Drosophila melanogaster

174 known processes

POSH (Dmel_CG4909)

Plenty of SH3s

(Aliases: BEST:GM09451,155116_at,Dmel\CG4909,posh,DPOSH,dPOSH,CG4909,GM09451,l(2)k15815)

POSH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to fungus GO:0050832 48 0.949
defense response GO:0006952 300 0.940
vesicle mediated transport GO:0016192 381 0.831
morphogenesis of a polarized epithelium GO:0001738 93 0.807
nuclear division GO:0000280 332 0.759
morphogenesis of an epithelium GO:0002009 276 0.754
response to fungus GO:0009620 50 0.746
embryo development ending in birth or egg hatching GO:0009792 152 0.714
negative regulation of cell communication GO:0010648 223 0.672
Human
multicellular organismal aging GO:0010259 140 0.664
determination of adult lifespan GO:0008340 137 0.655
establishment of planar polarity GO:0001736 87 0.654
appendage morphogenesis GO:0035107 397 0.649
endocytosis GO:0006897 310 0.647
embryonic development via the syncytial blastoderm GO:0001700 148 0.641
epidermis development GO:0008544 65 0.620
aging GO:0007568 143 0.583
wing disc morphogenesis GO:0007472 344 0.569
establishment of localization in cell GO:0051649 402 0.496
compound eye morphogenesis GO:0001745 249 0.486
axon development GO:0061564 297 0.484
negative regulation of signaling GO:0023057 219 0.473
Human
regulation of localization GO:0032879 275 0.471
cellular protein localization GO:0034613 160 0.470
regulation of cell cycle GO:0051726 291 0.465
positive regulation of response to stimulus GO:0048584 323 0.465
establishment or maintenance of cell polarity GO:0007163 167 0.463
positive regulation of macromolecule metabolic process GO:0010604 405 0.455
axon guidance GO:0007411 233 0.388
nuclear transport GO:0051169 72 0.383
protein localization GO:0008104 284 0.376
appendage development GO:0048736 401 0.375
epithelial cell differentiation GO:0030855 322 0.363
post embryonic appendage morphogenesis GO:0035120 385 0.359
imaginal disc derived appendage morphogenesis GO:0035114 395 0.344
intracellular signal transduction GO:0035556 300 0.327
catabolic process GO:0009056 409 0.314
regulation of protein metabolic process GO:0051246 256 0.307
Human
cellular macromolecule localization GO:0070727 220 0.284
imaginal disc derived wing morphogenesis GO:0007476 337 0.284
imaginal disc derived appendage development GO:0048737 399 0.276
dendrite morphogenesis GO:0048813 199 0.275
tissue morphogenesis GO:0048729 297 0.257
regulation of cellular localization GO:0060341 136 0.256
eye development GO:0001654 323 0.253
regulation of antibacterial peptide production GO:0002786 22 0.250
cellular response to dna damage stimulus GO:0006974 223 0.247
response to radiation GO:0009314 155 0.235
immune system process GO:0002376 347 0.234
antibacterial humoral response GO:0019731 44 0.231
defense response to bacterium GO:0042742 178 0.228
axis specification GO:0009798 167 0.224
immune response regulating signaling pathway GO:0002764 2 0.222
single organism intracellular transport GO:1902582 207 0.220
defense response to other organism GO:0098542 225 0.218
regulation of jnk cascade GO:0046328 40 0.199
single organism cellular localization GO:1902580 180 0.199
regulation of phosphate metabolic process GO:0019220 210 0.195
establishment of monopolar cell polarity GO:0061162 15 0.193
response to organic substance GO:0010033 284 0.193
embryonic morphogenesis GO:0048598 206 0.188
regulation of cellular response to stress GO:0080135 89 0.185
response to oxygen containing compound GO:1901700 200 0.181
immune effector process GO:0002252 98 0.178
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.162
negative regulation of response to stimulus GO:0048585 258 0.159
Human
establishment of tissue polarity GO:0007164 87 0.158
eggshell formation GO:0030703 105 0.158
neuron projection guidance GO:0097485 241 0.156
dna biosynthetic process GO:0071897 24 0.151
taxis GO:0042330 304 0.142
negative regulation of signal transduction GO:0009968 206 0.139
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.135
nucleotide metabolic process GO:0009117 161 0.134
compound eye development GO:0048749 307 0.130
establishment of protein localization GO:0045184 163 0.129
response to biotic stimulus GO:0009607 294 0.125
regulation of multicellular organismal development GO:2000026 414 0.124
peptide metabolic process GO:0006518 80 0.118
positive regulation of humoral immune response GO:0002922 28 0.114
hair cell differentiation GO:0035315 47 0.114
protein transport GO:0015031 155 0.113
negative regulation of cellular metabolic process GO:0031324 382 0.112
Human
cell division GO:0051301 248 0.112
cell death GO:0008219 279 0.111
organic substance transport GO:0071702 257 0.110
regionalization GO:0003002 416 0.110
actin cytoskeleton organization GO:0030036 206 0.109
signal transduction by phosphorylation GO:0023014 107 0.107
