Drosophila melanogaster

22 known processes

ea (Dmel_CG4920)

easter

(Aliases: Dmel\CG4920,SP24,EA,c-SP24,CG4920)

ea biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dorsal ventral axis specification GO:0009950 66 0.450
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.350
embryo development ending in birth or egg hatching GO:0009792 152 0.345
protein maturation GO:0051604 71 0.310
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.274
cell division GO:0051301 248 0.274
cuticle development GO:0042335 86 0.221
embryonic development via the syncytial blastoderm GO:0001700 148 0.201
response to fungus GO:0009620 50 0.153
Fly
embryonic morphogenesis GO:0048598 206 0.150
regulation of epithelial cell proliferation GO:0050678 4 0.145
establishment of localization in cell GO:0051649 402 0.137
molting cycle chitin based cuticle GO:0007591 56 0.122
establishment of nucleus localization GO:0040023 26 0.121
morphogenesis of embryonic epithelium GO:0016331 94 0.120
axon development GO:0061564 297 0.113
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.107
oocyte axis specification GO:0007309 108 0.094
positive regulation of antifungal peptide production GO:0002804 6 0.090
toll signaling pathway GO:0008063 25 0.090
Fly
oocyte differentiation GO:0009994 145 0.088
protein processing GO:0016485 68 0.086
positive regulation of signal transduction GO:0009967 223 0.085
Fly
motor neuron axon guidance GO:0008045 58 0.084
regulation of defense response to fungus GO:1900150 6 0.083
chorion containing eggshell formation GO:0007304 105 0.081
organic hydroxy compound metabolic process GO:1901615 83 0.080
Fly
positive regulation of cell communication GO:0010647 250 0.078
Fly
embryonic axis specification GO:0000578 107 0.077
antifungal peptide biosynthetic process GO:0002783 5 0.073
response to light stimulus GO:0009416 124 0.073
response to biotic stimulus GO:0009607 294 0.072
Fly
oocyte construction GO:0007308 112 0.072
positive regulation of response to stimulus GO:0048584 323 0.071
Fly
dorsal ventral pattern formation GO:0009953 133 0.071
regulation of pole plasm oskar mrna localization GO:0007317 27 0.067
defense response to bacterium GO:0042742 178 0.066
Fly
molting cycle GO:0042303 56 0.065
antifungal humoral response GO:0019732 12 0.065
negative regulation of cell communication GO:0010648 223 0.063
regulation of antifungal peptide production GO:0002788 6 0.062
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.062
establishment of organelle localization GO:0051656 122 0.057
innate immune response GO:0045087 144 0.055
Fly
positive regulation of signaling GO:0023056 243 0.054
Fly
small molecule metabolic process GO:0044281 305 0.053
determination of dorsal ventral asymmetry GO:0048262 3 0.052
terminal region determination GO:0007362 25 0.052
mitotic nuclear division GO:0007067 213 0.051
columnar cuboidal epithelial cell development GO:0002066 249 0.051
positive regulation of transcription dna templated GO:0045893 266 0.049
positive regulation of rna biosynthetic process GO:1902680 266 0.049
axis specification GO:0009798 167 0.048
transcription from rna polymerase ii promoter GO:0006366 368 0.047
chemotaxis GO:0006935 249 0.046
response to radiation GO:0009314 155 0.046
cytokinesis GO:0000910 90 0.045
germ cell migration GO:0008354 43 0.045
negative regulation of cellular metabolic process GO:0031324 382 0.044
cellular ketone metabolic process GO:0042180 24 0.043
defense response GO:0006952 300 0.042
Fly
body morphogenesis GO:0010171 2 0.042
oocyte development GO:0048599 124 0.041
positive regulation of antimicrobial peptide production GO:0002225 28 0.041
Fly
negative regulation of cell cycle process GO:0010948 109 0.041
endodermal cell fate commitment GO:0001711 3 0.041
regionalization GO:0003002 416 0.041
mesenchymal cell differentiation GO:0048762 1 0.040
neurological system process GO:0050877 358 0.040
tripartite regional subdivision GO:0007351 103 0.040
taxis GO:0042330 304 0.040
endodermal cell differentiation GO:0035987 3 0.040
torso signaling pathway GO:0008293 21 0.039
nucleus localization GO:0051647 34 0.039
camera type eye development GO:0043010 4 0.038
positive regulation of nucleic acid templated transcription GO:1903508 266 0.038
cell cycle checkpoint GO:0000075 95 0.037
single organism intracellular transport GO:1902582 207 0.037
kidney development GO:0001822 3 0.036
positive regulation of cell migration GO:0030335 2 0.036
immune system process GO:0002376 347 0.036
Fly
regulation of protein metabolic process GO:0051246 256 0.036
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.034
eggshell chorion assembly GO:0007306 66 0.034
organic substance transport GO:0071702 257 0.034
intracellular transport GO:0046907 228 0.034
eggshell formation GO:0030703 105 0.034
immune response activating signal transduction GO:0002757 2 0.033
establishment of protein localization GO:0045184 163 0.033
antifungal peptide production GO:0002781 7 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.033
pole plasm rna localization GO:0007316 52 0.032
protein modification process GO:0036211 438 0.032
axonogenesis GO:0007409 290 0.032
macromolecular complex assembly GO:0065003 256 0.031
regulation of molecular function GO:0065009 217 0.031
positive regulation of gene expression GO:0010628 290 0.031
pole plasm assembly GO:0007315 61 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
defense response to gram positive bacterium GO:0050830 41 0.031
Fly
