Drosophila melanogaster

9 known processes

Ca-alpha1D (Dmel_CG4894)

Ca[2+]-channel protein alpha[[1]] subunit D

(Aliases: Ca-a1D,l(2)35Fa,l35Fa,DroCa1,Ca-alpha1,alpha1D,BG:DS02795.1,CG4894,Ca-_1D,alpha1,DmCa1D,DmCa1alpha1,Dmca1D,Dmel\CG4894)

Ca-alpha1D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 0.988
Mouse
neuron projection guidance GO:0097485 241 0.977
axon guidance GO:0007411 233 0.973
axon development GO:0061564 297 0.954
Mouse
chemotaxis GO:0006935 249 0.924
synapse organization GO:0050808 196 0.923
Zebrafish Mouse Fly
taxis GO:0042330 304 0.921
motor neuron axon guidance GO:0008045 58 0.845
neuromuscular junction development GO:0007528 149 0.806
Mouse Fly
muscle structure development GO:0061061 224 0.691
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.486
Fly
regulation of neurogenesis GO:0050767 158 0.418
growth GO:0040007 359 0.417
Mouse Fly
developmental growth GO:0048589 280 0.398
Mouse Fly
synaptic growth at neuromuscular junction GO:0051124 119 0.362
Fly
regulation of multicellular organismal development GO:2000026 414 0.358
Fly
regulation of nervous system development GO:0051960 248 0.298
Fly
developmental growth involved in morphogenesis GO:0060560 65 0.289
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.281
regulation of neuron differentiation GO:0045664 103 0.279
transcription from rna polymerase ii promoter GO:0006366 368 0.254
neuromuscular synaptic transmission GO:0007274 67 0.250
positive regulation of cellular biosynthetic process GO:0031328 316 0.239
synaptic transmission GO:0007268 288 0.226
Mouse Fly
synapse assembly GO:0007416 143 0.222
Fly
establishment of localization in cell GO:0051649 402 0.210
Mouse Fly
muscle organ development GO:0007517 127 0.193
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.176
small molecule metabolic process GO:0044281 305 0.169
regulation of synapse structure and activity GO:0050803 128 0.164
Fly
regulation of developmental growth GO:0048638 174 0.148
Mouse Fly
hindbrain development GO:0030902 2 0.145
regulation of cell differentiation GO:0045595 302 0.143
positive regulation of transport GO:0051050 92 0.137
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.134
protein localization GO:0008104 284 0.133
negative regulation of rna metabolic process GO:0051253 251 0.131
embryonic organ development GO:0048568 50 0.123
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.118
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.116
forebrain development GO:0030900 2 0.116
regulation of cellular localization GO:0060341 136 0.115
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.114
intracellular signal transduction GO:0035556 300 0.110
learning or memory GO:0007611 141 0.109
Mouse
regulation of behavior GO:0050795 75 0.105
Worm
ameboidal type cell migration GO:0001667 151 0.101
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.098
regulation of transport GO:0051049 181 0.094
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular component biogenesis GO:0044087 201 0.090
Fly
axon midline choice point recognition GO:0016199 26 0.090
muscle cell differentiation GO:0042692 103 0.088
Mouse
myofibril assembly GO:0030239 36 0.086
macromolecular complex assembly GO:0065003 256 0.086
cell division GO:0051301 248 0.086
neuron projection extension GO:1990138 32 0.085
developmental maturation GO:0021700 172 0.083
cell maturation GO:0048469 144 0.083
regulation of synapse assembly GO:0051963 94 0.082
Fly
positive regulation of gene expression GO:0010628 290 0.081
regulation of cell development GO:0060284 215 0.078
axon extension GO:0048675 32 0.078
positive regulation of transcription dna templated GO:0045893 266 0.076
immune system process GO:0002376 347 0.076
negative regulation of biosynthetic process GO:0009890 277 0.076
brain development GO:0007420 120 0.076
establishment of vesicle localization GO:0051650 51 0.074
glial cell migration GO:0008347 31 0.074
olfactory learning GO:0008355 56 0.074
negative regulation of gene expression GO:0010629 387 0.073
positive regulation of macromolecule metabolic process GO:0010604 405 0.072
kidney development GO:0001822 3 0.071
regulation of synapse organization GO:0050807 110 0.068
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.067
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.066
negative regulation of cellular metabolic process GO:0031324 382 0.066
programmed cell death GO:0012501 257 0.066
anatomical structure homeostasis GO:0060249 97 0.064
epithelium migration GO:0090132 148 0.063
positive regulation of signaling GO:0023056 243 0.062
carboxylic acid metabolic process GO:0019752 92 0.061
regulation of phosphate metabolic process GO:0019220 210 0.060
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.060
regulation of cell cycle GO:0051726 291 0.058
protein complex biogenesis GO:0070271 201 0.058
heart development GO:0007507 82 0.057
Zebrafish
head development GO:0060322 135 0.056
regulation of cell cycle process GO:0010564 181 0.055
