Drosophila melanogaster

123 known processes

RecQ5 (Dmel_CG4879)

homolog of RecQ

(Aliases: Q1,Dm RECQ5/QE,dmRecQ5b,DmRECQ5,DQ1,anon-EST:Posey293,CG4879,RECQ5,RECQ5/QE,Dmel\CG4879,RECQE,Dq1)

RecQ5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna recombination GO:0006310 32 0.957
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.944
dna repair GO:0006281 54 0.937
dna metabolic process GO:0006259 227 0.935
reciprocal meiotic recombination GO:0007131 19 0.920
recombinational repair GO:0000725 13 0.918
double strand break repair via homologous recombination GO:0000724 13 0.864
dna geometric change GO:0032392 16 0.821
double strand break repair GO:0006302 26 0.743
meiotic cell cycle GO:0051321 171 0.707
cellular response to dna damage stimulus GO:0006974 223 0.694
dna duplex unwinding GO:0032508 16 0.689
dna synthesis involved in dna repair GO:0000731 5 0.652
dna double strand break processing GO:0000729 3 0.648
meiotic cell cycle process GO:1903046 132 0.638
translesion synthesis GO:0019985 2 0.555
female meiosis chromosome segregation GO:0016321 33 0.517
meiotic chromosome segregation GO:0045132 59 0.509
regulation of dna recombination GO:0000018 4 0.503
nuclear division GO:0000280 332 0.498
female meiotic division GO:0007143 70 0.489
developmental growth GO:0048589 280 0.472
growth GO:0040007 359 0.459
postreplication repair GO:0006301 2 0.415
mitotic g2 dna damage checkpoint GO:0007095 69 0.405
negative regulation of cell cycle phase transition GO:1901988 103 0.347
meiosis i GO:0007127 59 0.324
nucleotide excision repair GO:0006289 8 0.320
double strand break repair via nonhomologous end joining GO:0006303 5 0.309
dna damage checkpoint GO:0000077 78 0.297
dna conformation change GO:0071103 105 0.293
mitotic dna damage checkpoint GO:0044773 74 0.292
cellular response to abiotic stimulus GO:0071214 58 0.291
response to light stimulus GO:0009416 124 0.291
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.259
Human
mitotic cell cycle phase transition GO:0044772 138 0.259
mitotic dna integrity checkpoint GO:0044774 75 0.257
regulation of developmental growth GO:0048638 174 0.234
g2 dna damage checkpoint GO:0031572 69 0.233
cell division GO:0051301 248 0.230
non recombinational repair GO:0000726 7 0.220
male gamete generation GO:0048232 201 0.219
nucleotide metabolic process GO:0009117 161 0.217
negative regulation of rna biosynthetic process GO:1902679 240 0.211
Human
chromosome organization GO:0051276 360 0.172
chromosome separation GO:0051304 42 0.171
Human
response to abiotic stimulus GO:0009628 341 0.165
meiotic nuclear division GO:0007126 151 0.163
reciprocal dna recombination GO:0035825 19 0.159
telomere maintenance via recombination GO:0000722 1 0.152
ribonucleoside triphosphate catabolic process GO:0009203 108 0.152
mitotic g2 m transition checkpoint GO:0044818 70 0.151
regulation of cell cycle GO:0051726 291 0.135
regulation of cell cycle process GO:0010564 181 0.135
response to alkaloid GO:0043279 26 0.134
atp metabolic process GO:0046034 49 0.133
negative regulation of cell cycle process GO:0010948 109 0.132
multicellular organism growth GO:0035264 46 0.131
chromatin organization GO:0006325 207 0.125
gene silencing GO:0016458 138 0.123
aging GO:0007568 143 0.123
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.119
negative regulation of mitotic cell cycle GO:0045930 109 0.115
ribonucleoside monophosphate metabolic process GO:0009161 51 0.114
regulation of cell death GO:0010941 173 0.111
purine nucleotide metabolic process GO:0006163 146 0.109
intracellular signal transduction GO:0035556 300 0.108
organelle fission GO:0048285 340 0.108
nucleobase containing compound catabolic process GO:0034655 165 0.101
vesicle mediated transport GO:0016192 381 0.100
regulation of nuclear division GO:0051783 58 0.100
negative regulation of developmental process GO:0051093 201 0.097
negative regulation of developmental growth GO:0048640 64 0.093
ribonucleoside metabolic process GO:0009119 127 0.091
regulation of intracellular signal transduction GO:1902531 236 0.090
cellular response to radiation GO:0071478 52 0.089
chromatin modification GO:0016568 147 0.087
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.083
Human
eye morphogenesis GO:0048592 260 0.082
nucleoside monophosphate metabolic process GO:0009123 52 0.080
chromosome segregation GO:0007059 157 0.080
regulation of cell cycle phase transition GO:1901987 130 0.080
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.079
death GO:0016265 284 0.078
atp catabolic process GO:0006200 38 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.076
nucleoside triphosphate catabolic process GO:0009143 108 0.074
regulation of dna metabolic process GO:0051052 34 0.072
mitotic cell cycle checkpoint GO:0007093 88 0.072
regulation of meiosis GO:0040020 3 0.072
ribonucleoside triphosphate metabolic process GO:0009199 119 0.071
negative regulation of cell cycle GO:0045786 116 0.071
homeostatic process GO:0042592 199 0.069
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.068
organonitrogen compound metabolic process GO:1901564 318 0.067
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.067
Human
endocytosis GO:0006897 310 0.067