chemosensory behavior GO:0007635 106 0.031
single organism biosynthetic process GO:0044711 206 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
Fly
actin cytoskeleton organization GO:0030036 206 0.030
negative regulation of gene expression GO:0010629 387 0.030
mitotic cytokinesis GO:0000281 50 0.030
response to oxygen containing compound GO:1901700 200 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
regulation of cellular localization GO:0060341 136 0.029
regulation of localization GO:0032879 275 0.029
cognition GO:0050890 141 0.029
regulation of embryonic pattern specification GO:1902875 27 0.029
response to organic substance GO:0010033 284 0.028
peripheral nervous system development GO:0007422 52 0.028
cellular protein modification process GO:0006464 438 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
oocyte microtubule cytoskeleton organization GO:0016325 35 0.027
nuclear import GO:0051170 51 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
protein transport GO:0015031 155 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
oxoacid metabolic process GO:0043436 103 0.026
response to organic cyclic compound GO:0014070 89 0.026
cell projection assembly GO:0030031 94 0.026
phosphorylation GO:0016310 294 0.026
dorsal closure GO:0007391 79 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
Fly
single organism nuclear import GO:1902593 51 0.025
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.025
regulation of cellular component movement GO:0051270 42 0.024
developmental maturation GO:0021700 172 0.024
regulation of hemocyte differentiation GO:0045610 22 0.024
protein localization GO:0008104 284 0.024
single organism behavior GO:0044708 391 0.024
lipid biosynthetic process GO:0008610 46 0.024
oocyte dorsal ventral axis specification GO:0007310 34 0.023
regulation of transport GO:0051049 181 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
ameboidal type cell migration GO:0001667 151 0.023
negative regulation of phosphorus metabolic process GO:0010563 45 0.023
regulation of toll signaling pathway GO:0008592 17 0.023
Fly
negative regulation of epithelial cell proliferation GO:0050680 4 0.023
positive regulation of cell motility GO:2000147 3 0.023
pigment metabolic process GO:0042440 84 0.023
Fly
neuron projection guidance GO:0097485 241 0.023
response to bacterium GO:0009617 198 0.022
Fly
intracellular signal transduction GO:0035556 300 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
eye development GO:0001654 323 0.022
regulation of programmed cell death GO:0043067 152 0.022
synaptic transmission GO:0007268 288 0.022
response to external biotic stimulus GO:0043207 293 0.021
Fly
notch signaling pathway GO:0007219 120 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.021
head involution GO:0008258 35 0.021
regulation of epithelial cell differentiation GO:0030856 4 0.021
regulation of cell development GO:0060284 215 0.020
regulation of cell death GO:0010941 173 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
anterior posterior axis specification embryo GO:0008595 103 0.020
regulation of apoptotic process GO:0042981 130 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
organelle fission GO:0048285 340 0.020
regulation of response to stress GO:0080134 200 0.020
Fly
central nervous system development GO:0007417 201 0.020
cell motility GO:0048870 251 0.020
positive regulation of cell differentiation GO:0045597 64 0.019
digestive tract morphogenesis GO:0048546 127 0.019
response to nitrogen compound GO:1901698 90 0.019
protein targeting GO:0006605 64 0.019
blood circulation GO:0008015 26 0.019
negative regulation of molecular function GO:0044092 51 0.019
positive regulation of multi organism process GO:0043902 40 0.019
Fly
single organism catabolic process GO:0044712 228 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
defense response to other organism GO:0098542 225 0.019
Fly
negative regulation of signaling GO:0023057 219 0.019
positive regulation of developmental process GO:0051094 143 0.019
macromolecule catabolic process GO:0009057 161 0.018
response to alcohol GO:0097305 95 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
Fly
organelle localization GO:0051640 148 0.018
retina development in camera type eye GO:0060041 4 0.018
cuticle pattern formation GO:0035017 27 0.018
protein localization to organelle GO:0033365 82 0.018
regulation of secretion by cell GO:1903530 39 0.018
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.018
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
cell migration GO:0016477 238 0.017
vesicle mediated transport GO:0016192 381 0.017
Fly
nuclear division GO:0000280 332 0.017
organic acid metabolic process GO:0006082 103 0.017
urogenital system development GO:0001655 72 0.017
aging GO:0007568 143 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
olfactory behavior GO:0042048 97 0.016
regulation of protein transport GO:0051223 57 0.016
larval development GO:0002164 104 0.016
lipid metabolic process GO:0006629 121 0.016
regulation of neurotransmitter levels GO:0001505 38 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
epithelial cell development GO:0002064 274 0.016
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
epithelial cell migration GO:0010631 148 0.016
fat soluble vitamin biosynthetic process GO:0042362 1 0.015
regulation of cell division GO:0051302 72 0.015
ketone biosynthetic process GO:0042181 16 0.015
single organism cellular localization GO:1902580 180 0.015