response to light stimulus GO:0009416 124 0.106
tissue homeostasis GO:0001894 36 0.105
ion transport GO:0006811 145 0.105
jnk cascade GO:0007254 50 0.105
cellular protein complex assembly GO:0043623 71 0.103
ovarian follicle cell development GO:0030707 248 0.098
positive regulation of catabolic process GO:0009896 105 0.097
regulation of intracellular signal transduction GO:1902531 236 0.097
dorsal ventral pattern formation GO:0009953 133 0.097
regulation of phosphorus metabolic process GO:0051174 210 0.096
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.096
protein localization to organelle GO:0033365 82 0.094
secretion GO:0046903 109 0.093
regulation of response to stress GO:0080134 200 0.093
regulation of nucleocytoplasmic transport GO:0046822 35 0.091
phagocytosis GO:0006909 215 0.091
intracellular protein transport GO:0006886 104 0.090
negative regulation of intracellular signal transduction GO:1902532 57 0.085
regulation of immune system process GO:0002682 176 0.082
intracellular transport GO:0046907 228 0.081
cell proliferation GO:0008283 299 0.080
positive regulation of protein metabolic process GO:0051247 128 0.079
maintenance of location GO:0051235 73 0.077
organonitrogen compound metabolic process GO:1901564 318 0.076
regulation of mitotic cell cycle GO:0007346 190 0.076
nucleobase containing compound catabolic process GO:0034655 165 0.075
anterior posterior axis specification GO:0009948 109 0.074
regulation of molecular function GO:0065009 217 0.074
Human
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.074
tube development GO:0035295 244 0.073
proteasomal protein catabolic process GO:0010498 59 0.071
negative regulation of gene expression GO:0010629 387 0.071
Human
hemopoiesis GO:0030097 46 0.070
negative regulation of growth GO:0045926 84 0.066
epidermal cell differentiation GO:0009913 51 0.066
chemotaxis GO:0006935 249 0.066
positive regulation of cellular component organization GO:0051130 156 0.065
cellular component assembly involved in morphogenesis GO:0010927 151 0.065
ommatidial rotation GO:0016318 20 0.063
biological adhesion GO:0022610 138 0.063
anatomical structure homeostasis GO:0060249 97 0.062
regulation of cell cycle process GO:0010564 181 0.062
tissue migration GO:0090130 155 0.062
columnar cuboidal epithelial cell development GO:0002066 249 0.062
regulation of protein kinase activity GO:0045859 51 0.061
chromosome organization GO:0051276 360 0.060
spindle organization GO:0007051 253 0.060
dna integrity checkpoint GO:0031570 81 0.060
nuclear import GO:0051170 51 0.058
mapk cascade GO:0000165 107 0.058
immune response activating signal transduction GO:0002757 2 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
ribose phosphate metabolic process GO:0019693 145 0.058
establishment of ommatidial planar polarity GO:0042067 49 0.057
regulation of transport GO:0051049 181 0.057
phosphorylation GO:0016310 294 0.057
positive regulation of gtpase activity GO:0043547 43 0.056
secretion by cell GO:0032940 101 0.056
axonogenesis GO:0007409 290 0.056
larval development GO:0002164 104 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.055
Human
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.054
male gamete generation GO:0048232 201 0.054
regulation of establishment of planar polarity GO:0090175 22 0.054
regulation of protein phosphorylation GO:0001932 64 0.054
positive regulation of signaling GO:0023056 243 0.053
extracellular structure organization GO:0043062 46 0.053
regulation of cell morphogenesis GO:0022604 163 0.053
cation transport GO:0006812 110 0.052
cellular macromolecule catabolic process GO:0044265 136 0.051
cell junction assembly GO:0034329 42 0.050
cellular amide metabolic process GO:0043603 80 0.050
nitrogen compound transport GO:0071705 85 0.050
regulation of intracellular transport GO:0032386 64 0.049
regulation of stress activated mapk cascade GO:0032872 41 0.048
hematopoietic or lymphoid organ development GO:0048534 57 0.048
mitotic nuclear division GO:0007067 213 0.047
wound healing GO:0042060 75 0.046
stress activated mapk cascade GO:0051403 52 0.046
eye morphogenesis GO:0048592 260 0.045
response to external biotic stimulus GO:0043207 293 0.045
organophosphate metabolic process GO:0019637 195 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.044
wnt signaling pathway GO:0016055 98 0.044
nucleocytoplasmic transport GO:0006913 72 0.044
regulation of anatomical structure size GO:0090066 163 0.044
regulation of actin filament based process GO:0032970 42 0.044
dendrite development GO:0016358 204 0.044
purine nucleotide metabolic process GO:0006163 146 0.043
positive regulation of developmental process GO:0051094 143 0.043
enzyme linked receptor protein signaling pathway GO:0007167 179 0.042
multicellular organismal homeostasis GO:0048871 41 0.042