single organism catabolic process GO:0044712 228 0.066
compound eye development GO:0048749 307 0.065
cell proliferation GO:0008283 299 0.064
organic substance catabolic process GO:1901575 308 0.064
rna splicing GO:0008380 83 0.062
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.062
dna biosynthetic process GO:0071897 24 0.061
positive regulation of developmental process GO:0051094 143 0.060
regulation of mitotic cell cycle phase transition GO:1901990 130 0.059
negative regulation of growth GO:0045926 84 0.059
regulation of cellular response to stress GO:0080135 89 0.058
nucleotide catabolic process GO:0009166 109 0.057
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.057
Human
apoptotic process GO:0006915 159 0.057
organonitrogen compound catabolic process GO:1901565 128 0.055
response to oxidative stress GO:0006979 86 0.054
heterocycle catabolic process GO:0046700 166 0.054
purine ribonucleoside metabolic process GO:0046128 127 0.053
response to uv GO:0009411 24 0.053
regulation of organelle organization GO:0033043 196 0.053
purine ribonucleoside catabolic process GO:0046130 112 0.053
sex differentiation GO:0007548 81 0.053
mitotic sister chromatid segregation GO:0000070 87 0.052
eye development GO:0001654 323 0.050
regulation of multicellular organism growth GO:0040014 40 0.050
response to purine containing compound GO:0014074 12 0.050
cellular catabolic process GO:0044248 372 0.049
cell death GO:0008219 279 0.049
signal transduction in response to dna damage GO:0042770 3 0.049
purine ribonucleotide metabolic process GO:0009150 145 0.047
dna replication GO:0006260 48 0.046
Human
cellular response to ionizing radiation GO:0071479 15 0.046
ribose phosphate metabolic process GO:0019693 145 0.045
response to organic substance GO:0010033 284 0.044
negative regulation of rna metabolic process GO:0051253 251 0.044
Human
cellular response to gamma radiation GO:0071480 10 0.044
regulation of hydrolase activity GO:0051336 97 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
ribonucleoside monophosphate catabolic process GO:0009158 39 0.044
carbohydrate derivative catabolic process GO:1901136 118 0.042
regulation of double strand break repair GO:2000779 3 0.042
telomere capping GO:0016233 11 0.041
larval development GO:0002164 104 0.041
sensory organ morphogenesis GO:0090596 260 0.040
embryo development ending in birth or egg hatching GO:0009792 152 0.040
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.040
positive regulation of hydrolase activity GO:0051345 78 0.040
multicellular organismal aging GO:0010259 140 0.040
Worm
response to organic cyclic compound GO:0014070 89 0.040
ribonucleoside catabolic process GO:0042454 112 0.040
negative regulation of cellular metabolic process GO:0031324 382 0.040
Human
spermatogenesis GO:0007283 200 0.039
cellular response to chemical stimulus GO:0070887 199 0.039
nucleobase containing small molecule metabolic process GO:0055086 174 0.039
appendage morphogenesis GO:0035107 397 0.039
dna dependent dna replication GO:0006261 17 0.038
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.038
covalent chromatin modification GO:0016569 106 0.037
regulation of programmed cell death GO:0043067 152 0.037
negative regulation of cell communication GO:0010648 223 0.037
immune response GO:0006955 246 0.036
programmed cell death GO:0012501 257 0.036
purine nucleotide catabolic process GO:0006195 109 0.035
regulation of response to stress GO:0080134 200 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
single organism biosynthetic process GO:0044711 206 0.035
positive regulation of programmed cell death GO:0043068 62 0.034
small gtpase mediated signal transduction GO:0007264 88 0.033
stress activated protein kinase signaling cascade GO:0031098 55 0.033
response to ionizing radiation GO:0010212 32 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
nucleoside catabolic process GO:0009164 112 0.032
cellular protein modification process GO:0006464 438 0.032
regulation of cell division GO:0051302 72 0.031
organophosphate metabolic process GO:0019637 195 0.031
purine nucleoside catabolic process GO:0006152 112 0.031
germarium derived egg chamber formation GO:0007293 101 0.031
mitotic nuclear division GO:0007067 213 0.031
response to radiation GO:0009314 155 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.030
regulation of small gtpase mediated signal transduction GO:0051056 93 0.030
cell cycle phase transition GO:0044770 140 0.029
central nervous system development GO:0007417 201 0.029
histone modification GO:0016570 106 0.029
regulation of dna repair GO:0006282 5 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
telomere organization GO:0032200 21 0.028
nucleoside triphosphate metabolic process GO:0009141 120 0.028
dorsal ventral axis specification GO:0009950 66 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
brain development GO:0007420 120 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
positive regulation of endopeptidase activity GO:0010950 26 0.027
purine nucleoside monophosphate catabolic process GO:0009128 38 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
regionalization GO:0003002 416 0.026
