0012501 257 0.019
peptidyl amino acid modification GO:0018193 105 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
reproductive behavior GO:0019098 122 0.019
skeletal muscle tissue development GO:0007519 13 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
sensory organ morphogenesis GO:0090596 260 0.019
regulation of cell cycle GO:0051726 291 0.019
cellular response to biotic stimulus GO:0071216 4 0.019
regulation of secretion GO:0051046 44 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
purine nucleoside monophosphate metabolic process GO:0009126 50 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
regulation of cell death GO:0010941 173 0.019
body morphogenesis GO:0010171 2 0.018
proteolysis GO:0006508 192 0.018
cell aging GO:0007569 2 0.018
axis specification GO:0009798 167 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
nucleoside phosphate biosynthetic process GO:1901293 34 0.018
oxoacid metabolic process GO:0043436 103 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
epidermal growth factor receptor signaling pathway GO:0007173 58 0.018
cell motility GO:0048870 251 0.018
protein import into nucleus GO:0006606 51 0.018
intracellular protein transport GO:0006886 104 0.018
positive regulation of signal transduction GO:0009967 223 0.018
regulation of ion transport GO:0043269 39 0.018
oocyte dorsal ventral axis specification GO:0007310 34 0.017
negative regulation of cell death GO:0060548 81 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
secretion by cell GO:0032940 101 0.017
long term memory GO:0007616 62 0.017
cellular protein localization GO:0034613 160 0.017
regulation of r7 cell differentiation GO:0045676 15 0.017
kidney development GO:0001822 3 0.017
intracellular signal transduction GO:0035556 300 0.017
detection of abiotic stimulus GO:0009582 66 0.017
heterochromatin organization GO:0070828 25 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
organophosphate metabolic process GO:0019637 195 0.017
nuclear import GO:0051170 51 0.017
atp metabolic process GO:0046034 49 0.017
mrna splicing via spliceosome GO:0000398 73 0.016
response to light stimulus GO:0009416 124 0.016
regulation of apoptotic process GO:0042981 130 0.016
regulation of protein localization GO:0032880 76 0.016
hormone secretion GO:0046879 7 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
protein complex assembly GO:0006461 200 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
cell division GO:0051301 248 0.016
cell maturation GO:0048469 144 0.016
sensory perception of chemical stimulus GO:0007606 116 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
actin filament based process GO:0030029 220 0.016
regulation of cell proliferation GO:0042127 163 0.015
mitotic nuclear division GO:0007067 213 0.015
apoptotic process GO:0006915 159 0.015
memory GO:0007613 94 0.015
vesicle mediated transport GO:0016192 381 0.015
single organism nuclear import GO:1902593 51 0.015
olfactory learning GO:0008355 56 0.015
protein import GO:0017038 55 0.015
compound eye photoreceptor development GO:0042051 78 0.015
imaginal disc pattern formation GO:0007447 91 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
response to temperature stimulus GO:0009266 106 0.015
negative regulation of neuron death GO:1901215 18 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
photoperiodism GO:0009648 10 0.014
positive regulation of peptidase activity GO:0010952 29 0.014
regulation of hydrolase activity GO:0051336 97 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
regulation of immune response GO:0050776 118 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.014
protein localization to organelle GO:0033365 82 0.014
response to abiotic stimulus GO:0009628 341 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
wound healing GO:0042060 75 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
positive regulation of immune system process GO:0002684 68 0.014
positive regulation of cell communication GO:0010647 250 0.014
nucleotide metabolic process GO:0009117 161 0.014
microtubule organizing center organization GO:0031023 168 0.014
imaginal disc derived appendage development GO:0048737 399 0.013
protein maturation GO:0051604 71 0.013
head development GO:0060322 135 0.013
wing disc dorsal ventral pattern formation GO:0048190 47 0.013
positive regulation of adenylate cyclase activity GO:0045762 8 0.013
protein acylation GO:0043543 42 0.013
response to other organism GO:0051707 293 0.013
negative regulation of gene expression epigenetic GO:0045814 77 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
chaeta development GO:0022416 97 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
regulation of programmed cell death GO:0043067 152 0.013
carbohydrate metabolic process GO:0005975 82 0.013
regulation of camp biosynthetic process GO:0030817 12 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
response to biotic stimulus GO:0009607 294 0.013
positive regulation of growth GO:0045927 75 0.013
glycerolipid catabolic process GO:0046503 3 0.013
nitrogen compound transport GO:0071705 85 0.013
regulation of protein catabolic process GO:0042176 55 0.013
actin cytoskeleton organization GO:0030036 206 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
organophosphate catabolic process GO:0046434 112 0.013
negative regulation of insulin secretion GO:0046676 1 0.013
ncrna metabolic process GO:0034660 43 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
tube development GO:0035295 244 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
phosphatidylinositol mediated signaling GO:0048015 4 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
multicellular organism growth GO:0035264 46 0.012
response to bacterium GO:0009617 198 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of transmembrane transport GO:0034762 27 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.012
mrna catabolic process GO:0006402 33 0.012
muscle structure development GO:0061061 224 0.012
photoreceptor cell development GO:0042461 96 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.012
positive regulation of defense response GO:0031349 59 0.012
single organism biosynthetic process GO:0044711 206 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
posttranscriptional gene silencing by rna GO:0035194 45 0.012
chromosome segregation GO:0007059 157 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of transcription regulatory region dna binding GO:2000677 3 0.012
phototransduction GO:0007602 52 0.012
negative regulation of phosphorus metabolic process GO:0010563 45 0.012
rhabdomere development GO:0042052 38 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
response to nutrient levels GO:0031667 114 0.011
negative regulation of cell development GO:0010721 62 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of immune system process GO:0002682 176 0.011
oocyte construction GO:0007308 112 0.011
ommatidial rotation GO:0016318 20 0.011
negative regulation of transposition GO:0010529 12 0.011
macromolecule methylation GO:0043414 45 0.011
regulation of cell cycle process GO:0010564 181 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
nucleoside metabolic process GO:0009116 127 0.011
larval development GO:0002164 104 0.011
rna interference GO:0016246 27 0.011
axon guidance GO:0007411 233 0.011
amide transport GO:0042886 10 0.011
lateral inhibition GO:0046331 206 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
adult locomotory behavior GO:0008344 76 0.011
stem cell proliferation GO:0072089 88 0.011
positive regulation of protein catabolic process GO:0045732 34 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
imaginal disc growth GO:0007446 37 0.011
phosphorylation GO:0016310 294 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
cellular protein complex assembly GO:0043623 71 0.011
translation GO:0006412 69 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
positive regulation of signaling GO:0023056 243 0.011
camp biosynthetic process GO:0006171 17 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.010
jnk cascade GO:0007254 50 0.010
gland morphogenesis GO:0022612 145 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
spermatid differentiation GO:0048515 114 0.010
response to organic substance GO:0010033 284 0.010
regulation of endopeptidase activity GO:0052548 36 0.010
defense response to bacterium GO:0042742 178 0.010
peptidyl lysine modification GO:0018205 57 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
response to oxygen containing compound GO:1901700 200 0.010
response to organophosphorus GO:0046683 2 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.010
regulation of cellular component size GO:0032535 98 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
positive regulation of developmental process GO:0051094 143 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010

CG4857 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
disease of metabolism DOID:0014667 0 0.013
eye disease DOID:5614 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011