digestive tract development GO:0048565 149 0.041
ribonucleoside metabolic process GO:0009119 127 0.041
immune system development GO:0002520 57 0.041
negative regulation of mitotic cell cycle GO:0045930 109 0.041
regulation of protein localization GO:0032880 76 0.040
epithelial cell development GO:0002064 274 0.040
regulation of mitotic cell cycle phase transition GO:1901990 130 0.040
negative regulation of phosphorylation GO:0042326 35 0.039
protein targeting GO:0006605 64 0.038
regulation of immune response GO:0050776 118 0.038
single organism catabolic process GO:0044712 228 0.038
glycosyl compound metabolic process GO:1901657 127 0.038
regulation of axonogenesis GO:0050770 32 0.037
cuticle pigmentation GO:0048067 22 0.037
ovarian follicle cell migration GO:0007297 121 0.037
regulation of proteolysis GO:0030162 87 0.037
Human
somatic stem cell division GO:0048103 37 0.036
ribonucleoside catabolic process GO:0042454 112 0.036
cell motility GO:0048870 251 0.035
regulation of humoral immune response GO:0002920 51 0.035
positive regulation of transport GO:0051050 92 0.035
photoreceptor cell differentiation GO:0046530 170 0.034
respiratory system development GO:0060541 213 0.034
negative regulation of cell differentiation GO:0045596 143 0.034
protein acetylation GO:0006473 39 0.033
cellular catabolic process GO:0044248 372 0.033
open tracheal system development GO:0007424 204 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.033
purine ribonucleoside metabolic process GO:0046128 127 0.033
macromolecule catabolic process GO:0009057 161 0.033
connective tissue development GO:0061448 3 0.032
eggshell chorion gene amplification GO:0007307 9 0.032
aromatic compound catabolic process GO:0019439 166 0.032
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.032
positive regulation of response to biotic stimulus GO:0002833 31 0.032
central nervous system development GO:0007417 201 0.032
secondary metabolic process GO:0019748 75 0.032
protein modification process GO:0036211 438 0.032
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.032
notch signaling pathway GO:0007219 120 0.031
regulation of immune effector process GO:0002697 52 0.031
muscle structure development GO:0061061 224 0.031
negative regulation of cell cycle phase transition GO:1901988 103 0.031
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.030
regulation of phosphorylation GO:0042325 147 0.030
dna metabolic process GO:0006259 227 0.030
sensory organ morphogenesis GO:0090596 260 0.030
limb morphogenesis GO:0035108 1 0.030
organonitrogen compound catabolic process GO:1901565 128 0.030
actomyosin structure organization GO:0031032 56 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.029
positive regulation of cellular catabolic process GO:0031331 95 0.029
polarized epithelial cell differentiation GO:0030859 10 0.029
cuticle development GO:0042335 86 0.029
regulation of organ morphogenesis GO:2000027 78 0.029
organonitrogen compound biosynthetic process GO:1901566 117 0.029
small molecule metabolic process GO:0044281 305 0.028
purine ribonucleotide metabolic process GO:0009150 145 0.028
antibacterial peptide biosynthetic process GO:0002780 22 0.028
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.028
purine ribonucleotide catabolic process GO:0009154 109 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.028
regulation of cell cycle phase transition GO:1901987 130 0.028
regulation of wnt signaling pathway GO:0030111 68 0.028
cell recognition GO:0008037 102 0.028
negative regulation of molecular function GO:0044092 51 0.028
Human
nucleotide catabolic process GO:0009166 109 0.028
positive regulation of multicellular organismal process GO:0051240 143 0.028
protein phosphorylation GO:0006468 169 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
convergent extension GO:0060026 2 0.027
instar larval development GO:0002168 55 0.027
protein localization to nucleus GO:0034504 55 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
tripartite regional subdivision GO:0007351 103 0.026
purine nucleoside catabolic process GO:0006152 112 0.026
response to wounding GO:0009611 94 0.026
metal ion transport GO:0030001 74 0.026
production of molecular mediator of immune response GO:0002440 46 0.026
response to abiotic stimulus GO:0009628 341 0.026
negative regulation of phosphate metabolic process GO:0045936 45 0.026
skin development GO:0043588 65 0.026
regulation of programmed cell death GO:0043067 152 0.026
Human
localization of cell GO:0051674 257 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.025
cell migration GO:0016477 238 0.025
regulation of antimicrobial humoral response GO:0002759 50 0.025
negative regulation of notch signaling pathway GO:0045746 41 0.025
positive regulation of signal transduction GO:0009967 223 0.025
regulation of cytoplasmic transport GO:1903649 47 0.025