biological adhesion GO:0022610 138 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.053
cation transmembrane transport GO:0098655 88 0.050
Human Zebrafish Mouse Rat Worm Fly
cell adhesion GO:0007155 136 0.048
regulation of axon extension involved in axon guidance GO:0048841 4 0.048
retinal ganglion cell axon guidance GO:0031290 12 0.048
tripartite regional subdivision GO:0007351 103 0.047
body morphogenesis GO:0010171 2 0.045
cellular protein complex disassembly GO:0043624 35 0.045
cell migration GO:0016477 238 0.045
catabolic process GO:0009056 409 0.044
regulation of neuron projection development GO:0010975 69 0.043
respiratory system development GO:0060541 213 0.043
anterior posterior axis specification embryo GO:0008595 103 0.043
positive regulation of cellular component biogenesis GO:0044089 80 0.043
Fly
single organism biosynthetic process GO:0044711 206 0.043
regulation of embryonic development GO:0045995 68 0.043
regulation of synaptic transmission GO:0050804 69 0.043
Fly
epithelial cell migration GO:0010631 148 0.042
regulation of localization GO:0032879 275 0.042
Human Zebrafish Mouse Rat Worm Fly
regulation of cell size GO:0008361 63 0.042
embryo development ending in birth or egg hatching GO:0009792 152 0.042
Zebrafish
regulation of molecular function GO:0065009 217 0.041
Mouse
nuclear division GO:0000280 332 0.041
camera type eye development GO:0043010 4 0.041
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.040
skeletal muscle organ development GO:0060538 48 0.040
Mouse
eye photoreceptor cell development GO:0042462 81 0.039
regulation of chemotaxis GO:0050920 12 0.039
vesicle mediated transport GO:0016192 381 0.039
Mouse Fly
neurotransmitter secretion GO:0007269 35 0.039
Fly
protein complex assembly GO:0006461 200 0.039
oxoacid metabolic process GO:0043436 103 0.039
cell proliferation GO:0008283 299 0.038
positive regulation of biosynthetic process GO:0009891 316 0.038
positive regulation of rna metabolic process GO:0051254 271 0.038
rhythmic process GO:0048511 106 0.037
neurotransmitter transport GO:0006836 37 0.037
Fly
open tracheal system development GO:0007424 204 0.037
regulation of catalytic activity GO:0050790 185 0.036
cell junction assembly GO:0034329 42 0.036
single organism membrane organization GO:0044802 93 0.036
multi multicellular organism process GO:0044706 123 0.035
Worm Fly
negative regulation of response to stimulus GO:0048585 258 0.035
sensory organ morphogenesis GO:0090596 260 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.034
regulation of programmed cell death GO:0043067 152 0.034
regulation of cytoskeleton organization GO:0051493 89 0.034
negative regulation of signal transduction GO:0009968 206 0.034
embryonic axis specification GO:0000578 107 0.034
embryonic morphogenesis GO:0048598 206 0.034
Zebrafish
regulation of anatomical structure size GO:0090066 163 0.032
Mouse
epithelial cell differentiation GO:0030855 322 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
neuron maturation GO:0042551 31 0.031
male courtship behavior veined wing generated song production GO:0045433 20 0.031
Fly
organic acid metabolic process GO:0006082 103 0.031
localization of cell GO:0051674 257 0.031
adult behavior GO:0030534 137 0.031
Mouse Fly
retina development in camera type eye GO:0060041 4 0.031
Mouse
regulation of growth GO:0040008 233 0.031
Mouse Fly
regulation of mapk cascade GO:0043408 92 0.031
single organism cell adhesion GO:0098602 47 0.031
regulation of organelle organization GO:0033043 196 0.031
cellular component assembly involved in morphogenesis GO:0010927 151 0.031
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
negative regulation of cell differentiation GO:0045596 143 0.030
death GO:0016265 284 0.030
regulation of cell projection organization GO:0031344 92 0.029
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
nucleotide metabolic process GO:0009117 161 0.029
organonitrogen compound biosynthetic process GO:1901566 117 0.029
single organismal cell cell adhesion GO:0016337 45 0.028
cellular ketone metabolic process GO:0042180 24 0.028
connective tissue development GO:0061448 3 0.027
lipid metabolic process GO:0006629 121 0.027
multicellular organismal reproductive behavior GO:0033057 110 0.027
Worm Fly
axon extension involved in axon guidance GO:0048846 10 0.027
organelle fission GO:0048285 340 0.027
cellular protein modification process GO:0006464 438 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
dna metabolic process GO:0006259 227 0.027
regulation of cell death GO:0010941 173 0.027
humoral immune response GO:0006959 117 0.027
single organism cellular localization GO:1902580 180 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
detection of stimulus involved in sensory perception GO:0050906 92 0.026
Zebrafish Fly
protein modification process GO:0036211 438 0.026
telencephalon development GO:0021537 2 0.026
regulation of epithelial cell proliferation GO:0050678 4 0.026
regulation of secretion GO:0051046 44 0.026
Fly