positive regulation of molecular function GO:0044093 136 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
regulation of cytoskeleton organization GO:0051493 89 0.026
organic cyclic compound catabolic process GO:1901361 168 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
regulation of cell size GO:0008361 63 0.025
positive regulation of apoptotic process GO:0043065 47 0.025
chromatin silencing GO:0006342 76 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.025
response to organonitrogen compound GO:0010243 75 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
Human
glycosyl compound catabolic process GO:1901658 112 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
reproductive structure development GO:0048608 74 0.023
purine nucleoside monophosphate metabolic process GO:0009126 50 0.023
regulation of growth GO:0040008 233 0.023
single organism intracellular transport GO:1902582 207 0.022
negative regulation of signal transduction GO:0009968 206 0.022
immune system process GO:0002376 347 0.022
cell aging GO:0007569 2 0.022
dna integrity checkpoint GO:0031570 81 0.022
centrosome duplication GO:0051298 121 0.021
positive regulation of cell death GO:0010942 69 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
protein complex assembly GO:0006461 200 0.021
response to nitrogen compound GO:1901698 90 0.021
protein modification process GO:0036211 438 0.021
response to gamma radiation GO:0010332 17 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.019
ion transport GO:0006811 145 0.019
dendrite development GO:0016358 204 0.019
jnk cascade GO:0007254 50 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
organophosphate catabolic process GO:0046434 112 0.018
cellular response to organic substance GO:0071310 132 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
macromolecular complex assembly GO:0065003 256 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
negative regulation of signaling GO:0023057 219 0.018
response to external biotic stimulus GO:0043207 293 0.018
nuclear transport GO:0051169 72 0.017
immune response activating signal transduction GO:0002757 2 0.017
gtp catabolic process GO:0006184 72 0.017
germarium derived oocyte fate determination GO:0007294 26 0.017
compound eye morphogenesis GO:0001745 249 0.017
regulation of cell proliferation GO:0042127 163 0.016
centrosome cycle GO:0007098 137 0.016
proteolysis GO:0006508 192 0.016
purine containing compound catabolic process GO:0072523 112 0.016
cell cycle checkpoint GO:0000075 95 0.016
sister chromatid segregation GO:0000819 92 0.016
wing disc morphogenesis GO:0007472 344 0.016
macromolecule catabolic process GO:0009057 161 0.016
anatomical structure homeostasis GO:0060249 97 0.015
regulation of apoptotic process GO:0042981 130 0.015
response to biotic stimulus GO:0009607 294 0.015
muscle structure development GO:0061061 224 0.015
locomotory behavior GO:0007626 176 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
single organism membrane organization GO:0044802 93 0.014
positive regulation of immune system process GO:0002684 68 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
Human
alternative mrna splicing via spliceosome GO:0000380 60 0.014
aggressive behavior GO:0002118 63 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
monocarboxylic acid transport GO:0015718 3 0.013
sensory perception of pain GO:0019233 4 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
nucleoside monophosphate catabolic process GO:0009125 39 0.013
protein complex biogenesis GO:0070271 201 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
regulation of rna splicing GO:0043484 69 0.013
nucleoside metabolic process GO:0009116 127 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
Human
protein localization GO:0008104 284 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
mushroom body development GO:0016319 70 0.013
defense response GO:0006952 300 0.012
establishment of tissue polarity GO:0007164 87 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
syncytium formation GO:0006949 43 0.012
establishment of ommatidial planar polarity GO:0042067 49 0.011
purine containing compound metabolic process GO:0072521 155 0.011
ras protein signal transduction GO:0007265 88 0.011
positive regulation of growth GO:0045927 75 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
small molecule metabolic process GO:0044281 305 0.011
regulation of cell differentiation GO:0045595 302 0.011
dna amplification GO:0006277 11 0.011
positive regulation of gene expression GO:0010628 290 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
intra s dna damage checkpoint GO:0031573 2 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
gonad development GO:0008406 50 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
positive regulation of signaling GO:0023056 243 0.010
forebrain development GO:0030900 2 0.010
development of primary sexual characteristics GO:0045137 50 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
negative regulation of nervous system development GO:0051961 92 0.010

RecQ5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system cancer DOID:0060100 0 0.021
thoracic cancer DOID:5093 0 0.015
disease of metabolism DOID:0014667 0 0.013