eye photoreceptor cell development GO:0042462 81 0.025
purine nucleoside metabolic process GO:0042278 127 0.025
peptide biosynthetic process GO:0043043 42 0.025
organic substance catabolic process GO:1901575 308 0.024
stress activated protein kinase signaling cascade GO:0031098 55 0.024
apoptotic process GO:0006915 159 0.024
Human
heterocycle catabolic process GO:0046700 166 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
camera type eye development GO:0043010 4 0.024
actin filament based process GO:0030029 220 0.024
antimicrobial peptide production GO:0002775 46 0.024
segmentation GO:0035282 207 0.024
imaginal disc fusion GO:0046528 19 0.024
ribonucleotide metabolic process GO:0009259 145 0.024
regulation of catabolic process GO:0009894 170 0.023
organelle fission GO:0048285 340 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
protein targeting to nucleus GO:0044744 51 0.023
regulation of protein catabolic process GO:0042176 55 0.023
organelle assembly GO:0070925 198 0.023
glycosyl compound catabolic process GO:1901658 112 0.023
organic hydroxy compound metabolic process GO:1901615 83 0.023
eggshell chorion assembly GO:0007306 66 0.022
regulation of establishment of protein localization GO:0070201 61 0.022
peptidyl threonine phosphorylation GO:0018107 2 0.022
dna damage checkpoint GO:0000077 78 0.022
purine containing compound metabolic process GO:0072521 155 0.022
humoral immune response GO:0006959 117 0.022
camera type eye morphogenesis GO:0048593 2 0.022
body morphogenesis GO:0010171 2 0.021
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.021
immune response GO:0006955 246 0.021
negative regulation of wnt signaling pathway GO:0030178 28 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
regulation of notch signaling pathway GO:0008593 100 0.021
purine containing compound catabolic process GO:0072523 112 0.021
hematopoietic progenitor cell differentiation GO:0002244 1 0.021
endomembrane system organization GO:0010256 119 0.021
anterior posterior axis specification embryo GO:0008595 103 0.021
organophosphate catabolic process GO:0046434 112 0.020
cell growth GO:0016049 108 0.020
regulation of cell differentiation GO:0045595 302 0.020
gastrulation GO:0007369 70 0.020
response to organonitrogen compound GO:0010243 75 0.020
spinal cord development GO:0021510 1 0.020
positive regulation of antimicrobial peptide production GO:0002225 28 0.020
innate immune response GO:0045087 144 0.020
negative regulation of phosphorus metabolic process GO:0010563 45 0.020
protein catabolic process GO:0030163 101 0.020
growth GO:0040007 359 0.019
chorion containing eggshell formation GO:0007304 105 0.019
regulation of transferase activity GO:0051338 58 0.019
programmed cell death GO:0012501 257 0.019
Human
regulation of map kinase activity GO:0043405 17 0.019
response to endogenous stimulus GO:0009719 119 0.019
positive regulation of protein localization to nucleus GO:1900182 21 0.019
cell fate determination GO:0001709 91 0.019
homeostatic process GO:0042592 199 0.019
regulation of mapk cascade GO:0043408 92 0.019
cellular component disassembly GO:0022411 46 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
positive regulation of immune response GO:0050778 63 0.018
regulation of protein transport GO:0051223 57 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
mitotic dna damage checkpoint GO:0044773 74 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.017
synaptic transmission GO:0007268 288 0.017
regulation of intracellular protein transport GO:0033157 46 0.017
salivary gland development GO:0007431 162 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
cellular response to endogenous stimulus GO:0071495 80 0.017
cellular response to organic substance GO:0071310 132 0.017
actin polymerization or depolymerization GO:0008154 31 0.017
protein import into nucleus GO:0006606 51 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
exocrine system development GO:0035272 162 0.016
positive regulation of histone acetylation GO:0035066 3 0.016
contractile actin filament bundle assembly GO:0030038 1 0.016
female genitalia development GO:0030540 6 0.016
response to peptide GO:1901652 29 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
cell cycle phase transition GO:0044770 140 0.016
nucleoside catabolic process GO:0009164 112 0.016
negative regulation of defense response GO:0031348 35 0.016
convergent extension involved in gastrulation GO:0060027 2 0.016
positive regulation of antimicrobial humoral response GO:0002760 28 0.015
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.015
establishment of protein localization to organelle GO:0072594 62 0.015
positive regulation of intracellular transport GO:0032388 42 0.015
nucleoside metabolic process GO:0009116 127 0.015
positive regulation of proteolysis GO:0045862 52 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