erbb signaling pathway GO:0038127 58 0.025
negative regulation of cell communication GO:0010648 223 0.024
dendrite development GO:0016358 204 0.024
Mouse
response to alcohol GO:0097305 95 0.024
developmental cell growth GO:0048588 52 0.024
gene silencing GO:0016458 138 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
tube morphogenesis GO:0035239 191 0.024
response to organic substance GO:0010033 284 0.024
homeostatic process GO:0042592 199 0.024
Human Mouse
actomyosin structure organization GO:0031032 56 0.024
pyridine nucleotide metabolic process GO:0019362 2 0.023
secretion GO:0046903 109 0.023
Mouse Fly
apoptotic process GO:0006915 159 0.023
determination of ventral identity GO:0048264 1 0.023
dendrite guidance GO:0070983 21 0.023
inositol lipid mediated signaling GO:0048017 4 0.023
r7 cell differentiation GO:0045466 43 0.023
regulation of cellular component size GO:0032535 98 0.023
peripheral nervous system development GO:0007422 52 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
cellular macromolecule localization GO:0070727 220 0.022
striated muscle cell development GO:0055002 50 0.022
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.022
response to wounding GO:0009611 94 0.022
morphogenesis of a branching structure GO:0001763 45 0.022
regulation of synaptic activity GO:0060025 9 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
axon choice point recognition GO:0016198 26 0.022
cell death GO:0008219 279 0.021
inorganic cation transmembrane transport GO:0098662 61 0.021
Human Zebrafish Mouse Rat Worm Fly
central nervous system neuron differentiation GO:0021953 8 0.021
photoreceptor cell development GO:0042461 96 0.021
regulation of neuromuscular synaptic transmission GO:1900073 15 0.021
positive regulation of growth GO:0045927 75 0.021
Fly
gliogenesis GO:0042063 80 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
stem cell differentiation GO:0048863 117 0.020
tube development GO:0035295 244 0.020
striated muscle cell differentiation GO:0051146 90 0.020
Mouse
mating GO:0007618 120 0.020
Fly
organophosphate metabolic process GO:0019637 195 0.020
nitrogen compound transport GO:0071705 85 0.020
Mouse
striated muscle myosin thick filament assembly GO:0071688 3 0.020
macromolecular complex disassembly GO:0032984 37 0.020
metal ion transport GO:0030001 74 0.020
Human Zebrafish Mouse Rat Worm Fly
regulation of actin filament based process GO:0032970 42 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
cell recognition GO:0008037 102 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
axonal defasciculation GO:0007414 12 0.019
cell cycle phase transition GO:0044770 140 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
epithelial cell development GO:0002064 274 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
epithelial cell migration open tracheal system GO:0007427 32 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
photoreceptor cell axon guidance GO:0072499 23 0.018
dna repair GO:0006281 54 0.018
tissue migration GO:0090130 155 0.018
purine containing compound metabolic process GO:0072521 155 0.018
cell cycle checkpoint GO:0000075 95 0.018
negative regulation of signaling GO:0023057 219 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
regulation of phosphorylation GO:0042325 147 0.018
cellular protein complex assembly GO:0043623 71 0.018
mushroom body development GO:0016319 70 0.018
female gonad development GO:0008585 12 0.018
glial cell differentiation GO:0010001 35 0.017
positive regulation of cell communication GO:0010647 250 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
circulatory system development GO:0072359 82 0.016
Zebrafish
regulation of organ morphogenesis GO:2000027 78 0.016
regulation of cell division GO:0051302 72 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
Human Zebrafish Mouse Rat Worm Fly
regulation of multi organism process GO:0043900 131 0.016
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
glial cell development GO:0021782 27 0.016
larval somatic muscle development GO:0007526 19 0.016
muscle cell development GO:0055001 50 0.016
Mouse
protein maturation GO:0051604 71 0.016
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.016
olfactory bulb axon guidance GO:0071678 3 0.015
gland morphogenesis GO:0022612 145 0.015
branching involved in open tracheal system development GO:0060446 45 0.015
lateral inhibition GO:0046331 206 0.015
segmentation GO:0035282 207 0.015
positive regulation of axonogenesis GO:0050772 2 0.015
protein phosphorylation GO:0006468 169 0.015
regulation of vesicle mediated transport GO:0060627 59 0.015
camera type eye morphogenesis GO:0048593 2 0.015
neuron recognition GO:0008038 101 0.015
protein polymerization GO:0051258 42 0.015
cellular catabolic process GO:0044248 372 0.015
innate immune response GO:0045087 144 0.015
reproductive system development GO:0061458 74 0.015
Worm
protein processing GO:0016485 68 0.015
mitotic nuclear division GO:0007067 213 0.014
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.014