gastrulation GO:0007369 70 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
intracellular protein transport GO:0006886 104 0.015
negative regulation of autophagy GO:0010507 16 0.015
response to lipopolysaccharide GO:0032496 4 0.015
positive regulation of developmental growth GO:0048639 62 0.015
positive regulation of cellular amide metabolic process GO:0034250 26 0.015
Fly
microtubule anchoring GO:0034453 11 0.015
cell cycle phase transition GO:0044770 140 0.015
positive regulation of immune effector process GO:0002699 28 0.015
Fly
regulation of secretion GO:0051046 44 0.015
ovarian follicle cell migration GO:0007297 121 0.015
cellular response to organic substance GO:0071310 132 0.015
spermatogenesis GO:0007283 200 0.015
regulation of hydrolase activity GO:0051336 97 0.015
humoral immune response GO:0006959 117 0.015
Fly
negative regulation of rna metabolic process GO:0051253 251 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
instar larval development GO:0002168 55 0.014
response to endogenous stimulus GO:0009719 119 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
chitin based cuticle development GO:0040003 49 0.014
response to organophosphorus GO:0046683 2 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
regulation of defense response GO:0031347 102 0.014
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.014
negative regulation of cellular catabolic process GO:0031330 34 0.014
protein targeting to nucleus GO:0044744 51 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
regulation of protein modification process GO:0031399 112 0.014
negative regulation of cell death GO:0060548 81 0.014
synaptic growth at neuromuscular junction GO:0051124 119 0.014
death GO:0016265 284 0.013
developmental growth GO:0048589 280 0.013
anion homeostasis GO:0055081 3 0.013
mapk cascade GO:0000165 107 0.013
hormone metabolic process GO:0042445 33 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
negative regulation of proteolysis GO:0045861 31 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
compound eye development GO:0048749 307 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
male gamete generation GO:0048232 201 0.013
response to other organism GO:0051707 293 0.013
Fly
regulation of organelle organization GO:0033043 196 0.013
synapse organization GO:0050808 196 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
actin filament based process GO:0030029 220 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.013
cell cell junction assembly GO:0007043 38 0.013
antimicrobial humoral response GO:0019730 99 0.013
Fly
tissue morphogenesis GO:0048729 297 0.013
negative regulation of transcription dna templated GO:0045892 237 0.012
synapse assembly GO:0007416 143 0.012
organophosphate metabolic process GO:0019637 195 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
apoptotic process GO:0006915 159 0.012
regulation of protein processing GO:0070613 32 0.012
regulation of cell projection organization GO:0031344 92 0.012
regulation of phosphatase activity GO:0010921 3 0.012
organic substance catabolic process GO:1901575 308 0.012
regulation of cell differentiation GO:0045595 302 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
nephron epithelium development GO:0072009 3 0.012
embryonic pattern specification GO:0009880 174 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
positive regulation of cytoskeleton organization GO:0051495 21 0.012
negative regulation of signal transduction GO:0009968 206 0.012
regulation of response to nutrient levels GO:0032107 18 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
digestive system development GO:0055123 149 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
multicellular organism growth GO:0035264 46 0.011
ecdysteroid biosynthetic process GO:0045456 15 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of protein polymerization GO:0032271 28 0.011
mesenchymal cell development GO:0014031 1 0.011
smoothened signaling pathway GO:0007224 49 0.011
response to wounding GO:0009611 94 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
cytoplasmic transport GO:0016482 130 0.011
adult behavior GO:0030534 137 0.011
renal system development GO:0072001 72 0.011
epithelium migration GO:0090132 148 0.011
regulation of rna splicing GO:0043484 69 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
pole plasm mrna localization GO:0019094 49 0.011
endocytosis GO:0006897 310 0.011
Fly
muscle tissue morphogenesis GO:0060415 2 0.011
actin filament organization GO:0007015 126 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of cell cycle process GO:0010564 181 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
positive regulation of protein complex assembly GO:0031334 22 0.010
regulation of immune system process GO:0002682 176 0.010
Fly
ovarian follicle cell development GO:0030707 248 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
digestive tract development GO:0048565 149 0.010
response to growth factor GO:0070848 31 0.010
regulation of phosphorylation GO:0042325 147 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
neurotransmitter transport GO:0006836 37 0.010
defense response to fungus GO:0050832 48 0.010
Fly
glutamate metabolic process GO:0006536 5 0.010
protein heterooligomerization GO:0051291 4 0.010

ea disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
cancer DOID:162 0 0.027
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.012