regulation of organelle organization GO:0033043 196 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
regulation of kinase activity GO:0043549 53 0.015
neuron recognition GO:0008038 101 0.015
regulation of locomotion GO:0040012 42 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
regulation of dendrite morphogenesis GO:0048814 28 0.015
regulation of catalytic activity GO:0050790 185 0.015
Human
response to oxidative stress GO:0006979 86 0.015
imaginal disc derived wing hair organization GO:0035317 45 0.015
regulation of response to external stimulus GO:0032101 115 0.014
regulation of nervous system development GO:0051960 248 0.014
cell aging GO:0007569 2 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
proteolysis GO:0006508 192 0.014
regulation of production of molecular mediator of immune response GO:0002700 44 0.014
positive regulation of protein transport GO:0051222 37 0.014
regulation of cellular component size GO:0032535 98 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
cytoplasmic transport GO:0016482 130 0.014
regulation of cell death GO:0010941 173 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
activation of jun kinase activity GO:0007257 3 0.014
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.014
meiotic nuclear division GO:0007126 151 0.014
protein complex assembly GO:0006461 200 0.014
macromolecular complex assembly GO:0065003 256 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
positive regulation of protein catabolic process GO:0045732 34 0.014
cytokinetic cell separation GO:0000920 1 0.014
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.014
synapse organization GO:0050808 196 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
regulation of cell proliferation GO:0042127 163 0.014
epithelial cell migration GO:0010631 148 0.014
positive regulation of wnt signaling pathway GO:0030177 25 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
Human
spermatid differentiation GO:0048515 114 0.013
negative regulation of developmental process GO:0051093 201 0.013
single organism nuclear import GO:1902593 51 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
mitochondrion organization GO:0007005 65 0.013
positive regulation of cell communication GO:0010647 250 0.013
digestive system development GO:0055123 149 0.013
mucosal immune response GO:0002385 10 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
spermatogenesis GO:0007283 200 0.013
oocyte development GO:0048599 124 0.013
protein complex biogenesis GO:0070271 201 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
regulation of protein serine threonine kinase activity GO:0071900 25 0.013
neuroblast division GO:0055057 35 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
positive regulation of protein kinase activity GO:0045860 25 0.012
reproductive system development GO:0061458 74 0.012
amide biosynthetic process GO:0043604 42 0.012
border follicle cell migration GO:0007298 113 0.012
smoothened signaling pathway GO:0007224 49 0.012
response to peptide hormone GO:0043434 29 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
sex differentiation GO:0007548 81 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
cellular protein catabolic process GO:0044257 83 0.012
positive regulation of kinase activity GO:0033674 25 0.012
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.012
positive regulation of growth GO:0045927 75 0.012
regulation of protein import into nucleus GO:0042306 28 0.012
dna amplification GO:0006277 11 0.012
meiotic cell cycle process GO:1903046 132 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
response to hypoxia GO:0001666 53 0.011
death GO:0016265 284 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
golgi vesicle transport GO:0048193 27 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
oxoacid metabolic process GO:0043436 103 0.011
regulation of endopeptidase activity GO:0052548 36 0.011
Human
peptidyl threonine modification GO:0018210 3 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of viral genome replication GO:0045069 4 0.011
regulation of cell projection assembly GO:0060491 30 0.011
negative regulation of catalytic activity GO:0043086 42 0.010
Human
single organism biosynthetic process GO:0044711 206 0.010
inositol lipid mediated signaling GO:0048017 4 0.010
positive regulation of protein import into nucleus GO:0042307 21 0.010
dorsal closure GO:0007391 79 0.010
protein processing GO:0016485 68 0.010
Human
antimicrobial humoral response GO:0019730 99 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
phosphatidylinositol mediated signaling GO:0048015 4 0.010
maintenance of protein location in cell GO:0032507 26 0.010
dephosphorylation GO:0016311 51 0.010

POSH disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060