response to other organism GO:0051707 293 0.014
endomembrane system organization GO:0010256 119 0.014
Mouse
cellular protein localization GO:0034613 160 0.014
regulation of nuclear division GO:0051783 58 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
negative regulation of nervous system development GO:0051961 92 0.014
endocytosis GO:0006897 310 0.014
regulation of protein localization GO:0032880 76 0.014
response to radiation GO:0009314 155 0.014
Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
regulation of protein polymerization GO:0032271 28 0.014
peptidyl amino acid modification GO:0018193 105 0.014
organelle assembly GO:0070925 198 0.014
immune system development GO:0002520 57 0.014
ovarian follicle cell migration GO:0007297 121 0.014
rhythmic behavior GO:0007622 76 0.014
regulation of cellular component movement GO:0051270 42 0.014
light adaption GO:0036367 3 0.014
trachea development GO:0060438 29 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regionalization GO:0003002 416 0.014
anterior posterior axis specification GO:0009948 109 0.014
axis elongation GO:0003401 3 0.014
actin cytoskeleton organization GO:0030036 206 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
mapk cascade GO:0000165 107 0.013
positive regulation of cell migration GO:0030335 2 0.013
stem cell development GO:0048864 79 0.013
regulation of photoreceptor cell axon guidance GO:2000289 5 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.013
central nervous system development GO:0007417 201 0.013
dna methylation or demethylation GO:0044728 4 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
synaptic vesicle transport GO:0048489 50 0.013
germ band shortening GO:0007390 19 0.013
phosphorylation GO:0016310 294 0.013
positive regulation of axon extension GO:0045773 2 0.013
regulation of locomotion GO:0040012 42 0.013
regulation of endocytosis GO:0030100 37 0.013
regulation of gene silencing GO:0060968 63 0.012
response to biotic stimulus GO:0009607 294 0.012
nucleoside catabolic process GO:0009164 112 0.012
organic substance transport GO:0071702 257 0.012
Mouse
cell fate specification GO:0001708 71 0.012
cell junction organization GO:0034330 57 0.012
bmp signaling pathway GO:0030509 27 0.012
extracellular structure organization GO:0043062 46 0.012
protein depolymerization GO:0051261 31 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
oviposition GO:0018991 19 0.012
Worm
negative regulation of multicellular organismal process GO:0051241 142 0.012
organelle localization GO:0051640 148 0.012
positive regulation of molecular function GO:0044093 136 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
positive regulation of nervous system development GO:0051962 69 0.012
Fly
transmission of nerve impulse GO:0019226 12 0.011
positive regulation of synaptic transmission GO:0050806 15 0.011
cell motility GO:0048870 251 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
cellular homeostasis GO:0019725 80 0.011
Human Mouse
organic substance catabolic process GO:1901575 308 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
detection of stimulus GO:0051606 156 0.011
Zebrafish Fly
eye photoreceptor cell differentiation GO:0001754 145 0.011
branch fusion open tracheal system GO:0035147 17 0.011
regulation of neuronal synaptic plasticity GO:0048168 8 0.011
phagocytosis GO:0006909 215 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
negative regulation of organelle organization GO:0010639 56 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
compound eye photoreceptor development GO:0042051 78 0.011
golgi to plasma membrane protein transport GO:0043001 8 0.011
morphogenesis of a branching epithelium GO:0061138 45 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
nerve development GO:0021675 6 0.011
positive regulation of developmental process GO:0051094 143 0.011
Fly
oocyte differentiation GO:0009994 145 0.011
determination of dorsal ventral asymmetry GO:0048262 3 0.011
imaginal disc growth GO:0007446 37 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
cation transport GO:0006812 110 0.011
Human Zebrafish Mouse Rat Worm Fly
regulation of protein depolymerization GO:1901879 27 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
immune response GO:0006955 246 0.010
negative regulation of synapse assembly GO:0051964 39 0.010
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of chromatin silencing GO:0031935 36 0.010
regulation of hydrolase activity GO:0051336 97 0.010
amine metabolic process GO:0009308 12 0.010
axis specification GO:0009798 167 0.010
muscle attachment GO:0016203 36 0.010
larval development GO:0002164 104 0.010
detection of chemical stimulus GO:0009593 93 0.010
regulation of axon guidance GO:1902667 10 0.010
organ growth GO:0035265 56 0.010
Mouse
appendage development GO:0048736 401 0.010

Ca-alpha1D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.099
Human
nervous system disease DOID:863 0 0.022
cardiovascular system disease DOID:1287 0 0.013
Human